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Submissions from 2016

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Carbonic anhydrase IX is a marker of hypoxia and correlates with higher Gleason scores and ISUP grading in prostate cancer., Maria Raffaella Ambrosio, Claudia Di Serio, Giovanna Danza, Bruno Jim Rocca, Alessandro Ginori, Igor Prudovsky, Niccolò Marchionni, Maria Teresa Del Vecchio, and Francesca Tarantini

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Identification of an endogenously generated cryptic collagen epitope (XL313) that may selectively regulate angiogenesis by an integrin Yes-associated protein (YAP) mechano-transduction pathway, Jacquelyn J Ames, Liangru Contois, Jennifer M Caron, Eric Tweedie, Xuehui Yang, Robert Friesel, Calvin Vary, and Peter C Brooks

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Molecular correlates of fat mass expansion in C57BL/6J mice after short-term exposure to dietary fat., Rea P Anunciado-Koza, Justin Manuel, and Robert A Koza

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The role of clinical nurse specialists in the implementation and sustainability of a practice change., Rhonda L Babine, Cindy Honess, Heidi R Wierman, and Sarah Hallen

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Clinafloxacin for treatment of Burkholderia cenocepacia infection in a cystic fibrosis patient, Akshu Balwan, David P Nicolau, Minkey Wungwattana, Jonathan B Zuckerman, and Valerie Waters

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Fine-tuning of Notch signaling sets the boundary of the organ of Corti and establishes sensory cell fates., Martin L Basch, Rogers M Brown, Hsin-I Jen, Fatih Semerci, Frederic Depreux, Renée K Edlund, Hongyuan Zhang, Christine R Norton, Thomas Gridley, Susan E Cole, Angelika Doetzlhofer, Mirjana Maletic-Savatic, Neil Segil, and Andrew K Groves

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Preface., Lisa T. Beaule and Moritz H. Hansen

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Diagnosis and surgical management of male pelvic, inguinal, and testicular pain., Gabriel V. Belanger and Graham T. VerLee

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The Vascular Quality Initiative Cardiac Risk Index for prediction of myocardial infarction after vascular surgery., Daniel J Bertges, Dan Neal, Andres Schanzer, Salvatore T Scali, Philip P Goodney, Jens Eldrup-Jorgensen, and Jack L Cronenwett

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Getting the SCOOP-survey of cardiovascular outcomes from oncology patients during survivorship., Nirmanmoh Bhatia, Daniel Lenihan, Douglas B. Sawyer, and Carrie G Lenneman

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Organizing graduate medical education programs into communities of practice., Robert G Bing-You and Kalli Varaklis

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Unknown risks: parental hesitation about vaccination., Laura L Blaisdell, Caitlin Gutheil, Norbert A M Hootsmans, and Paul K J Han

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The National Children's Study: recruitment outcomes using an enhanced household-based approach., Laura L. Blaisdell, Jennifer A Zellner, Alison A King, Elaine Faustman, Mari Wilhelm, Mark L Hudak, and Robert D Annett

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Network analysis implicates Alpha-Synuclein (Snca) in the regulation of ovariectomy-Induced bone loss., Gina Calabrese, Larry D Mesner, Patricia L Foley, Clifford J. Rosen, and Charles R Farber

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Discovery of novel small molecule inhibitors of VEGF expression in tumor cells using a cell-based high throughput screening platform., Liangxian Cao, Marla Weetall, Jenelle Bombard, Hongyan Qi, Tamil Arasu, William Lennox, Jean Hedrick, Josephine Sheedy, Nicole Risher, Peter C Brooks, Panayiota Trifillis, Christopher Trotta, Young-Choon Moon, John Babiak, Neil G Almstead, Joseph M Colacino, Thomas W Davis, and Stuart W Peltz

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Does bathing frequency matter in pediatric atopic dermatitis?, Ivan D. Cardona, Leland Stillman, and Neal Jain

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Inhibition of ovarian tumor growth by targeting the HU177 cryptic collagen epitope., Jennifer M M. Caron, Jacquelyn J. Ames, Liangru Contois, Leonard Liebes, Robert Friesel, Franco Muggia, Calvin PH Vary, Leif Oxburgh, and Peter C Brooks

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Conflicting health information: a critical research need., Delesha M Carpenter, Lorie L Geryk, Annie T Chen, Rebekah H Nagler, Nathan F Dieckmann, and Paul K J Han

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Results of the Nellix system investigational device exemption pivotal trial for endovascular aneurysm sealing., Jeffrey P Carpenter, Robert Cuff, Clifford Buckley, Christopher Healey, Sajjad Hussain, Michel M P J Reijnen, Jose Trani, and Dittmar Böckler

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Personalized prediction of psychosis: external validation of the NAPLS-2 psychosis risk calculator with the EDIPPP Project., Ricardo E Carrión, Barbara A Cornblatt, Cynthia Z Burton, Ivy F Tso, Andrea M Auther, Steven Adelsheim, Roderick Calkins, Cameron S Carter, Tara Niendam, Tamara G Sale, Stephan F Taylor, and William R. McFarlane

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Managing the patient with pulmonary hypertension: specialty care centers, coordinated care, and patient support., Murali M Chakinala, Maribeth Duncan, and Joel Wirth

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Pediatric urology for the general surgeon., David J. Chalmers and Vijaya M Vemulakonda

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Inter-rater reliability of the APD, SFU and UTD grading systems in fetal sonography and MRI., D J. Chalmers, M L Meyers, K E Brodie, C Palmer, and J B Campbell

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Nonvitamin K anticoagulant agents in patients with advanced chronic kidney disease or on dialysis with AF., Kevin E Chan, Robert P Giugliano, Manesh R Patel, Stuart Abramson, Meg Jardine, Sophia Zhao, Vlado Perkovic, Franklin W Maddux, and Jonathan P Piccini

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Genetic counseling for patients considering screening and diagnosis for chromosomal abnormalities., Renée L. Chard and Mary E Norton

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A twelve-year consecutive case experience in thoracic reconstruction., Jenny T Chen, Laura A Bonneau, Tracey L. Weigel, James D Maloney, Francisco Castro, Nikita Shulzhenko, and Michael L Bentz

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IDH2 mutations define a unique subtype of breast cancer with altered nuclear polarity., Sarah Chiang, Britta Weigelt, Huei-Chi Wen, Fresia Pareja, Ashwini Raghavendra, Luciano G Martelotto, Kathleen A Burke, Thais Basili, Anqi Li, Felipe C Geyer, Salvatore Piscuoglio, Charlotte K Y Ng, Achim A Jungbluth, Jörg Balss, Stefan Pusch, Gabrielle M Baker, Kimberly S Cole, Andreas von Deimling, Julie M Batten, Jonathan D Marotti, Hwei-Choo Soh, Benjamin L McCalip, Jonathan Serrano, Raymond S Lim, Kalliopi P Siziopikou, Song Lu, Xiaolong Liu, Tarek Hammour, Edi Brogi, Matija Snuderl, A John Iafrate, Jorge S Reis-Filho, and Stuart J Schnitt

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A multistate model predicting mortality, length of stay, and readmission for surgical patients., David E Clark, Kaitlin R Ostrander, and Brad M Cushing

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Clinical and research considerations for patients with hypertensive acute heart failure: a consensus statement from the Society for Academic Emergency Medicine and the Heart Failure Society of America Acute Heart Failure Working Group., Sean P Collins, Phillip D Levy, Jennifer L Martindale, Mark E Dunlap, Alan B Storrow, Peter S Pang, Nancy M Albert, G Michael Felker, Gregory J Fermann, Gregg C Fonarow, Michael M Givertz, Judd E Hollander, David E Lanfear, Daniel J Lenihan, JoAnn M Lindenfeld, W Frank Peacock, Douglas B. Sawyer, John R Teerlink, and Javed Butler

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Clinical and research considerations for patients with hypertensive acute heart failure: a consensus statement from the Society of Academic Emergency Medicine and the Heart Failure Society of America Acute Heart Failure Working Group., Sean P Collins, Phillip D Levy, Jennifer L Martindale, Mark E Dunlap, Alan B Storrow, Peter S Pang, Nancy M Albert, G Michael Felker, Gregory J Fermann, Gregg C Fonarow, Michael M Givertz, Judd E Hollander, David J Lanfear, Daniel J Lenihan, JoAnn M Lindenfeld, W Frank Peacock, Douglas B. Sawyer, John R Teerlink, and Javed Butler

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Tissue-engineered 3D cancer-in-bone modeling: silk and PUR protocols., Ushashi Dadwal, Carolyne Falank, Heather Fairfield, Sarah Linehan, Clifford J Rosen, David L Kaplan, Julie Sterling, and Michaela R Reagan

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Determinants of prostate specific antigen screening among black men in the United States in the contemporary era., Deepansh Dalela, Firas Abdollah, Toni K Choueiri, Paul K Han, Moritz Hansen, Paul L Nguyen, Akshay Sood, Mani Menon, Quoc-Dien Trinh, and Jesse Sammon

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American Telemedicine Association guidelines for TeleICU operations., Theresa M Davis, Connie Barden, Steve Dean, Amnon Gavish, Irene Goliash, Susan Goran, Andrew Graley, Pat Herr, William Jackson, Edward Loo, James P Marcin, John Morgan Morris, David E Morledge, Carol Olff, Teresa Rincon, Stephanie Rogers, Herb Rogove, Rebecca Rufo, Elizabeth Thomas, Marc T Zubrow, Elizabeth A Krupinski, and Jordana Bernard

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Intended and unintended consequences of constraining clinician prescribing: the case of antipsychotics., John W Devlin, Pamela Smithburger, Jason M Kane, Gilles L. Fraser, and Yoanna Skrobik

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Daily leptin blunts marrow fat but does not impact bone mass in calorie-restricted mice., M J Devlin, D J Brooks, C Conlon, M van Vliet, L Louis, C J. Rosen, and M L Bouxsein

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Electronic records, registries, and the development of "big data": crowd-sourcing quality toward knowledge., Summer B Dewdney and Jason Lachance

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Type 2 diabetes and aging: a not so sweet scenario for bone., R Dhaliwal and C J Rosen

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The rheology of subarachnoid hemorrhage., Robert D Ecker

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Early debris formation with a porous tantalum glenoid component: radiographic analysis with 2-year minimum follow-up., Donald P. Endrizzi, Johanna A. Mackenzie, and Patrick D G Henry

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A blown pupil and intracranial hemorrhage in a 4-week-old: a case of delayed onset vitamin K deficiency bleeding, a rare "can't miss" diagnosis., Ryley Enz and Robert S. Anderson Jr

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Signaling interplay between bone marrow adipose tissue and multiple myeloma cells., Carolyne Falank, Heather Fairfield, and Michaela R. Reagan

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miR-199b, a novel tumor suppressor miRNA in acute myeloid leukemia with prognostic implications., Amanda J Favreau, Rose E McGlauflin, Christine W Duarte, and Pradeep Sathyanarayana

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Novel biological therapies targeting heart failure: myocardial rejuvenation., Amanda J. Favreau-Lessard, Sergey Ryzhov, and Douglas B. Sawyer

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Total, Dietary, and Supplemental Vitamin C Intake and Risk of Incident Kidney Stones., Pietro Manuel Ferraro, Gary C Curhan, Giovanni Gambaro, and Eric N Taylor

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Dietary protein and potassium, diet-dependent net acid load, and risk of incident kidney stones., Pietro Manuel Ferraro, Ernest I Mandel, Gary C Curhan, Giovanni Gambaro, and Eric N. Taylor

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Collaborative care and integration: changing roles and changing Identity of the child and adolescent psychiatrist?, Sandra L. Fritsch, Abigail Schlesinger, Amy D Habeger, Barry Sarvet, and Joyce N Harrison

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Heterogeneity of Psychosis Risk Within Individuals at Clinical High Risk: A Meta-analytical Stratification., Paolo Fusar-Poli, Marco Cappucciati, Stefan Borgwardt, Scott W Woods, Jean Addington, Barnaby Nelson, Dorien H Nieman, Daniel R Stahl, Grazia Rutigliano, Anita Riecher-Rössler, Andor E Simon, Masafumi Mizuno, Tae Young Lee, Jun Soo Kwon, May M L Lam, Jesus Perez, Szabolcs Keri, Paul Amminger, Sibylle Metzler, Wolfram Kawohl, Wulf Rössler, Jimmy Lee, Javier Labad, Tim Ziermans, Suk Kyoon An, Chen-Chung Liu, Kristen A Woodberry, Amel Braham, Cheryl Corcoran, Patrick McGorry, Alison R Yung, and Philip K McGuire

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HP1BP3 expression determines maternal behavior and offspring survival., B P Garfinkel, S Arad, S M Neuner, S Netser, S Wagner, C C Kaczorowski, C J. Rosen, M Gal, H Soreq, and J Orly

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Medication-related self-management behaviors among arthritis patients: does attentional coping style matter?, Lorie L Geryk, Susan J Blalock, Robert F DeVellis, Joanne M Jordan, Paul K J Han, and Delesha M Carpenter

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Premeasured chordal loops for mitral valve repair., Marc Gillinov, Reed Quinn, Faraz Kerendi, Vince Gaudiani, Richard Shemin, Glenn Barnhart, Edward Raines, Marc W Gerdisch, and Michael Banbury

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The cost and outcome effectiveness of total hip replacement: technique choice and volume-output effects matter., Jonathan P Goldstein, George M. Babikian, Adam J. Rana, Johanna A. Mackenzie, and Andrew Millar

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Pneumonia prevention in intubated patients given sucralfate versus proton-pump inhibitors and/or histamine II receptor blockers., Gene A Grindlinger, Sarah B Cairo, and Carole B Duperre

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Decompressive craniectomy for severe traumatic brain injury: clinical study, literature review and meta-analysis., Gene A. Grindlinger, David H. Skavdahl, Robert D. Ecker, and Matthew R. Sanborn

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Shared decision-making as an existential journey: aiming for restored autonomous capacity., Pål Gulbrandsen, Marla L Clayman, Mary Catherine Beach, Paul K. Han, Emily F Boss, Eirik H Ofstad, and Glyn Elwyn

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Development and evaluation of the "BRISK Scale," a brief observational measure of risk communication competence., Paul K J Han, Katherine Joekes, Greg Mills, Caitlin Gutheil, Kahsi Smith, Nancy E Cochran, and Glyn Elwyn

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The use of bowel in urologic reconstructive surgery., Moritz H. Hansen, Matthew Hayn, and Patrick Murray

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New insights into bone marrow adipocytes: report from the First European Meeting on Bone Marrow Adiposity (BMA 2015)., Pierre Hardouin, Pierre J Marie, and Clifford J Rosen

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New insights into bone marrow adipocytes: report from the first European meeting on bone marrow adiposity (BMA 2015)., Pierre Hardouin, Pierre J Marie, and Clifford J Rosen

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New insights into bone marrow adipocytes: report from the first European meeting on bone marrow adiposity (BMA 2015)., Pierre Hardouin, Pierre J Marie, and Clifford J. Rosen

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Free serum valproate concentration more reliable than total concentration in critically ill patients., Colman Hatton, Richard R. Riker, David J. Gagnon, Teresa May, David B. Seder, and Gilles L. Fraser

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Intensive point-of-care ultrasound training with long-term follow-up in a cohort of Rwandan physicians., Patricia C Henwood, David C. Mackenzie, Joshua S Rempell, Emily Douglass, Damas Dukundane, Andrew S Liteplo, Megan M Leo, Alice F Murray, Samuel Vaillancourt, Anthony J Dean, Resa E Lewiss, Stephen Rulisa, Elizabeth Krebs, A K Raja Rao, Emmanuel Rudakemwa, Vincent Rusanganwa, Patrick Kyanmanywa, and Vicki E Noble

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Knowledge and values for cancer screening decisions: results from a national survey., Richard M Hoffman, Joann G Elmore, Michael P Pignone, Bethany S Gerstein, Carrie A Levin, and Kathleen M Fairfield

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Cardiac and renovascular complications in type 2 diabetes--is there hope?, Julie R. Ingelfinger and Clifford J. Rosen

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Circulating vascular endothelial growth factor and the risk of cardiovascular events., Bernhard M Kaess, Sarah R Preis, Alexa Beiser, Douglas B. Sawyer, Tai C Chen, Sudha Seshadri, and Ramachandran S Vasan

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Genetic risk factors for the development of osteonecrosis in children under age 10 treated for acute lymphoblastic leukemia., Seth E Karol, Leonard A Mattano, Wenjian Yang, Kelly W Maloney, Colton Smith, ChengCheng Liu, Laura B Ramsey, Christian A Fernandez, Tamara Y Chang, Geoffrey Neale, Cheng Cheng, Elaine Mardis, Robert Fulton, Paul Scheet, F Anthony San Lucas, Eric C Larsen, Mignon L Loh, Elizabeth A Raetz, Stephen P Hunger, Meenakshi Devidas, and Mary V Relling

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Prognosis driven rehabilitation after rotator cuff repair surgery., Dirk Kokmeyer, Eric Dube, and Peter J Millett

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Closed mitral commissurotomy during pregnancy in East Africa., Robert Kramer, Reed Quinn, Agneta Odera, Robert Groom, Nancy Boulanger, Eric Gunnoe, and Russell White

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Regulation of glucose handling by the skeleton: insights from mouse and human studies., Jian-Min Liu, Clifford J Rosen, Patricia Ducy, Stavroula Kousteni, and Gerard Karsenty

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DMP-1-mediated Ghr gene recombination compromises skeletal development and impairs skeletal response to intermittent PTH., Zhongbo Liu, Oran D Kennedy, Luis Cardoso, Jelena Basta-Pljakic, Nicola C Partridge, Mitchell B Schaffler, Clifford J Rosen, and Shoshana Yakar

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RAS/MAPK activation Is associated with reduced tumor-infiltrating lymphocytes in triple-negative breast cancer: therapeutic cooperation between MEK and PD-1/PD-L1 immune checkpoint inhibitors., Sherene Loi, Sathana Dushyanthen, Paul A Beavis, Roberto Salgado, Carsten Denkert, Peter Savas, Susan Combs, David L Rimm, Jennifer M Giltnane, Monica V Estrada, Violeta Sánchez, Melinda E Sanders, Rebecca S Cook, Mark A Pilkinton, Simon A Mallal, Kai Wang, Vincent A Miller, Phil J Stephens, Roman Yelensky, Franco D Doimi, Henry Gómez, Sergey V Ryzhov, Phillip K Darcy, Carlos L Arteaga, and Justin M Balko

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A prospective randomized study of the efficacy of "Turning Point," an inpatient violence intervention program., Catherine Loveland-Jones, Lucas Ferrer, Scott Charles, Frederick Ramsey, Andrea van Zandt, Jill Volgraf, Thomas Santora, Abhijit Pathak, Jay Dujon, Lars Sjoholm, Joseph Rappold, and Amy Goldberg

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Urologic emergencies., Adam E. Ludvigson and Lisa T. Beaule

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Vitamin D deficiency - is there really a pandemic?, JoAnn E Manson, Patsy M Brannon, Clifford J Rosen, and Christine L Taylor

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Genomic imprinting of DIO3, a candidate gene for the syndrome associated with human uniparental disomy of chromosome 14., Maria Elena Martinez, David F. Cox, Brian P. Youth, and Arturo Hernandez

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Development of the Emotion Dysregulation Inventory: a PROMIS®ing method for creating sensitive and unbiased questionnaires for autism spectrum disorder., Carla A Mazefsky, Taylor N Day, Matthew Siegel, Susan W White, Lan Yu, and Paul A Pilkonis

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Diagnosis and management of lower urinary tract dysfunction., Robert C. McDonough and Stephen T. Ryan

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Family interventions for schizophrenia and the psychoses: a review., William R. McFarlane

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Surgical management of osteoarthritis of the knee: evidence-based guideline., Brian J J. McGrory, Kristy L Weber, David S Jevsevar, and Kaitlyn Sevarino

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Characterization of fatty acid composition in bone marrow fluid from postmenopausal women: modification after hip fracture., Melissa Miranda, Ana María Pino, Karen Fuenzalida, Clifford J. Rosen, Germán Seitz, and J Pablo Rodríguez

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Transfer of acute care surgery patients in a rural state: a concerning trend., Brittany Misercola, Kristen Sihler, Molly Douglas, Stephen Ranney, and Jonathan Dreifus

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Peripheral atherectomy: applications and techniques., Derek Mittleider and Erich Russell

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Randomized phase II evaluation of bevacizumab versus bevacizumab plus fosbretabulin in recurrent ovarian, tubal, or peritoneal carcinoma: an NRG Oncology/Gynecologic Oncology Group study., Bradley J Monk, Michael W Sill, Joan L Walker, Christopher J. Darus, Gregory Sutton, Krishnansu S Tewari, Lainie P Martin, Jeanne M Schilder, Robert L Coleman, Jai Balkissoon, and Carol Aghajanian

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A case of possible iatrogenic ketamine-Induced mania in a patient being treated for postoperative pain., Stephanie D. Nichols, Maya Bulman, Annya Tisher, and John J. Campbell

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Gender incongruity in children with and without disorders of sexual differentiation., Jerrold Olshan, Toni Eimicke, and Erin Belfort

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Difference in effectiveness of medication adherence intervention by health literacy level., Ashli A Owen-Smith, David H Smith, Cynthia S Rand, Jeffrey O Tom, Reesa Laws, Amy Waterbury, Andrew Williams, and William M Vollmer

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Pediatric surgery as an essential component of global child health., Doruk Ozgediz, Monica Langer, Phyllis Kisa, and Dan Poenaru

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MLLT11/AF1q boosts oncogenic STAT3 activity through Src-PDGFR tyrosine kinase signaling., Jino Park, Soojin Kim, Joongho Joh, Scot C. Remick, Donald M Miller, Jun Yan, Zeyad Kanaan, Ju-Hsien Chao, Maxwell M Krem, Soumit K Basu, Shotaro Hagiwara, Lukas Kenner, Richard Moriggl, Kevin D Bunting, and William Tse

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Multimodal Eph/Ephrin signaling controls several phases of urogenital development., Christiane Peuckert, Bejan Aresh, Pavlo Holenya, Derek Adams, Smitha Sreedharan, Annika Porthin, Louise Andersson, Hanna Pettersson, Stefan Wölfl, Rüdiger Klein, Leif Oxburgh, and Klas Kullander

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Qualitative aspects of bone marrow adiposity in osteoporosis., Ana María Pino, Melissa Miranda, Carolina Figueroa, Juan Pablo Rodríguez, and Clifford J Rosen

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Use and misuse of opioids in Maine: results from pharmacists, the prescription monitoring, and the diversion alert programs., Brian J Piper, Clare E Desrosiers, John W Lipovsky, Matthew A Rodney, Robert P Baker, Kenneth L McCall, Stephanie D. Nichols, and Sarah L Martin

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Colorectal carcinoma in pediatric patients: A comparison with adult tumors, treatment and outcomes from the National Cancer Database., Gabriela C Poles, David E Clark, Sara W Mayo, Elizabeth A Beierle, Melanie Goldfarb, Kenneth W Gow, Adam Goldin, John J Doski, Jed G Nuchtern, Sanjeev A Vasudevan, and Monica Langer

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Insights Into nephrolithiasis from the Nurses' Health Studies., Megan L Prochaska, Eric N. Taylor, and Gary C Curhan

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Targeting EPO and EPO receptor pathways in anemia and dysregulated erythropoiesis., Nicole Rainville, Edward Jachimowicz, and Don M Wojchowski

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Building a patient-reported outcome metric database: one hospital's experience., Adam J. Rana

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Methodological considerations when studying the skeletal response to glucose intolerance using the diet-induced obesity model., Elizabeth Rendina-Ruedy and Brenda J Smith

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Geographic access to interventional cardiology services in one rural state., James P Rhudy, Anne W Alexandrov, Kristiina E Hyrkäs, Rita A Jablonski-Jaudon, Erica R Pryor, Henry E Wang, and Marie A Bakitas

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Sedation quality in intensive care: which interventions work?, Richard R. Riker and Gilles L. Fraser

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Implementation of a simplistic bivalirudin-warfarin transition protocol Is associated with improved achievement of INR values within the therapeutic range., Amber R Rollins, Kathryn E Smith, and Wesley R Zemrak

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Building better bones with biologics - a new approach to osteoporosis?, Clifford J Rosen and Julie R Ingelfinger

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Prostate cancer: radiotherapy might improve survival, even in the oldest men., Stephen T. Ryan and Jesse D. Sammon