Sexual Orientation and Age at Menarche in Three U.S. Longitudinal Cohorts
The Journal of adolescent health : official publication of the Society for Adolescent Medicine
Bisexuality; Female; Heterosexuality; Humans; Longitudinal Studies; Male; Menarche; Sexual Behavior; Sexual and Gender Minorities
PURPOSE: The aim of this study is to examine age at menarche across sexual orientation groups. METHODS: Data were obtained from 131,090 female participants, born 1947-2001, in 3 longitudinal studies-the Growing Up Today Study and Nurses' Health Study 2 and 3. We estimated the association between sexual orientation and age at menarche using regression models adjusted for age, race/ethnicity, birthweight, height, and body mass index. RESULTS: Compared to heterosexual participants, sexual minorities were younger at menarche. Sexual minorities were more likely to have early menarche (≤11 years) and less likely to have late menarche (≥14 years) compared to heterosexual girls. As an example of this pattern, Nurses' Health Study 3 bisexual participants were >30% more likely than heterosexuals to have early versus average menarche (odds ratio 1.37, 95% confidence interval 1.09-1.72). CONCLUSION: Sexual minority girls have a younger age at menarche than heterosexual girls and may benefit from screening for adverse outcomes associated with early menarche.
Charlton BM, Carwile JL, Chavarro JE, DiVasta AD, Ziyadeh NJ, Austin SB. Sexual Orientation and Age at Menarche in Three U.S. Longitudinal Cohorts. J Adolesc Health. 2022;70(1):163-166. doi:10.1016/j.jadohealth.2021.06.029