Submissions from 2025
Trends in Osteoporosis Drug Therapy Receipt Among Commercial and Medicare Advantage Enrollees in the United States, 2011-2022, Alexander O. Everhart, Juan P. Brito, Bart L. Clarke, Jeph Herrin, Pinar Karaca-Mandic, Kurt A. Kennel, and Clifford J. Rosen
Bone Marrow Adipocytes as Novel Regulators of Metabolic Homeostasis: Clinical Consequences of Bone Marrow Adiposity, Hanghang Liu, Linyi Liu, and Clifford J. Rosen
Submissions from 2024
Negative feedback between PTH1R and IGF1 through the Hedgehog pathway in mediating craniofacial bone remodeling, Yi Fan, Ping Lyu, Jiahe Wang, Yali Wei, Zucen Li, Shiwen Zhang, Takehito Ouchi, Junjun Jing, Quan Yuan, Chenchen Zhou, and Clifford J. Rosen
Prevalent Metformin Use in Adults With Diabetes and the Incidence of Long COVID: An EHR-Based Cohort Study From the RECOVER Program, Steven G. Johnson, Sajjad Abedian, Til Stürmer, Jared D. Huling, Colby Lewis V, and Clifford J. Rosen
Enhanced fatty acid oxidation in osteoprogenitor cells provides protection from high-fat diet induced bone dysfunction, Ananya Nandy, Ron C. Helderman, Santosh Thapa, Sun H. Peck, Alison Richards, Shobana Jayapalan, Nikita Narayani, Michael P. Czech, and Clifford J. Rosen
Liposomal bupivacaine in transversus abdominis plane blocks for lower abdominal surgery, Obiyo Osuchukwu, James Gagnon, Janelle Richard, Wendy Craig, and Aurora Quaye
Post-COVID-19: Hematological Factors Changes in Patients at Three-- time Intervals, Mohsen Sharifzak, Mojtaba Abbasi-Jorjandi, Gholamreza Asadikaram, Zohreh-Al-Sadat Ghoreshi, Moslem Abolhassani, and Clifford Rosen
Submissions from 2023
Changes in serum cortisol levels after 10 days of overfeeding and fasting, Caitlin Colling, Miriam A. Bredella, Pouneh K. Fazeli, Gisela Pachón-Peña, Ravinder J. Singh, Clifford J. Rosen, and Karen K. Miller
Assessing the effects of therapeutic combinations on SARS-CoV-2 infected patient outcomes: A big data approach, Hamidreza Moradi, H Timothy Bunnell, Bradley S. Price, Maryam Khodaverdi, Michael T. Vest, James Z. Porterfield, and Alfred J. Anzalone
Development and biophysical characterization of a humanized FSH-blocking monoclonal antibody therapeutic formulated at an ultra-high concentration, Satish Rojekar, Anusha R. Pallapati, Judit Gimenez-Roig, Funda Korkmaz, Farhath Sultana, Damini Sant, Clement M. Haeck, Anne Macdonald, Se-Min Kim, Clifford J. Rosen, Orly Barak, Marcia Meseck, John Caminis, Daria Lizneva, Tony Yuen, and Mone Zaidi
Long-term effects of canagliflozin treatment on the skeleton of aged UM-HET3 mice, Gozde Yildirim, Edmara T. Bergamo, Sher Bahadur Poudel, Ryan R. Ruff, Manisha Dixit, Bin Hu, Dindo Mijares, Lukasz Witek, Carolyn Chlebek, David Harrison, Randy Strong, Richard A. Miller, Warren Ladiges, Timothy G. Bromage, Clifford J. Rosen, and Shoshana Yaker
Submissions from 2022
Mouse mutagenesis and phenotyping to generate models of development and disease, Thomas Gridley and Stephen A. Murray
Submissions from 2020
Exploring mechanisms of increased cardiovascular disease risk with antipsychotic medications: Risperidone alters the cardiac proteomic signature in mice., Megan Beauchemin, Ramaz Geguchadze, Anyonya R Guntur, Kathleen Nevola, Phuong T Le, Deborah Barlow, Megan Rue, Calvin P H Vary, Christine W Lary, Katherine J Motyl, and Karen L Houseknecht
AGS and NIA Bench-to Bedside Conference Summary: Osteoporosis and Soft Tissue (Muscle and Fat) Disorders., Cathleen Colón-Emeric, Heather E Whitson, Sarah D Berry, Roger A Fielding, Denise K Houston, Douglas P Kiel, Clifford J Rosen, Kenneth L Seldeen, Elena Volpi, James P White, and Bruce R Troen
Marrow Adipocytes: Origin, Structure, and Function., Francisco J A de Paula and Clifford J Rosen
First-in-class humanized FSH blocking antibody targets bone and fat., Sakshi Gera, Damini Sant, Shozeb Haider, Funda Korkmaz, Tan-Chun Kuo, Mehr Mathew, Helena Perez-Pena, Honglin Xie, Hao Chen, Rogerio Batista, Kejun Ma, Zhen Cheng, Elina Hadelia, Cemre Robinson, Anne Macdonald, Sari Miyashita, Anthony Williams, Gregory Jebian, Hirotaka Miyashita, Anisa Gumerova, Kseniia Ievleva, Pinar Smith, Jiahuan He, Vitaly Ryu, Victoria DeMambro, Matthew A Quinn, Marcia Meseck, Se-Min Kim, T Rajendra Kumar, Jameel Iqbal, Maria I New, Daria Lizneva, Clifford J Rosen, Aaron J Hsueh, Tony Yuen, and Mone Zaidi
The Lipid Handling Capacity of Subcutaneous Fat Is Programmed by mTORC2 during Development., Wen-Yu Hsiao, Su Myung Jung, Yuefeng Tang, John A Haley, Rui Li, Huawei Li, Camila Martinez Calejman, Joan Sanchez-Gurmaches, Chien-Min Hung, Amelia K Luciano, Victoria DeMambro, Kathryn E Wellen, Clifford J Rosen, Lihua Julie Zhu, and David A Guertin
Finerenone - Halting Relative Hyperaldosteronism in Chronic Kidney Disease., Julie R Ingelfinger and Clifford J Rosen
Editorial: Bone Marrow Adiposity: Establishing Harmonized, Mechanistic, and Multidisciplinary Approaches to Reach Clinical Translation., Stephanie Lucas, Clifford James Rosen, and Nathalie Bravenboer
Bariatric Surgery and Restoration of Insulin Sensitivity - It's Weight Loss., Clifford J Rosen and Julie R Ingelfinger
Submissions from 2019
The effect of raloxifene on bone marrow adipose tissue and bone turnover in postmenopausal women with osteoporosis., Kerensa M Beekman, Annegreet G Veldhuis-Vlug, Martin den Heijer, Mario Maas, Ania M Oleksik, Michael W Tanck, Susan M Ott, Rob J van 't Hof, Paul Lips, Peter H Bisschop, and Nathalie Bravenboer
Therapeutic Irradiation: Consequences for Bone and Bone Marrow Adipose Tissue., Samantha Costa and Michaela R Reagan
Association of Receiving Multiple, Concurrent Fracture-Associated Drugs With Hip Fracture Risk., Rebecca T Emeny, Chiang-Hua Chang, Jonathan Skinner, A James O'Malley, Jeremy Smith, Gouri Chakraborti, Clifford J Rosen, and Nancy E Morden
The mitophagy receptor Bcl-2-like protein 13 stimulates adipogenesis by regulating mitochondrial oxidative phosphorylation and apoptosis in mice., Makoto Fujiwara, Li Tian, Phuong T Le, Victoria E DeMambro, Kathleen A Becker, Clifford J Rosen, and Anyonya R Guntur
Functional analysis of monocarboxylate transporter 8 mutations in Japanese Allan-Herndon-Dudley syndrome patients., Mohammad Saiful Islam, Noriyuki Namba, Yasuhisa Ohata, Makoto Fujiwara, Chiho Nakano, Shinji Takeyari, Kei Miyata, Yukako Nakano, Kenichi Yamamoto, Hirofumi Nakayama, Taichi Kitaoka, Takuo Kubota, and Keiichi Ozono
A novel mouse model overexpressing Nocturnin results in decreased fat mass in male mice., Phuong T Le, Sheila A Bornstein, Katherine J Motyl, Li Tian, Jeremy J Stubblefield, Hee-Kyung Hong, Joseph S Takahashi, Carla B Green, Clifford J Rosen, and Anyonya R Guntur
Per- and Polyfluoroalkyl Substances and Bone Mineral Density in Mid-childhood, Shravanthi M. Seshasayee, Rachel Cluett, Lisa B. Rokoff, Sheryl L. Rifas-Shiman, Diane R. Gold, Brent Coull, Catherine M. Gordon, Clifford J. Rosen, Emily Oken, Sharon K. Sagiv, and Abby F. Fleisch
Adult onset of type 3 deiodinase deficiency in mice alters brain gene expression and increases locomotor activity., J Patrizia Stohn, M Elena Martinez, Donald L St Germain, and Arturo Hernandez
Submissions from 2018
High fat diet attenuates hyperglycemia, body composition changes, and bone loss in male streptozotocin-induced type 1 diabetic mice., Adriana Lelis Carvalho, Victoria E DeMambro, Anyonya R Guntur, Phuong Le, Kenichi Nagano, Roland Baron, Francisco José Albuquerque de Paula, and Katherine J Motyl
The skeletal cell-derived molecule sclerostin drives bone marrow adipogenesis., Heather Fairfield, Carolyne Falank, Elizabeth Harris, Victoria Demambro, Michelle McDonald, Jessica A Pettitt, Sindhu T Mohanty, Peter Croucher, Ina Kramer, Michaela Kneissel, Clifford J Rosen, and Michaela R Reagan
Changes in marrow adipose tissue with short-term changes in weight in premenopausal women with anorexia nervosa., Pouneh K Fazeli, Alex Faje, Miriam A Bredella, Sai Polineni, Stephen Russell, Megi Resulaj, Clifford J Rosen, and Anne Klibanski
Sexual Dimorphism and the Origins of Human Spinal Health., Vicente Gilsanz, Tishya A L Wren, Skorn Ponrartana, Stefano Mora, and Clifford J Rosen
Osteoblast-like MC3T3-E1 Cells Prefer Glycolysis for ATP Production but Adipocyte-like 3T3-L1 Cells Prefer Oxidative Phosphorylation., Anyonya R Guntur, Akos A Gerencser, Phuong T Le, Victoria E DeMambro, Sheila A Bornstein, Shona A Mookerjee, David E Maridas, David E Clemmons, Martin D Brand, and Clifford J Rosen
Epitope-specific monoclonal antibodies to FSHβ increase bone mass., Yaoting Ji, Peng Liu, Tony Yuen, Shozeb Haider, Jiahuan He, Raquel Romero, Hao Chen, Madison Bloch, Se-Min Kim, Daria Lizneva, Lubna Munshi, Chunxue Zhou, Ping Lu, Jameel Iqbal, Zhen Cheng, Maria I New, Aaron J Hsueh, Zhuan Bian, Clifford J Rosen, Li Sun, and Mone Zaidi
Clinical implications of bone marrow adiposity., A G Veldhuis-Vlug and C J Rosen
Submissions from 2017
High fat diet attenuates hyperglycemia, body composition changes, and bone loss in male streptozotocin-induced type 1 diabetic mice., Adriana Lelis Carvalho, Victoria E DeMambro, Anyonya R Guntur, Phuong Le, Kenichi Nagano, Roland Baron, Francisco José Albuquerque de Paula, and Katherine J Motyl
Structure and function of bone marrow adipocytes., Francisco José Albuquerque de Paula and Clifford J. Rosen
Bone marrow adipocytes., Mark C Horowitz, Ryan Berry, Brandon Holtrup, Zachary Sebo, Tracy Nelson, Jackie A Fretz, Dieter Lindskog, Jennifer L Kaplan, Gene Ables, Matthew S Rodeheffer, and Clifford J Rosen
A novel role for dopamine signaling in the pathogenesis of bone loss from the atypical antipsychotic drug risperidone in female mice., Katherine J Motyl, Megan Beauchemin, Deborah Barlow, Phuong T Le, Kenichi Nagano, Annika Treyball, Anisha Contractor, Roland Baron, Clifford J Rosen, and Karen L Houseknecht
Energy metabolism of bone., Katherine J Motyl, Anyonya R Guntur, Adriana Lelis Carvalho, and Clifford J Rosen
New insights into fuel choices of nephron progenitor cells., Leif Oxburgh and Clifford J Rosen
A perspective on malignancy in the marrow., Michaela R Reagan, Jane B Lian, Clifford J Rosen, and Gary S Stein
Cover image, volume 232, number 12, December 2017., Michaela R Reagan, Jane B Lian, Clifford J Rosen, and Gary S Stein
Intracellular lipid droplets support osteoblast function., Elizabeth Rendina-Ruedy, Anyonya R Guntur, and Clifford J Rosen
An essential role for IGF2 in cartilage development and glucose metabolism during postnatal long bone growth., Tomoya Uchimura, Judith M Hollander, Daisy S Nakamura, Zhiyi Liu, Clifford J. Rosen, Irene Georgakoudi, and Li Zeng
Submissions from 2016
HP1BP3 expression determines maternal behavior and offspring survival., B P Garfinkel, S Arad, S M Neuner, S Netser, S Wagner, C C Kaczorowski, C J. Rosen, M Gal, H Soreq, and J Orly
Cardiac and renovascular complications in type 2 diabetes--is there hope?, Julie R. Ingelfinger and Clifford J. Rosen
Building better bones with biologics - a new approach to osteoporosis?, Clifford J Rosen and Julie R Ingelfinger
Type 2 diabetes and the skeleton: new insights into sweet bones., Vikram V Shanbhogue, Deborah M Mitchell, Clifford J Rosen, and Mary L Bouxsein
Submissions from 2015
A high fat diet increases bone marrow adipose tissue (MAT) but does not alter trabecular or cortical bone mass in C57BL/6J mice., Casey R Doucette, Mark C Horowitz, Ryan Berry, Ormond A MacDougald, Rea Anunciado-Koza, Robert A Koza, and Clifford J Rosen
Proportionate dwarfism in mice lacking heterochromatin protein 1 binding protein 3 (HP1BP3) is associated with alterations in the endocrine IGF-1 pathway., Benjamin P Garfinkel, Shiri Arad, Phuong T Le, Michael Bustin, Clifford J Rosen, Yankel Gabet, and Joseph Orly
PTHrp comes full circle in cancer biology., Anyonya R Guntur, Casey R Doucette, and Clifford J Rosen
Cardiovascular risk and sodium-glucose cotransporter 2 inhibition in type 2 diabetes., Julie R Ingelfinger and Clifford J Rosen
Energy excess, glucose utilization, and skeletal remodeling: new insights., Beata Lecka-Czernik and Clifford J Rosen
Propranolol attenuates risperidone-induced trabecular bone loss in female mice., Katherine J Motyl, Victoria E DeMambro, Deborah Barlow, David Olshan, Kenichi Nagano, Roland Baron, Clifford J Rosen, and Karen L Houseknecht
Region-specific variation in the properties of skeletal adipocytes reveals regulated and constitutive marrow adipose tissues., Erica L Scheller, Casey R Doucette, Brian S Learman, William P Cawthorn, Shaima Khandaker, Benjamin Schell, Brent Wu, Shi-Ying Ding, Miriam A Bredella, Pouneh K Fazeli, Basma Khoury, Karl J Jepsen, Paul F Pilch, Anne Klibanski, Clifford J Rosen, and Ormond A MacDougald
Questions about vitamin D for primary care practice: input from an NIH conference., Christine L Taylor, Paul R Thomas, John F Aloia, Peter S Millard, and Clifford J Rosen
Submissions from 2014
Bioenergetics during calvarial osteoblast differentiation reflect strain differences in bone mass., Anyonya R Guntur, Phuong T Le, Charles R Farber, and Clifford J Rosen
Retinaldehyde dehydrogenase 1 deficiency inhibits PPARγ-mediated bone loss and marrow adiposity., Shriram Nallamshetty, Phuong T Le, Hong Wang, Maya J Issacsohn, David J Reeder, Eun-Jung Rhee, Florian W Kiefer, Jonathan D Brown, Clifford J Rosen, and Jorge Plutzky
The epidemiology and pathogenesis of osteoporosis., Clifford J. Rosen
Submissions from 2013
IGF-1 regulation of key signaling pathways in bone., Anyonya R Guntur and Clifford J Rosen
Altered thermogenesis and impaired bone remodeling in Misty mice., Katherine J Motyl, Kathleen A Bishop, Victoria E DeMambro, Sheila A Bornstein, Phuong Le, Masanobu Kawai, Sutada Lotinun, Mark C Horowitz, Roland Baron, Mary L Bouxsein, and Clifford J Rosen
Submissions from 2012
Bone as an endocrine organ., Anyonya R Guntur and Clifford J Rosen
A high-fat diet induces bone loss in mice lacking the Alox5 gene., Phuong Le, Masanobu Kawai, Sheila Bornstein, Victoria E DeMambro, Mark C Horowitz, and Clifford J Rosen
Submissions from 2011
An essential role for the circadian-regulated gene nocturnin in osteogenesis: the importance of local timekeeping in skeletal homeostasis., Anyonya R Guntur, Masanobu Kawai, Phuong Le, Mary L Bouxsein, Sheila Bornstein, Carla B Green, and Clifford J Rosen
The skeleton: a multi-functional complex organ: new insights into osteoblasts and their role in bone formation: the central role of PI3Kinase., Anyonya R Guntur and Clifford J Rosen
Emerging therapeutic opportunities for skeletal restoration., Masanobu Kawai, Ulrike I Mödder, Sundeep Khosla, and Clifford J Rosen
Pediatric obesity: a review for the child psychiatrist., Ann E Maloney
Temperatures rising: brown fat and bone., Katherine J Motyl and Clifford J Rosen
Submissions from 2010
Back to the future: revisiting parathyroid hormone and calcitonin control of bone remodeling., F J A de Paula and C J Rosen
Novel insights into the relationship between diabetes and osteoporosis., Francisco J A de Paula, Mark C Horowitz, and Clifford J Rosen
Minireview: A skeleton in serotonin's closet?, Masanobu Kawai and Clifford J Rosen
PPARγ: a circadian transcription factor in adipogenesis and osteogenesis., Masanobu Kawai and Clifford J Rosen
The IGF-I regulatory system and its impact on skeletal and energy homeostasis., Masanobu Kawai and Clifford J Rosen
Pediatric obesity: a review for the child psychiatrist., Ann E Maloney