Incorporated in 1868, MMC is the state’s largest medical center, licensed for 700 beds and employing more than 9,600 people. MaineHealth Maine Medical Center’s unique role as both a community hospital and a referral center requires an unparalleled depth and breadth of services, including the state’s only allopathic medical school program, through a partnership with Tufts University School of Medicine, and a world-class biomedical research center, the MaineHealth Institute for Research.

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Submissions from 2025

Fewer Pills for Fewer Problems: Strategies for Reducing Postoperative Opioid Prescribing Following Total Joint Arthroplasty., Catherine M Call, Kamli N W Faour, Diane Jeselskis, Adam J Rana, and Mary Noyes

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Long COVID treatment trials: still more questions than answers?, Carolyn T Bramante and Clifford J. Rosen

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Midazolam in the treatment of catatonia: A case series, Nicolette Centanni, Annya Tisher, Matthew Caron, Terry Mooers, and Stephanie Nichols

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Safe Patient Care in CKD: Core Curriculum 2025, Prasheen Shah, Hassan Mahmoud, Grant Oakley, and Mark G. Parker

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Semaglutide for Type I Diabetes - A New Twist on an Old Story., Clifford J. Rosen

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Stage at Diagnosis for Common Cancers according to Rurality, Area Deprivation, and Insurance, 2017 to 2021., Kathleen M Fairfield, Kimberly Murray, Lise M Cloutier, John L Daggett, Benjamin R Felix, Christina A Kapala, Renee M Fay-Leblanc, Adriana E Nadeau, Bridget K Rauscher, Kathryn Rensenbrink, Debra A Rothenberg, and Kevin D Stein

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Toward Opioid-Free Total Hip Arthroplasty: A Retrospective Study of a Targeted Opioid Reduction Program in 229 Patients, Mary L. Noyes, Kamli N. Faour, Zoë A. Walsh, Catherine M. Call, and Johanna A. Mackenzie

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Trends in Isolated and Combined Aortic Valve Replacement for Severe Aortic Stenosis in Patients Younger Than 65 Years., Tanush Gupta, James T DeVries, Hsiang-Ching Huang, Cathy S Ross, David Butzel, James M Flynn, Michael N Young, Rony N Lahoud, Frank Ittleman, Ansar Hassan, and Harold L Dauerman

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A Mixed Methods Pilot Study of Neonatal Resuscitation Team Training for Rural Providers Using HoloBaby, a Mixed Reality Prototype Simulator, Michael Ferguson, Micheline Chipman, Anya K. Cutler, Leah Mallory, Misty Melendi, Leah M. Seften, Allison Zanno, Michael Zubrow, and Mary Ottolini

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Variable Toxicity by β-Blocker Class in Intentional Overdoses Reported To U.S. Poison Centers, C James Watson, Michael C. Monuteaux, Katherine B. Tang, and Michele M. Burns

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Comparing Claims Data to Stroke and Bleeding in the NCDR Left Atrial Appendage Occlusion Registry, Kamil F. Faridi, James V. Freeman, Yongfei Wang, Lucy Pereira, Sarah Zimmerman, and Angela Higgins

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Weekly Insulins and Therapeutic Burden in Type 2 Diabetes., Julie R Ingelfinger and Clifford J Rosen

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Patient, Hospital, and Outcome Factors Associated With Attaining Substantial Clinical Benefit Following Primary Total Hip Arthroplasty., Catherine M. Call, Aliyah A Olaniyan, Zoë A Walsh, George Babikian, Adam Rana, and Brian J. McGrory

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Neurodevelopmental Outcomes in Early Adolescence: The Pediatric Heart Network Single Ventricle Reconstruction Trial, Thomas A. Miller, Binu Sharma, Russell Gongwer, Felicia L. Trachtenberg, and Jane W. Newburger

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The emerging role of metabolomics analysis in genetic and genomic testing: A points to consider statement of the American College of Medical Genetics and Genomics (ACMG), Marcus J. Miller, Maria Laura Duque Lasio, Adam D. Kennedy, Rebecca McClellan, Devin Oglesbee, and Wendy E. Smith

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Efficacy and safety of a therapeutic humanized FSH-blocking antibody in obesity and Alzheimer's disease models., Anusha R Pallapati, Funda Korkmaz, Satish Rojekar, Steven Sims, Anurag Misra, Judit Gimenez-Roig, Aishwarya Gangadhar, Victoria Laurencin, Anisa Gumerova, Uliana Cheliadinova, Farhath Sultana, Darya Vasilyeva, and Clifford J Rosen

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Fewer Pills for Fewer Problems: Strategies for Reducing Postoperative Opioid Prescribing Following Total Joint Arthroplasty., Catherine M Call, Mary Noyes, Kamli N W Faour, Diane Jeselskis, and Adam J Rana

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Guidance in Tracheostomy Care for Speech-Language Pathologists: The Green Light Tool, Sara Penrod, Dory Forgit, and Lindsay Griffin

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Physician Payment Reform in Orthopaedic Surgery: Balancing Cost, Quality, and Access, Zachary C. Lum, R Michael Meneghini, James I. Huddleston, and Adam Rana

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Urgent/emergent carotid revascularization is associated with an increase in stroke and mortality, Elisa Caron, Jeremy D. Darling, Isa F. Van Galen, Camila R. Guetter, Jemin Park, and Kristina A. Giles

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Care of the Operational Canine in the Prehospital Environment - A Joint Position Statement and Resource Document of NAEMSP, NAVEMS, and VetCOT, Kate D. Zimmerman, Lee Palmer, Kelly E. Hall, Rita M. Hanel, and Kevin F. Jura

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Recommendations for Emergency Robotic Thoracic Conversions and Intraoperative Resuscitation: A Modified Delphi Consensus Study, Hayley Reddington, Lana Schumacher, Ammara A. Watkins, Brian Mitzman, Brianna Wachter, and Syed Quadri

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Prioritization of novel agents for further investigation in pediatric non-rhabdomyosarcoma soft tissue sarcomas: A report from the Children's Oncology Group, Jacquelyn N. Crane, David P. Douglass, Sapna Oberoi, Natalie B. Collins, and Ajay Gupta

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Management of human babesiosis - approaches and perspectives, Edouard Vannier, Klaus-Peter Hunfeld, Robert P. Smith, and Peter J. Krause

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Non-insulin therapies in management of type 1 diabetes, Zeb I. Saeed, Jayachidambaram Ambalavanan, Melanie Natasha Rayan, Palak Patadia, and Viral N. Shah

Brivaracetam effectiveness and patient-reported outcomes in clinical practice: Data from a 12-month prospective, observational study in the United States, Hina Dave, Michael R. Sperling, Hamada Hamid Altalib, Heidi Henninger, and Roger J. Porter

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Embracing Compassion for People Facing Lung Cancer-the American Cancer Society National Lung Cancer Roundtable, Jamie L. Studts, Lisa Carter-Bawa, Jill Feldman, Joan H. Schiller, and Elizabeth Scharnetzki

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Building a collaborative ecosystem across the IDeA-CTR networks in response to a public health emergency., A Jerrod Anzalone, Sharon Patrick, Amber Abel, Brad Price, Elizabeth Reisher, Kent Ripplinger, Mary Emmett, Ronald Horswell, San Chu, William B Hillegass, Francisco S Sy, Brian Melancon, H Timothy Bunnell, Susan L. Santangelo, and Clifford J. Rosen

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Commentary on Anne and her Nurse, Sam Woodworth and Katie Florescu

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Dietary effects on cardiac lipid composition, mitochondrial respiration, stress proteins and thermal tolerance in the American lobster (Homarus americanus), Melissa C. Butler, Yulica Santos-Ortega, Calvin P. Vary, Anyonya R. Guntur, and Ilka M. Pinz

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FGF21 promotes longevity in diet-induced obesity through metabolic benefits independent of growth suppression, Christy M. Gliniak, Ruth Gordillo, Yun-Hee Youm, Qian Lin, Clair Crewe, and Clifford J. Rosen

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Hoe Curious Should We Be?, Sam Woodworth MD

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Insight Into the Orientation Needs for a Neonatal Intensive Care Unit, From the Preceptor’s Perspective, Angela Cyr and Megan Flynn

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Reduction of neuronal activity mediated by blood-vessel regression in the adult brain., Xiaofei Gao, Xing-Jun Chen, Meng Ye, Jun-Liszt Li, Nannan Lu, Di Yao, Bo Ci, Fei Chen, Lijun Zheng, Yuanlei Yue, Tingbo Li, Jiafu Lin, Volkhard Lindner, Robert M Bachoo, and Woo-Ping Ge

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Safety of Intermittent Parenteral Midazolam Injection in Hospitalized Patients Admitted to Non-Intensive Care Nursing Units: A Retrospective Matched-Cohort Study, Melanie Mills, Haley Torr, Nicolette Centanni, Richard R. Riker, and David Gagnon

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Take the Vitals of Council Health! Re-Empowering Shared Governance, Justin Peterson, Dave Smith, and Kristiina Hyrkas

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Who is Completing Patient-Reported Outcome Measures following Total Hip Arthroplasty? An Investigation of Completion Characteristics to Inform the Age of Mandatory Reporting Rates., Catherine M. Call, Zoë A Walsh, Aliyah A Olaniyan, George Babikian, Brian J. McGrory, and Adam Rana

Watching five colours become six, Sam Woodworth and Christopher Smith

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Watching five colours become six, Sam Woodworth and Christopher Smith

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Modified Versions of Natural Frozen Embryo Transfers Do Not Impact Live Births, Courtney Hargreaves, Wendy Craig, Denny Sakkas, Thomas L. Toth, and Denis Vaughan

Modified Versions of Natural Frozen Embryo Transfers Do Not Impact Live Births, Courtney Hargreaves, Wendy Craig, Denny Sakkas, Thomas L. Toth, and Denis Vaughan

Pneumomastia: A Rare but Benign Mammographic Finding, Krucial Styslinger and Christina Cinelli

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Mobile Phone Auscultation Accurately Diagnoses Chronic Obstructive Pulmonary Disease Using Nonlinear Respiratory Biofluid Dynamics, Caroline Emily Gosser, Luther Daniel, Martin Huecker, Rodrigo Cavallazzi, Hiram Rivas, Jarred Jeremy Thomas, and Ryan Close

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Altered metabolomics and inflammatory transcriptomics in human bone marrow adipocytes after acute high calorie diet and acute fasting, Samantha N. Costa, Gisela Pachón-Peña, Julie Dragon, Scott Tighe, and Calvin Vary

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Evaluating community engagement efforts in a clinical and translational research initiative., Kelly Finck Waters, Brenda Joly, Carolyn E Gray, Jan K Carney, and Kathleen M Fairfield

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Embracing Compassion for People Facing Lung Cancer-the American Cancer Society National Lung Cancer Roundtable, Jamie L. Studts, Lisa Carter-Bawa, Jill Feldman, Joan H. Schiller, and Elizabeth Scharnetzki

Embracing Compassion for People Facing Lung Cancer-the American Cancer Society National Lung Cancer Roundtable, Jamie L. Studts, Lisa Carter-Bawa, Jill Feldman, Joan H. Schiller, and Elizabeth Scharnetzki

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Lessons learned: enhancing rural risk communication for future health crises through the PHERCC framework., Abimbola Leslie, Elizabeth K Woods, Eline M van den Broek-Altenburg, Gary S Stein, and Jan K Carney

A Case of a Portuguese Man-O-War Envenomation in Southern Rhode Island, Sean Bilodeau, Teresa Howard, and Alexis S. Kearney

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A Case of a Portuguese Man-O-War Envenomation in Southern Rhode Island, Sean Bilodeau, Teresa Howard, and Alexis S. Kearney

A Case of a Portuguese Man-O-War Envenomation in Southern Rhode Island, Sean Bilodeau, Teresa Howard, and Alexis S. Kearney

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Addiction Consultation and Medications for Substance Use Disorders Associated with Reduced 30-Day Readmission Rates, Michael Tozier MD

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Guanfacine for the management of the behavioral manifestations of delirium in older hospitalized adults., Kayla Garvey, Kobi Griffith, Emily Carter, Wendy Craig, David J Gagnon, Richard Riker, and Nicolette Centanni

The importance of the anterior nasal spine in predicting soft tissue movement in maxillary orthognathic surgery, Kehan Li, Wingyan Chow, Zhaokun Zhu, Liwei Huang, and Yao Liu

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The importance of the anterior nasal spine in predicting soft tissue movement in maxillary orthognathic surgery, Kehan Li, Wingyan Chow, Zhaokun Zhu, Liwei Huang, Yao Liu, and Hanghang Liu

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Adult Long Coronavirus Disease 2019: Definition, Prevalence Pathophysiology, and Clinical Manifestations., Ivette Emery and Clifford J. Rosen

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Advocating for a Neonatal Fellowship Based on the Fundamentals of Care, Angela Cyr and Megan Flynn

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Cardiac Foreign Body, Joshua Rehberg, Alexander Lange, and David C. Mackenzie

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Emphasizing the Context of Care within the Fundamentals of Care Framework: Participating in AACNs Healthy Work Environment National Collaborative, Emily Bovino MSN, CNL, CCRN

"It's hard to talk to a computer, I get it": An exploratory analysis of clinician connection-building communication practices in rural telepalliative care encounters, Elise C. Tarbi

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NOTCH Signaling Networks in Perivascular Adipose Tissue., Christian Potts, Chenhao Yang, and Lucy Liaw

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Oral Care and Documentation for Mechanically Ventilated Patients, Amy Stafford

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Phantom Limb Pain Assessment Tools: A Literature Review Exploring Strengths and Limitations, Alexandra N. Jenson, Benjamin Branch, Janelle M. Richard, and Aurora Quaye

Pneumomastia: A Rare but Benign Mammographic Finding, Krucial Styslinger and Christina Cinelli

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Reflections on Implementation of Fundamentals of Care (FoC) in Practice and Research in One Magnet Hospital Utilizing Ovid Synthesis, Rhonda Babine and Kristiina Hyrkas

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Screening for Early Emerging Mental Experiences: Feasibility of Psychosis Screening in Integrated Care Settings., Kristen A Woodberry, Elizabeth Bernier, Katherine M Elacqua, David M Weiss, Stacey M Ouellette, Jonathan Fanburg, Deborah Q Hagler, Kathleen A Herlihy, Paul L Hyman, Rebecca B Jaynes, Saras Yerlig, and Amy M Mayhew

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Short-term dietary methionine restriction with high fat diet counteracts metabolic dysfunction in male mice., Marissa I McGilvrey, Bethany Fortier, Diana Cooke, Maryam A Mahdi, Benjamin Tero, Christian M Potts, Abigail Kaija, Larisa Ryzhova, Carolina Cora, Adam Richardson, Douglas Guzior, Ilka Pinz, Calvin Vary, Robert A Koza, Gene Ables, and Lucy Liaw

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The Anterior-Based Muscle-Sparing Approach for Conversion Total Hip Arthroplasty is Safe and Effective., Catherine M Call, Johanna Mackenzie, Zoë A Walsh, Bailey Shevenell, George Babikian, Brian J. McGrory, and Adam Rana

The implementation of an electronic symptom management system to monitor postoperative pain in thoracic surgery patients: A multicenter evaluation, Jorind Beqari, Jacob Hurd, Angela C. Tramontano, Christine Cronin, Alexandra Potter, and Jessica Bian

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The implementation of an electronic symptom management system to monitor postoperative pain in thoracic surgery patients: A multicenter evaluation, Jorind Beqari, Jacob Hurd, Angela C. Tramontano, Christine Cronin, Alexandra Potter, and Jessica Bian

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The Optimizing Whiteboard Lectures (OWL) Checklist: A Novel "Chalk Talk" Assessment Tool., Ryan E Nelson, Jason A Freed, Tianyu Sissi Chen, Monica Thim DO, Sarah Olofsson, and Daniel N Ricotta

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Using the Fundamentals of Care Framework to Design an Online Skills Training Program for Spiritual Care Providers, Heather Weidemann

Impact of Physiological Stress and Reserve on the Cost of Care: Operative Stress Score and Frailty, Timothy L. Fitzgerald, Laura Nicolais, Aurora Quaye, Janelle M. Richard, and Peter Hubbs

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Impact of Physiological Stress and Reserve on the Cost of Care: Operative Stress Score and Frailty, Timothy L. Fitzgerald, Laura Nicolais, Aurora Quaye, Janelle M. Richard, and Peter Hubbs

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The Bronchoalveolar Proteome Changes in Obesity, William G. Tharp, Carlos A. Gartner, Yulica Santos-Ortega, Calvin P. Vary, and S Patrick Bender

The Bronchoalveolar Proteome Changes in Obesity, William G. Tharp, Carlos A. Gartner, Yulica Santos-Ortega, Calvin P. Vary, and S Patrick Bender

The Bronchoalveolar Proteome Changes in Obesity, William G. Tharp, Carlos A. Gartner, Yulica Santos-Ortega, Calvin P. Vary, and S Patrick Bender

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Efficacy of stochastic vibro-tactile stimulation for newborns at risk of neonatal opioid withdrawal syndrome, Rachana Singh, Ludovic Trinquart, Benjamin Koethe, Mario Cordova, Lawrence Rhein, Shawana Bibi, Jamie Fey, Ariana Anderson, and Jonathan M. Davis

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Ethical Management of Challenging Behaviors in Hospitalized People Who Use Drugs, Christina Yen, Kinna Thakarar, and Tim Lahey

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Perioperative management of patients taking glucagon-like peptide 1 receptor agonists: Society for Perioperative Assessment and Quality Improvement (SPAQI) multidisciplinary consensus statement, Adriana D. Oprea, Laura J. Ostapenko, BobbieJean Sweitzer, Angela Selzer, Joan M. Irizarry-Alvarado, Maria D. Hurtado Andrade, Carlos E. Mendez, Kristen D. Kelley, Erin Stewart, Claudia R. Fernandez Robles, Ryan M. Chadha, Michael Camilleri, Ruchi Mathur, and Guillermo E. Umpierrez

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Safety and efficacy of pegtibatinase enzyme replacement therapy in adults with classical homocystinuria in the COMPOSE® phase 1/2 randomized trial, Can Ficicioglu, Janet A. Thomas, Jaya Ganesh, David Kudrow, Melissa Lah, Wendy E. Smith, Jalé Güner, Sharon McDermott, Sagar A. Vaidya, Liz Wilkening, and Harvey L. Levy

Early-life and concurrent predictors of the healthy adolescent microbiome in a cohort study, Hannah E. Laue, Amy D. Willis, Fang Wang, Melinda C. MacDougall, Yingying Xu, Margaret R. Karagas, Juliette C. Madan, Abby F. Fleisch, and Bruce P. Lanphear

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Early-life and concurrent predictors of the healthy adolescent microbiome in a cohort study, Hannah E. Laue, Amy D. Willis, Fang Wang, Melinda C. MacDougall, Yingying Xu, Margaret R. Karagas, Juliette C. Madan, Abby F. Fleisch, Bruce P. Lanphear, Kim M. Cecil, Kimberly Yolton, Aimin Chen, Jessie P. Buckley, and Joseph M. Braun

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Palliative and end-of-life care in Asian and White patients with metastatic lung cancer, Xiao Hu, John W. Melson, Stacey S. Pan, Yana V. Salei, Lori Pai, Susan K. Parsons, and Yu Cao

Arsenic exposure is associated with elevated sweat chloride concentration and airflow obstruction among adults in Bangladesh: A cross-sectional study, Mi-Sun S. Lee, Crystal M. North, Irada Choudhuri, Subrata K. Biswas, Abby F. Fleisch, Afifah Farooque, Diane Bao, Sakila Afroz, Sadia Mow, Nazmul Husain, Fuadul Islam, Md Golam Mostofa, Partha Pratim Biswas, and David S. Ludwig

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Arsenic exposure is associated with elevated sweat chloride concentration and airflow obstruction among adults in Bangladesh: A cross-sectional study, Mi-Sun S. Lee, Crystal M. North, Irada Choudhuri, Subrata K. Biswas, Abby F. Fleisch, Afifah Farooque, Diane Bao, Sakila Afroz, Sadia Mow, Nazmul Husain, Fuadul Islam, Md Golam Mostofa, Partha Pratim Biswas, and David S. Ludwig

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Periprosthetic Joint Infection Centers of Excellence: Moonshot or Misstep? A Survey of the American Association of Hip and Knee Surgeons Members, Meghan Whitmarsh-Brown, Catherine M. Call, Joshua A. Kerr, Carl L. Herndon, Christopher F. Deans, Ameer Elbuluk, Ramakanth Yakkanti, and Adam Rana

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A Human Centered Approach: Solving Unmet Care Needs at MaineHealth, Carla Muniz

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Analysis of Novice and Expert Rater Reliability for a Neonatal Resuscitation Program® Adherence Assessment Tool, Sophia Martens, Misty Melendi, Anya Cutler, Sierra Soghikian, Leah Marie Seften, Tara Palnitkar, Allison Zanno, and Leah Mallory

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An Opt Out Tobacco Cessation Referral Process for a Cancer Care Network, Amy Litterini, David Spaulding, Tia Robbins, Brett Cropp, and Lauren Couture

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A Quality Improvement Project to Reduce Variation in Pediatric Asthma Care Using the Hospital Asthma Severity Scoring (HASS) Tool, Sean Patterson, Leah-Marie Seften, Rachel Williams, Noah Diminick, Anne Coates, and Laura Amar-Dolan

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Challenges and solutions of consenting and interviewing Spanish Family members/Friends in a study utilizing text messaging for communication during ambulatory surgery, Sonja Orff, Jenny Gilmore, and Kristiina Hyrkas

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Characterization of Contributors to Pleural Fluid Viscosity, YuJai Lin, Megan Rushmeyer, Christopher G. Roy, Shannon Donovan, Rachel Cutting, Matthew Buttarazzi, Charlotte Crist, Ted Sears, and J B. Zuckerman

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Clinician Comfort, Attitudes, and Practices with Provision of Harm Reduction Supplies to Patients Who Use Drugs, Amanda Cahn, Melissa Calica, Erin Mooz, Malia Haddock, Wendy Craig, Tania Strout, and Kinna Thakarar

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Community Health Workers: Putting "Community" in the MaineHealth Vision, Tim Cowan, Barbara Ginley, LeeAnna Lavoie, Jennifer Maillet, Jemma Penberthy, and Lori Travis

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Electrodermal activity (EDA) confirms that PGY-1s experience more stress and distress during simulation than residents of other PGY levels, Michael Ferguson, Anya K. Cutler, Micheline Chipman, Leah Mallory, Erika Mayer, Leah M. Seften, Michael Zubrow, and Mary Ottolini

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Evaluation of Engagement and Collaboration Among Hospitals in the Maine Rural Maternity & Obstetrics Management Strategies (RMOMS) Network, Molly Volt, Lori Travis, Caroline Zimmerman, Erica Swan, Katherine Crothers, Anna Gilbert, and Kate Allerding

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Experiences with Mental Health Screening in Primary Care, Elizabeth Bernier, Merelise Ametti, Elizabeth Mutina, Saras Yerlig, Elias Peirce, Sameena Flinner, Yaerin Wallenberger, and Kristen Woodberry

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Factors Influencing No Show Rates in Adult Urology Patients, Bruce T. Ndebanje, Ethan Griffin, Evelyn James, and Lily C. Wang

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Impact of Individual Team Members on Team Performance in a Longitudinal Neonatal Resuscitation Telesimulation Program, Allison Zanno, Anya K. Cutler, Micheline Chipman, Leah Mallory, Leah M. Seften, Tara Palnitkar, Mary Ottolini, and Misty Melendi