Title

Triple Negative Breast Cancer

Document Type

Video

Publication Date

11-13-2019

Institution/Department

Grand Rounds, Maine Medical Center, Oncology

MeSH Headings

Triple Negative Breast Neoplasms, Receptors, Progesterone

Abstract

Conclusion:

Breast cancer is thought of as three different diseases based on ER/PR/HER2 expression (ER+/PR+/HER2-,HER2+, triple negative)

TNBC itself shows significant molecular diversity

Modern treatment of TNBC is influenced by

-Germline BRCA mutation status

-Tumor expression of PD-L1

TNBC is model for modern oncology treatment, which is becoming increasingly molecular and based on genomic profiling of tumors

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