Chronic Kidney Disease Is Associated With Greater Bone Marrow Adiposity.
Document Type
Article
Publication Date
12-1-2018
Institution/Department
Maine Medical Center Research Institute
Journal Title
Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research
MeSH Headings
Adipose Tissue, Adiposity, Aged, 80 and over, Bone Marrow, Female, Glomerular Filtration Rate, Humans, Male, Renal Insufficiency, Chronic
Abstract
Bone marrow adiposity is associated with aging, osteoporosis, and reduced hematopoiesis, as well as anorexia nervosa, but little is known about the underlying mechanisms that affect marrow adiposity. Chronic kidney disease (CKD) may influence bone marrow adipose tissue (BMAT), possibly through loss of lean mass or higher circulating levels of sclerostin. To test these hypotheses, we investigated the cross-sectional association between estimated glomerular filtration rate (eGFR) as a measure of kidney function and
ISSN
1523-4681
First Page
2158
Last Page
2164
Recommended Citation
Woods, Gina N; Ewing, Susan K; Sigurdsson, Sigurdur; Kado, Deborah M; Ix, Joachim H; Hue, Trisha F; Eiriksdottir, Gudny; Xu, Kaipin; Gudnason, Vilmundur; Lang, Thomas F; Vittinghoff, Eric; Harris, Tamara B; Rosen, Clifford J; Li, Xiaojuan; and Schwartz, Ann V, "Chronic Kidney Disease Is Associated With Greater Bone Marrow Adiposity." (2018). Maine Medical Center. 1545.
https://knowledgeconnection.mainehealth.org/mmc/1545
