Conceptual, methodological, and ethical problems in communicating uncertainty in clinical evidence.

Document Type

Article

Publication Date

2-1-2013

Institution/Department

Center for Outcomes Research and Evaluation, Maine Medical Center Research Institute

Journal Title

Medical care research and review : MCRR

MeSH Headings

Communication, Decision Making, Evidence-Based Medicine, Humans, Physician-Patient Relations, Probability, Uncertainty

Abstract

The communication of uncertainty in clinical evidence is an important endeavor that poses difficult conceptual, methodological, and ethical problems. Conceptual problems include logical paradoxes in the meaning of probability and "ambiguity"--second-order uncertainty arising from the lack of reliability, credibility, or adequacy of probability information. Methodological problems include questions about optimal methods for representing fundamental uncertainties and for communicating these uncertainties in clinical practice. Ethical problems include questions about whether communicating uncertainty enhances or diminishes patient autonomy and produces net benefits or harms. This article reviews the limited but growing literature on these problems and efforts to address them and identifies key areas of focus for future research. It is argued that the critical need moving forward is for greater conceptual clarity and consistent representational methods that make the meaning of various uncertainties understandable, and for clinical interventions to support patients in coping with uncertainty in decision making.

ISSN

1552-6801

First Page

14

Last Page

14

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