Document Type
Patent
Publication Date
10-7-2003
Patent Number
6630325
Abstract
The invention relates to novel nucleic acids encoding a mammalian adventitia inducible and bone expressed gene designated REMODEL, and proteins encoded thereby, whose expression is increased in certain diseases, disorders, or conditions, including, but not limited to, negative remodeling, arterial restenosis, vessel injury, ectopic ossification, fibrosis, and the like. REMODEL also plays a role in cell-cell and cell-matrix adhesion, bone density, bone formation, dorsal closure, and is associated with spina bifida-like phenotype. The invention further relates to methods of treating and detecting these diseases, disorders or conditions, comprising modulating or detecting REMODEL expression and/or production of REMODEL polypeptide.
Application Number
09692081
Institution/Department
Maine Medical Center, MaineHealth Institute for Research
Recommended Citation
Lindner, Volkhard and Friesel, Robert E., "Compositions, Methods And Kits Relating To Remodel" (2003). MaineHealth Patents. 20.
https://knowledgeconnection.mainehealth.org/patents/20
Filing Date
10/19/2000
