Regulation of Skeletal Homeostasis.
Document Type
Article
Publication Date
10-1-2018
Institution/Department
Maine Medical Center Research Institute
Journal Title
Endocrine reviews
MeSH Headings
Animals, Bone Remodeling, Bone and Bones, Homeostasis, Humans
Abstract
Landmark advances in skeletal biology have arisen mainly from the identification of disease-causing mutations and the advent of rapid and selective gene-targeting technologies to phenocopy human disease in mice. Here, we discuss work on newly identified mechanisms controlling the remodeling of bone, communication of bone cells with cells of other lineages, and crosstalk between bone and vital organs as these relate to the therapeutic targeting of the skeleton.
ISSN
1945-7189
First Page
701
Last Page
718
Recommended Citation
Zaidi, Mone; Yuen, Tony; Sun, Li; and Rosen, Clifford J, "Regulation of Skeletal Homeostasis." (2018). MaineHealth Maine Medical Center. 1350.
https://knowledgeconnection.mainehealth.org/mmc/1350