Incorporated in 1868, MMC is the state’s largest medical center, licensed for 700 beds and employing more than 9,600 people. MaineHealth Maine Medical Center’s unique role as both a community hospital and a referral center requires an unparalleled depth and breadth of services, including the state’s only allopathic medical school program, through a partnership with Tufts University School of Medicine, and a world-class biomedical research center, the MaineHealth Institute for Research.

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Submissions from 2025

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Modified Versions of Natural Frozen Embryo Transfers Do Not Impact Live Births, Courtney Hargreaves, Wendy Craig, Denny Sakkas, Thomas L. Toth, and Denis Vaughan

Pneumomastia: A Rare but Benign Mammographic Finding, Krucial Styslinger and Christina Cinelli

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Mobile Phone Auscultation Accurately Diagnoses Chronic Obstructive Pulmonary Disease Using Nonlinear Respiratory Biofluid Dynamics, Caroline Emily Gosser, Luther Daniel, Martin Huecker, Rodrigo Cavallazzi, Hiram Rivas, Jarred Jeremy Thomas, and Ryan Close

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Altered metabolomics and inflammatory transcriptomics in human bone marrow adipocytes after acute high calorie diet and acute fasting, Samantha N. Costa, Gisela Pachón-Peña, Julie Dragon, Scott Tighe, and Calvin Vary

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Evaluating community engagement efforts in a clinical and translational research initiative., Kelly Finck Waters, Brenda Joly, Carolyn E Gray, Jan K Carney, and Kathleen M Fairfield

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Embracing Compassion for People Facing Lung Cancer-the American Cancer Society National Lung Cancer Roundtable, Jamie L. Studts, Lisa Carter-Bawa, Jill Feldman, Joan H. Schiller, and Elizabeth Scharnetzki

Embracing Compassion for People Facing Lung Cancer-the American Cancer Society National Lung Cancer Roundtable, Jamie L. Studts, Lisa Carter-Bawa, Jill Feldman, Joan H. Schiller, and Elizabeth Scharnetzki

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Lessons learned: enhancing rural risk communication for future health crises through the PHERCC framework., Abimbola Leslie, Elizabeth K Woods, Eline M van den Broek-Altenburg, Gary S Stein, and Jan K Carney

A Case of a Portuguese Man-O-War Envenomation in Southern Rhode Island, Sean Bilodeau, Teresa Howard, and Alexis S. Kearney

A Case of a Portuguese Man-O-War Envenomation in Southern Rhode Island, Sean Bilodeau, Teresa Howard, and Alexis S. Kearney

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A Case of a Portuguese Man-O-War Envenomation in Southern Rhode Island, Sean Bilodeau, Teresa Howard, and Alexis S. Kearney

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Addiction Consultation and Medications for Substance Use Disorders Associated with Reduced 30-Day Readmission Rates, Michael Tozier MD

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Guanfacine for the management of the behavioral manifestations of delirium in older hospitalized adults., Kayla Garvey, Kobi Griffith, Emily Carter, Wendy Craig, David J Gagnon, Richard Riker, and Nicolette Centanni

The importance of the anterior nasal spine in predicting soft tissue movement in maxillary orthognathic surgery, Kehan Li, Wingyan Chow, Zhaokun Zhu, Liwei Huang, and Yao Liu

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The importance of the anterior nasal spine in predicting soft tissue movement in maxillary orthognathic surgery, Kehan Li, Wingyan Chow, Zhaokun Zhu, Liwei Huang, Yao Liu, and Hanghang Liu

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Adult Long Coronavirus Disease 2019: Definition, Prevalence Pathophysiology, and Clinical Manifestations., Ivette Emery and Clifford J. Rosen

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Cardiac Foreign Body, Joshua Rehberg, Alexander Lange, and David C. Mackenzie

"It's hard to talk to a computer, I get it": An exploratory analysis of clinician connection-building communication practices in rural telepalliative care encounters, Elise C. Tarbi

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NOTCH Signaling Networks in Perivascular Adipose Tissue., Christian Potts, Chenhao Yang, and Lucy Liaw

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Phantom Limb Pain Assessment Tools: A Literature Review Exploring Strengths and Limitations, Alexandra N. Jenson, Benjamin Branch, Janelle M. Richard, and Aurora Quaye

Pneumomastia: A Rare but Benign Mammographic Finding, Krucial Styslinger and Christina Cinelli

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Screening for Early Emerging Mental Experiences: Feasibility of Psychosis Screening in Integrated Care Settings., Kristen A Woodberry, Elizabeth Bernier, Katherine M Elacqua, David M Weiss, Stacey M Ouellette, Jonathan Fanburg, Deborah Q Hagler, Kathleen A Herlihy, Paul L Hyman, Rebecca B Jaynes, Saras Yerlig, and Amy M Mayhew

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Short-term dietary methionine restriction with high fat diet counteracts metabolic dysfunction in male mice., Marissa I McGilvrey, Bethany Fortier, Diana Cooke, Maryam A Mahdi, Benjamin Tero, Christian M Potts, Abigail Kaija, Larisa Ryzhova, Carolina Cora, Adam Richardson, Douglas Guzior, Ilka Pinz, Calvin Vary, Robert A Koza, Gene Ables, and Lucy Liaw

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The Anterior-Based Muscle-Sparing Approach for Conversion Total Hip Arthroplasty is Safe and Effective., Catherine M Call, Johanna Mackenzie, Zoë A Walsh, Bailey Shevenell, George Babikian, Brian J. McGrory, and Adam Rana

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The implementation of an electronic symptom management system to monitor postoperative pain in thoracic surgery patients: A multicenter evaluation, Jorind Beqari, Jacob Hurd, Angela C. Tramontano, Christine Cronin, Alexandra Potter, and Jessica Bian

The implementation of an electronic symptom management system to monitor postoperative pain in thoracic surgery patients: A multicenter evaluation, Jorind Beqari, Jacob Hurd, Angela C. Tramontano, Christine Cronin, Alexandra Potter, and Jessica Bian

Impact of Physiological Stress and Reserve on the Cost of Care: Operative Stress Score and Frailty, Timothy L. Fitzgerald, Laura Nicolais, Aurora Quaye, Janelle M. Richard, and Peter Hubbs

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Impact of Physiological Stress and Reserve on the Cost of Care: Operative Stress Score and Frailty, Timothy L. Fitzgerald, Laura Nicolais, Aurora Quaye, Janelle M. Richard, and Peter Hubbs

The Bronchoalveolar Proteome Changes in Obesity, William G. Tharp, Carlos A. Gartner, Yulica Santos-Ortega, Calvin P. Vary, and S Patrick Bender

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The Bronchoalveolar Proteome Changes in Obesity, William G. Tharp, Carlos A. Gartner, Yulica Santos-Ortega, Calvin P. Vary, and S Patrick Bender

The Bronchoalveolar Proteome Changes in Obesity, William G. Tharp, Carlos A. Gartner, Yulica Santos-Ortega, Calvin P. Vary, and S Patrick Bender

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Efficacy of stochastic vibro-tactile stimulation for newborns at risk of neonatal opioid withdrawal syndrome, Rachana Singh, Ludovic Trinquart, Benjamin Koethe, Mario Cordova, Lawrence Rhein, Shawana Bibi, Jamie Fey, Ariana Anderson, and Jonathan M. Davis

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Ethical Management of Challenging Behaviors in Hospitalized People Who Use Drugs, Christina Yen, Kinna Thakarar, and Tim Lahey

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Perioperative management of patients taking glucagon-like peptide 1 receptor agonists: Society for Perioperative Assessment and Quality Improvement (SPAQI) multidisciplinary consensus statement, Adriana D. Oprea, Laura J. Ostapenko, BobbieJean Sweitzer, Angela Selzer, Joan M. Irizarry-Alvarado, Maria D. Hurtado Andrade, Carlos E. Mendez, Kristen D. Kelley, Erin Stewart, Claudia R. Fernandez Robles, Ryan M. Chadha, Michael Camilleri, Ruchi Mathur, and Guillermo E. Umpierrez

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Safety and efficacy of pegtibatinase enzyme replacement therapy in adults with classical homocystinuria in the COMPOSE® phase 1/2 randomized trial, Can Ficicioglu, Janet A. Thomas, Jaya Ganesh, David Kudrow, Melissa Lah, Wendy E. Smith, Jalé Güner, Sharon McDermott, Sagar A. Vaidya, Liz Wilkening, and Harvey L. Levy

Early-life and concurrent predictors of the healthy adolescent microbiome in a cohort study, Hannah E. Laue, Amy D. Willis, Fang Wang, Melinda C. MacDougall, Yingying Xu, Margaret R. Karagas, Juliette C. Madan, Abby F. Fleisch, and Bruce P. Lanphear

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Early-life and concurrent predictors of the healthy adolescent microbiome in a cohort study, Hannah E. Laue, Amy D. Willis, Fang Wang, Melinda C. MacDougall, Yingying Xu, Margaret R. Karagas, Juliette C. Madan, Abby F. Fleisch, Bruce P. Lanphear, Kim M. Cecil, Kimberly Yolton, Aimin Chen, Jessie P. Buckley, and Joseph M. Braun

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Palliative and end-of-life care in Asian and White patients with metastatic lung cancer, Xiao Hu, John W. Melson, Stacey S. Pan, Yana V. Salei, Lori Pai, Susan K. Parsons, and Yu Cao

Arsenic exposure is associated with elevated sweat chloride concentration and airflow obstruction among adults in Bangladesh: A cross-sectional study, Mi-Sun S. Lee, Crystal M. North, Irada Choudhuri, Subrata K. Biswas, Abby F. Fleisch, Afifah Farooque, Diane Bao, Sakila Afroz, Sadia Mow, Nazmul Husain, Fuadul Islam, Md Golam Mostofa, Partha Pratim Biswas, and David S. Ludwig

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Arsenic exposure is associated with elevated sweat chloride concentration and airflow obstruction among adults in Bangladesh: A cross-sectional study, Mi-Sun S. Lee, Crystal M. North, Irada Choudhuri, Subrata K. Biswas, Abby F. Fleisch, Afifah Farooque, Diane Bao, Sakila Afroz, Sadia Mow, Nazmul Husain, Fuadul Islam, Md Golam Mostofa, Partha Pratim Biswas, and David S. Ludwig

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Periprosthetic Joint Infection Centers of Excellence: Moonshot or Misstep? A Survey of the American Association of Hip and Knee Surgeons Members, Meghan Whitmarsh-Brown, Catherine M. Call, Joshua A. Kerr, Carl L. Herndon, Christopher F. Deans, Ameer Elbuluk, Ramakanth Yakkanti, and Adam Rana

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A Human Centered Approach: Solving Unmet Care Needs at MaineHealth, Carla Muniz

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Analysis of Novice and Expert Rater Reliability for a Neonatal Resuscitation Program® Adherence Assessment Tool, Sophia Martens, Misty Melendi, Anya Cutler, Sierra Soghikian, Leah Marie Seften, Tara Palnitkar, Allison Zanno, and Leah Mallory

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An Opt Out Tobacco Cessation Referral Process for a Cancer Care Network, Amy Litterini, David Spaulding, Tia Robbins, Brett Cropp, and Lauren Couture

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A Quality Improvement Project to Reduce Variation in Pediatric Asthma Care Using the Hospital Asthma Severity Scoring (HASS) Tool, Sean Patterson, Leah-Marie Seften, Rachel Williams, Noah Diminick, Anne Coates, and Laura Amar-Dolan

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Characterization of Contributors to Pleural Fluid Viscosity, YuJai Lin, Megan Rushmeyer, Christopher G. Roy, Shannon Donovan, Rachel Cutting, Matthew Buttarazzi, Charlotte Crist, Ted Sears, and J B. Zuckerman

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Clinician Comfort, Attitudes, and Practices with Provision of Harm Reduction Supplies to Patients Who Use Drugs, Amanda Cahn, Melissa Calica, Erin Mooz, Malia Haddock, Wendy Craig, Tania Strout, and Kinna Thakarar

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Community Health Workers: Putting "Community" in the MaineHealth Vision, Tim Cowan, Barbara Ginley, LeeAnna Lavoie, Jennifer Maillet, Jemma Penberthy, and Lori Travis

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Electrodermal activity (EDA) confirms that PGY-1s experience more stress and distress during simulation than residents of other PGY levels, Michael Ferguson, Anya K. Cutler, Micheline Chipman, Leah Mallory, Erika Mayer, Leah M. Seften, Michael Zubrow, and Mary Ottolini

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Evaluation of Engagement and Collaboration Among Hospitals in the Maine Rural Maternity & Obstetrics Management Strategies (RMOMS) Network, Molly Volt, Lori Travis, Caroline Zimmerman, Erica Swan, Katherine Crothers, Anna Gilbert, and Kate Allerding

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Experiences with Mental Health Screening in Primary Care, Elizabeth Bernier, Merelise Ametti, Elizabeth Mutina, Saras Yerlig, Elias Peirce, Sameena Flinner, Yaerin Wallenberger, and Kristen Woodberry

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Factors Influencing No Show Rates in Adult Urology Patients, Bruce T. Ndebanje, Ethan Griffin, Evelyn James, and Lily C. Wang

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Impact of Individual Team Members on Team Performance in a Longitudinal Neonatal Resuscitation Telesimulation Program, Allison Zanno, Anya K. Cutler, Micheline Chipman, Leah Mallory, Leah M. Seften, Tara Palnitkar, Mary Ottolini, and Misty Melendi

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Implementation and Evaluation of a Resident Pediatric Complex Care Education Series, Calivin Schaffer, Danielle Doctor, Amy Buczkowski, Bonnie Lynne Boomsma, and Logan Murray

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Implementation of MOMSim 2.0, Beth Gray, Micheline Chipman, Lauren Weller, Emily Watson, Sarah Austin, Tara Palniker, and Leah Mallory

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Improving Clinician Competence to Screen for Suicide Risk: An Organizational Change, Melissa Gattine and Kendall Dapprich

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Improving MaineHealth Behavioral Health Non-clinical Staff Knowledge and Comfort to Ask About Suicide with Question, Persuade, Refer (QPR) Training, Hannah Pelletier and Julie Perron

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Infective Endocarditis in the Overdose Crisis: Addiction Care and Healthcare Utilization, Eva J. Farkas, Victoria Molina, Brittany Mohoney, Wendy Craig, Amy McAuliffe, and Kinna Thakarar

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Iterative Simulation and Healthcare Failure Modes and Effects Analysis Improves Child Abduction Response Systems Over Four Years of Testing in a Children's Hospital, Dani Bruno, Marissa Perry, Madison (Max) Doane, Jamie Fey, Micheline Chipman, Brian Richardson, and Leah Mallory

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Laying the Groundwork: Implementing the 2021 AAP Well Appearing Febrile Infant Clinical Practice Guideline Across a Rural Health System, E Freeman, L Mallory, LM Seften, T Palnitkar, A Cutler, J Gregory, and M Jackson

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Mental Health Conditions Among Patients with a Disorder of the Gut-Brain Interaction, Ambia Ahmed, Nicole Smith, Anya Cutler, MariaElena Terzis, Laura J. Faherty, and Julia Fritz

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MOMSim-A Simulation-Based Outreach Program to Maintain Team Readiness for Obstetrical Emergencies Across a Rural Health System, Lauren Weller, Micheline Chipman, Beth Gray, Becky Hunt, Emily Watson, Sarah Austin, Anya Cutler, Jeff Holmes, and Leah Mallory

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Overcoming Specialty Care Connection Barriers: The eConsult Effect, Genevieve Whiting, Noah Hoffman, Anya K. Cutler, Leah M. Seften, and Laura J. Faherty

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Parent Perspectives on Primary/Specialty Co-management of Pediatric Asthma, James Bohnhoff, Mike Kohut, Dana Schwartz, Darby Glenn, Anya Cutler, and Elizabeth A. Jacobs

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Pediatric Asthma Subspecialty Referral Practices in Rural Maine, Paras Patnaik, John DiPalazzo, and James Bohnhoff

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Pharmacist-Led Statin Initiation in Adults with Diabetes at an Adult Internal Medicine Clinic, Kevin Le, Michael Takach, Linh Gagnon, and Dylan Atchley

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Physical Activity Programming to Improve QoL in Pediatric IBD Patients, Anna Briley, George Russell, Anya K. Cutler, Anna Furr, Julia Fritz, Kevin Sztam, Birgitta Polson, Rebecca Edwards, and Noah Hoffman

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Physical Activity Programming to Improve QoL in Pediatric IBD Patients, George Russell, Anya K. Cutler, Anna Furr, Julia Fritz, Kevin Sztam, Birgitta Polson, Rebecca Edwards, and Noah Hoffman

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Pilot Study of Serial Telemedicine Assessments to Safely Exclude Neonates from Therapeutic Hypothermia Treatment, Alexa Craig and Anya K. Cutler

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Rigid Sternal Fixation Alone Does Not Result in a Reduction in Postoperative Opiod Administration Following Cardiac Surgery, Jane Branch, Chinedu Okoli, Kyla Wigant, Jaime Rabb, Robert S. Kramer, Anne Hicks, and Ansar Hassan

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Shortage as a Catalyst for High-Value Care: Evaluation of a Bloof Culture Stewardship Intervention Driven by Supply Chain Disruption, Lesley B. Gordon, Camille Ezran, Elizabeth Herrle, Christina Yen, Nicholas J. Mercuro, and Daniel J. Diekema

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Testing Paths of Travel for Pediatric Patients Using Healthcare Failure Mode and Effects Analysis (HFMEA), Micheline Chipman, Dani Bruno, Leah Mallory, Marissa Perry, Sophie Martens, and Lauren Weller

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Test-Retest Agreement and Reliability of Psychosis and Mental Health Screens for Maine Adolescents and Young Adults in Primary Care, Erika Mayer, Eb Bernier, Merelise Ametti, Julia Plumb, Adriana Lovric, Yaerin Wallenberger, and Kristen Woodberry

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Work Hard, Play Hard: How Game-Based Learning Impacts Learner's Engagement and Satisfaction in Intern Academic Half-Day, Katelyn Chadwick, Lesley Gordon, Monica Thim, and Nicole Hudak

Addressing Inpatient Hyponatremia Through Targeted Automatic E-consults: A Pilot Randomized Trial, Timothy J. Judson, Lowell Lo, John E. Demko, Michelle Mourad, Kathleen D. Liu, Robert M. Wachter, Isaac Lopez, and Sri Lekha Tummalapalli

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Addressing Inpatient Hyponatremia Through Targeted Automatic E-consults: A Pilot Randomized Trial, Timothy J. Judson, Lowell Lo, John E. Demko, Michelle Mourad, Kathleen D. Liu, Robert M. Wachter, Isaac Lopez, and Sri Lekha Tummalapalli

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A preliminary ex vivo diffusion tensor imaging study of distinct aortic morphologies, B Tornifoglio, S T. Robinson, R E. Levey, A J. Stone, S Campisi, C Kerskens, G P. Duffy, S Avril, and C Lally

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Atenolol, alone or in combination with PTH, has a modest effect on bone in female C57BL/6J mice., Rebecca L Fontaine, Daniel J Brooks, Deborah Barlow, Ryan J Neilson, Christine W Lary, Karen L Houseknecht, and Katherine J Motyl

Complementary effects of postoperative delirium and frailty on 30-day outcomes in spine surgery, Nithin K. Gupta, Stefan T. Prvulovic, Sina Zoghi, Hikmat R. Chmait, Michael M. Covell, and Cameron J. Sabet

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DERM-SUCCESS FDA Pivotal Study: A Multi-Reader Multi-Case Evaluation of Primary Care Physicians' Skin Cancer Detection Using AI-Enabled Elastic Scattering Spectroscopy, Laura K. Ferris, Erik Jaklitsch, Elizabeth V. Seiverling, Thomas Agresta, and Peggy Cyr

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Does Cohort Selection Affect Machine Learning from Clinical Data?, Atefehsadat Haghighathoseini, Janusz Wojtusiak, Hua Min, Timothy Leslie, and Cara Frankenfeld

Establishment of an Accurate and Precise Alternative Intraoperative Technique for Determination of Femoral Version, Benjamin Yao, Don Li, Jonathan Cui, Kira L. Smith, Vineet Tyagi, and Joseph B. Kahan

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Ethical considerations in shoulder arthroplasty in patients who are obese, Andrew D. Lachance, Roman Steika, Frank Chessa, Jeffrey Lutton, and Joseph Y. Choi

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Integration of Interprofessional Education Into Routine Resident Practice: 2 Cases of Successful Implementation, Catherine C. Skae, Victoria Gorski, Anna Flattau, Manaslu Gurung, Kalli Varaklis, and Sarah Hallen

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Lyme Disease, Robert P Smith

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Program Evaluation for Graduate Medical Education: Practical Approaches From the Reimagining Residency Evaluation Community of Practice, Judee Richardson, Lalena M. Yarris, Patricia A. Carney, Erin Goss, Melissa I. Zelaya, Helen K. Morgan, Fei Chen, Julie A. Schumacher, Paul O'Rourke, Colleen Gillespie, Britta M. Thompson, and Mary Ellen Goldhamer

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Seven Tips for Successfully Operationalizing GME Innovations at the System Level: The iPACE Experience, Kalli Varaklis and Sarah Hallen

The Power of Words in Research Reading and Writing, Barbara J. Patterson and Karen H. Morin

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Thermoneutral housing has limited effects on social isolation-induced bone loss in male C57BL/6J mice., Rebecca V Mountain, Rebecca L Peters, Audrie L Langlais, Julia Patrizia Stohn, Christine W Lary, and Katherine J Motyl

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Towards a consensus atlas of human and mouse adipose tissue at single-cell resolution., Anne Loft, Margo P Emont, Ada Weinstock, Adeline Divoux, Adhideb Ghosh, Allon Wagner, Matthew D Lynes, Rinki Murphy, Saeed Pirouzpanah, Silvia Corvera, Su'an Tang, Swapan K Das, Søren F Schmidt, Tao Zhang, Theodore M Nelson, Timothy E O'Sullivan, Vissarion Efthymiou, Wenjing Wang, Yihan Tong, Yu-Hua Tseng, Susanne Mandrup, and Evan D Rosen

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Visuomotor Integration Assessment Using Immersive Virtual Reality for Children With Cerebral Palsy: A Pilot Study, Minxin Cheng, Alexa Craig, and Danielle E. Levac

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Costs of Academic Engagement in Organized Neurosurgery in the United States., Michael M Covell, Stefan T Prvulovic, Immaculate Christie, Joanna M Roy, Javed Iqbal, Aryan Gajjar, Bhavya Pahwa, Charles Bowers, Cameron J Sabet, Marc D Moisi, Johnny Delashaw, Meic Schmidt, and Christian A Bowers

A Staphylococcus aureus Virulence Inhibitor Identified by SaeRS Refactoring and Screening in Bacillus subtilis, Felix Ekness, Eric A. Wold, Catherine S. Leasure, Elena Musteata, Andrew J. Monteith, and Clare Laut

A Staphylococcus aureus Virulence Inhibitor Identified by SaeRS Refactoring and Screening in Bacillus subtilis, Felix Ekness, Eric A. Wold, Catherine S. Leasure, Elena Musteata, Andrew J. Monteith, and Clare Laut

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The Impact of Glucagon-Like Peptide-1 Receptor Agonists on Pharmacokinetics and Toxicokinetics: Is a New Diagnostic and Therapeutic Framework Needed?, James D. Whitledge, Joseph Kennedy, C James Watson, Carin Malley, Karen Simone, and Mark Neavyn

Mitochondrial Responses to Conventional and Ultra-high Dose Rate (FLASH) Radiation, Emily G. Caggiano, Alan Lopez Hernandez, Trey Waldrop, Kevin Liu, and Henry Gatica-Gutierrez

Coaching Learners During Medical School Training: Faculty Reflections on the Coaching Experience, Maria A. Blanco, Lauren Boehm, and Victoria Hayes

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Establishment of an Accurate and Precise Alternative Intraoperative Technique for Determination of Femoral Version, Benjamin Yao, Don Li, Jonathan Cui, Kira L. Smith, Vineet Tyagi, and Joseph B. Kahan

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Online and in Crisis: When Social Media Impacts Mental Health, Erin L. Belfort and Paul E. Weigle

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Phantom Limb Pain Assessment Tools: A Literature Review Exploring Strengths and Limitations, Alexandra N. Jenson, Benjamin Branch, Janelle M. Richard, and Aurora Quaye