Methods of cooling: practical aspects of therapeutic temperature management.

Document Type


Publication Date



Critical Care Medicine

Journal Title

Critical care medicine

MeSH Headings

Algorithms, Body Temperature Regulation, Brain Injuries, Cerebrovascular Circulation, Clinical Protocols, Conscious Sedation, Critical Care, Decision Trees, Energy Metabolism, Heart Arrest, Humans, Hypothermia, Induced, Intubation, Intratracheal, Monitoring, Physiologic, Patient Selection, Seizures, Severity of Illness Index, Shivering


OBJECTIVES: To review traditional and newer means of inducing, maintaining, and withdrawing therapeutic hypothermia and normothermia. To suggest treatment algorithms for temperature modulation and review neuromonitoring options.

DESIGN: A review of current literature describing methods of performing therapeutic temperature management and neuromonitoring during the cooling, maintenance, and decooling periods. Algorithms for performing therapeutic temperature management are suggested.

RESULTS: Temperature management can be safely and effectively performed using traditional or newer modalities. Although traditional means of cooling are feasible and efficacious, modern devices utilizing feedback loops to maintain steady body temperature and prevent overcooling have advantages in ease of application, patient safety, maintenance of target temperature, and control of decooling. Neuromonitoring options should be adapted to an individual patient and situation.

CONCLUSIONS: Intensivists should be familiar with techniques to induce, maintain, and withdraw therapeutic temperature management, and select the most appropriate method for a given patient and situation.




First Page


Last Page