An appraisal of pharmacotherapy-pertinent literature published in 2023 and 2024 for clinicians caring for patients with thermal or inhalation injury

Lorraine A. Todor, Department of Pharmacy, University of Florida Health, Gainesville, FL, United States, 32608.
Allison N. Boyd, Department of Pharmacy, Eskenazi Health, Indianapolis, IN, United States, 46202.
Melissa Reger, Department of Pharmacy, Community Regional Medical Center, Fresno, CA, United States, 93721.
Akshara Patel, Department of Pharmacy, University of Florida Health, Gainesville, FL, United States, 32608.
Nasar Ansari, Department of Pharmacy, Grady Memorial Hospital, Atlanta, GA, United States, 30303.
Nicolas Tran, Department of Pharmacy, Tampa General Hospital, Tampa, FL, United States, 33606.
Janie Faris, Department of Pharmacy, Parkland Health, Dallas, TX, United States, 75325.
Asia N. Quan, Department of Pharmacy, Valleywise Health, Phoenix, AZ, United States, 85008.
C Joseph Kramer, Department of Pharmacy, University of Chicago Medicine, Chicago, IL, United States, 60637.
Todd A. Walroth, Department of Pharmacy, Eskenazi Health, Indianapolis, IN, United States, 46202.
Shannon Kuhrau, Department of Pharmacy, Loyola University Medical Center, Maywood, IL, United States, 60153.
Scott W. Mueller, Department of Pharmacy, University of Colorado Health, Aurora, CO, United States.
Beatrice Adams, Department of Pharmacy, Tampa General Hospital, Tampa, FL, United States, 33606.
Felix Pham, Department of Pharmacy, Torrance Memorial Medical Center, Torrance, CA, United States, 90505.
Kaitlin M. Alexander, Department of Pharmacotherapy and Translational Research, University of Florida College of Pharmacy, Gainesville, FL, United States, 32608.
Kathryn E. Smith, Department of Pharmacy, Maine Medical Center, Portland, ME, United States, 04102.
Kaylee M. Maynard, Department of Pharmacy, University of Rochester Medical Center, Rochester, NY, United States, 14620.
Alexandra DeWitt, Department of Pharmacy, University Medical Center New Orleans, New Orleans, LA, United States, 70112.
Lisa Smith, Department of Pharmacy, Doctors Hospital of Augusta, Augusta, GA, United States, 30809.
Nataša Stevković-Rašeta, Department of Pharmacy, John H. Stroger Jr. Hospital of Cook County, Chicago, IL, United States 60612.
Nicole M. Moreno, Department of Pharmacy, Mercy Hospital Springfield, Springfield, MO, United States 65806.
Sarah Cogle, Department of Pharmacy, Vanderbilt University Medical Center, Nashville, TN, United States, 37235.
David W. Gutenschwager, Department of Pharmacy, Bronson Methodist Hospital, Kalamazoo, MI, United States, 49007.
Vanessa Gleason, Department of Pharmacy, Thomas Jefferson University Hospital, Philadelphia PA 19107.
David M. Hill, Department of Pharmacy, Regional One Health, Memphis, TN, United States, 38103.

Abstract

Pharmacotherapy interventions following thermal or inhalation injury remain an underrepresented area of focus in the literature, with studies dispersed across a broad array of journals. This review builds upon several years of previous efforts to highlight and summarize the most recent, quality pharmacotherapy-focused studies in the context of thermal and inhalation injuries. Twenty-five geographically dispersed, board-certified pharmacists participated in the review. A MeSH-based, filtered search resulted in 2234 manuscripts over the previous 2-year period. After manual review, 78 (3.5%) manuscripts were determined to have a potential impact on current pharmacotherapy practice. Summaries of the 10 articles scored to have the highest impact are included in this review. There exists a continued need for high-impact research addressing pharmacotherapeutic strategies in the management of patients with thermal and inhalation injuries.