Electroconvulsive therapy in an adolescent with autism and bipolar I disorder.
The journal of ECT
Adolescent, Aggression, Antimanic Agents, Antipsychotic Agents, Autistic Disorder, Behavior, Bipolar Disorder, Electroconvulsive Therapy, Humans, Hypnotics and Sedatives, Lithium Carbonate, Male, Self-Injurious Behavior
OBJECTIVES: We report a positive response to electroconvulsive therapy in a severely functionally impaired adolescent with autistic disorder and classic bipolar I disorder, including an episodic pattern of decreased need for sleep, hypersexuality, expansive and agitated affect, aggression, self-injury, and property destruction.
METHODS: After ineffective trials of mood stabilizers and antipsychotics as well as inability to sustain a positive response to lithium due to medication noncompliance, a course of acute and maintenance electroconvulsive therapy was attempted.
RESULTS: A marked and sustained improvement across all symptom categories, as measured by directly observed frequency counts of target behaviors in an inpatient setting, was obtained.
CONCLUSIONS: Electroconvulsive therapy should be considered a potentially useful intervention in cases of children with autistic disorder and a severe comorbid affective disorder.
Siegel, Matthew; Milligan, Briana; Robbins, Douglas; and Prentice, Glenn, "Electroconvulsive therapy in an adolescent with autism and bipolar I disorder." (2012). Maine Behavioral Health. 7.