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Submissions from 2017

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Bone marrow stroma and vascular contributions to myeloma bone homing., Michele Moschetta, Yawara Kawano, Antonio Sacco, Angelo Belotti, Rossella Ribolla, Marco Chiarini, Viviana Giustini, Diego Bertoli, Alessandra Sottini, Monica Valotti, Claudia Ghidini, Federico Serana, Michele Malagola, Luisa Imberti, Domenico Russo, Alessandro Montanelli, Giuseppe Rossi, Michaela R Reagan, Patricia Maiso, Bruno Paiva, Irene M Ghobrial, and Aldo M Roccaro

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Novel nomogram combining depth of invasion and size can accurately predict the risk for regional nodal metastases for appendiceal neuroendocrine tumors (A-NET)., Catalina Mosquera, Timothy L Fitzgerald, Haily Vora, and Marysia Grzybowski

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A novel role for dopamine signaling in the pathogenesis of bone loss from the atypical antipsychotic drug risperidone in female mice., Katherine J Motyl, Megan Beauchemin, Deborah Barlow, Phuong T Le, Kenichi Nagano, Annika Treyball, Anisha Contractor, Roland Baron, Clifford J Rosen, and Karen L Houseknecht

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Energy metabolism of bone., Katherine J Motyl, Anyonya R Guntur, Adriana Lelis Carvalho, and Clifford J Rosen

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Screening for behavioral health conditions in primary care settings: a systematic review of the literature., Norah Mulvaney-Day, Tina Marshall, Kathryn Downey Piscopo, Neil Korsen, Sean Lynch, Lucy H Karnell, Garrett E Moran, Allen S Daniels, and Sushmita Shoma Ghose

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Deletion of the thyroid hormone-activating type 2 deiodinase rescues cone photoreceptor degeneration but not deafness in mice lacking type 3 deiodinase., Lily Ng, Hong Liu, Donald L St Germain, Arturo Hernandez, and Douglas Forrest

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Improving Type And Screen Specimen Collection Prior To Elective Surgery, NorDx Blood Bank Staff, Haley Pelletier, Suneela Nayak, Stephen Tyzik, and Ruth Hanselman

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A prospective evaluation of the candle wax sign: a visual clue to diagnose aggressive basal cell carcinoma., Brian Patrick O'Donnell and Christine W Duarte

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Growth factor regulation in the nephrogenic zone of the developing kidney., Leif Oxburgh, Sree Deepthi Muthukrishnan, and Aaron Brown

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New insights into fuel choices of nephron progenitor cells., Leif Oxburgh and Clifford J Rosen

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Identification Strategies For The Very High Fall Risk Patient In An Acute Inpatient Psychiatric Unit, P6 Inpatient Geri-Med Psychiatry, Haley Pelletier, Suneela Nayak, Stephen Tyzik, and Ruth Hanselman

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Increased utilization of cervical disk arthroplasty in university hospitals with regional variation and socioeconomic discrepancies., Sheri K Palejwala, Anand I Rughani, and Travis M Dumont

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Sensory characteristics of youth at clinical high risk for psychosis., L Diane Parham, Sean Roush, Donna T Downing, Paul G Michael, and William R McFarlane

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Effects of neuregulin GGF2 (cimaglermin alfa) dose and treatment frequency on left ventricular function in rats following myocardial infarction., Tom J Parry, Anindita Ganguly, Erika L Troy, J Luis Guerrero, Jennifer F Iaci, Maya Srinivas, Andrea M Vecchione, Donald C Button, Craig S Hackett, Ronald Zolty, Douglas B Sawyer, and Anthony O Caggiano

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Cefepime-induced neurotoxicity: a systematic review., Lauren E Payne, David J Gagnon, Richard R Riker, David B Seder, Elizabeth K Glisic, Jane G Morris, and Gilles L Fraser

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Using quality improvement tools to reduce chronic lung disease., Alan Peter Picarillo and Waldemar Carlo

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A new tool to tackle the opioid epidemic: description, utility, and results from the Maine Diversion Alert Program., Brian J Piper, Clare E Desrosiers, Harriet C Fisher, Kenneth L McCall, and Stephanie D Nichols

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Healthcare policy and urologic practice., Daniel Pitts and Jesse D Sammon

Dose-Dependent and Lasting Influences of Intranasal Vasopressin on Face Processing in Men., Daniel Price, Debra Burris, Anna Cloutier, Carol B Thompson, James K Rilling, and Richmond R Thompson

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Dose-dependent and lasting influences of intranasal vasopressin on face processing in men., Daniel Price, Debra Burris, Anna Cloutier, Carol B Thompson, James K Rilling, and Richmond R Thompson

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Low bone density and bisphosphonate use and the risk of kidney stones., Megan Prochaska, Eric Taylor, Anand Vaidya, and Gary Curhan

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Patient Fall Prevention, R9 West Cardiovascular, Cathy Palleschi, Suneela Nayak, Ruth Hanselman, and Stephen Tyzik

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"Choosing Wisely" imaging recommendations: initial implementation in New England emergency departments., Ali S Raja, Arjun K Venkatesh, Nathan Mick, Cristopher P Zabbo, Kohei Hasegawa, Janice A Espinola, Jane C Bittner, and Carlos A Camargo

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Emergency neurological life support: airway, ventilation, and sedation., Venkatakrishna Rajajee, Becky Riggs, and David B. Seder

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Patient-reported outcome metrics in total joint arthroplasty., Adam Rana and Shaleen Vira

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Editors' preface., Joseph F Rappold and Philip C Spinella

The bioengineering core, Michaela Reagan

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A perspective on malignancy in the marrow., Michaela R Reagan, Jane B Lian, Clifford J Rosen, and Gary S Stein

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Cover image, volume 232, number 12, December 2017., Michaela R Reagan, Jane B Lian, Clifford J Rosen, and Gary S Stein

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Clinical reasoning education at US medical schools: results from a national survey of internal medicine clerkship directors., Joseph Rencic, Robert L Trowbridge, Mark Fagan, Karen Szauter, and Steven Durning

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Intracellular lipid droplets support osteoblast function., Elizabeth Rendina-Ruedy, Anyonya R Guntur, and Clifford J Rosen

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Bone-fat interaction., Elizabeth Rendina-Ruedy and Clifford J Rosen

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Valproate protein binding is highly variable in ICU patients and not predicted by total serum concentrations: a case series and literature review., Richard R Riker, David J Gagnon, Colman Hatton, Teresa May, David B Seder, Katie Stokem, and Gilles L Fraser

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Caution warranted regarding transfusion for subarachnoid hemorrhage., Richard R Riker and David B Seder

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The most important lessons I learned in training., Michael P Robich

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Analysis of "never events" following adult cardiac surgical procedures in the United States., Michael P Robich, Brianna M Krafcik, Nishant K Shah, Alik Farber, Denis Rybin, and Jeffrey J Siracuse

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Real-time H2 O2 measurements in bone marrow mesenchymal stem cells (MSCs) show increased antioxidant capacity in cells from osteoporotic women., Flavia Román, Carla Urra, Omar Porras, Ana María Pino, Clifford J. Rosen, and Juan Pablo Rodríguez

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Education in nephrology fellowship: a survey-based needs assessment., Robert W Rope, Kurtis A Pivert, Mark G Parker, Stephen M Sozio, and Sylvia Bereknyei Merell

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Romosozumab - promising or practice changing?, Clifford J Rosen

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ERBB signaling attenuates proinflammatory activation of nonclassical monocytes., Sergey Ryzhov, Anton Matafonov, Cristi L Galindo, Qinkun Zhang, Truc-Linh Tran, Daniel J Lenihan, Carrie Geisberg Lenneman, Igor Feoktistov, and Douglas B Sawyer

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The airway in inhalational injury: diagnosis and management., A Sabri, H Dabbous, A Dowli, and R Barazi

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A novel in vivo model for studying conditional dual loss of BLIMP-1 and p53 in B-cells, leading to tumor transformation., Antonio Sacco, Yawara Kawano, Michele Moschetta, Oksana Zavidij, Daisy Huynh, Michaela Reagan, Yuji Mishima, Salomon Manier, Jihye Park, Elizabeth Morgan, Satoshi Takagi, Kwok K Wong, Ruben Carrasco, Irene M Ghobrial, and Aldo M Roccaro

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Airway management and mechanical ventilation in acute brain injury., D B Seder and J Bösel

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Effect of adjunct femoral endarterectomy in lower extremity bypass on perioperative and 1-year outcomes., Peter A Soden, Sara L Zettervall, Katie E Shean, Sarah E Deery, Jeffrey A Kalish, Christopher T. Healey, Nikhil Kansal, Marc L Schermerhorn, and Vascular Study Group of New England (VSGNE)

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A systematic review of transition studies of pulmonary arterial hypertension specific medications., Avraham Sofer, Michael J Ryan, Ryan J Tedford, Joel A Wirth, and Wassim H Fares

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MicroRNA transfer between bone marrow adipose and multiple myeloma cells., Luna Soley, Carolyne Falank, and Michaela R Reagan

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Increased number of circulating CD8/CD26 T cells in the blood of Duchenne muscular dystrophy patients is associated with augmented binding of adenosine deaminase and higher muscular strength scores., Jonathan H Soslow, Larry W Markham, W Bryan Burnette, Cristi L Galindo, Igor Feoktistov, Frank J Raucci, Bruce M Damon, Douglas B. Sawyer, and Sergey Ryzhov

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Subcutaneous injection of testosterone is an effective and preferred alternative to intramuscular injection: demonstration in female-to-male transgender patients., Daniel I Spratt, India I Stewart, Clara Savage, Wendy Craig, Norman P Spack, Donald Walt Chandler, Lindsey V Spratt, Toni Eimicke, and Jerrold S Olshan

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Medical humanities: Using MedHum to promote the goal of professional identity in UME, Michael P.H. Stanley

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Higher maternal protein intake during pregnancy is associated with lower cord blood concentrations of insulin-like growth factor (IGF)-II, IGF binding protein 3, and insulin, but not IGF-I, in a cohort of women with high protein intake., Karen M Switkowski, Paul F Jacques, Aviva Must, Marie-France Hivert, Abby Fleisch, Matthew W Gillman, Sheryl Rifas-Shiman, and Emily Oken

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Adverse reaction to metal debris with concomitant incidental crystalline arthropathy in hip arthroplasty., Edward J Testa and Brian J McGrory

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Strategies To Improve Interdisciplinary Communication In An Acute Care Inpatient Pediatric Unit, Sarah Thompson; Haley Pelletier; Barbara Bush Children's Hospital-Inpatient, Maine Medical Center; Suneela Nayak; Ruth Hanselman; and Stephen Tyzik

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Guidelines for family-centered care in neuro-ICU populations: caveats for routine palliative care., Michel T Torbey, Gretchen M Brophy, Panayiotis N Varelas, Julian Bösel, Edward Manno, Mary Kay Bader, Jose I Suarez, David Seder, and W David Freeman

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Factor analysis of the scale of prodromal symptoms: data from the early detection and intervention for the prevention of psychosis program., Ivy F Tso, Stephan F Taylor, Tyler B Grove, Tara Niendam, Steven Adelsheim, Andrea Auther, Barbara Cornblatt, Cameron S Carter, Roderick Calkins, J Daniel Ragland, Tamara Sale, and William R McFarlane

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An essential role for IGF2 in cartilage development and glucose metabolism during postnatal long bone growth., Tomoya Uchimura, Judith M Hollander, Daisy S Nakamura, Zhiyi Liu, Clifford J. Rosen, Irene Georgakoudi, and Li Zeng

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An evaluation of the opportunities for collaborative practice occurring in and the impact of interprofessional education on advanced pharmacy practice experiences., Elena M Umland, Jonathan Valenzano, Caitlin Brown, and Carolyn Giordano

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Body size and the risk of primary hyperparathyroidism in women: a cohort study., Anand Vaidya, Gary C Curhan, Julie M Paik, Molin Wang, and Eric N Taylor

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Mechanisms of marrow adiposity and its implications for skeletal health., Annegreet G Veldhuis-Vlug and Clifford J Rosen

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Impact of non-medical out-of-pocket expenses on families of children with cerebral palsy following orthopaedic surgery., Judith A Vessey, Rachel L DiFazio, Tania D Strout, and Brian D Snyder

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Pioglitazone and risk for bone fracture: safety data from a randomized clinical trial., Catherine M Viscoli, Silvio E Inzucchi, Lawrence H Young, Karl L Insogna, Robin Conwit, Karen L Furie, Mark Gorman, Michael A Kelly, Anne M Lovejoy, and Walter N Kernan

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Adolescent female with abdominal pain., Diane Walsh, Rebecca B Bloch, and Tania D Strout

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Bim expression in endothelial cells and pericytes is essential for regression of the fetal ocular vasculature., Shoujian Wang, Ismail S Zaitoun, Ryan P Johnson, Nasim Jamali, Zafer Gurel, Catherine M Wintheiser, Andreas Strasser, Volkhard Lindner, Nader Sheibani, and Christine M Sorenson

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First-trimester chorionic bump--association with fetal aneuploidy in a high-risk population., Joseph R Wax, Angelina Cartin, Christian Litton, Michael G Pinette, and F L Lucas

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Cervical evaluation in pregnancy: proper measurement, evaluation, and management., Joseph R Wax, Angelina Cartin, and Michael G Pinette

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Clinical pitfalls in misoprostol-based medical management of first-trimester induced and presumed spontaneous abortion., Joseph R. Wax, Kelley Conroy, Michael G. Pinette, Christian Litton, and Angelina Cartin

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The effect of anticoagulation on bleeding-related complications following ureteroscopy., Mary E Westerman, Joseph A Scales, Vidit Sharma, Derek J Gearman, Johann P Ingimarsson, and Amy E Krambeck

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Tacrolimus interaction with nafcillin resulting in significant decreases in tacrolimus concentrations: a case report., Minkey Wungwattana and Marizela Savic

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Type 3 deiodinase role on central thyroid hormone action affects the leptin-melanocortin system and circadian activity., Zhaofei Wu, M Elena Martinez, Donald L St Germain, and Arturo Hernandez

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The need for optimized crystalloid-based resuscitation., Avi Yitzhak, Yuval Glick, Avi Benov, Roy Nadler, Joseph F Rappold, and Elon Glassberg

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Cardiac outcomes after ischemic stroke or transient ischemic attack: effects of pioglitazone in patients with insulin resistance without diabetes mellitus., Lawrence H Young, Catherine M Viscoli, Jeptha P Curtis, Silvio E Inzucchi, Gregory G Schwartz, Anne M Lovejoy, Karen L Furie, Mark J Gorman, Robin Conwit, J Dawn Abbott, Daniel L Jacoby, Daniel M Kolansky, Steven E Pfau, Frederick S Ling, and Walter N Kernan

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Low-dose prothrombin complex concentrate for warfarin-associated intracranial hemorrhage with INR less than 2.0., Wesley R Zemrak, Kathryn E Smith, Stephen S Rolfe, Teresa May, Robert L Trowbridge, Timothy L Hayes, Gene A Grindlinger, and David B Seder

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Cardiovascular risk in survivors of cancer., Henry Chen Zheng, Laura Onderko, and Sanjeev A Francis

Submissions from 2016

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Carbonic anhydrase IX is a marker of hypoxia and correlates with higher Gleason scores and ISUP grading in prostate cancer., Maria Raffaella Ambrosio, Claudia Di Serio, Giovanna Danza, Bruno Jim Rocca, Alessandro Ginori, Igor Prudovsky, Niccolò Marchionni, Maria Teresa Del Vecchio, and Francesca Tarantini

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Identification of an endogenously generated cryptic collagen epitope (XL313) that may selectively regulate angiogenesis by an integrin Yes-associated protein (YAP) mechano-transduction pathway, Jacquelyn J Ames, Liangru Contois, Jennifer M Caron, Eric Tweedie, Xuehui Yang, Robert Friesel, Calvin Vary, and Peter C Brooks

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Molecular correlates of fat mass expansion in C57BL/6J mice after short-term exposure to dietary fat., Rea P Anunciado-Koza, Justin Manuel, and Robert A Koza

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The role of clinical nurse specialists in the implementation and sustainability of a practice change., Rhonda L Babine, Cindy Honess, Heidi R Wierman, and Sarah Hallen

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Clinafloxacin for treatment of Burkholderia cenocepacia infection in a cystic fibrosis patient, Akshu Balwan, David P Nicolau, Minkey Wungwattana, Jonathan B Zuckerman, and Valerie Waters

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Fine-tuning of Notch signaling sets the boundary of the organ of Corti and establishes sensory cell fates., Martin L Basch, Rogers M Brown, Hsin-I Jen, Fatih Semerci, Frederic Depreux, Renée K Edlund, Hongyuan Zhang, Christine R Norton, Thomas Gridley, Susan E Cole, Angelika Doetzlhofer, Mirjana Maletic-Savatic, Neil Segil, and Andrew K Groves

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Preface., Lisa T. Beaule and Moritz H. Hansen

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Diagnosis and surgical management of male pelvic, inguinal, and testicular pain., Gabriel V. Belanger and Graham T. VerLee

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The Vascular Quality Initiative Cardiac Risk Index for prediction of myocardial infarction after vascular surgery., Daniel J Bertges, Dan Neal, Andres Schanzer, Salvatore T Scali, Philip P Goodney, Jens Eldrup-Jorgensen, and Jack L Cronenwett

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Getting the SCOOP-survey of cardiovascular outcomes from oncology patients during survivorship., Nirmanmoh Bhatia, Daniel Lenihan, Douglas B. Sawyer, and Carrie G Lenneman

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Organizing graduate medical education programs into communities of practice., Robert G Bing-You and Kalli Varaklis

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Unknown risks: parental hesitation about vaccination., Laura L Blaisdell, Caitlin Gutheil, Norbert A M Hootsmans, and Paul K J Han

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The National Children's Study: recruitment outcomes using an enhanced household-based approach., Laura L. Blaisdell, Jennifer A Zellner, Alison A King, Elaine Faustman, Mari Wilhelm, Mark L Hudak, and Robert D Annett

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Network analysis implicates Alpha-Synuclein (Snca) in the regulation of ovariectomy-Induced bone loss., Gina Calabrese, Larry D Mesner, Patricia L Foley, Clifford J. Rosen, and Charles R Farber

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Discovery of novel small molecule inhibitors of VEGF expression in tumor cells using a cell-based high throughput screening platform., Liangxian Cao, Marla Weetall, Jenelle Bombard, Hongyan Qi, Tamil Arasu, William Lennox, Jean Hedrick, Josephine Sheedy, Nicole Risher, Peter C Brooks, Panayiota Trifillis, Christopher Trotta, Young-Choon Moon, John Babiak, Neil G Almstead, Joseph M Colacino, Thomas W Davis, and Stuart W Peltz

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Does bathing frequency matter in pediatric atopic dermatitis?, Ivan D. Cardona, Leland Stillman, and Neal Jain

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Inhibition of ovarian tumor growth by targeting the HU177 cryptic collagen epitope., Jennifer M M. Caron, Jacquelyn J. Ames, Liangru Contois, Leonard Liebes, Robert Friesel, Franco Muggia, Calvin PH Vary, Leif Oxburgh, and Peter C Brooks

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Conflicting health information: a critical research need., Delesha M Carpenter, Lorie L Geryk, Annie T Chen, Rebekah H Nagler, Nathan F Dieckmann, and Paul K J Han

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Results of the Nellix system investigational device exemption pivotal trial for endovascular aneurysm sealing., Jeffrey P Carpenter, Robert Cuff, Clifford Buckley, Christopher Healey, Sajjad Hussain, Michel M P J Reijnen, Jose Trani, and Dittmar Böckler

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Personalized prediction of psychosis: external validation of the NAPLS-2 psychosis risk calculator with the EDIPPP Project., Ricardo E Carrión, Barbara A Cornblatt, Cynthia Z Burton, Ivy F Tso, Andrea M Auther, Steven Adelsheim, Roderick Calkins, Cameron S Carter, Tara Niendam, Tamara G Sale, Stephan F Taylor, and William R. McFarlane

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Managing the patient with pulmonary hypertension: specialty care centers, coordinated care, and patient support., Murali M Chakinala, Maribeth Duncan, and Joel Wirth

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Pediatric urology for the general surgeon., David J. Chalmers and Vijaya M Vemulakonda

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Inter-rater reliability of the APD, SFU and UTD grading systems in fetal sonography and MRI., D J. Chalmers, M L Meyers, K E Brodie, C Palmer, and J B Campbell

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Nonvitamin K anticoagulant agents in patients with advanced chronic kidney disease or on dialysis with AF., Kevin E Chan, Robert P Giugliano, Manesh R Patel, Stuart Abramson, Meg Jardine, Sophia Zhao, Vlado Perkovic, Franklin W Maddux, and Jonathan P Piccini

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Genetic counseling for patients considering screening and diagnosis for chromosomal abnormalities., Renée L. Chard and Mary E Norton

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A twelve-year consecutive case experience in thoracic reconstruction., Jenny T Chen, Laura A Bonneau, Tracey L. Weigel, James D Maloney, Francisco Castro, Nikita Shulzhenko, and Michael L Bentz

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IDH2 mutations define a unique subtype of breast cancer with altered nuclear polarity., Sarah Chiang, Britta Weigelt, Huei-Chi Wen, Fresia Pareja, Ashwini Raghavendra, Luciano G Martelotto, Kathleen A Burke, Thais Basili, Anqi Li, Felipe C Geyer, Salvatore Piscuoglio, Charlotte K Y Ng, Achim A Jungbluth, Jörg Balss, Stefan Pusch, Gabrielle M Baker, Kimberly S Cole, Andreas von Deimling, Julie M Batten, Jonathan D Marotti, Hwei-Choo Soh, Benjamin L McCalip, Jonathan Serrano, Raymond S Lim, Kalliopi P Siziopikou, Song Lu, Xiaolong Liu, Tarek Hammour, Edi Brogi, Matija Snuderl, A John Iafrate, Jorge S Reis-Filho, and Stuart J Schnitt

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A multistate model predicting mortality, length of stay, and readmission for surgical patients., David E Clark, Kaitlin R Ostrander, and Brad M Cushing