Comparison of a pediatric-specific and an institution-wide antibiogram

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Child, Humans, Microbial Sensitivity Tests, Health Facilities


Objectives: Many pediatric hospitals within larger institutions have cumulative antibiograms combining pediatric and adult pathogen susceptibilities, although resistance patterns may vary between these populations. The purpose of this study is to determine if differences exist in susceptibility patterns between a pediatric-specific and an institution-wide antibiogram at Maine Medical Center (MMC). Methods: Susceptibility rates for all isolates from patients <18 years collected between January 1 and December 31, 2012 will be gathered and compared to the 2012 institution-wide antibiogram at Maine Medical Center utilizing Chi-square analysis. Results: Based on preliminary data, S. aureus was more susceptible to oxacillin (77% vs. 68%) in the pediatric vs. the institution-wide population. For E.coli, the pediatric population was also more susceptible to ciprofloxacin (94% vs. 82%) and levofloxacin (95% vs. 84%) than the hospital-wide population. Alternatively, for P. aeruginosa, the pediatric population compared to the hospital-wide population was less susceptible to aztreonam (65% vs. 74%), cefepime (75% vs. 90%), imipenem (80% vs. 88%), meropenem (82% vs. 91%), piperacillin/tazobactam (80% vs. 92%), and tobramycin (80% vs. 89%), respectively. The final pediatric antibiogram is underway and detailed analysis of the antibiogram will be completed by the end of February. Conclusion: Preliminary results suggest differences exist in susceptibility between the pediatric-specific and institution-wide antibiograms at MMC. Providing a pediatric-specific antibiogram could help guide selection of appropriate empiric therapy and improve patient outcomes.


Conference: 2014 American College of Clinical Pharmacy Virtual Poster Symposium

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