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Subarachnoid hemorrhage (SAH) is a severe type of stroke categorized by a sharp, sudden, and persistent headache. The mechanism of headache after SAH is currently poorly understood but the neuro-inflammatory response has been identified as a target in understanding the causes of headache after SAH. A better understanding of this mechanism may lead to identification of molecular targets for therapeutic reduction of headache pain and improving outcomes after SAH. In this study, we collected cerebrospinal fluid (CSF) from patients hospitalized with SAH and conducted a cytokine array to screen for soluble factors involved in SAH-associated headache Introduction
Glisic, Elizabeth; deKay, Joanne T.; Lerwick, Patricia; Gagnon, David J.; Riker, Richard; and Ryzhov, Sergey, "Cytokine CXCL2 concentration in the cerebrospinal fluid of patients with aneurysmal subarachnoid hemorrhage is associated with patient-reported headache pain" (2022). Costas T. Lambrew Research Retreat 2022. 26.