Lightening up a notch: notch regulation of energy metabolism.

Document Type

Article

Publication Date

8-1-2014

Institution/Department

Molecular Medicine

Journal Title

Nature medicine

MeSH Headings

Adipose Tissue, Brown, Adipose Tissue, White, Animals, Female, Immunoglobulin J Recombination Signal Sequence-Binding Protein, Male, Obesity, Receptor, Notch1

Abstract

Inhibiting Notch signaling induces adipose browning, improves systemic glucose tolerance and insulin sensitivity, and suppresses weight gain in mice.

ISSN

1546-170X

First Page

811

Last Page

812

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