The RNA demethylase FTO is required for maintenance of bone mass and functions to protect osteoblasts from genotoxic damage.
Document Type
Article
Publication Date
9-3-2019
Institution/Department
Center for Molecular Medicine, Maine Medical Center Research Institute
Journal Title
Proceedings of the National Academy of Sciences of the United States of America
MeSH Headings
Alpha-Ketoglutarate-Dependent Dioxygenase FTO, Animals, Apoptosis, Bone and Bones, DNA Damage, Dietary Fats, HSP70 Heat-Shock Proteins, Hydrogen Peroxide, Mice, Mice, Knockout, NF-kappa B, Osteoblasts, Signal Transduction, Stress, Physiological, Ultraviolet Rays
Abstract
The fat mass and obesity-associated gene (
ISSN
1091-6490
First Page
17980
Last Page
17989
Recommended Citation
Zhang, Qian; Riddle, Ryan C; Yang, Qian; Rosen, Clifford R; Guttridge, Denis C; Dirckx, Naomi; Faugere, Marie-Claude; Farber, Charles R; and Clemens, Thomas L, "The RNA demethylase FTO is required for maintenance of bone mass and functions to protect osteoblasts from genotoxic damage." (2019). Maine Medical Center. 1798.
https://knowledgeconnection.mainehealth.org/mmc/1798
