Lyme Disease

Document Type

Article

Publication Date

5-2025

Institution/Department

Center for Molecular Medicine

Journal Title

Annals of internal medicine

MeSH Headings

Humans, Lyme Disease, Anti-Bacterial Agents, Borrelia burgdorferi, Antibodies, Bacterial, Animals

Abstract

Lyme disease, caused by Borrelia burgdorferi, is the most common vector-borne disease in the United States, and the range of its tick vector continues to expand. Most Lyme disease cases are diagnosed with the onset of the erythema migrans rashes, which can be single or multiple and vary from a homogeneous erythema to bull's-eye patterns. Serologic antibody testing is of low sensitivity at onset but becomes highly sensitive after a few weeks. Early dissemination may lead to neurologic and cardiac complications. Mono- or oligoarticular arthritis may develop in untreated patients. Antibiotic treatment is highly effective, but approximately 10% of treated patients experience persistent symptoms.

ISSN

1539-3704

First Page

65

Last Page

65

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