Title

Lightening up a notch: notch regulation of energy metabolism.

Document Type

Article

Publication Date

8-1-2014

Institution/Department

Molecular Medicine

Journal Title

Nature medicine

MeSH Headings

Adipose Tissue, Brown, Adipose Tissue, White, Animals, Female, Immunoglobulin J Recombination Signal Sequence-Binding Protein, Male, Obesity, Receptor, Notch1

ISSN

1546-170X

Abstract

Inhibiting Notch signaling induces adipose browning, improves systemic glucose tolerance and insulin sensitivity, and suppresses weight gain in mice.

First Page

811

Last Page

812

Share

COinS