Submissions from 2015
Parent stem cells can serve as niches for their daughter cells., Ana Pardo-Saganta, Purushothama Rao Tata, Brandon M Law, Borja Saez, Ryan Dz-Wei Chow, Mythili Prabhu, Thomas Gridley, and Jayaraj Rajagopal
DLL4/Notch1 and BMP9 interdependent signaling induces human endothelial cell quiescence via P27KIP1 and thrombospondin-1., Bahman Rostama, Jacqueline E Turner, Guy T Seavey, Christine R Norton, Thomas Gridley, Calvin P H Vary, and Lucy Liaw
Cthrc1 controls adipose tissue formation, body composition, and physical activity., J Patrizia Stohn, Qiaozeng Wang, Matthew E Siviski, Kevin Kennedy, Yong-Ri Jin, Doreen Kacer, Victoria DeMambro, Lucy Liaw, Calvin P Vary, Clifford J Rosen, Igor Prudovsky, and Volkhard Lindner
SLUG is a direct transcriptional repressor of PTEN tumor suppressor., Berna Uygur, Katrina Abramo, Evgenia Leikina, Calvin Vary, Lucy Liaw, and Wen-Shu Wu
Loss of Snail2 favors skin tumor progression by promoting the recruitment of myeloid progenitors., Ana Villarejo, Patricia Molina-Ortiz, Yenny Montenegro, Gema Moreno-Bueno, Saleta Morales, Vanesa Santos, Tom Gridley, Mirna A Pérez-Moreno, Héctor Peinado, Francisco Portillo, Carmela Calés, and Amparo Cano
Fibroblast growth factor signaling in the vasculature., Xuehui Yang, Lucy Liaw, Igor Prudovsky, Peter C Brooks, Calvin Vary, Leif Oxburgh, and Robert Friesel
BMP9 crosstalk with the hippo pathway regulates endothelial cell matricellular and chemokine responses., Kira Young, Eric Tweedie, Barbara Conley, Jacquelyn Ames, MaryLynn FitzSimons, Peter Brooks, Lucy Liaw, and Calvin P H Vary
Expression of adenosine receptors in monocytes from patients with bronchial asthma., Ksenia Yuryeva, Irina Saltykova, Ludmila Ogorodova, Natalya Kirillova, Evgeny Kulikov, Elena Korotkaya, Yulia Iakovleva, Igor Feoktistov, Alexey Sazonov, and Sergey Ryzhov
Submissions from 2014
Improved survival outcomes in cancer patients with hereditary hemorrhagic telangiectasia., Christine W Duarte, Kimberly Murray, F Lee Lucas, Kathleen Fairfield, Heather Miller, Peter Brooks, and Calvin P H Vary
Elevated plasma levels of the pituitary hormone Cthrc1 in individuals with red hair but not in patients with solid tumors., Christine W Duarte, J Patrizia Stohn, Qiaozeng Wang, Ivette F Emery, Andrew Prueser, and Volkhard Lindner
Cryptic collagen IV promotes cell migration and adhesion in myeloid leukemia., Amanda J Favreau, Calvin P H Vary, Peter C Brooks, and Pradeep Sathyanarayana
FOXD1 promotes nephron progenitor differentiation by repressing decorin in the embryonic kidney., Jennifer L Fetting, Justin A Guay, Michele J Karolak, Renato V Iozzo, Derek C Adams, David E Maridas, Aaron C Brown, and Leif Oxburgh
Overview of genetic tools and techniques to study Notch signaling in mice., Thomas Gridley and Andrew K Groves
Lightening up a notch: notch regulation of energy metabolism., Thomas Gridley and Shingo Kajimura
Regulation of the follistatin gene by RSPO-LGR4 signaling via activation of the WNT/β-catenin pathway in skeletal myogenesis., Xiang Hua Han, Yong-Ri Jin, Leonard Tan, Tatiana Kosciuk, Jin-Seon Lee, and Jeong Kyo Yoon
Deficiency of Sef is associated with increased postnatal cortical bone mass by regulating Runx2 activity., Qing He, Xuehui Yang, Yan Gong, Dmitry Kovalenko, Ernesto Canalis, Clifford J Rosen, and Robert E Friesel
Effect of sustained postnatal systemic inflammation on hippocampal volume and function in mice., Shadi N Malaeb, Jonathan M Davis, Ilka M Pinz, Jennifer L Newman, Olaf Dammann, and Maribel Rios
Genomic imprinting variations in the mouse type 3 deiodinase gene between tissues and brain regions., M Elena Martinez, Marika Charalambous, Aabida Saferali, Steven Fiering, Anna K Naumova, Donald St Germain, Anne C Ferguson-Smith, and Arturo Hernandez
Bone morphogenetic protein signaling in nephron progenitor cells., Leif Oxburgh, Aaron C. Brown, Sree Deepthi Muthukrishnan, and Jennifer L. Fetting
Common features of microRNA target prediction tools., Sarah M Peterson, Jeffrey A Thompson, Melanie L Ufkin, Pradeep Sathyanarayana, Lucy Liaw, and Clare Bates Congdon
Transitory FGF treatment results in the long-lasting suppression of the proliferative response to repeated FGF stimulation., Ashleigh Poole, Nicholas Knowland, Emily Cooper, Rebecca Cole, Hongchuan Wang, Lucas Booth, Doreen Kacer, Francesca Tarantini, Robert Friesel, and Igor Prudovsky
Notch signal integration in the vasculature during remodeling., Bahman Rostama, Sarah M Peterson, Calvin P H Vary, and Lucy Liaw
miR-125a regulates cell cycle, proliferation, and apoptosis by targeting the ErbB pathway in acute myeloid leukemia., Melanie L Ufkin, Sarah Peterson, Xuehui Yang, Heather Driscoll, Christine Duarte, and Pradeep Sathyanarayana
Transfer of intracellular HIV Nef to endothelium causes endothelial dysfunction., Ting Wang, Linden A Green, Samir K Gupta, Chul Kim, Liang Wang, Sharilyn Almodovar, Sonia C Flores, Igor A Prudovsky, Paul Jolicoeur, Ziyue Liu, and Matthias Clauss
Submissions from 2013
The snail family gene snai3 is not essential for embryogenesis in mice., Cara K Bradley, Christine R Norton, Ying Chen, Xianghua Han, Carmen J Booth, Jeong Kyo Yoon, Luke T Krebs, and Thomas Gridley
Role for compartmentalization in nephron progenitor differentiation., Aaron C Brown, Sree Deepthi Muthukrishnan, Justin A Guay, Derek C Adams, Dillon A Schafer, Jennifer L Fetting, and Leif Oxburgh
Compensatory regulation of the Snai1 and Snai2 genes during chondrogenesis., Ying Chen and Thomas Gridley
The SNAI1 and SNAI2 proteins occupy their own and each other's promoter during chondrogenesis., Ying Chen and Thomas Gridley
Sprouty4 regulates endothelial cell migration via modulating integrin β3 stability through c-Src., Yan Gong, Xuehui Yang, Qing He, Lindsey Gower, Igor Prudovsky, Calvin P H Vary, Peter C Brooks, and Robert E Friesel
Notch1 activation in embryonic VE-cadherin populations selectively blocks hematopoietic stem cell generation and fetal liver hematopoiesis., Yuefeng Tang, Hao Bai, Sumithra Urs, Zack Wang, and Lucy Liaw
Spry1 and Spry4 differentially regulate human aortic smooth muscle cell phenotype via Akt/FoxO/myocardin signaling., Xuehui Yang, Yan Gong, Yuefeng Tang, Hongfang Li, Qing He, Lindsey Gower, Lucy Liaw, and Robert E Friesel
Submissions from 2012
Insulin-like growth factor binding protein-4 differentially inhibits growth factor-induced angiogenesis., Liangru W Contois, Desiree P Nugent, Jennifer M Caron, Alexandra Cretu, Eric Tweedie, Abebe Akalu, Leonard Liebes, Robert Friesel, Clifford Rosen, Calvin Vary, and Peter C Brooks
The Notch-regulated ankyrin repeat protein is required for proper anterior-posterior somite patterning in mice., Luke T Krebs, Cara K Bradley, Christine R Norton, Jingxia Xu, Kathleen F Oram, Christa Starling, Michael L Deftos, Michael J Bevan, and Thomas Gridley
Cthrc1, a novel circulating hormone regulating metabolism., J Patrizia Stohn, Nicole G Perreault, Qiaozeng Wang, Lucy Liaw, and Volkhard Lindner
Histone deacetylase activity selectively regulates notch-mediated smooth muscle differentiation in human vascular cells., Yuefeng Tang, Joshua M Boucher, and Lucy Liaw
Mortality in rural locations after severe injuries from motor vehicle crashes., Lori L Travis, David E Clark, Amy E Haskins, and Joseph A Kilch
Cellular signaling and biological functions of R-spondins., Jeong Kyo Yoon and Jin-Seon Lee
Submissions from 2011
Isolation and culture of cells from the nephrogenic zone of the embryonic mouse kidney., Aaron C Brown, Ulrika Blank, Derek C Adams, Michele J Karolak, Jennifer L Fetting, Beth L Hill, and Leif Oxburgh
BMP signaling in the nephron progenitor niche., Leif Oxburgh, Aaron C Brown, Jennifer Fetting, and Beth Hill
Endoglin regulates cancer-stromal cell interactions in prostate tumors., Diana Romero, Christine O'Neill, Aleksandra Terzic, Liangru Contois, Kira Young, Barbara A Conley, Raymond C Bergan, Peter C Brooks, and Calvin P H Vary
Mechanisms of TGF-β-induced differentiation in human vascular smooth muscle cells., Yuefeng Tang, Xuehui Yang, Robert E Friesel, Calvin P H Vary, and Lucy Liaw
SLUG promotes prostate cancer cell migration and invasion via CXCR4/CXCL12 axis., Berna Uygur and Wen-Shu Wu
RhoA-mediated signaling in Notch-induced senescence-like growth arrest and endothelial barrier dysfunction., Deepak Venkatesh, Natalie Fredette, Bahman Rostama, Yuefeng Tang, Calvin P H Vary, Lucy Liaw, and Sumithra Urs
Submissions from 2010
Follistatin-like 1 regulates renal IL-1β expression in cisplatin nephrotoxicity., Derek C Adams, Michele J Karolak, Barry W Larman, Lucy Liaw, James D Nolin, and Leif Oxburgh
Two novel human NUMB isoforms provide a potential link between development and cancer., Aldona Karaczyn, Mahmud Bani-Yaghoub, Roger Tremblay, Chris Kubu, Rebecca Cowling, Tamara L Adams, Igor Prudovsky, Douglas Spicer, Robert Friesel, Calvin Vary, and Joseph M Verdi
A role for NRAGE in NF-kappaB activation through the non-canonical BMP pathway., Nicholas Matluk, Jennifer A Rochira, Aldona Karaczyn, Tamara Adams, and Joseph M Verdi
Endoglin phosphorylation by ALK2 contributes to the regulation of prostate cancer cell migration., Diana Romero, Aleksandra Terzic, Barbara A Conley, Clarissa S Craft, Borko Jovanovic, Raymond C Bergan, and Calvin P H Vary
The contribution of the Tie2+ lineage to primitive and definitive hematopoietic cells., Yuefeng Tang, Anne Harrington, Xuehui Yang, Robert E Friesel, and Lucy Liaw
Notch and transforming growth factor-beta (TGFbeta) signaling pathways cooperatively regulate vascular smooth muscle cell differentiation., Yuefeng Tang, Sumithra Urs, Joshua Boucher, Tyler Bernaiche, Deepak Venkatesh, Douglas B Spicer, Calvin P H Vary, and Lucy Liaw