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Submissions from 2024

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Effect of Phenobarbital-Based Alcohol Withdrawal Protocol on Provider Practice and Patient Outcomes-A Quality Improvement Study, Nicolette Centanni, Taylor Mezoian, John Gilboy, Jessica Evans, Nicole Hudak, Wendy Craig, and Lesley Gordon

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Antiseizure Drugs and Pharmacogenetics-Is There Signal in the Noise?, David J. Gagnon

Submissions from 2023

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International Analgesia and Sedation Weaning and Withdrawal Practices in Critically Ill Adults: The Adult Iatrogenic Withdrawal Study in the ICU, Scott Bolesta, Lisa Burry, Marc M. Perreault, Céline Gélinas, Kathryn E. Smith, Rebekah Eadie, Federico C. Carini, and Katrianna Saltarelli

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Low-Dose vs Standard Warfarin After Mechanical Mitral Valve Replacement: A Randomized Trial, Michael W. Chu, Marc Ruel, Allen Graeve, Marc W. Gerdisch, Ralph J. Damiano, Robert L. Smith, William Brent Keeling, and Reed D. Quinn

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Outcomes Associated with Empiric Cefepime for Bloodstream Infections Caused by Ceftriaxone-Resistant, Cefepime-Susceptible Escherichia coli and Klebsiella pneumoniae, Brian E. Frescas, Christopher M. McCoy, James Kirby, Robert Bowden, and Nicholas J. Mercuro

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Hospitalists can learn from antimicrobial stewardship programs when it comes to environmentally conscious prescribing., Lesley B. Gordon, Katherine Liu, Minkey Wungwattana, and Dan Meyer

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Beyond antibiotic prescribing rates: first-line antibiotic selection, prescription duration, and associated factors for respiratory encounters in urgent care, Allan M. Seibert, Carly Schenk, Whitney R. Buckel, Payal K. Patel, Nora Fino, Valoree Stanfield, Adam L. Hersh, and Eddie Stenehjem

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Vasopressin-Induced Hyponatremia in Patients With Aneurysmal Subarachnoid Hemorrhage: A Case Series and Literature Review, Hilamber Subba, Richard R. Riker, Susan Dunn, and David J. Gagnon

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Uncomplicated Streptococcal Bacteremia: The Era of Stepdown to Oral Antibiotic Therapy?, Rami Waked, Wendy Craig, Nicholas J. Mercuro, Minkey Wungwattana, Emily Wood MD, and Kristina E. Rokas

Submissions from 2022

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Ceftriaxone to Prevent Pneumonia and Inflammation after Cardiac Arrest (PROTECT): study protocol for a randomized, placebo-controlled trial, David J. Gagnon, Sergey V. Ryzhov, Meghan A. May, Richard R. Riker, Bram Geller, Teresa L. May, Sarah Bockian, Joanne T. deKay, Ashley Eldridge, Thomas Van der Kloot, Patricia Lerwick, Christine Lord, F Lee Lucas, Patrick Mailloux, Barbara McCrum, Meghan Searight, Joel Wirth, Jonathan Zuckerman, Douglas Sawyer, and David B. Seder

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Over-the-counter alkali agents to raise urine pH and citrate excretion: a prospective crossover study in healthy adults, Johann Ingimarsson

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New prescription fills of selective serotonin reuptake inhibitors before and during the COVID-19 pandemic in Los Angeles County, California, Jonathan S. Levin, Joie Acosta, and Laura J. Faherty

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Pharmacist-Driven Transitions of Care Practice Model for Prescribing Oral Antimicrobials at Hospital Discharge, Nicholas J. Mercuro, Corey J. Medler, Rachel M. Kenney, Nancy C. MacDonald, Melinda M. Neuhauser, Lauri A. Hicks, Arjun Srinivasan, George Divine, Amy Beaulac, Erin Eriksson, Ronald Kendall, Marilen Martinez, Allison Weinmann, Marcus Zervos, and Susan L. Davis

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Predictors of discordant MRSA nares and respiratory cultures in patients with pneumonia, Nicholas P. Palisano, Christina F. Yen, and Nicholas J. Mercuro

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Letermovir for Cytomegalovirus Prevention in Adolescent Patients Following Hematopoietic Cell Transplantation, Nicole P Daukshus, Anthony Cirincione, Molly Siver, Sherry Mathew, Binni Kunvarjee, Amelia Chan, Jaap Jan Boelens, Susan K. Seo, Genovefa A. Papanicolaou, and Nancy A. Kernan

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A prospective, randomized trial of the effect of buprenorphine continuation versus dose reduction on pain control and post-operative opioid use, Aurora Quaye, Kristen Silvia, Janelle Richard, Yussr Ibrahim, Wendy Craig, and Clifford J. Rosen

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Comment: A Review of Pharmacologic Neurostimulant Use During Rehabilitation and Recovery After Brain Injury, Richard R. Riker, Paige Weaver, and David J. Gagnon

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The practice and embodiment of "goofballs": A qualitative study exploring the co-injection of methamphetamines and opioids, Kinna Thakarar

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Opioid Prescribing Patterns Before, During, and After Critical Illness: An Observational Study, Chelsea Wampole, Ariel McKenna, Richard R. Riker, Teresa L. May, David B. Seder, Dawn Abram, Gilles L. Fraser, and David J. Gagnon

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Management of Venous Thromboembolism in Morbid Obesity With Rivaroxaban or Warfarin, Paige Weaver, Tsz Hin Ng, Thomas Breeden, Stephanie B. Edwin, and Bradley Haan

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The Role of Pharmacotherapeutic Agents in Children with Desmoid Tumors, Aaron R. Weiss

Submissions from 2020

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Evaluation of a Burn Pain and Sedation Clinical Practice Guideline: A Before and After Study The Before Cohort, Bethany W. Carrington, Kathryn E. Smith, and Rosemary E. Paine

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A Retrospective Review of the Safety and Efficacy of Direct Oral Anticoagulants (DOACs) in Obese Patients who Underwent Electrical Cardioversion, Matt Cox, Brian Carlone, Jaclynne Gowen, Amber Rollins, and Wes Zemrak

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Integrating Interprofessional Case Scenarios, Allied Embedded Actors, and Teaching Into Formative Observed Structured Clinical Exams., Peggy R Cyr, Julie M Schirmer, Victoria Hayes, Corinn Martineau, and Meghan Keane

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Evaluation of a perioperative anticoagulation protocol in renal transplantation: a retrospective analysis., Sierra Ferreira, Brian Carlone, and Marizela Savic

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Impact of pharmacist-led medication reconciliation and education at an outpatient dialysis center, Kayla Harris, Marizela Savi, and Corinn Martineau

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Clinical Performance Measures for Neurocritical Care: A Statement for Healthcare Professionals from the Neurocritical Care Society., Sarah Livesay, Herbert Fried, David Gagnon, Navaz Karanja, Abhijit Lele, Asma Moheet, Casey Olm-Shipman, Fabio Taccone, David Tirschwell, Wendy Wright, J Claude Hemphill Iii, and Neurocritical Care Society

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Improving HPV Vaccination Rates: A Stepped-Wedge Randomized Trial, Rebecca B. Perkins, Aaron Legler, Emily Jansen, Judith Bernstein, Natalie Pierre-Joseph, Terresa J. Eun, Dea L. Biancarelli, Thomas J. Schuch, Karin Leschly, Anny T. Fenton, William G. Adams, Jack A. Clark, Mari-Lynn Drainoni, and Amresh Hanchate

Submissions from 2019

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Low-Dose Prothrombin Complex Concentrate in Patients with Left Ventricular Assist Devices., Caitlin S Brown, Wesley R Zemrak, Kaitlin J Dyer, and Stephen Rolfe

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Joint Annual Wellness Visit Scheduling, Rob Chamberlin, Jennifer Bliss, Andrea Lai, Paula Dougherty, Deb Swett, Logan Merrithew, Pam Stevens, and Scott Williams

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Multicenter study to evaluate the benefits of technology-assisted workflow on i.v. room efficiency, costs, and safety., Stephen F Eckel, Jordyn P Higgins, Elizabeth Hess, Thomas Cerbone, Jennifer B Civiello, Christian Conley, Nilofar Jafari, Shailly Shah, Stephen L Speth, and Lynn Thornton

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Innovative Interprofessional Improvement Project Increases Adherence to Vitamin D Supplementation After Newborn Discharge...2019 AWHONN Convention, June 8-12, 2019, Atlanta, Georgia, Jamie Fey, Noah Diminick, Heidi E. Morin, Kathleen Cyr, Jonathan Bourque, and Patricia J. Crosby

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Pharmacist-Managed Inpatient Dofetilide Initiation Program: Description and Adherence Rate Post-Root Cause Analysis., Elena You Jung Ko, Charles M Carpenter, David J Gagnon, and Anne M Andrle

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Prospective assessment of sedation scales and wakefulness in medical and neurological ICU patients., Pasquale Marotte, Caitlin Brown, Teresa May, Richard Riker, and Gilles Fraser

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Major publications in critical care pharmacotherapy literature in 2018., Andrea Sikora Newsome, Brittany D Bissell, Lisa D Burry, Aubrey A Defayette, David J Gagnon, Brian W Gilbert, C Joseph Kramer, Christopher J Miller, Michael Semanco, Melanie N Smith, and Drayton A Hammond

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Evaluation the transition from dexmedetomidine to enteral clonidine in adult ICU patients., Nicholas Pozzessere, Richard Riker, Gilles Fraser, David Gagnon, Jonathan Rud, Allison Fluke, and Elizabeth Glisic

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Evaluations of serum potassium during pentobarbital administration in critically ill patients., Kathryn Smith, William Crall, David Gagnon, Elizabeth Glisic, David Seder, and Richard Riker

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Beyond Opioids for Pain Management in Adult Critically Ill Patients., Chelsea R. Wampole and Katheryn E. Smith

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Beyond Opioids for Pain Management in Adult Critically Ill Patients., Chelsea R Wampole and Kathryn E Smith

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Loperamide-Associated Opioid Use Disorder and Proposal of an Alternative Treatment with Buprenorphine., Lee A Wolfrum, Aimee S Nordmeyer, Christopher W Racine, and Stephanie D Nichols

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Low-dose compared to manufacturer-recommended dose four-factor prothrombin complex concentrate for acute warfarin reversal., Wesley Zemrak, Francis Manuel, Kathryn E Smith, Stephen Rolfe, Timothy Hayes, Robert L Trowbridge, Brian Carlone, and David Seder

Submissions from 2018

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In the Middle of Difficulty Lies Opportunity.-Albert Einstein., Richard R Riker and Gilles L Fraser

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Valproate free serum concentrations: More complex than simple formulas., Richard R Riker, David Gagnon, Teresa May, Gilles Fraser, and David Seder

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Tailored Rabbit Antithymocyte Globulin Induction Dosing for Kidney Transplantation., Namita Singh, Ana P Rossi, Marizela Savic, Ronald J Rubocki, Mark G Parker, and John P Vella

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Accuracy of Point-of-Care Blood Glucose Level Measurements in Critically Ill Patients with Sepsis Receiving High-Dose Intravenous Vitamin C., Kathryn E Smith, Caitlin S Brown, Bridget M Manning, Teresa May, Richard R Riker, Patricia A Lerwick, Timothy L Hayes, and Gilles L Fraser

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Use of ceftolozane-tazobactam in a cystic fibrosis patient with multidrug-resistant pseudomonas infection and renal insufficiency., Katie Stokem, Jonathan B Zuckerman, David P Nicolau, Minkey Wungwattana, and Edmund H Sears

Submissions from 2017

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Repurposing valproate, enteral clonidine, and phenobarbital for comfort in adult ICU patients: a literature review with practical considerations., David J Gagnon, Gabriel V Fontaine, Richard R Riker, and Gilles L Fraser

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Valproate for agitation in critically ill patients: a retrospective study., David J. Gagnon, Gabriel V Fontaine, Kathryn E. Smith, Richard R. Riker, Russell R Miller, Patricia A. Lerwick, F L. Lucas, John T. Dziodzio, Kristen C. Sihler, and Gilles L. Fraser

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Pediatric patient-centered transitions from hospital to home: improving the discharge medication process., Leah A Mallory, Noah P Diminick, Jonathan P Bourque, Meredith R Bryden, Jessica L Miller, Nancy M Nystrom, Melanie R Lord, and Lorraine L McElwain

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Outcomes in Cardiac Arrest Vary by Center After Correction for Case Mix and Severity of Illness., Teresa May, Philip Stone, Gill Fraser, Richard Riker, and David Seder

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A retrospective analysis comparing oral stepdown therapy for enterobacteriaceae bloodstream infections: fluoroquinolones versus beta-lactams., Nicholas J. Mercuro, Patricia Stogsdill, and Minkey Wungwattana

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Cefepime-induced neurotoxicity: a systematic review., Lauren E Payne, David J Gagnon, Richard R Riker, David B Seder, Elizabeth K Glisic, Jane G Morris, and Gilles L Fraser

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Chronic pain patients' perspectives of medical cannabis., Brian J Piper, Monica L Beals, Alexander T Abess, Stephanie D Nichols, Maurice W Martin, Catherine M Cobb, and Rebecca M DeKeuster

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A new tool to tackle the opioid epidemic: description, utility, and results from the Maine Diversion Alert Program., Brian J Piper, Clare E Desrosiers, Harriet C Fisher, Kenneth L McCall, and Stephanie D Nichols

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Valproate protein binding is highly variable in ICU patients and not predicted by total serum concentrations: a case series and literature review., Richard R Riker, David J Gagnon, Colman Hatton, Teresa May, David B Seder, Katie Stokem, and Gilles L Fraser

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An evaluation of the opportunities for collaborative practice occurring in and the impact of interprofessional education on advanced pharmacy practice experiences., Elena M Umland, Jonathan Valenzano, Caitlin Brown, and Carolyn Giordano

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Tacrolimus interaction with nafcillin resulting in significant decreases in tacrolimus concentrations: a case report., Minkey Wungwattana and Marizela Savic

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Low-dose prothrombin complex concentrate for warfarin-associated intracranial hemorrhage with INR less than 2.0., Wesley R Zemrak, Kathryn E Smith, Stephen S Rolfe, Teresa May, Robert L Trowbridge, Timothy L Hayes, Gene A Grindlinger, and David B Seder

Submissions from 2016

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Clinafloxacin for treatment of Burkholderia cenocepacia infection in a cystic fibrosis patient, Akshu Balwan, David P Nicolau, Minkey Wungwattana, Jonathan B Zuckerman, and Valerie Waters

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Intended and unintended consequences of constraining clinician prescribing: the case of antipsychotics., John W Devlin, Pamela Smithburger, Jason M Kane, Gilles L. Fraser, and Yoanna Skrobik

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Inadequacy of Headache Management After Subarachnoid Hemorrhage., Elizabeth K Glisic, Linda Gardiner, Linda Josti, Elizabeth Dermanelian, Sandra Ridel, John Dziodzio, Barbara McCrum, Ben Enos, Patricia Lerwick, Gilles L Fraser, Paul Muscat, Richard R Riker, Robert Ecker, Jeffrey Florman, and David B Seder

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Free serum valproate concentration more reliable than total concentration in critically ill patients., Colman Hatton, Richard R. Riker, David J. Gagnon, Teresa May, David B. Seder, and Gilles L. Fraser

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A case of possible iatrogenic ketamine-Induced mania in a patient being treated for postoperative pain., Stephanie D. Nichols, Maya Bulman, Annya Tisher, and John J. Campbell

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Use and misuse of opioids in Maine: results from pharmacists, the prescription monitoring, and the diversion alert programs., Brian J Piper, Clare E Desrosiers, John W Lipovsky, Matthew A Rodney, Robert P Baker, Kenneth L McCall, Stephanie D. Nichols, and Sarah L Martin

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Sedation quality in intensive care: which interventions work?, Richard R. Riker and Gilles L. Fraser

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Implementation of a simplistic bivalirudin-warfarin transition protocol Is associated with improved achievement of INR values within the therapeutic range., Amber R Rollins, Kathryn E Smith, and Wesley R Zemrak

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The evolving paradigm of individualized postresuscitation care after cardiac arrest., David B Seder, Christine Lord, and David J Gagnon

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Reply to Young, Ochi, and Marimuthu., John C Williamson, Haley G Gibbs, Christopher A Ohl, James W Johnson, James R Beardsley, Vera P Luther, and Kristina E E Rokas

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Thrombotic complications following the administration of high-dose prothrombin complex concentrate for acute warfarin reversal., Wesley R Zemrak, Erin Kelley, Nicole L Kovacic, Deirdre M Mooney, Jane G Morris, Casey Z MacVane, and Jeffrey A Rosenblatt

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Haematoma expansion and vitamin K antagonist reversal., Wesley R. Zemrak, Kathryn E. Smith, David J. Gagnon, Stephen S. Rolfe, and David B. Seder

Submissions from 2015

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Methadone versus morphine for treatment of neonatal abstinence syndrome: a prospective randomized clinical trial., M S Brown, M J Hayes, and L M Thornton

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SLEAP: a wake-up call to question the oversimplification of ICU delirium., Gilles L Fraser, David J Gagnon, and Richard R Riker

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Prophylactic antibiotics are associated with a lower incidence of pneumonia in cardiac arrest survivors treated with targeted temperature management., David J Gagnon, Niklas Nielsen, Gilles L Fraser, Richard R Riker, John Dziodzio, Kjetil Sunde, Jan Hovdenes, Pascal Stammet, Hans Friberg, Sten Rubertsson, Michael Wanscher, and David B Seder

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Transition from dexmedetomidine to enteral clonidine for ICU sedation: an observational pilot study., David J Gagnon, Richard R Riker, Elizabeth K Glisic, Andrew Kelner, Hilary M Perrey, and Gilles L Fraser

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Etomidate in sepsis: understanding the dilemma., David J Gagnon and David B Seder

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Development and evaluation of a multidisciplinary controlled substances committee within a patient-centered medical home., Stephanie A Gernant, Rachel Bastien, and Andrea Lai

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Key articles and guidelines in the management of patients undergoing cardiac surgery., Ian B Hollis, Douglas L Jennings, Carrie S Oliphant, William L Baker, Estella M Davis, J Erin Allender, Wesley R Zemrak, and Christopher Ensor

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Assessment of food intake, obesity, and health risk among the homeless in Rhode Island., Diane C Martins, Kathleen S Gorman, Robin J Miller, Leah Murphy, Sekboppa Sor, Jonah C Martins, and Maria L Vecchiarelli

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Analgesia, sedation, and neuromuscular blockade during targeted temperature management after cardiac arrest., Richard R Riker, David J Gagnon, Teresa May, David B Seder, and Gilles L Fraser

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Serotonin syndrome following methylene blue administration during cardiothoracic surgery., Christina J Smith, Dorothy Wang, Anna Sgambelluri, Robert S Kramer, and David J Gagnon

Submissions from 2014

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Randomized ICU trials do not demonstrate an association between interventions that reduce delirium duration and short-term mortality: a systematic review and meta-analysis., Nada S Al-Qadheeb, Ethan M Balk, Gilles L Fraser, Yoanna Skrobik, Richard R Riker, John P Kress, Shawn Whitehead, and John W Devlin

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Cost effectiveness of a benzodiazepine vs a nonbenzodiazepine-based sedation regimen for mechanically ventilated, critically ill adults., Justin J Bioc, Chelsea Magee, James Cucchi, Gilles L Fraser, Joseph F Dasta, Roger A Edwards, and John W Devlin

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Implementation of the systems approach to improve a pharmacist-managed vancomycin dosing service., David J Gagnon, Russel Roberts, and Lynne Sylvia

Comparison of a pediatric-specific and an institution-wide antibiogram, istina Smith, Jonathan Bourque, and Renee Fallon

Submissions from 2011

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Future directions of stroke prevention in atrial fibrillation: the potential impact of novel anticoagulants and stroke risk stratification., K P Cabral, J Ansell, and E M Hylek

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Correlation of bivalirudin dose with creatinine clearance during treatment of heparin-induced thrombocytopenia., Courtney L Runyan, Katherine P Cabral, Richard R Riker, David Redding, Teresa May, David B Seder, Marizela Savic, Jacqueline Hedlund, Stuart Abramson, and Gilles L Fraser

Submissions from 1951

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Fatal pancytopenia following anti-histamine administration, C R. GLASSMIRE