Document Type

Patent

Publication Date

8-13-2002

Patent Number

6433138

Abstract

This invention relates to therapeutic and diagnostic methods and compositions based on Jagged/Notch proteins and nucleic acids, and on the role of their signaling pathway in endothelial cell migration and/or differentiation. In addition, this invention provides a substantially purified Jagged protein, as well as a substantially purified nucleic acid molecule or segment thereof encoding Jagged protein, or a functionally equivalent derivative, or allelic or species variant thereof.

Application Number

09199865

Institution/Department

Maine Medical Center, MaineHealth Institute for Research

Assignees

MaineHealth Institute for Research

Filing Date

11/25/1998

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