Incorporated in 1868, MMC is the state’s largest medical center, licensed for 700 beds and employing more than 9,600 people. MaineHealth Maine Medical Center’s unique role as both a community hospital and a referral center requires an unparalleled depth and breadth of services, including the state’s only allopathic medical school program, through a partnership with Tufts University School of Medicine, and a world-class biomedical research center, the MaineHealth Institute for Research.

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Submissions from 2026

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Thyroid hormone excess targeted to oxytocin neurons disrupts oxytocin physiology without impacting behavior, J Patrizia Stohn, Zhaofei Wu, and Arturo Hernandez

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New insights into the pathogenesis of osteoporosis and the translational approach to personalized therapy, Bolun Li, Linyi Liu, En Luo, Hanghang Liu, and Clifford J. Rosen

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Regional neurodevelopmental and psychosocial encounters for children with CHD: an updated validation cohort from Northern New England, Thomas Miller, Anya Cutler, Brooke Davey, and Jonathan Flyer

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Updates in Hospital Medicine: Oncology, Andrew C. Lyu, Madeleine Coleman, and Lesley B. Gordon

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Attainment of Substantial Clinical Benefit Following Primary Total Knee Arthroplasty Is Impacted by Preoperative Patient-Reported Outcome Measures, Catherine M. Call, Zoë A. Walsh, Johanna A. Mackenzie, George M. Babikian, Brian J. McGrory, and Adam J. Rana

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Implementing School-Associated Vaccination Events in Colorado Public Schools: A Statewide Survey of Nurses, Liliane Nienstedt, Ashley Gromis, Laura J. Faherty, and Ariella R. Korn

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What We Do Matters: A Documentary Style Video to Address Healthcare Stigma Toward People Who Use Substances, Andrea Truncali, Wendy Y. Craig, and Kristen Silvia

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Aging aggravates early scar healing after facial laceration through fibroblast-centered extracellular matrix remodeling, Hanghang Liu, Kangyao Hu, Jinbo Zhou, Xin Zhang, and Linyi Liu

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Test characteristics of cardiac point-of-care ultrasound in paediatric shock: insights from multisystem inflammatory syndrome in children, Bethsabee S. Stone, Kiyetta H. Alade, Stephanie K. Leung, Elizabeth A. Camp, and Alan F. Riley

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When a Major Orthopaedic Device Manufacturer Does Not Offer Replacement Components for Revision Surgeries, Brian J. McGrory, Samantha Blau, Melissa Graham, and Stephen Tower

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Lipid Cargo of Small Extracellular Vesicles as a Novel Contributor to Cardiovascular Diseases, Cameron Keene, Lacey Knudsen, Lucy Liaw, and Ilka M. Pinz

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A combination of aerobic and resistance training induces white adipose tissue browning, Caroline de Picoli, Gustavo Renan Gilio, Felipe Henriques, Kaltinaitis B. Santos, Magno Alves Lopes, and Solange Marta de Moraes

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Society for Vascular Surgery Vascular Quality Initiatives Contemporary Benchmarks: Varicose Vein Treatments, Cassius Iyad Ochoa Chaar, Nicholas Wells, Jennifer L. Ellis, Nicholas H. Osborne, Peter F. Lawrence, Thomas F. O'Donnell, and Jens Eldrup-Jorgensen

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Exosome trafficking is a key regulator of adipocyte thermogenesis, Devesh Kesharwani, Michele Karolak, Chad Doucette, Rachelle Mendola, Summer Pray, Raghu Bhardwaj, Su Su, Ann Harrington, and Victoria Demambro

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Endogenous Klebsiella pneumoniae Endophthalmitis With Iris Abscess and Discordant Systemic and Ocular Culture Susceptibilities, Ava Romerosa, Luke B. Farson, Nimesh Patel, and Jeffrey K. Moore

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The Use of High-dose Diazepam in Combination With ECT for Treatment of Pediatric Catatonia, Ellen Meierer, Matthew Nilsson, and Roslyn Gerwin

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Implications of GLP-1 receptor agonists for the fertility of women with polyendocrine metabolic ovarian syndrome, Pawel Kordowitzki, Anju E. Joham, and Clifford J. Rosen

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From frameworks to the frontline: Hospitalist perspectives on diagnostic excellence programs, Angela Keniston, Raymond M. Klein, Michael Tozier, Andrew Auerbach, Peter Barish, and Molly A. Kantor

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Beyond Direct Observation: Leveraging Ambient Listening AI for Scalable Communication Coaching, Rhianon R. Liu and Rebecca N. Hutchinson

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Artificial intelligence in emergency medicine education: A narrative review, Jessica Pelletier, Juan Pablo Arango-Ibanez, R Andrew Taylor, Moira E. Smith, Michael Gottlieb, Derick D. Jones, and Angelica Rego

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Association Between Initiation of Cardiac Rehabilitation after Hospitalization for Heart Failure and 1-Year Survival Among Medicare Beneficiaries, Tara Lagu, Aruna Priya, Kristen Lee, and Quinn R. Pack

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Evaluation of a Digital Clinician-Training Module for Treatment of Transgender and Gender Diverse Patients With Eating Disorders: Pre-Post Study, Nora Yanyi Sun and Alex S. Keuroghlian

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Preference Signaling in the General Surgery Residency Match: The Applicant Perspective, Alexa P. Bosco, Samantha Ahle, Kenneth Lynch, Ashlie Haas-Rodriguez, and Jaswin Sawhney MD

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SIRT1 promotes endothelial activity and osteogenesis in vitro and ameliorates age-related skeletal regeneration defects in vivo, Shibo Liu, Jingjing Shao, Qiheng Yang, and Hanghang Liu

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Clinical Guidance on the Safe Use of Sodium-Glucose Cotransporter Inhibitors in Adults with Type 1 Diabetes, Jayachidambaram Ambalavanan, Kanchan Bhasin, and Viral N. Shah

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Comparing Perceptions Sensitivity, Specificity and Practicality of PICO versus SPIDER questions in Nurse Residents’ Literature Searches, Hannah Taylor and Kate Campbell

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Consolidation Therapy Based on Mutation Clearance in Acute Myeloid Leukemia, Meagan A. Jacoby, David H. Spencer, Feng Gao, Geoffrey L. Uy, and Peter Westervelt

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Evaluate or ignore: National variation in the evaluation of adrenal lesions in over 250,000 patients, Jessica K. Hall, Joshua John Horns, Samantha Saperstein, Rupam Das, and Lauren Slattery

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From Chaos to Charge: A Workshop Series that Actually Works, Kate Campbell and Hannah Taylor

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Identifying Endocrinology Nurse Practitioners and Physician Associates Using Claims Data, Anya Cutler, Dana Schwartz, Chelsea Bodnar, Laura Faherty, and James Bohnhoff

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Superficial intercostal plane blocks for post-sternotomy pain control rationale and design for the EPOCH CardioLink-10 randomized clinical trial, Nitish K. Dhingra, Fallon Dennis, Syed Mohammad Hassan, Adrian Quan, Hwee Teoh, Kyle Chin, Michael J. Ricci, John D. Tran, and Ansar Hassan

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From promise to practice: digital health through the lens of neonatal care, Gabriel Fernando Variane, Danieli Mayumi Leandro, Marcelo Jenne Mimica, Topun Austin, Valerie Y. Chock, and Alexa Craig

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Patterns of Firearm Injury Across a Rural State: A 10-Year Single Center Experience, Lucero G. Paredes, Carolyne R. Falank, Bryan C. Morse, Julianne B. Ontengco, and Christopher G. Turner

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Omitting Bone Marrow Sampling in FDG-Avid Rhabdomyosarcoma With 2-[F]FDG PET-Negative Marrow: Results From an International Retrospective Study, Federico Mercolini, Marissa Just, Barry L. Shulkin, Natalie B. Collins, and Aaron R. Weiss

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Off-pump coronary artery bypass grafting in a patient with moyamoya syndrome: A case report and literature review, Cecilia E. Guadalupi, Robert D. Ecker, and Walter F. DeNino

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Comparing niraparib versus platinum-taxane doublet chemotherapy as neoadjuvant treatment in patients with newly diagnosed homologous recombination-deficient stage III/IV ovarian cancer: Findings from cohort C of the OPAL phase 2 trial, Shannon N. Westin, Jimmy Belotte, Brunella Felicetti, Vishvajit Aghera, and Bradford S. Leslie

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Early stratification of risk for poor neurological outcome after cardiac arrest is improved with processed EEG data, Qingchu Jin, Richard R. Riker, Teresa L. May, and Ghanahshyam Kshirsagar

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Perspectives of Simulated Patients Who Portray People Living With Serious Illness, a Qualitative Study, Laura T. Director, Christine Mallar, Martha S. Barbour, and Mary H. Becker

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Metabolic, viral, and immune phenotypes in long COVID, Ivette F. Emery, Seynt Jiro Sahagun, Elizabeth R. Zunica, Christopher Axelrod, and Clifford J. Rosen

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Duration of Therapeutic Hypothermia After Out-of-Hospital Cardiac Arrest: The ICECAP Randomized Clinical Trial, William J. Meurer, Sharon D. Yeatts, Romergryko G. Geocadin, Akash Roy, Clifton W. Callaway, Viswanathan Ramakrishnan, Scott M. Berry, Angela F. Caveney, and Teresa L. May

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Fecal microbiome transplant in food allergy in humans and mice identifies a role for bile acid metabolites in oral tolerance, Rima Rachid, Monica Martinez-Blanco, Gavin A. Kuziel, Emmanuel Stephen-Victor, Mathieu Groussin, Askarbek Orakov, and George Russell

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Rural-Urban Disparities in Contemporary Systemic Therapy for Advanced Prostate Cancer, Zhiyu Qian, Stephan Korn, Kerry L. Kilbridge, Brent K. Hollenbeck, and Alexander P. Cole

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Beneficiary Characteristics Associated With Volume of Skilled Clinical Nursing and Therapy Home Health, Zoe Samson, Lauren J. Hunt, Laura M. Wagner, and Ulrike Muench

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Enhanced Communication is Fundamental in Providing Quality Care, Jacqueline Turcotte RN, MSN, CCRN

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Landmark Versus Ultrasound-Guided Identification of the Cricothyroid Membrane: A Randomized, Prospective Trial, Megan Hoffer, Aditya Loganathan, Fatemeh W. Nasri, Jordan Dow, Margarita Popova, and Elizabeth Dearing

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Superficial parasternal intercostal plane block with ropivacaine versus placebo for opioid exposure after cardiac surgery (EPOCH CardioLink-10): a multicentre, double-blind, randomised trial, Ahmad Alli, C David Mazer, Fallon Dennis, Hwee Teoh, Kyle Chin, Adrian Quan, S M. Hassan, Michael Szarek, and Ansar Hassan

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Thiamine responsive lactic acidosis in patients not in shock: A case series and literature review, Will Jaffee, Kurt Grahnke, Alexander G. Tito, and Avery Pellnat

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Time to Treatment Initiation and Survival in Patients With Muscle-Invasive Bladder Cancer (MIBC), Andrea Piccolini, Marco Paciotti, Stephan M. Korn, Zhiyu Qian, Pietro Brin, Klara Pohl, and Alexander P. Cole

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Usability and Acceptability of a Symptom Checker App by Patients Seeking Urgent Care, Hamish S. Fraser, Ian Bacher, Ishaani Khatri, Sasha Raman, and Ross Hilliard

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Analgesic Efficacy and Safety of Intrathecal Morphine in Surgical Patients: A Narrative Review, Chloe P. Veilleux, Alison R. Omsberg, Janelle M. Richard, and Aurora N. Quaye

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Systemic involvement in rheumatic diseases, Rachel M. Wolfe and Kenneth S. O'Rourke

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Molecular Classification Predicts Clinical Outcomes of Kidney Transplant Recipients With Microvascular Inflammation, Donor-specific Antibodies-negative and C4d-negative, Fahad Aziz, Hao Zhang, Peale Chuang, Wenlan Tian, and Arjang Djamali

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Empiric Use of TXA in Geriatric Trauma is Not Associated With Blood Product Utilization, Survival, or VTE Incidence, Kristen M. Kelliher, Carolyne R. Falank, Peter Kyros, and Forest R. Sheppard

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Diagnostic reasoning with and without AI: automation bias in pre-clerkship medical students, Robert Hayden, Maria Blanco, Saradha Ramesh, and Scott Epstein

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Exercise Habits and BMI in Pediatric Patients with Anomalous Aortic Origin of Coronary Arteries, Thomas S. Przybycien, Dana Reaves-O'Neal, Kimberly Gray, Sandra Mihail, Tam T. Doan, Shagun Sachdeva, Ziyad M. Binsalamah, and Silvana Molossi

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Patient-and Caregiver-Centered Outcomes in Survivors of Severe Stroke with Respiratory Failure at 6 Months: A Substudy of the SETPOINT2 Trial, Matthew N. Jaffa, David B. Seder, Susanne Muehlschlegel, and Jan Meis

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When Cancer Care Moves Closer to Home: Closing the Psychosocial Gap in Community Oncology, Emily M. Sorg, Alexa H. Gips, Kelly E. Irwin, and Jamie M. Jacobs

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Supportive Technology Promotes Research Engagement Among Nurses and Allied Health Professionals, Rachael Haskell, Zoe Samson, Justin Peterson, and Kristiina Hyrkas

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Caecal volvulus around the mesentery of ileal neobladder: a case report, Chinedu Okoli, Andrew Eksi, and Damien Carter

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Fetal Anatomic and Physiologic Predictors of Neonatal Hypoxia in D-Transposition of the Great Arteries: A Prospective, Multi-Center Study by the Fetal Heart Society Research Collaborative, Joyce T. Johnson, David Schidlow, Jacqueline Shuplock, Mary T. Donofrio, Shaine A. Morris, Lisa K. Hornberger, and Thomas A. Miller

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In a Scrape: The Implications of Open Access AI Bot Scraping, Dina McKelvy MA, MLS

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A multi-institutional rapid qualitative assessment of factors supporting diagnostic excellence in hospital medicine, Katie E. Raffel, Chase J. Webber, Maya Narayanan, Michael Tozier, Matthew Cerasale, and Tiffany M. Lee

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Using Electronic Health Records to Enhance Lyme Disease Surveillance: Protocol for the SubLyme Network, Annemarie G. Hirsch, Brian S. Schwartz, Melissa N. Poulsen, Anna M. Schotthoefer, Maria E. Sundaram, Jacob E. Lemieux, and Robert P. Smith

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Informal peer diagnostic second opinion: Hospitalist practices and perspectives, Taiju Miyagami, Andrew Auerbach, Jeffrey L. Schnipper, Sumant Ranji, Peter Barish, Molly A. Kantor, and Raymond M. Klein

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Cerebrovascular reactivity in migraine: a breath-hold BOLD fMRI study, Adam S. Sprouse Blum, Richard Watts, Scott G. Hipko, Jay V. Gonyea, Anna E. Senft-Miller, Olivia K. Nop, and James B. Allison

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Birth Weight Percentiles and Infant and Child Growth Dynamics, María Alejandra Hernandez, Richard M. Parker, Tim J. Cole, Izzuddin M. Aris, Henrique Barros, Johan G. Eriksson, and Abby F. Fleisch

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Central Venous Catheter Selection, Management, and Treatment of Catheter-Associated Deep Vein Thrombosis in Children Undergoing Cardiac Surgery: A Survey of Pediatric Cardiac Critical Care Consortium Centers, John S. Kim, Jason T. Patregnani, Ashish A. Ankola, Kurt Schumacher, Darren Klugman, Therese M. Giglia, Sirine A. Baltagi, and Jennifer G. Baylor

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Documentation of Psychosis Risk Screening in Same-Day Adolescent Behavioural Health Consultations, Julia A. Plumb, Kelsey A. Johnson, Cailin Ryrie, Kristen A. Woodberry, and Lydia A. Shrier

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Escape Room vs. Classroom: A Comparative Study on Meaningful Learning and Knowledge Retention, Michael DeFrancisco, Amanda Bennett, and Victoria English

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Intracranial Atherosclerotic Disease Distribution Across Circle of Willis Segments: Insights from CREST-H, Pranjal Rai, John Huston, Thomas G. Brott, Lloyd Edwards, George Howard, Ronald Lazar, and Robert D. Brown Jr

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Nutrition and Culinary Education in Food Is Medicine Interventions: A Scoping Review, Lizbeth Moreno Loaeza, Ronit Ridberg, Sydney Yearley, Julia R. Sharib, Narmeen Rehman, Francesca Piccolo, Fang Fang Zhang, and Dariush Mozaffarian

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Results of the American Venous Forum research retreat on C2 disease confirms that the biology of varicose veins including etiology, progression, and novel therapeutics, as well as disparities, are top research priorities, Ulka Sachdev-Ost, Andrea Obi, Eri Fukaya, Cassius Ochoa Chaar, Scott Robinson, Limael Rodriquez, Khan Nguyen, Peter Henke, and Andre Van Rij

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Rethinking Lactate in Cardiac Surgery and Intensive Care, John Guzzi, Ryan Salter, Stephen Pettit, Tyler Kelting, Florian Falter, and Albert C. Perrino

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Synthesis of Protocols for Frostbite Care from the FROST Study Sites, Rachel M. Nygaard, Emily Colonna, Alexander Poole, Lee D. Faucher, Rosemary E. Paine, and Naveen Sangji

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Updates in Hospital Medicine: Anticoagulation, Anastasia M. Tsomides, Wesley R. Zemrak, and Lesley B. Gordon

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An Idiographic, Mixed Methods Approach to Understanding Adolescent-Dog Relationships in the Context of Social Anxiety, Megan K. Mueller, Jasmine Mote, Eric Anderson, and Brianna Paquette

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Outcome of metastatic non-rhabdomyosarcoma soft tissue sarcoma in children and young adults treated on children's oncology group ARST0332 trial, Sapna Oberoi, Zhengya Gao, Wei Xue, Robert L. Randall, Cheryl M. Coffin, Lynn Million, and Aaron R. Weiss

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Insights From the First Year of Program Signaling in Cardiovascular Disease Fellowship Recruitment, Victor Soukoulis, Maxwell E. Afari, Zain U. Abideen Asad, Dipanjan Banerjee, Aniruddha Singh, and Pritha Subramanyam

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Looking beyond the frame: Storytelling, identity, and the illness narrative., Anna Maria Gramelspacher and Sam Woodworth MD

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Proteomics reveal PTEN as a critical mediator of sustained mitochondrial dysfunction during chronic spinal cord injury, Samir P. Patel, Carlos A. Gartner, Mudjgiwa Patience, Jaydeepbhai Patel, Victoria K. Slone, Dylan E. Capes, Krithika Iyer, and Maria F. Zapata-Jaramillo

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Artificial Intelligence in Urology: A Review of United States Food and Drug Administration-Cleared Devices, Zhiyu Qian, Pietro Brin, Stephan Korn, Andrea Cosenza, Hanna Zurl, and Alexander P. Cole

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Comparative Efficacy of Continuous Versus Patch ECG Monitoring in Detecting Atrial Fibrillation Recurrence Post Catheter Ablation: Insights From the REAL-AF Registry, Chinmaya Mareddy, Yashendra Sethi, Gurpreet Johal, Manasvi Gupta, Joshua Silverstein, Amit Thosani, Paul Zei, Linda Justice, and Jordan L. Mange

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Platelet FcɣRIIa Expression Refines Clinical Risk Assessment After Myocardial Infarction, David J. Schneider, Sean R. McMahon, Dominick J. Angiolillo, Alexander C. Fanaroff, Homam Ibrahim, Patrick K. Hohl, Brett L. Wanamaker, and Mark B. Effron

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Corrigendum to "American Association of Clinical Endocrinology Consensus Statement: Algorithm for Management of Adults With Type 2 Diabetes - 2026 Update" [Endocrine Practice. 2026;32(4):473-518], Susan L. Samson, Priyathama Vellanki, Lawrence Blonde, Irl B. Hirsch, Thanh D. Hoang, Scott D. Isaacs, Kenneth E. Izuora, Cecilia C. Low Wang, and Christine L. Twining

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Delays in diagnosis and treatment of depressive disorder among young adults: A national online survey-based cross-sectional study, Rena Xu, David Pletta, Caitlynn Feng, Cassandra Morrow, Maya C. Clark, Badar Omar, Alex S. Keuroghlian, and Sari L. Reisner

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Diagnosing helminth infections in a large reference laboratory in the United States: a 6-month pre- and post-implementation analysis of AI-augmented screening of concentrated fecal wet mounts, Cole P. Anderson, Marc Roger Couturier, Mark DeMaranville, Ryan Jensen, Madison Sant, Adam Barker, and Blaine A. Mathison

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Using Early and Periodic Screening, Diagnostic, and Treatment (EPSDT) to improve access to obesity pharmacotherapy: A practical guide for clinicians caring for youth with obesity across United States Medicaid programs: : Using EPSDT to Improve Access to Obesity Pharmacotherapy, Jaime M. Moore, Valerie M. O'Hara, Cassie Totman, Brooke Sweeney, Sarah Hampl, and Alaina P. Vidmar

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The periosteum as an endocrine organ: historical foundations and new insights, Madhura Nijsure and Clifford J. Rosen

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Feasibility and acceptability of a rural palliative care intervention for patients with heart failure (RuPAL-HF), Francesca X. Piccolo, Eric C. Anderson, Hanna Gutow, Claire M. Johnson, Michelle D. Nevers, Susan DeSanto-Madeya, and Rebecca N. Hutchinson

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Predictors of Serum Per- and Polyfluoroalkyl Substances (PFAS) Concentrations in a Rural Agricultural Community Affected by Biosolids Application, Lisa B. Rokoff, Katherine Senechal, Megan E. Romano, Julianne Cook Botelho, Antonia M. Calafat, Rachel Criswell, and Abby F. Fleisch

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Missed outpatient appointments: Who's missing out and Why?, Emma A Harwood, Daniel Lassman, Evelyn James, Bruce Ndebanje, Ethan Griffin, and Lily C Wang

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Donor-Specific Transplant Outcomes from BMTCTN 1702: A Multi-Center Prospective Biological-Assignment Trial, Asad Bashey, Brent R. Logan, LaQuisa C. Hill, Heather J. Symons, Nosha Farhadfar, Michael R. Grunwald, Joseph A. Pidala, Jason G. Dehn, and Peter Westervelt

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Antibiotic stewardship in hospital outpatient departments: a qualitative study of alignment with existing guidance, Salome O. Chitavi, Whitney R. Buckel, Michael Kohut, Barbara Braun, Rachel Zetts, and David Hyun

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Convalescent Spontaneous Coronary Artery Dissection With Elevated Pericoronary Fat Attenuation Index, Alec L. Sinatro, Thomas J. Nero, and Sharonne N. Hayes

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Emergency Department-initiated standard versus high-dose buprenorphine induction (ENVISION): a randomised clinical trial protocol, Kathryn Hawk, Andrew Herring, Marek Chawarski, Erik S. Anderson, Michael Baumann, Alyrene Dorey, August F. Holtyn, and Christopher Jones

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Longitudinal Telesimulation Program and Rural Clinicians' Neonatal Resuscitation Performance, Misty Melendi, Allison Zanno, Sophie Martens, Anya Cutler, Micheline Chipman, Leah Marie Seften, Tara Palnitkar, Mary Ottolini, and Leah Mallory

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Mobile Phone Auscultation to Diagnose Influenza A in Patients Presenting to Three Different Emergency Departments, Caroline Emily Gosser, Martin Huecker, Haely Studebaker, Jarred Jeremy Thomas, Craig Ziegler, and Ryan M. Close

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Advancing Patient Centered Care Through Integration of the ICU Liberation Flowsheet in the Electronic Medical Record to Improve Spontaneous Awakening Trial Compliance in the ICU, Amy Stafford

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Baseline serum metabolites predict fractures in individuals who were Black and had type 2 diabetes., Carolyn Chlebek, Valerie Bussberg, Niven R Narain, Michael A Kiebish, Yu-Hua Tseng, Clifford J Rosen, and Matthew D Lynes

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Benefits and risks of therapeutic hypothermia for hypoxic-ischemic encephalopathy in late preterm infants, Mohamed El-Dib, Dalal Abdelgadir, Kaashif A. Ahmad, Mariam Ayed, Jennifer Burnsed, Raul Chavez-Valdez, Mehmet N. Cizmeci, Alexa Craig, and Floris Groenendaal