Document Type

Poster

Publication Date

4-30-2026

Institution/Department

Center for Clinical & Translational Science; Costas T. Lambrew Research Retreat 2026

Abstract

Introduction:

• Long Covid is characterized by persistent symptoms lasting 3+ months after initial SARS-CoV-2 viral infection.

• Over 200 symptoms are associated with Long COVID; the most common complaints include: fatigue, brain fog, shortness of breath, and post-exertional malaise.

• To date, there is no definitive understanding of its pathophysiology, which is needed to guide therapy development.

• The PROMIS (Pathobiology in RECOVER Of Metabolic and Immune Systems) study sought to better understand the role of chronic metabolic inflammation, insulin resistance, and T cell dysfunction in patients with Long COVID when compared to control patients with previous COVID-19 infection but without Long COVID symptoms.

Comments

Presented at the 2026 Costas T. Lambrew Research Retreat

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