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The purpose of this multi-center, double-blinded pilot study was to determine if EVOO has a positive effect on HDL cholesterol levels and anti-inflammatory markers for subjects diagnosed with CVD and to determine if the polyphenol concentration is proportional to those effects. Subjects completed consecutive 28-day periods (with a 14- day washout between) in which they will either consume the low polyphenol EVOO daily or the high polyphenol EVOO. In a double-blinded manner, each subject was his or her own control with a 14-day washout between study periods. HDL levels and other parameters were be measured after each period of the protocol. We anticipated HDL levels will improve with both olive oils. We expect the high polyphenol concentration EVOO would show a greater effect than the EVOO with a low polyphenol concentration.
Pen Bay Medical Center- Maine Health
Knight, Caroline; Hamill, Ralph; Brady, Katherine; and Kozidis, Stacia, "A Multicenter Pilot Study to Evaluate the Effect of EVOO on Lipid Parameters" (2022). Costas T. Lambrew Research Retreat 2022. 38.