Document Type

Patent

Publication Date

4-26-2007

Patent Number

8173613

Abstract

The present invention relates to compositions and methods for the modulation of metastatic and mesenchymal cell growth and mobility via the regulation of the formation of Twist/Twist homodimers and Twist/E heterodimers. The present invention also relates to methods for screening agents and compound libraries for molecules that function to modulate the formation of Twist/Twist homodimers, Twist/E protein heterodimers or their upstream or downstream effector molecules.

Application Number

11525715

Institution/Department

Maine Medical Center

Assignees

Maine Medical Center

Filing Date

09/22/2006

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