Three Thyroid Hormone Stories: On Injury Response, Congenital Defects and Neurodevelopmental and Endocrine Disease

Authors

Arturo Hernandez PhD, Center for Molecular Medicine, MaineHealth Institute for Research, MaineHealth, Scarborough, ME, United States.Follow

Files

Institution/Department

Maine Medical Center

Publication Date

1-15-2025

Publisher

MaineHealth

City

Portland, Maine

Disciplines

Endocrinology, Diabetes, and Metabolism

Comments

Objectives:

Describe the basic mechanisms of thyroid hormone metabolism and action

Explain what is the euthyroid sick syndrome and understand the unanswered questions about its clinical relevance and physiological basis

Discuss the potential limitations of current standard treatments for Graves' disease during pregnancy to prevent congenital defects

Appreciate the large gaps in our understanding of the etiology of high prevalence, complex neurological and endocrine diseases, and the potential roles of developmental programming and non-genetic inheritance.

Recommended Citation

Hernandez, Arturo PhD, "Three Thyroid Hormone Stories: On Injury Response, Congenital Defects and Neurodevelopmental and Endocrine Disease" (2025). Department of Medicine Grand Rounds. 34.
https://knowledgeconnection.mainehealth.org/medicine_gr/34