Fiber: A New Myeloma Prevention Approach with Abundant Positive Effects

Document Type

Article

Publication Date

4-1-2026

Institution/Department

Center for Molecular Medicine

Journal Title

Cancer discovery

MeSH Headings

Humans; Multiple Myeloma (prevention & control, diet therapy); Dietary Fiber (administration & dosage, therapeutic use); Quality of Life; Obesity (diet therapy, complications)

Abstract

In a recent study by Shah, Cogrossi, and colleagues, patients with overweight/obesity and pre-myeloma diseases (monoclonal gammopathy of undetermined significance or smoldering myeloma) were mailed 12 weeks of high-fiber meals, provided with nutritional counseling, and required to track their food intake and weight. The intervention was well tolerated and improved quality of life, metabolic health, gut microbiome composition, and immune system function while supporting stable or improved multiple myeloma disease trajectories. See related article by Shah et al., p. 697.

First Page

623

Last Page

625

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