IOM committee members respond to Endocrine Society vitamin D guideline.

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Publication Date



Maine Medical Center Research Institute

Journal Title

The Journal of clinical endocrinology and metabolism

MeSH Headings

25-Hydroxyvitamin D 2, Age Factors, Calcifediol, Calcium, Dietary, Endocrinology, Female, Health Promotion, Humans, Intestinal Absorption, Lactation, Male, National Academies of Science, Engineering, and Medicine, U.S., Health and Medicine Division, Nutritional Requirements, Parathyroid Hormone, Practice Guidelines as Topic, Pregnancy, Societies, Scientific, United States, Vitamin D, Vitamin D Deficiency


In early 2011, a committee convened by the Institute of Medicine issued a report on the Dietary Reference Intakes for calcium and vitamin D. The Endocrine Society Task Force in July 2011 published a guideline for the evaluation, treatment, and prevention of vitamin D deficiency. Although these reports are intended for different purposes, the disagreements concerning the nature of the available data and the resulting conclusions have caused confusion for clinicians, researchers, and the public. In this commentary, members of the Institute of Medicine committee respond to aspects of The Endocrine Society guideline that are not well supported and in need of reconsideration. These concerns focus on target serum 25-hydroxyvitamin D levels, the definition of vitamin D deficiency, and the question of who constitutes a population at risk vs. the general population.



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