Next-gen tools in cancer neuroscience.
Document Type
Article
Publication Date
9-23-2025
Institution/Department
Center for Molecular Medicine
Journal Title
Cell Rep
MeSH Headings
Animals, Humans, Neurosciences, Neoplasms, Optogenetics, Mice
Abstract
The emerging field of cancer neuroscience is rapidly evolving, driven by novel technologies and tools. These include advances in single-cell and spatial transcriptomics; genetic mouse models paired with automated high-throughput; and innovative optical electrophysiological approaches, optogenetics, chemogenetics, engineered viruses, and new methods for visualizing neuronal activity. Collectively, these technologies are revolutionizing how we investigate, manipulate, and characterize distinct components that contribute to the nervous system-cancer interface. In the present review, we discuss the key technologies that are closing the gap between oncology and neuroscience, highlighting the innovations that are propelling the cancer neuroscience field forward.
ISSN
2211-1247
First Page
116258
Last Page
116258
Recommended Citation
Thiel, Vera; Sur, Debpali; Picoli, Caroline C; McErlain, Tamara; and Couto, Katalina, "Next-gen tools in cancer neuroscience." (2025). MaineHealth Maine Medical Center. 4184.
https://knowledgeconnection.mainehealth.org/mmc/4184
