Title

Hungry bone syndrome two weeks after starting cinacalcet: a call for caution.

Document Type

Article

Publication Date

5-1-2018

Institution/Department

Nephrology, Internal Medicine

Journal Title

CEN case reports

ISSN

2192-4449

Abstract

Cinacalcet is an effective and safe alternative to parathyroidectomy in end stage renal disease (ESRD) patients with secondary hyperparathyroidism. Hypocalcemia is a known complication of treatment that is usually readily reversible upon discontinuation of the drug. It rarely manifests severely and symptomatically requiring hospital admission. We present the case of a 55 year old man with severe, symptomatic and prolonged hypocalcemia that occurred 2 weeks after starting cinacalcet. Cinacalcet induced a state of pharmacological parathyroidectomy with subsequent hungry bone syndrome. Serum calcium returned to normal range after 4 weeks of stopping the drug while receiving high doses of elemental calcium and vitamin D receptor activation therapy (VDRA).

First Page

21

Last Page

23

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