The RNA demethylase FTO is required for maintenance of bone mass and functions to protect osteoblasts from genotoxic damage.
Center for Molecular Medicine, Maine Medical Center Research Institute
Proceedings of the National Academy of Sciences of the United States of America
Alpha-Ketoglutarate-Dependent Dioxygenase FTO, Animals, Apoptosis, Bone and Bones, DNA Damage, Dietary Fats, HSP70 Heat-Shock Proteins, Hydrogen Peroxide, Mice, Mice, Knockout, NF-kappa B, Osteoblasts, Signal Transduction, Stress, Physiological, Ultraviolet Rays
The fat mass and obesity-associated gene (
Zhang, Qian; Riddle, Ryan C; Yang, Qian; Rosen, Clifford R; Guttridge, Denis C; Dirckx, Naomi; Faugere, Marie-Claude; Farber, Charles R; and Clemens, Thomas L, "The RNA demethylase FTO is required for maintenance of bone mass and functions to protect osteoblasts from genotoxic damage." (2019). Maine Medical Center. 1798.