Bone morphogenetic protein signaling in nephron progenitor cells.
MMCRI, Molecular Medicine
Pediatric nephrology (Berlin, Germany)
Animals, Bone Morphogenetic Proteins, Humans, Nephrons, Organogenesis, Signal Transduction, Stem Cells
Bone morphogenetic protein (BMP) signaling plays an essential role in many aspects of kidney development, and is a major determinant of outcome in kidney injury. BMP treatment is also an essential component of protocols for differentiation of nephron progenitors from pluripotent stem cells. This review discusses the role of BMP signaling to nephron progenitor cells in each of these contexts.
Oxburgh, Leif; Brown, Aaron C.; Muthukrishnan, Sree Deepthi; and Fetting, Jennifer L., "Bone morphogenetic protein signaling in nephron progenitor cells." (2014). Maine Medical Center. 348.