Prospective Comparison of PET Imaging with PSMA-Targeted

Authors

Steven P Rowe
Xin Li
Bruce J Trock
Rudolf A Werner
Sarah Frey
Michael DiGianvittorio, Maine Medical CenterFollow
J Keith Bleiler
Diane K Reyes
Rehab Abdallah
Kenneth J Pienta
Michael A Gorin
Martin G Pomper

Document Type

Article

Publication Date

2-2020

Institution/Department

Radiology

Journal Title

Journal of Nuclear Medicine : Official Publication, Society of Nuclear Medicine

MeSH Headings

Antigens, Surface, Bone Neoplasms, Fluorine Radioisotopes, Glutamate Carboxypeptidase II, Humans, Lysine, Male, Positron Emission Tomography Computed Tomography, Prospective Studies, Prostatic Neoplasms, Sodium Fluoride, Urea

Abstract

Bone metastases in prostate cancer (PCa) have important prognostic significance, and imaging modalities used for PCa staging should have high sensitivity for detecting such lesions. Prostate-specific membrane antigen (PSMA)-targeted PET radiotracers are promising new agents for imaging PCa. We undertook a head-to-head comparison of PSMA-targeted 2-(3-{1-carboxy-5-[(6-

ISSN

1535-5667

First Page

183

Last Page

188

Recommended Citation

Rowe SP, Li X, Trock BJ, et al. Prospective Comparison of PET Imaging with PSMA-Targeted 18F-DCFPyL Versus Na18F for Bone Lesion Detection in Patients with Metastatic Prostate Cancer. J Nucl Med. 2020;61(2):183-188. doi:10.2967/jnumed.119.227793