Bone morphogenetic protein signaling in nephron progenitor cells.

Authors

Leif Oxburgh, Maine Medical Center
Aaron C. BrownFollow
Sree Deepthi Muthukrishnan
Jennifer L. Fetting

Document Type

Article

Publication Date

4-2014

Institution/Department

MMCRI; Molecular Medicine

Journal Title

Pediatric nephrology (Berlin, Germany)

MeSH Headings

Animals, Bone Morphogenetic Proteins, Humans, Nephrons, Organogenesis, Signal Transduction, Stem Cells

Abstract

Bone morphogenetic protein (BMP) signaling plays an essential role in many aspects of kidney development, and is a major determinant of outcome in kidney injury. BMP treatment is also an essential component of protocols for differentiation of nephron progenitors from pluripotent stem cells. This review discusses the role of BMP signaling to nephron progenitor cells in each of these contexts.

ISSN

1432-198X

First Page

531

Last Page

536

Recommended Citation

Oxburgh, Leif; Brown, Aaron C.; Muthukrishnan, Sree Deepthi; and Fetting, Jennifer L., "Bone morphogenetic protein signaling in nephron progenitor cells." (2014). MaineHealth Maine Medical Center. 348.
https://knowledgeconnection.mainehealth.org/mmc/348