The Center for Molecular Medicine (CMM) was established in 1997 as a Center within Maine Medical Center Research Institute with the vision of performing cutting edge biomedical research to discover the molecular mechanisms of human disease, and to harness new knowledge in developmental biology and stem cells for regenerative medicine approaches. The investigators at CMM are committed to translating basic science discoveries to innovative approaches to diagnose and treat human disease.

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Submissions from 2026

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Enhanced metabolic benefits of dietary methionine restriction in cold resistant hybrid UCP1-deficient mice, Rea Victoria Anunciado-Koza, Crystal Bilodeau, Diana Cooke, Gene P. Ables, and Robert A. Koza

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Timeliness of Antiresorptive Consolidation After Anabolic Therapy for Primary Fracture Prevention: A U.S. Cohort Study, Sanaa Badour, Rozalina G. McCoy, Mark Takagi, Alexander O. Everhart, Joseph Parimi, Jeph Herrin, Pinar Karaca-Mandic, and Clifford J. Rosen

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Gut-Derived FGF15 Modulates Lean Mass, Bone, and Bile Acid Responses to Weight Loss, Nadejda Bozadjieva-Kramer, Garrett McMahon, Ziru Li, Jordan Wean, Jae Hoon Shin, Andriy Myronovych, Robert W. O'Rourke, Ormond A. MacDougald, and Randy J. Seeley

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Thermogenesis is limited by cellular competence, Aaron C. Brown

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In C57BL/6J mice, weight loss in previously obese mice reduced bone mass and shifted the cortical bone metabolome., Carolyn Chlebek, Casey McAndrews, Benjamin Aaronson, Hope D Welhaven, Kanglun Yu, Samantha N Costa, Joseph Shaver, Sophia Silvia, Victoria E DeMambro, Ronald K June, Meghan E McGee-Lawrence, and Clifford J. Rosen

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Expansion of bone marrow adipocytes in obese mice leads to PD-L1-driven bone marrow immunosuppression and osteoclastogenesis, Samantha N. Costa, Carolyn Chlebek, Lindsey Gray, Peter Caradonna, Sergey Ryzhov, and Clifford J. Rosen

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Fiber: A New Myeloma Prevention Approach with Abundant Positive Effects, Heather Fairfield and Michaela R. Reagan

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Candidate Interaction Partners of Calpain-5 Suggest Clues to Its Involvement in Neovascular Inflammatory Vitreoretinopathy, Jozsef Gal, Vimala Bondada, Rachel Crasta, Dorothy E. Croall, Calvin Vary, and James W. Geddes

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Exercise training decreases Neuregulin-1 concentrations in HER2-positive breast cancer patients undergoing adjuvant trastuzumab: the CARDAPAC study, Quentin Jacquinot, Gaël Ennequin, Antoine Falcoz, Douglas Sawyer, Nathalie Meneveau, and Fabienne Mougin

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Cardiovascular signaling proteins as predictors of the cardiac effects of doxorubicin treatment in children with acute lymphoblastic leukemia, Steven E. Lipshultz, Holly M. Smith, Stephen E. Sallan, and Douglas B. Sawyer

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GLP-1 Receptor Agonists, Clifford J. Rosen and Julie R. Ingelfinger

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Beyond mecA: a two-tiered mechanism and regulatory rewiring drive high-level ceftaroline resistance in clinical MRSA, Melissa Sassman, Michele Karolak, Margeurite Dallaire, Claire E. Schaffer, Carlos Gartner, Calvin Vary, Roberto R. Rosato, and Adriana E. Rosato

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Fostering the next generation of bone marrow adiposity researchers: the 3rd International Bone Marrow Adiposity Society Summer School 2025 report, Drenka Trivanović, Tânia Amorim, Adriana Roque, Souad Daamouch, Young-Eun Park, Tiange Feng, and Maxime Bedez

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Measuring deiodinase activity - a need for standardization?, Joëlle Wiersema, Petra Mohácsik, Balázs Gereben, Arturo Hernandez, Selmar Leeuwenburgh, Marcel Meima, and W Edward Visser

Submissions from 2025

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Is Pathogen Molecular Testing Reshaping Outpatient Antibiotic Prescribing?, Barbara D. Alexander, William D. Irish, Adriana E. Rosato, Barry I. Eisenstein, Maren S. Fragala, and Steven E. Goldberg

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Increased spontaneous physical activity in female MEST-deficient mice protects against diet-induced obesity., Rea Victoria P Anunciado-Koza, M Elena Martinez, Victoria DeMambro, Arturo Hernandez, and Robert A Koza

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Building a collaborative ecosystem across the IDeA-CTR networks in response to a public health emergency., A Jerrod Anzalone, Sharon Patrick, Amber Abel, Brad Price, Elizabeth Reisher, Kent Ripplinger, Mary Emmett, Ronald Horswell, San Chu, William B Hillegass, Francisco S Sy, Brian Melancon, H Timothy Bunnell, Susan L. Santangelo, and Clifford J. Rosen

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Prolactin: A Key Immunoregulator in Viral Infections and Autoimmune Diseases, Mina Asadikaram, Saeed Bahrampour, Mahdis Rahimi Naiini, Abdollah Jafarzadeh, Clifford Rosen, and Gholamreza Asadikaram

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Activity of Cardiomyocyte Type 3 Deiodinase After Myocardial Infarction Influences Cardiac Recovery in Females, Maigen Bethea, Tyler Cook, Preston Stafford, Leslie Knaub, Maria Elena Martinez, Bjoern Schniedewind, Uwe Christians, Jasmine Jay Hendrix, and Arturo Hernandez

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Guidance on the management of asymptomatic blood donors who test positive for Babesia, Evan M. Bloch, Jeremy W. Jacobs, Edouard Vannier, Gary P. Wormser, Jeffrey A. Gelfand, Vijay K. Sikand, Howard M. Heller, and robert p. smith md

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Long COVID treatment trials: still more questions than answers?, Carolyn T Bramante and Clifford J. Rosen

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Dietary effects on cardiac lipid composition, mitochondrial respiration, stress proteins and thermal tolerance in the American lobster (Homarus americanus), Melissa C. Butler, Yulica Santos-Ortega, Calvin P. Vary, Anyonya R. Guntur, and Ilka M. Pinz

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Fshr gene depletion prevents recognition memory loss, fat accrual and bone loss in Alzheimer's mice, Uliana Cheliadinova, Steven Sims, Funda Korkmaz, Darya Vasilyeva, Victoria Laurencin, Judit Gimenez-Roig, Georgii Pevnev, Guzel Burganova, and Clifford J. Rosen

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Atlas of Fshr expression from novel reporter mice., Hongqian Chen, Hui-Qing Fang, Jin-Tao Liu, Shi-Yu Chang, Li-Ben Cheng, Ming-Xin Sun, Jian-Rui Feng, Ze-Min Liu, Yong-Hong Zhang, Clifford J. Rosen, and Peng Liu

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Isolation and Characterization of Primary Bone Marrow Adipocytes in Rodent Models, Samantha N. Costa, Carolyn Chlebek, and Clifford J. Rosen

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Altered metabolomics and inflammatory transcriptomics in human bone marrow adipocytes after acute high calorie diet and acute fasting, Samantha N. Costa, Gisela Pachón-Peña, Julie Dragon, Scott Tighe, and Calvin Vary

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Adult Long Coronavirus Disease 2019: Definition, Prevalence Pathophysiology, and Clinical Manifestations., Ivette Emery and Clifford J. Rosen

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Age-Related Changes in the Clinical Picture of Long COVID., Mindy J Fain, Benjamin D Horne, Leora I Horwitz, Tanayott Thaweethai, Meredith Greene, Mady Hornig, Ariela R Orkaby, Clifford J. Rosen, and Christine S Ritchie

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Omics characteristics and epigenetic modifications of adipose-derived stem cells., Tiange Feng, Clifford J. Rosen, and Ziru Li

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Atenolol, alone or in combination with PTH, has a modest effect on bone in female C57BL/6J mice., Rebecca L Fontaine, Daniel J Brooks, Deborah Barlow, Ryan J Neilson, Christine W Lary, Karen L Houseknecht, and Katherine J Motyl

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Ceftriaxone to prevent early-onset pneumonia in comatose patients after out-of-hospital cardiac arrest: a pilot randomized controlled trial and resistome assessment (PROTECT)., David J Gagnon, Kristin M Burkholder, Alexandra J Weissman, Richard R. Riker, Sergey Ryzhov, Teresa May, John DiPalazzo, Joanne dekay, Laccey Knudsen, Meagan W Moore, Mary Weatherbee, Muriel Kelly, Adane S Nigatu, Joseph L Sevigny, Stephen Simpson, W Kelley Thomas, Clifton W Callaway, Bram J. Geller, Douglas Sawyer, and David Seder

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Vitamin A deficiency and male-specific effects on heart function in mice, Ian M. Gans, Elena Chepurko, Vadim Chepurko, Grazina A. Mangoba, Mary Ann Asson-Batres, and Calvin P. Vary

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Retinoic acid promotes expression of inflammatory factors in proliferative adult human heart cells, Ian M. Gans, Amanda J. Lessard, Sergey Ryzhov, Calvin P. Vary, and Douglas B. Sawyer

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Reduction of neuronal activity mediated by blood-vessel regression in the adult brain., Xiaofei Gao, Xing-Jun Chen, Meng Ye, Jun-Liszt Li, Nannan Lu, Di Yao, Bo Ci, Fei Chen, Lijun Zheng, Yuanlei Yue, Tingbo Li, Jiafu Lin, Volkhard Lindner, Robert M Bachoo, and Woo-Ping Ge

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Time Course of Biochemical and Metabolic Parameters During and After COVID-19., Zohreh-Al-Sadat Ghoreshi, Mojtaba Abbasi-Jorjandi, Gholamreza Asadikaram, Mohsen Sharif-Zak, Mohammad Khaksari Haddad, Ali Afgar, Nasir Arefinia, Shahriar Dabiri, and Clifford J. Rosen

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FGF21 promotes longevity in diet-induced obesity through metabolic benefits independent of growth suppression, Christy M. Gliniak, Ruth Gordillo, Yun-Hee Youm, Qian Lin, Clair Crewe, and Clifford J. Rosen

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A synbiotic medical food improves gut barrier function, reduces immune responses, and inhibits osteoclast activity in models of postmenopausal bone loss aligned with clinical outcomes, Ryan S. Green, Tyler Roy, Daniela Diaz-Infante Morales, Claire Morrow, Ryan Neilson, Eric M. Schott, Mark R. Charbonneau, Alicia E. Ballok, and Katherine J. Motyl

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Modified Versions of Natural Frozen Embryo Transfers Do Not Impact Live Births, Courtney Hargreaves, Wendy Craig, Denny Sakkas, Thomas L. Toth, and Denis Vaughan

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Weekly Insulins and Therapeutic Burden in Type 2 Diabetes., Julie R Ingelfinger and Clifford J Rosen

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FSH and longitudinal changes in bone marrow adipose tissue composition in older adults, Tiffany Y. Kim, Trisha F. Hue, Susan K. Ewing, Xiaojuan Li, Sigurdur Sigurdsson, Vilmundur Gudnason, Annegreet G. Vlug, Deborah M. Kado, and Clifford J. Rosen

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Targeting FSH for osteoporosis, obesity, and Alzheimer's disease., Funda Korkmaz, Judit Gimenez-Roig, Farhath Sultana, Victoria Laurencin, Fasilet Sen, Liam Cullen, Steven Sims, Anusha Pallapati, Satish Rojekar, Guzel Burganova, Clifford J. Rosen, Tony Yuen, Se-Min Kim, and Mone Zaidi

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The role of bone in whole-body energy metabolism, Beata Lecka-Czernik, Clifford J. Rosen, and Nicola Napoli

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Evolution of temporomandibular joint reconstruction: from autologous tissue transplantation to alloplastic joint replacement, Hanghang Liu, Liwei Huang, Shibo Liu, Linyi Liu, and Bolun Li

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Weight loss induced bone loss: mechanism of action and clinical implications, Hanghang Liu, Bolun Li, Linyi Liu, Wangyang Ying, and Clifford J. Rosen

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Corrigendum to "Calorie restriction induces mandible bone loss by regulating mitochondrial function" [Bone 190 (2024) 117326]., Linyi Liu, Phuong T Le, Victoria E DeMambro, Tiange Feng, Hanghang Liu, Wangyang Ying, Roland Baron, and Clifford J Rosen

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Towards a consensus atlas of human and mouse adipose tissue at single-cell resolution., Anne Loft, Margo P Emont, Ada Weinstock, Adeline Divoux, Adhideb Ghosh, Allon Wagner, Matthew D Lynes, Rinki Murphy, Saeed Pirouzpanah, Silvia Corvera, Su'an Tang, Swapan K Das, Søren F Schmidt, Tao Zhang, Theodore M Nelson, Timothy E O'Sullivan, Vissarion Efthymiou, Wenjing Wang, Yihan Tong, Yu-Hua Tseng, Susanne Mandrup, and Evan D Rosen

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Short-term dietary methionine restriction with high fat diet counteracts metabolic dysfunction in male mice., Marissa I McGilvrey, Bethany Fortier, Diana Cooke, Maryam A Mahdi, Benjamin Tero, Christian M Potts, Abigail Kaija, Larisa Ryzhova, Carolina Cora, Adam Richardson, Douglas Guzior, Ilka Pinz, Calvin Vary, Robert A Koza, Gene Ables, and Lucy Liaw

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DIO3 coordinates photoreceptor development timing and fate stability in human retinal organoids, Christina McNerney, Clayton P. Santiago, Kiara C. Eldred, Ian Glass, Tom A. Reh, Arturo Hernandez, Seth Blackshaw, Nathan D. Lord, and Robert J. Johnston

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PTH counteracts Hippo signaling via Src-dependent YAP stabilization to enhance bone marrow stromal cell differentiation., Sara Monaci, Mengrui Wu, Hiroyuki Okada, Kedkanya Mesil, Byeong-Rak Keum, Maisa Monseff Rodrigues da Silva, Clifford J Rosen, Francesca Gori, and Roland Baron

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Human myocardial-derived highly proliferative cells improve cardiac remodeling after myocardial infarction in mice., Michayla Moore, Elena Chepurko, Vadim Chepurko, Calvin Vary, Sergey Ryzhov, and Douglas Sawyer

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Thermoneutral housing has limited effects on social isolation-induced bone loss in male C57BL/6J mice., Rebecca V Mountain, Rebecca L Peters, Audrie L Langlais, Julia Patrizia Stohn, Christine W Lary, and Katherine J Motyl

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Inhibition of acyl-CoA synthetase long-chain isozymes decreases multiple myeloma cell proliferation and causes mitochondrial dysfunction, Connor S. Murphy, Heather Fairfield, Victoria E. DeMambro, Samaa Fadel, Carlos A. Gartner, and Michelle Karam

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Non-Vesicular Extracellular Particle (NVEP) Proteomes from Diverse Biological Sources Reveal Specific Marker Composition with Varying Enrichment Levels., Wasifa Naushad, Bryson C Okeoma, Carlos Gartner, Yulica Santos-Ortega, Calvin P H Vary, Lakmini S Premadasa, Alessio Noghero, Jack T Stapleton, Ionita C Ghiran, Mahesh Mohan, and Chioma M Okeoma

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Circulating microRNA expression underlying the association of opioid use with low bone mineral density, Zannatun Nayema, Jennifer Spillane, Katherine J. Motyl, and Christine W. Lary

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Lipidomic and proteomic insights from extracellular vesicles in the postmortem dorsolateral prefrontal cortex reveal substance use disorder-induced brain changes, Chioma M. Okeoma, Wasifa Naushad, Bryson C. Okeoma, Carlos Gartner, and Yulica Santos-Ortega

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Monitoring Mouse Surface Temperature During Stress with a Thermal Camera: A Low-Cost Infrared Videography System for Evaluating Murine Metabolism., Breanna Page, Carolina Cora, James Reilly, Ryan Reno, Wadak Harbi, Maureen S Lynes, Michael A Lynes, and Matthew D Lynes

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Efficacy and safety of a therapeutic humanized FSH-blocking antibody in obesity and Alzheimer's disease models., Anusha R Pallapati, Funda Korkmaz, Satish Rojekar, Steven Sims, Anurag Misra, Judit Gimenez-Roig, Aishwarya Gangadhar, Victoria Laurencin, Anisa Gumerova, Uliana Cheliadinova, Farhath Sultana, Darya Vasilyeva, and Clifford J Rosen

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Vertical sleeve gastrectomy and semaglutide have distinct effects on skeletal health and heart function in obese male mice., Caroline de Carvalho Picoli, Sergey Tsibulnikov, Mavy Ho, Victoria DeMambro, Tiange Feng, May Eltahir, Phuong T Le, Carolyn Chlebek, Clifford J Rosen, Sergey Ryzhov, and Ziru Li

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Exploration of Conserved Human Adipose Subpopulations Using Targeted Single-Nuclei RNA Sequencing Data Sets., Christian M Potts, Xuehui Yang, Matthew D Lynes, Kimberly Malka, and Lucy Liaw

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NOTCH Signaling Networks in Perivascular Adipose Tissue., Christian Potts, Chenhao Yang, and Lucy Liaw

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Semaglutide for Type I Diabetes - A New Twist on an Old Story., Clifford J. Rosen

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A randomized, double-blind, placebo-controlled clinical study to evaluate the efficacy of the synbiotic medical food, SBD111, for the clinical dietary management of bone loss in menopausal women., Eric M Schott, Mark R Charbonneau, Douglas P Kiel, Susan Bukata, Michael J Zuscik, Clifford J. Rosen, and Alicia Ballok

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CTHRC1 Expression Results in Secretion-Mediated, SOX9-Dependent Suppression of Adipogenesis: Implications for the Regulatory Role of Newly Identified CTHRC1/PDGFR-Alpha Stromal Cells of Adipose, Matthew E. Siviski, Rachel Bercovitch, Kathleen Pyburn, Christian Potts, and Shivangi R. Pande

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Lyme Disease, Robert P Smith

The Bronchoalveolar Proteome Changes in Obesity, William G. Tharp, Carlos A. Gartner, Yulica Santos-Ortega, Calvin P. Vary, and S Patrick Bender

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The Bronchoalveolar Proteome Changes in Obesity, William G. Tharp, Carlos A. Gartner, Yulica Santos-Ortega, Calvin P. Vary, and S Patrick Bender

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Next-gen tools in cancer neuroscience., Vera Thiel, Debpali Sur, Caroline C Picoli, Tamara McErlain, and Katalina Couto

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Nuclear Condensates of WW Domain-Containing Adaptor With Coiled-Coil Regulate Mitophagy via Alternative Splicing., Jiahe Wang, Yi Fan, Guowen Luo, Liang Xiong, Lijie Wang, Zhuoxuan Wu, Jiayi Wang, Zhengying Peng, Clifford J. Rosen, Kefeng Lu, Junjun Jing, Quan Yuan, Zhenwei Zhang, and Chenchen Zhou

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Clinical Consequences of Disproportionate Free Valproate Elevation in Critically Ill Adult Patients: A Multicenter Retrospective Cohort Study., Andrew J Webb, David J Gagnon, Caitlin S Brown, Richard R. Riker, Natasha D Lopez, and Melanie Z Goodberlet

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Promotion of Cardiovascular Homeostasis by the Perivascular Adipose Tissue Secretome., Olivia R Whittaker, Matthew D Lynes, Ilka Pinz, and Lucy Liaw

Submissions from 2024

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Long Covid and Impaired Cognition - More Evidence and More Work to Do, Ziyad Al-Aly and Clifford J. Rosen

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Interindividual differences of dietary fat-inducible Mest in white adipose tissue of C57BL/6J mice are not heritable., Rea Victoria P Anunciado-Koza, Haifeng Yin, Crystal L Bilodeau, Diana Cooke, Gene P Ables, Sergey Ryzhov, and Robert A Koza

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Human Soluble Prorenin Receptor Expressed in Mouse Renal Collecting Duct Show Sex-Specific Effect on Cardiorenal Function, Gertrude Arthur, Audrey Poupeau, Katherine Biel, Jeffrey L. Osborn, Ming Gong, Terry D. Hinds, Volkhard Lindner, and Analia S. Loria

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Intestinal FGF15 regulates bile acid and cholesterol metabolism but not glucose and energy balance, Nadejda Bozadjieva-Kramer, Jae Hoon Shin, Ziru Li, Alan C. Rupp, and Nicole Miller

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Cytoplasmic retention of the DNA/RNA-binding protein FUS ameliorates organ fibrosis in mice, Manuel Chiusa, Youngmin A. Lee, Ming-Zhi Zhang, Raymond C. Harris, Taylor Sherrill, Volkhard Lindner, Craig R. Brooks, Gang Yu, Agnes B. Fogo, and Charles R. Flynn

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Cytoplasmic retention of the DNA/RNA-binding protein FUS ameliorates organ fibrosis in mice, Manuel Chiusa, Youngmin A. Lee, Ming-Zhi Zhang, Raymond C. Harris, Taylor Sherrill, Volkhard Lindner, Craig R. Brooks, Gang Yu, Agnes B. Fogo, and Charles R. Flynn

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In nondiabetic C57BL/6J mice, canagliflozin affects the skeleton in a sex- and age-dependent manner, Carolyn Chlebek, Casey McAndrews, Samantha N. Costa, Victoria E. DeMambro, Shoshana Yakar, and Clifford J. Rosen

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Delayed CCL23 response is associated with poor outcomes after cardiac arrest, Joanne T. deKay, Elena Chepurko, Vadim Chepurko, Lacey Knudsen, Christine Lord, Meghan Searight, Sergey Tsibulnikov, Richard R. Riker, and Douglas Sawyer

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Endothelial cells increase mesenchymal stem cell differentiation in scaffold-free 3D vascular tissue, William Gabriel DeMaria, Andre Figueroa-Milla, Abigail Kaija, Anne E. Harrington, Benjamin Tero, Larisa Ryzhova, and Lucy Liaw

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ScreenDMT reveals DiHOMEs are replicably inversely associated with BMI and stimulate adipocyte calcium influx, Jonathan M. Dreyfuss, Vera Djordjilović, Hui Pan, Valerie Bussberg, Allison M. MacDonald, Niven R. Narain, Michael A. Kiebish, Matthias Blüher, Yu-Hua Tseng, and Matthew D. Lynes

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Cellular Characteristics and Protein Signatures of Human Adipose Tissues from Donors With or Without Advanced Coronary Artery Disease, Caitlin P. Ellis, Benjamin W. Tero, Christian M. Potts, Kimberly T. Malka, Xuehui Yang, Joshua Hamilton, Calvin Vary, Andre Khalil, and Lucy Liaw

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Adipocytes and metabolism: Contributions to multiple myeloma, Heather Fairfield, Michelle Karam, Allyson Schimelman, Ya-Wei Qiang, and Michaela R. Reagan

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Exploratory Mass Spectrometry of Cerebrospinal Fluid from Persons with Autopsy-Confirmed LATE-NC, Jozsef Gal, Calvin Vary, Carlos A. Gartner, Gregory A. Jicha, Erin L. Abner, Yulica S. Ortega, Ibrahim Choucair, Donna M. Wilcock, Ruth S. Nelson, and Peter T. Nelson

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Navigating the Adipocyte Precursor Niche: Cell-Cell Interactions, Regulatory Mechanisms and Implications for Adipose Tissue Homeostasis, Devesh Kesharwani and Aaron C. Brown

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Neuroendocrinology of bone, Se-Min Kim, Farhath Sultana, Funda Korkmaz, Satish Rojekar, Anusha Pallapati, Vitaly Ryu, Daria Lizneva, Tony Yuen, and Clifford J. Rosen

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Brown fat ATP-citrate lyase links carbohydrate availability to thermogenesis and guards against metabolic stress, Ekaterina D. Korobkina, Camila Martinez Calejman, John A. Haley, Miranda E. Kelly, Huawei Li, Maria Gaughan, Qingbo Chen, and Matthew D. Lynes

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Pharmacogenetic and microRNA mechanisms of beta blocker use on bone, Christine W. Lary, Elizabeth J. Atkinson, Jennifer Spillane, Zannatun Nayema, Tyler A. Roy, Rebecca Peters, Griffin T. Scott, Hongyu Chen, Archana Nagarajan, Katherine J. Motyl, and Aaron C. Brown

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PTH and the Regulation of Mesenchymal Cells within the Bone Marrow Niche, Hanghang Liu, Linyi Liu, and Clifford J. Rosen

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Calorie restriction induces mandible bone loss by regulating mitochondrial function, Linyi Liu, Phuong T. Le, Victoria E. DeMambro, Tiange Feng, Hanghang Liu, and Clifford J. Rosen

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Calorie Restriction in Mice Impairs Cortical but not Trabecular Peak Bone Mass by Suppressing Bone Remodeling, Linyi Liu, Phuong T. Le, J Patrizia Stohn, Hanghang Liu, Wangyang Ying, Roland Baron, and Clifford J. Rosen

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NOISe: Nuclei-Aware Osteoclast Instance Segmentation for Mouse-to-Human Domain Transfer, Sai Kumar Manne, Brendan Martin, Tyler Roy, Ryan Neilson, Rebecca Peters, Meghana Chillara, Christine W. Lary, Katherine J. Motyl, and Michael Wan

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Transgenerational epigenetic self-memory of dosage is associated with methylation and altered growth trajectories and neonatal hormones, M Elena Martinez, Aldona Karaczyn, Zhaofei Wu, Christian A. Bennett, Kassey L. Matoin, Heather M. Daigle, and Arturo Hernandez

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Extracellular metallothionein as a therapeutic target in the early progression of Type 1 Diabetes, Clare K. Melchiorre, Matthew D. Lynes, Sadikshya Bhandari, Sheng-Chiang Su, Christian M. Potts, Amy V. Thees, Carol E. Norris, Lucy Liaw, Yu-Hua Tseng, and Michael A. Lynes

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ALK1 Signaling in Human Cardiac Progenitor Cells Promotes a Pro-angiogenic Secretome, Michayla Moore, Sergey Ryzhov, Douglas Sawyer, Carlos Gartner, and Calvin Vary

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Network analysis of brain and bone tissue transcripts reveals shared molecular mechanisms underlying Alzheimer's Disease and related dementias (ADRD) and Osteoporosis, Archana Nagarajan, Jason Laird, Obiadada Ugochukwu, Sjur Reppe, Kaare Gautvik, Ryan D. Ross, David A. Bennett, and Clifford J. Rosen

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Patients' Perspectives on Health-Related Social Needs and Recommendations for Interventions: A Qualitative Study, Tessa K. Novick, Michelle Osuna, Caroline Emery, Francisco Barrios, Daniel Ramirez, Deidra C. Crews, and Elizabeth Jacobs

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Endothelial IL17RD promotes Western diet-induced aortic myeloid cell infiltration, Shivangi Pande, Calvin Vary, Xuehui Yang, Lucy Liaw, Lindsey Gower, Robert Friesel, Igor Prudovsky, and Sergey Ryzhov

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Tranexamic acid reduces inflammation, edema and burn wound conversion in a rodent model, Igor Prudovsky, Doreen Kacer, Volkhard Lindner, Joseph Rappold, and Damien Wilson Carter

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Parallel control of cold-triggered adipocyte thermogenesis by UCP1 and CKB, Janane F. Rahbani, Jakub Bunk, Damien Lagarde, Bozena Samborska, Anna Roesler, Abhirup Shaw, Zafir Kaiser, Jessica L. Braun, Mia S. Geromella, and Robert A. Koza

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Viral Variants, Vaccinations, and Long Covid - New Insights., Clifford J Rosen