Title

Clinical and research considerations for patients with hypertensive acute heart failure: a consensus statement from the Society for Academic Emergency Medicine and the Heart Failure Society of America Acute Heart Failure Working Group.

Document Type

Article

Publication Date

8-2016

Institution/Department

Critical Care

Journal Title

Academic emergency medicine : official journal of the Society for Academic Emergency Medicine

MeSH Headings

Acute Disease, Advisory Committees, Aged, Biomedical Research, Consensus, Diuretics, Dose-Response Relationship, Drug, Emergency Medicine, Emergency Service, Hospital, Female, Heart Failure, Humans, Hypertension, Male, Societies, Medical

ISSN

1553-2712

Abstract

Management approaches for patients in the emergency department (ED) who present with acute heart failure (AHF) have largely focused on intravenous diuretics. Yet, the primary pathophysiologic derangement underlying AHF in many patients is not solely volume overload. Patients with hypertensive AHF (H-AHF) represent a clinical phenotype with distinct pathophysiologic mechanisms that result in elevated ventricular filling pressures. To optimize treatment response and minimize adverse events in this subgroup, we propose that clinical management be tailored to a conceptual model of disease that is based on these mechanisms. This consensus statement reviews the relevant pathophysiology, clinical characteristics, approach to therapy, and considerations for clinical trials in ED patients with H-AHF.

First Page

922

Last Page

931

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