Limited clinical utility of follow-up blood cultures in patients with streptococcal bacteremia: an opportunity for blood culture stewardship

Emily A. Siegrist, Maine Medical Center
Minkey Wungwattana, Maine Medical Center
Leyla Azis, Maine Medical Center
Patricia Stogsdill, Maine Medical Center
Wendy Y. Craig, Maine Medical Center
Kristina E. Rokas, Maine Medical Center


Background: The value of positive follow-up blood cultures (FUBCs) in streptococcal bacteremia has not been well defined. Therefore, we explored the frequency of and risk factors for positive FUBC in a retrospective cohort of patients with streptococcal bacteremia.

Methods: Adults ≥18 years of age, admitted with at least 1 positive blood culture for

Results: In our single-center cohort, we identified 590 patients with streptococcal bacteremia, and 314 patients met inclusion criteria. Ten patients had FUBC with

Conclusions: Follow-up blood cultures among patients with streptococcal BSI are rarely positive. Clinicians could consider limiting follow-up blood cultures in patients at low risk for deep-seated streptococcal infections, persistent bacteremia, or endovascular infection.