Submissions from 2023
Gaps in Cystic Fibrosis Care Are Associated with Reduced Lung Function in the U.S. Cystic Fibrosis Foundation Patient Registry, Edmund H. Sears, Alexandra C. Hinton, Sara Lopez-Pintado, Christine W. Lary, and Jonathan B. Zuckerman
Intensive Care Interventions Among Children With Toxicologic Exposures to Cardiovascular Medications, Michael D. Simpson, C James Watson, James D. Whitledge, Michael C. Monuteaux, and Michele M. Burns
Submissions from 2022
Early vs Standard Approach to Tracheostomy and Functional Outcome Among Patients With Severe Stroke Receiving Mechanical Ventilation-Reply, Julian Bösel, Silvia Schönenberger, and David B. Seder
Prospective Validation of Sedation Scale Scores That Identify Light Sedation: A Pilot Study, Caitlin Brown, Pasquale Joseph Marotta, Richard R. Riker, Ashley D. Eldridge, Gilles L. Fraser, and Teresa L. May
Level of sedation in critically ill adult patients: a protocol for a systematic review with meta-analysis and trial sequential analysis, Ameldina Ceric, Johan Holgersson, Teresa May, Markus B. Skrifvars, Johanna Hästbacka, Manoj Saxena, Anders Aneman, Anthony Delaney, Michael C. Reade, Candice Delcourt, Janus Jakobsen, and Niklas Nielsen
Ceftriaxone to PRevent pneumOnia and inflammaTion aftEr Cardiac arresT (PROTECT): study protocol for a randomized, placebo-controlled trial, David J. Gagnon, Sergey V. Ryzhov, Meghan A. May, Richard R. Riker, Bram Geller, Teresa L. May, Sarah Bockian, Joanne T. deKay, Ashley Eldridge, Thomas Van der Kloot, Patricia Lerwick, Christine Lord, F Lee Lucas, Patrick Mailloux, Barbara McCrum, Meghan Searight, Joel Wirth, Jonathan Zuckerman, Douglas Sawyer, and David B. Seder
Evaluation of the safety of a novel peripheral vasopressor pilot program and the impact on central line placement in medical and surgical intensive care units, Kristen Marti, Christopher Hartley, Elizabeth Sweeney, John Mah, and Nicholas Pugliese
Impact of community-level socioeconomic disparities on quality of life after burn injury: A Burn Model Systems Database study, Stephanie Mason, Emma Gause, Kara McMullen, Sha'Chia Murphy, Stephen Sibbett, Radha Holavanahalli, Jeffrey Schneider, Nicole Gibran, and Lewis E. Kazis
Cardiac Arrest Treatment Center Differences in Sedation and Analgesia Dosing During Targeted Temperature Management, Teresa L. May, David B. Seder, and Richard R. Riker
Letter to the Editor: "Midodrine to liberate ICU patients from intravenous vasopressors: Another negative fixed-dose trial"., Richard R Riker and David J Gagnon
Bronchial penetration of migrated Temporary Epicardial Pacing Wire with bronchoscopic extraction, Christopher G. Roy and Nicholas A. Pozzessere
Opioid Prescribing Patterns Before, During, and After Critical Illness: An Observational Study, Chelsea Wampole, Ariel McKenna, Richard R. Riker, Teresa L. May, David B. Seder, Dawn Abram, Gilles L. Fraser, and David J. Gagnon
Analgesia and Sedation in Critically Ill Patients With Burns, Paige Weaver
Submissions from 2020
The association of partial pressures of oxygen and carbon dioxide with neurological outcome after out-of-hospital cardiac arrest: an explorative International Cardiac Arrest Registry 2.0 study., Florian Ebner, Richard R Riker, Zana Haxhija, David B Seder, Teresa L May, Susann Ullén, Pascal Stammet, Karen Hirsch, Sune Forsberg, Allison Dupont, Hans Friberg, John A McPherson, Eldar Søreide, Josef Dankiewicz, Tobias Cronberg, and Niklas Nielsen
Amantadine and Modafinil as Neurostimulants During Post-stroke Care: A Systematic Review, David J. Gagnon, Angela M. Leclerc, Richard R. Riker, Caitlin S. Brown, Teresa May, Kristina Nocella, Jennifer Cote, Ashley Eldridge, and David B. Seder
Outcomes of catheter-directed versus systemic thrombolysis for the treatment of pulmonary embolism: A real-world analysis of national administrative claims., Bram J Geller, Srinath Adusumalli, Steven C Pugliese, Sameed Ahmed M Khatana, Ashwin Nathan, Ido Weinberg, Michael R Jaff, Taisei Kobayashi, Jeremy A Mazurek, Sameer Khandhar, Lin Yang, Peter W Groeneveld, and Jay S Giri
Functional outcomes associated with varying levels of targeted temperature management after out-of-hospital cardiac arrest - An INTCAR2 registry analysis., Jesper Johnsson, Josefine Wahlström, Josef Dankiewicz, Martin Annborn, Sachin Agarwal, Allison Dupont, Sune Forsberg, Hans Friberg, Robert Hand, Karen G Hirsch, Teresa May, John A McPherson, Michael R Mooney, Nainesh Patel, Richard R Riker, Pascal Stammet, Eldar Søreide, David B Seder, and Niklas Nielsen
Postgraduate Training Options for Advanced Practice Providers in General and Trauma/Surgical Critical Care, Angela M. Leclerc, Sarah Vanderlin, Melissa Ricker, Annika Kay, and Aimee Abide
Serum soluble receptor for advanced glycation end-products (sRAGE) in infants with bronchiolitis: Associations with acute severity and recurrent wheeze., Jason T Patregnani, Michimasa Fujiogi, Carlos A Camargo, Bonnie A Brooks, Claire E Hoptay, Jonathan M Mansbach, Stephen J Teach, Robert J Freishtat, and Kohei Hasegawa
Delirium-Beyond the CAM-ICU., Richard R Riker and Gilles L Fraser
Early cerebral edema after cardiac arrest and its ramifications., Jonathan Rud, Teresa L May, Richard R Riker, and David B Seder
Changes in EBUS procedures and molecular yields at MMC 2013-2017, Joseph Scrobola and Edmund Sears
Intubation of the COVID-19 Patient, Edmund Sears
Cystic Fibrosis Telemonitoring in a Small Rural Maine Cohort: A Feasibility Study, Edmund Sears, Philip Stone, Alicia Murray, and Thomas Desjardins
Serum Glial Fibrillary Acidic Protein in Acute Stroke, David B. Seder
Vasopressin-Induced Hyponatremia in Patients with Aneurysmal Subarachnoid Hemorrhage: A Case Series, Hilamber Subba, Richard Riker, Susan Dunn, Teresa May, David Gagnon, and David Seder
Nordihydroguaiaretic acid reduces secondary organ injury in septic rats after cecal ligation and puncture., Michael E Zubrow, Susan S Margulies, and Nadir Yehya
Submissions from 2019
The Influence of Therapeutics on Prognostication After Cardiac Arrest., Sachin Agarwal, Nicholas Morris, Caroline Der-Nigoghossian, Teresa May, and Daniel Brodie
Neurocardiac risk stratification 6 hours after resuscitation from cardiac arrest, A Bilkanovic, Z Haxhija, L Lucas, J Dziodzio, R R. Riker, T May, H Friberg, and D B. Seder
Support for antibiotic prophylaxis during targeted temperature management after cardiac arrest: Heating up or cooling down?, David J Gagnon and David B Seder
Sleep disruption and delirium in the pediatric CICU., Jillian Gregory, Anna Brown, and Sapna Kudchadkar
Early withdrawal of life support after resuscitation from cardiac arrest is common and may result in additional deaths., Teresa L May, Robin Ruthazer, Richard R Riker, Hans Friberg, Nainesh Patel, Eldar Soreide, Robert Hand, Pascal Stammet, Allison Dupont, Karen G Hirsch, Sachin Agarwal, Michael J Wanscher, Josef Dankiewicz, Niklas Nielsen, David B Seder, and David M Kent
Tracheostomy Practices in Neurocritical Care., David B Seder
A woman with nonresolving fever and bilateral pulmonary infiltrates., Philip C Stone, Edmund H Sears, and Jonathan B Zuckerman
Low-dose compared to manufacturer-recommended dose four-factor prothrombin complex concentrate for acute warfarin reversal., Wesley Zemrak, Francis Manuel, Kathryn E Smith, Stephen Rolfe, Timothy Hayes, Robert L Trowbridge, Brian Carlone, and David Seder
Submissions from 2018
Interpreting and Implementing the 2018 Pain, Agitation/Sedation, Delirium, Immobility, and Sleep Disruption Clinical Practice Guideline., Michele C Balas, Gerald L Weinhouse, Linda Denehy, Gerald Chanques, Bram Rochwerg, Cheryl J Misak, Yoanna Skrobik, John W Devlin, and Gilles L Fraser
Derivation and validation of the CREST model for very early prediction of circulatory etiology death in patients without ST-segment-elevation myocardial infarction after cardiac arrest., Karen E Bascom, John Dziodzio, Samip Vasaiwala, Michael Mooney, Nainesh Patel, John McPherson, Paul McMullan, Barbara Unger, Niklas Nielsen, Hans Friberg, Richard R Riker, Karl B Kern, Christine W Duarte, and David B Seder
Azithromycin for Early Pseudomonas Infection in Cystic Fibrosis. The OPTIMIZE Randomized Trial., Nicole Mayer-Hamblett, George Retsch-Bogart, Margaret Kloster, Frank Accurso, Margaret Rosenfeld, Gary Albers, Philip Black, Perry Brown, AnneMarie Cairns, Stephanie D Davis, Gavin R Graff, Gwendolyn S Kerby, David Orenstein, Rachael Buckingham, Bonnie W Ramsey, and OPTIMIZE Study Group
Complex Legacy of the Target Temperature Management Trial., Teresa L May, Richard R Riker, and David B Seder
Long-term risk of seizures among cardiac arrest survivors., Nicholas A Morris, Teresa L May, Melissa Motta, Sachin Agarwal, and Hooman Kamel
Use of ceftolozane-tazobactam in a cystic fibrosis patient with multidrug-resistant pseudomonas infection and renal insufficiency., Katie Stokem, Jonathan B Zuckerman, David P Nicolau, Minkey Wungwattana, and Edmund H Sears
Submissions from 2017
Development of a Traumatic Brain Injury (TBI) Order Set at Maine Medical Center, Sarah Bockian, Emily Esslinger, and Martha Weatherhead
What is the role of oral prostacyclin pathway medications in pulmonary arterial hypertension management?, Rama El Yafawi and Joel A Wirth
Repurposing valproate, enteral clonidine, and phenobarbital for comfort in adult ICU patients: a literature review with practical considerations., David J Gagnon, Gabriel V Fontaine, Richard R Riker, and Gilles L Fraser
Stroke and myocardial infarction following bronchial artery embolization in a cystic fibrosis patient., Matt Hoffman, Joseph P Gerding, and Jonathan B Zuckerman
Five-year trends of critical care practice and outcomes., Craig M Lilly, Sunil Swami, Xinggang Liu, Richard R Riker, and Omar Badawi
The implementation of targeted temperature management: an evidence-based guideline from the Neurocritical Care Society., Lori Kennedy Madden, Michelle Hill, Teresa L May, Theresa Human, Mary McKenna Guanci, Judith Jacobi, Melissa V Moreda, and Neeraj Badjatia
Cefepime-induced neurotoxicity: a systematic review., Lauren E Payne, David J Gagnon, Richard R Riker, David B Seder, Elizabeth K Glisic, Jane G Morris, and Gilles L Fraser
Emergency neurological life support: airway, ventilation, and sedation., Venkatakrishna Rajajee, Becky Riggs, and David B. Seder
Valproate protein binding is highly variable in ICU patients and not predicted by total serum concentrations: a case series and literature review., Richard R Riker, David J Gagnon, Colman Hatton, Teresa May, David B Seder, Katie Stokem, and Gilles L Fraser
Caution warranted regarding transfusion for subarachnoid hemorrhage., Richard R Riker and David B Seder
Airway management and mechanical ventilation in acute brain injury., D B Seder and J Bösel
Does medication safety and diversion education improve medication securement practices in SCU compared to current practice?, Natasha Stankiewicz
Guidelines for family-centered care in neuro-ICU populations: caveats for routine palliative care., Michel T Torbey, Gretchen M Brophy, Panayiotis N Varelas, Julian Bösel, Edward Manno, Mary Kay Bader, Jose I Suarez, David Seder, and W David Freeman
Low-dose prothrombin complex concentrate for warfarin-associated intracranial hemorrhage with INR less than 2.0., Wesley R Zemrak, Kathryn E Smith, Stephen S Rolfe, Teresa May, Robert L Trowbridge, Timothy L Hayes, Gene A Grindlinger, and David B Seder
Submissions from 2016
Clinafloxacin for treatment of Burkholderia cenocepacia infection in a cystic fibrosis patient, Akshu Balwan, David P Nicolau, Minkey Wungwattana, Jonathan B Zuckerman, and Valerie Waters
Managing the patient with pulmonary hypertension: specialty care centers, coordinated care, and patient support., Murali M Chakinala, Maribeth Duncan, and Joel Wirth
Clinical and research considerations for patients with hypertensive acute heart failure: a consensus statement from the Society for Academic Emergency Medicine and the Heart Failure Society of America Acute Heart Failure Working Group., Sean P Collins, Phillip D Levy, Jennifer L Martindale, Mark E Dunlap, Alan B Storrow, Peter S Pang, Nancy M Albert, G Michael Felker, Gregory J Fermann, Gregg C Fonarow, Michael M Givertz, Judd E Hollander, David E Lanfear, Daniel J Lenihan, JoAnn M Lindenfeld, W Frank Peacock, Douglas B. Sawyer, John R Teerlink, and Javed Butler
Clinical and research considerations for patients with hypertensive acute heart failure: a consensus statement from the Society of Academic Emergency Medicine and the Heart Failure Society of America Acute Heart Failure Working Group., Sean P Collins, Phillip D Levy, Jennifer L Martindale, Mark E Dunlap, Alan B Storrow, Peter S Pang, Nancy M Albert, G Michael Felker, Gregory J Fermann, Gregg C Fonarow, Michael M Givertz, Judd E Hollander, David J Lanfear, Daniel J Lenihan, JoAnn M Lindenfeld, W Frank Peacock, Douglas B. Sawyer, John R Teerlink, and Javed Butler
Intended and unintended consequences of constraining clinician prescribing: the case of antipsychotics., John W Devlin, Pamela Smithburger, Jason M Kane, Gilles L. Fraser, and Yoanna Skrobik
The Insertion and Management of External Ventricular Drains: An Evidence-Based Consensus Statement : A Statement for Healthcare Professionals from the Neurocritical Care Society., Herbert I Fried, Barnett R Nathan, A Shaun Rowe, Joseph M Zabramski, Norberto Andaluz, Adarsh Bhimraj, Mary McKenna Guanci, David B Seder, and Jeffrey M Singh
Inadequacy of Headache Management After Subarachnoid Hemorrhage., Elizabeth K Glisic, Linda Gardiner, Linda Josti, Elizabeth Dermanelian, Sandra Ridel, John Dziodzio, Barbara McCrum, Ben Enos, Patricia Lerwick, Gilles L Fraser, Paul Muscat, Richard R Riker, Robert Ecker, Jeffrey Florman, and David B Seder
Pneumonia prevention in intubated patients given sucralfate versus proton-pump inhibitors and/or histamine II receptor blockers., Gene A Grindlinger, Sarah B Cairo, and Carole B Duperre
Free serum valproate concentration more reliable than total concentration in critically ill patients., Colman Hatton, Richard R. Riker, David J. Gagnon, Teresa May, David B. Seder, and Gilles L. Fraser
Closed mitral commissurotomy during pregnancy in East Africa., Robert Kramer, Reed Quinn, Agneta Odera, Robert Groom, Nancy Boulanger, Eric Gunnoe, and Russell White
Sedation quality in intensive care: which interventions work?, Richard R. Riker and Gilles L. Fraser
Early tracheostomy in ventilated stroke patients: Study protocol of the international multicentre randomized trial SETPOINT2 (Stroke-related Early Tracheostomy vs. Prolonged Orotracheal Intubation in Neurocritical care Trial 2)., Silvia Schönenberger, Wolf-Dirk Niesen, Hannah Fuhrer, Colleen Bauza, Christina Klose, Meinhard Kieser, José I Suarez, David B Seder, Julian Bösel, SETPOINT2-Study Group, and IGNITE-Study Group
The evolving paradigm of individualized postresuscitation care after cardiac arrest., David B Seder, Christine Lord, and David J Gagnon
Submissions from 2015
Recurrent human papillomavirus-related airway squamous cell carcinomas., Akshu Balwan, Hagen Blaszyk, and Thomas E Van der Kloot
SLEAP: a wake-up call to question the oversimplification of ICU delirium., Gilles L Fraser, David J Gagnon, and Richard R Riker
Prophylactic antibiotics are associated with a lower incidence of pneumonia in cardiac arrest survivors treated with targeted temperature management., David J Gagnon, Niklas Nielsen, Gilles L Fraser, Richard R Riker, John Dziodzio, Kjetil Sunde, Jan Hovdenes, Pascal Stammet, Hans Friberg, Sten Rubertsson, Michael Wanscher, and David B Seder
Etomidate in sepsis: understanding the dilemma., David J Gagnon and David B Seder
Association of gender to outcome after out-of-hospital cardiac arrest--a report from the International Cardiac Arrest Registry., Viktor Karlsson, Josef Dankiewicz, Niklas Nielsen, Karl B Kern, Michael R Mooney, Richard R Riker, Sten Rubertsson, David B Seder, Pascal Stammet, Kjetil Sunde, Eldar Søreide, Barbara T Unger, and Hans Friberg
Outcomes of comatose cardiac arrest survivors with and without ST-segment elevation myocardial infarction: importance of coronary angiography., Karl B Kern, Kapildeo Lotun, Nainesh Patel, Michael R Mooney, Ryan D Hollenbeck, John A McPherson, Paul W McMullan, Barbara Unger, Chiu-Hsieh Hsu, and David B Seder
Moderate-dose sedation and analgesia during targeted temperature management after cardiac arrest., Teresa L May, David B Seder, Gilles L Fraser, Philip Stone, Barbara McCrum, and Richard R Riker
Analgesia, sedation, and neuromuscular blockade during targeted temperature management after cardiac arrest., Richard R Riker, David J Gagnon, Teresa May, David B Seder, and Gilles L Fraser
Emergency neurological life support: airway, ventilation, and sedation., David B Seder, Andy Jagoda, and Becky Riggs
The authors reply., David B Seder, Richard R Riker, and Niklas Nielsen
Neurologic outcomes and postresuscitation care of patients with myoclonus following cardiac arrest., David B Seder, Kjetil Sunde, Sten Rubertsson, Michael Mooney, Pascal Stammet, Richard R Riker, Karl B Kern, Barbara Unger, Tobias Cronberg, John Dziodzio, and Niklas Nielsen
Submissions from 2014
Randomized ICU trials do not demonstrate an association between interventions that reduce delirium duration and short-term mortality: a systematic review and meta-analysis., Nada S Al-Qadheeb, Ethan M Balk, Gilles L Fraser, Yoanna Skrobik, Richard R Riker, John P Kress, Shawn Whitehead, and John W Devlin
Safety, feasibility, and outcomes of induced hypothermia therapy following in-hospital cardiac arrest-evaluation of a large prospective registry*., Josef Dankiewicz, Simon Schmidbauer, Niklas Nielsen, Karl B Kern, Michael R Mooney, Pascal Stammet, Richard R Riker, Sten Rubertsson, David Seder, Ondrej Smid, Kjetil Sunde, Eldar Søreide, Barbara T Unger, and Hans Friberg
Iron supplementation does not worsen respiratory health or alter the sputum microbiome in cystic fibrosis., Alex H Gifford, Diana M Alexandru, Zhigang Li, Dana B Dorman, Lisa A Moulton, Katherine E Price, Thomas H Hampton, Mitchell L Sogin, Jonathan B Zuckerman, H Worth Parker, Bruce A Stanton, and George A O'Toole
Early cardiac catheterization is associated with improved survival in comatose survivors of cardiac arrest without STEMI., Ryan D Hollenbeck, John A McPherson, Michael R Mooney, Barbara T Unger, Nainesh C Patel, Paul W McMullan, Chiu-Hsieh Hsu, David B Seder, and Karl B Kern
Clinical monitoring scales in acute brain injury: assessment of coma, pain, agitation, and delirium., Richard R Riker and Jennifer E Fugate
Prognosis after cardiac arrest: time to rethink why, how, and when*., David B Seder
Feasibility of bispectral index monitoring to guide early post-resuscitation cardiac arrest triage., David B Seder, John Dziodzio, Kahsi A Smith, Paige Hickey, Brittany Bolduc, Philip Stone, Teresa May, Barbara McCrum, Gilles L Fraser, and Richard R Riker
Geriatric experience following cardiac arrest at six interventional cardiology centers in the United States 2006-2011: interplay of age, do-not-resuscitate order, and outcomes., David B Seder, Nainesh Patel, John McPherson, Paul McMullan, Karl B Kern, Barbara Unger, Sudip Nanda, Melkon Hacobian, Michael B Kelley, Niklas Nielsen, John Dziodzio, and Michael Mooney
Submissions from 2013
Hyperperfusion syndrome after stent/coiling of a ruptured carotid bifurcation aneurysm., Robert D Ecker, Richard D Murray, and David B Seder
Voices of family members and significant others in the tele-intensive care unit, Mary Jahrsdoerfer and Susan Goran
Single-dose etomidate is not associated with increased mortality in ICU patients with sepsis: analysis of a large electronic ICU database., Laura C McPhee, Omar Badawi, Gilles L Fraser, Patricia A Lerwick, Richard R Riker, Ilene H Zuckerman, Christine Franey, and David B Seder
Submissions from 2011
A new view: tele-intensive care unit competencies, Susan F. Goran
Surface cooling after cardiac arrest: effectiveness, skin safety, and adverse events in routine clinical practice., Salam Jarrah, John Dziodzio, Christine Lord, Gilles L Fraser, Lee Lucas, Richard R Riker, and David B Seder
Submissions from 2009
Methods of cooling: practical aspects of therapeutic temperature management., David B Seder and Thomas E Van der Kloot
The patient care coordinator role: an innovative delivery model for transforming acute care and improving patient outcomes, Lois Napier Skillings and Deborah MacLeod