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Description

Objectives:

-To test the hypothesis that canonical Notch signaling influence vascular function by regulating PVAT-derived vascular relaxation factors.

-To determine how overexpression of Notch signaling or loss of the key Notch signaling component influence PVAT function.

Publication Date

2021

Publisher

Maine Medical Center

City

Portland, Maine

Keywords

Perivascular Adipose Tissue, Diet-induced Obesity, Cardiovascular Disease, Vascular Function, Canonical Notch Signaling, PVAT-derived Vascular Relaxation Factors

Disciplines

Medical Biochemistry | Medical Education

Notch signaling regulates perivascular adipose tissue (PVAT) function during diet-induced obesity

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