Incorporated in 1868, MMC is the state’s largest medical center, licensed for 700 beds and employing more than 9,600 people. MaineHealth Maine Medical Center’s unique role as both a community hospital and a referral center requires an unparalleled depth and breadth of services, including the state’s only allopathic medical school program, through a partnership with Tufts University School of Medicine, and a world-class biomedical research center, the MaineHealth Institute for Research.

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Submissions from 2025

"It's hard to talk to a computer, I get it": An exploratory analysis of clinician connection-building communication practices in rural telepalliative care encounters, Elise C. Tarbi

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A Hot Topic: Standardization of Fire Safety Training in Perioperative Areas, Megan Benner MSN-Ed, RN, CPAN, NPD-BC

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Associations of maternal per- and polyfluoroalkyl substance plasma concentrations during pregnancy with offspring polycystic ovary syndrome and related characteristics in project viva, Zifan Wang, Abby Fleisch, Sheryl L. Rifas-Shiman, Antonia M. Calafat, Tamarra James-Todd, and Brent A. Coull

The Bibliometric Evolution of Neurosurgery Publications From 1977 to 2023, Michael M. Covell

Conversion from Minimally Invasive Surgical Approaches to Open Surgery Among Patients with Endometrial Cancer in the SGO Clinical Outcomes Registry, Abdelrahman Yousif

Correction: Spatial and temporal distribution of Ixodes scapularis and tick-borne pathogens across the northeastern United States, Lucas E. Price

Financial impacts of the COVID-19 pandemic on immigrant communities in Portland Maine: a qualitative study, Eilish W. Carpenter

Noncoding variants and sulcal patterns in congenital heart disease: Machine learning to predict functional impact, Enrique Mondragon-Estrada

Telemedicine consultations in community hospitals improve neonatal encephalopathy assessment, Anya Cutler

Perfluoroalkyl substances and preterm birth, Anne M. Mullin

Trends in Orthopaedic Surgeon Compensation: A Comparative Analysis over Twenty Years, Daniel E. Pereira

Prior Authorization in Joint Arthroplasty Surgery: Navigating Challenges, Ramakanth Yakkanti

A Quality Improvement Initiative to Optimize Follow-Up in the New England Area for Pediatric Patients With Cardiovascular Implantable Electronic Devices, Zoe Schefter

Canagliflozin-induced adaptive metabolism in bone, Sher Bahadur Poudel

Morphometric vertebral fractures at hospitalization associate with Long COVID occurrence, Luigi di Filippo

A "Most Interesting Journey" to America for the International Society of Surgery in 1914, David E. Clark

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Vitamin A deficiency and male-specific effects on heart function in mice, Ian M. Gans, Elena Chepurko, Vadim Chepurko, Grazina A. Mangoba, Mary Ann Asson-Batres, and Calvin P. Vary

Aging alters the effect of adiponectin receptor signaling on bone marrow-derived mesenchymal stem cells, Hanghang Liu

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Buprenorphine in the Intensive Care Unit: Commentary on the Unanswered Questions, David J. Gagnon, Melody J. Glenn, Aurora A. Quaye, and Brian L. Erstad

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Female patients have fewer limb amputations compared to male patients in the BEST-CLI trial, Katharine L. McGinigle, Gheorghe Doros, Olamide Alabi, Benjamin S. Brooke, Ageliki Vouyouka, Jade Hiramoto, and Kristina Giles

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Innovative Technology to Improve Simulation Access for Rural Clinicians, Allison Zanno, Jeffrey Holmes, Misty Melendi, and Michael Ferguson

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Preparing Residents for Rural Practice and Advocacy: The Experiences of Three Residency Training Programs in the Northeast United States (2009-2023), Brian Youth, Carol Lynn O'Dea, and Jill Rinehart

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Rural Pediatric Health Care: A Century of Challenges and a Millennium of Opportunities, Mary Ottolini

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Symptom management in isocitrate dehydrogenase mutant glioma, Tobias Walbert, Edward K. Avila, Florien W. Boele, Caroline Hertler, Christine Lu-Emerson, and Pim B. van der Meer

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The Osmolal Gap: A Valuable Test for Identifying Toxic Alcohol-Induced Anion Gap Metabolic Acidosis, James D. Whitledge, Emily Guy, and Christopher James Watson

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Tools for Improving Access to Subspecialty Care Among Rural Children, Genevieve Whiting and James C. Bohnhoff

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Treatment of Pediatric Obesity in Rural Settings: Identifying and Overcoming Barriers to Care, Rushika Conroy, Carrie Gordon, and Valerie M. O'Hara

Comparison of Lysis and Amplification Methodologies for Optimal 16S rRNA Gene Profiling for Human and Mouse Microbiome Studies, Farzaneh Rastegari

Data Collection Variability Across Neonatal Hypoxic-Ischemic Encephalopathy Registries, Eric S. Peeples

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Inhibition of acyl-CoA synthetase long-chain isozymes decreases multiple myeloma cell proliferation and causes mitochondrial dysfunction, Connor S. Murphy, Heather Fairfield, Victoria E. DeMambro, Samaa Fadel, Carlos A. Gartner, and Michelle Karam

Time Until Operation for Elective Endovascular Aortic Aneurysm Repair in Canadian Vascular Centers Using the Canadian Vascular Quality Initiative Registry, Nadia O. Trabelsi

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Cross-titration from risperidone to clozapine utilizing clozapine serum concentrations: A case report, Nicolette Centanni, Kayla Garvey, Elizabeth Mullany, and Stephanie Nichols

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Rural School-Based Health Centers: Meeting Children Where They Are to Improve Asthma Outcomes, James C. Bohnhoff, Abby Fleisch, and Jill S. Halterman

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Noise audit of device selection for peripheral vascular interventions in the Vascular Quality Initiative, William K. Robinson, Peter W. Callas, Jens Eldrup-Jorgensen, and Daniel J. Bertges

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Performance of transesophageal echocardiography probe at temperature monitoring during simulated hypothermia and rewarming, Madeline Larochelle, Margarita Popova, David Mackenzie, Andrew Fried, Peter Croft, and Joshua Rehberg

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Trends in Osteoporosis Drug Therapy Receipt Among Commercial and Medicare Advantage Enrollees in the United States, 2011-2022, Alexander O. Everhart, Juan P. Brito, Bart L. Clarke, Jeph Herrin, Pinar Karaca-Mandic, Kurt A. Kennel, and Clifford J. Rosen

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Bone Marrow Adipocytes as Novel Regulators of Metabolic Homeostasis: Clinical Consequences of Bone Marrow Adiposity, Hanghang Liu, Linyi Liu, and Clifford J. Rosen

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AI Diabetic Retinopathy Screening in a Primary Care Setting in Rural Maine, Rachel Heuer, Emma DayBranch, Anastasia Tsomides, Jessica F. DiBiase, Neil Korsen, and Brian Nolan

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How is Telehealth Used to Increase Access to Specialty Palliative Care? A Systematic Review, Rebecca N. Hutchinson, Eric J. Chiu, Shane C. Belin, Michele Klein-Fedyshin, Carolyn R. Impagliazzo, and Lucia Costanza

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Associations between COVID-19 therapies and outcomes in rural and urban America: A multisite, temporal analysis from the Alpha to Omicron SARS-CoV-2 variants, A Jerrod Anzalone, William H. Beasley, Kimberly Murray, William B. Hillegass, Makayla Schissel, Michael T. Vest, Scott A. Chapman, Ronald Horswell, Lucio Miele, H Timothy Bunnell, Susan L. Santangelo, and Clifford J. Rosen

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C-Reactive Protein Changes in Adult and Pediatric People With Cystic Fibrosis During Treatment of Pulmonary Exacerbations, Jonathan B. Zuckerman, Alexandra C. Hinton, Thomas Lahiri, Charlotte C. Teneback, Shijing Jia, and Joel Mermis

Efficacy and safety of LAU-7b in a Phase 2 trial in adults with cystic fibrosis, Michael W. Konstan

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Is Pathogen Molecular Testing Reshaping Outpatient Antibiotic Prescribing?, Barbara D. Alexander, William D. Irish, Adriana E. Rosato, Barry I. Eisenstein, Maren S. Fragala, and Steven E. Goldberg

Long-term Outcomes of Persistent Postoperative Opioid Use: A Retrospective Cohort Study, Jeffrey J. Aalberg, Marc Kimball, Timothy R. McIntire, and Geoffrey M. McCullen

My Bad, You Got This: witnessing, therapist attitude and the synergy between psychedelics and inner healing intelligence in the treatment of trauma, Lawrence Fischman

The rise of endovascular repair for abdominal, thoracoabdominal, and thoracic aortic aneurysms, Patrick D. Conroy, Vinamr Rastogi, Sai Divya Yadavalli, Yoel Solomon, Anne-Sophie Romijn, Kirsten Dansey, Hence J. Verhagen, Kristina Giles, and Joseph V. Lombardi

Submissions from 2024

Net Promoter Score as a Reflection of Patients' Opinions About Telemedical Visits: A Mixed Methods Analysis, Mike Kohut, Tracy Jalbuena, Rachel Alfiero, John DiPalazzo, Eric Anderson, and Jasmine Bishop

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Physicians preference for carotid revascularization impacts postoperative stroke and death outcomes, Hanaa D. Aridi, Geneva Frank, Ashley R. Gutwein, Mackenzie Madison, Marc L. Schermerhorn, Vikram S. Kashyap, and Jens Eldrup-Jorgensen

Advancing Delirium Assessment in Neurocritically Ill Adults, John W. Devlin and Richard R. Riker

Medicaid‑Insured Children with Medical Complexity in a Rural State, James Bohnhoff, Chelsea Bodnar, Jon Graham, Jonathon Knudson, Erika Fox, Cindy Leary, Lauren Cater, and Curtis Noonan

The impact of climate change induced natural disasters on healthcare: Rethinking intravenous fluids, Elizabeth A. Cerceo, Katherine T. Liu, Evans K. Brown, and Catherine Chen

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Negative feedback between PTH1R and IGF1 through the Hedgehog pathway in mediating craniofacial bone remodeling, Yi Fan, Ping Lyu, Jiahe Wang, Yali Wei, Zucen Li, Shiwen Zhang, Takehito Ouchi, Junjun Jing, Quan Yuan, Chenchen Zhou, and Clifford J. Rosen

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Brief Report: Genital Microbiome, Inflammation, and Tenofovir Levels in Transgender Men and Cisgender Women Taking Oral PrEP, Elizabeth Hastie, Megha S. Srivatsa, Sara Gianella, Mackenzie Cottrell, Kyra Forsyth, Magali Porrachia, and Stephen Rawlings

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Evaluation of a Pregnancy Options Counseling Curriculum for Pediatric Residents, Laura Kirkpatrick, Lauren A. Bell, Theresa Borcky, Hannah Boutros-Khoury, Jayde Hooven-Davis, Jacquelin Rankine, Cynthia Robbins, Tahniat Syed, and Nicholas Szoko

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Pharmacogenetic and microRNA mechanisms of beta blocker use on bone, Christine W. Lary, Elizabeth J. Atkinson, Jennifer Spillane, Zannatun Nayema, Tyler A. Roy, Rebecca Peters, Griffin T. Scott, Hongyu Chen, Archana Nagarajan, Katherine J. Motyl, and Aaron C. Brown

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Kidney stone analysis: an EAU section of urolithiasis (EULIS) survey on current practices and perspectives worldwide, Simone J. Stoots, Bhaskar K. Somani, Otas Durutovic, Vitor Cavadas, Armin Secker, Helene Ulrik Jung, Øyvind Ulvik, Johann Ingimarsson, Tzevat Tefik, and Laurian Dragos

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Assessment of sous vide water baths in the acute rewarming of frostbitten extremities: A multicenter study, Nicholas J. Daniel, Johndavid M. Storn, Nicholas E. Weinberg, William A. Galvin, Hillary R. Irons, Aaron N. Barksdale, Megan L. Rischall, Sean M. Bilodeau, Jasmine Y. Gale, Katherine G. Willet, Amalya Wilson, Kara Keiper, and Jessica Chevalier

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Enhanced fatty acid oxidation in osteoprogenitor cells provides protection from high-fat diet induced bone dysfunction, Ananya Nandy, Ron C. Helderman, Santosh Thapa, Sun H. Peck, Alison Richards, Shobana Jayapalan, Nikita Narayani, Michael P. Czech, and Clifford J. Rosen

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Current state of neurodevelopmental and psychosocial care practices for paediatric patients with ventricular assist devices: an Advanced Cardiac Therapies Improving Outcomes Network and Cardiac Neurodevelopmental Outcome Collaborative collaborative survey, Catherine R. Dusing, Elise Turner, Lauren Smyth, Adam R. Cassidy, Melanie D. Everitt, Riki Graves, Dawn L. Ilardi, Thomas Miller, Melissa McQueen, Hannah Roberts, and Bonnie Bolin

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Rate and setting of neurodevelopmental and psychosocial encounters for children with CHD, James C. Bohnhoff, Anya Cutler, Julia Price, Katherine Ahrens, Sarah M. Gabrielson, Warren Hathaway, and Thomas A. Miller

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The pathoanatomy of medial ligamentous disruption in the dislocated and multiple ligament injured knee, Nancy Park, Jay Moran, Logan Petit, Joseph Kahan, William McLaughlin, Peter Joo, Michael Lee, Joshua Green, Kinjal Vasavada, Isabel Chalem, Peter Jokl, Michael J. Alaia, and Michael J. Medvecky

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Features of Consistent Powassan Virus Lineage II Focus in Southern Maine, United States, Lindsay Baxter, Charles Lubelczyk, Laura C. Harrington, Jake Angelico, Molly C. Meagher, Robert P. Smith, and Rebecca M. Robich

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Respiratory equality: let's stop playing favorites with COVID-19 in the healthcare setting, Catherine L. Passaretti, Werner Bischoff, Justin Chan, Daniel J. Diekema, Shira Doron, Carolee Estelle, Jesse T. Jacob, Tsun Sheng Ku, and Surbhi Leekha

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Nonopioid medications for managing opioid withdrawal in acute care settings: A scoping review, Brian L. Erstad, Aurora Quaye, Megan E. Hellwege, David Do, and Brian J. Kopp

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Phenylalanine hydroxylase deficiency diagnosis and management: A 2023 evidence-based clinical guideline of the American College of Medical Genetics and Genomics (ACMG), Wendy E. Smith, Susan A. Berry, Kaitlyn Bloom, Christine Brown, Barbara K. Burton, Olivia M. Demarest, Gabrielle P. Jenkins, Jennifer Malinowski, and Kim L. McBride

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A new method to evaluate fluoroscopic system collimator performance, Joseph R. Steiner, Courtney K. Morrison, Mayur Vaya, Nicholas Bevins, Jeremy Christophel, and Matt Vanderhoek

Associations of PFAS concentrations during pregnancy and midlife with bone health in midlife: Cross-sectional and prospective findings from Project Viva, Pi-I Debby Lin, Andres Cardenas, Lisa B. Rokoff, Sheryl L. Rifas-Shiman, Mingyu Zhang, Julianne Botelho, Antonia M. Calafat, and Diane R. Gold

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Changing behavior and promoting clinical empathy through a patient experience curriculum for health profession students, Sara W. Nelson, Carl Germann, Rachel Yudkowsky, Benjamin Pare, Lauren Wendell, Michael Blackie, Tania Strout, and Laura E. Hirshfield

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Early identification of vascular access site complications and frequent heart rate and blood pressure monitoring after cardiac catheterization: A scoping review, Janelle Beaudry Clark and Eira Hyrkas

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Outcomes following carotid revascularization in patients with prior ipsilateral carotid artery stenting in the Vascular Quality Initiative, Gabriel Jabbour, Sai Divya Yadavalli, Vinamr Rastogi, Elisa Caron, Tim J. Mandigers, Grace J. Wang, Brian W. Nolan, Mahmoud Malas, Jason T. Lee, Roger B. Davis, Lars Stangenberg, and Marc L. Schermerhorn

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Resident Physicians Can Promote Environmental Health and Climate-Informed Health Care, Jacob Rha, Camille Ezran, Katherine T. Liu, and Lesley B. Gordon

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Transgenerational epigenetic self-memory of dosage is associated with methylation and altered growth trajectories and neonatal hormones, M Elena Martinez, Aldona Karaczyn, Zhaofei Wu, Christian A. Bennett, Kassey L. Matoin, Heather M. Daigle, and Arturo Hernandez

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A contemporary review of sudden cardiac arrest and death in competitive and recreational athletes, Jonathan H. Kim, Matthew W. Martinez, J Sawalla Guseh, Sheela Krishnan, Belinda Gray, Kimberly G. Harmon, Michael Papadakis, Dermot M. Phelan, Katie Stewart, Benjamin D. Levine, and Aaron L. Baggish

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The relationship between adverse childhood experiences and disorders of the gut-brain interaction, Julia Fritz, Rachel Coffey, Jackson Bloch, Anya Cutler, Sarah Gabrielson, Stephen DiGiovanni, and Laura J. Faherty

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Mid-Childhood Plasma Concentrations of Per- and Polyfluoroalkyl Substances, Modifiable Lifestyle Factors, and Bone Mineral Density Through Late Adolescence, Lisa B. Rokoff, Sheryl L. Rifas-Shiman, Izzuddin M. Aris, Pi-I D. Lin, Clifford J. Rosen, and Abby F. Fleisch

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Strategies for implementing an electronic patient-reported outcomes-based symptom management program across six cancer centers, Michael Hassett, Samira Dias, Christine Cronin, Deborah Schrag, Nadine McCleary, Jessica Bian, and James Reich

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Calorie restriction induces mandible bone loss by regulating mitochondrial function, Linyi Liu, Phuong T. Le, Victoria E. DeMambro, Tiange Feng, Hanghang Liu, and Clifford J. Rosen

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Integrating an industrial hygienist into the infection prevention and control program, Angelique Dains, Spencer Baker, Takaaki Kobayashi, Stephanie Holley, Daniel Diekema, and Karen Brust

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Comparison of open and endovascular left subclavian artery revascularization for zone 2 thoracic endovascular aortic repair, Tim J. Mandigers, Sara Allievi, and Kristina Giles

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Editorial: Artificial intelligence and multimodal medical imaging data fusion for improving cardiovascular disease care, Saeed Amal, Douglas Sawyer, and Arda Könik

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Herpes Gladiatorum in College-Aged Wrestler, Joseph M. Minichiello, TImothy Fleming, Karen Olson, Brian Malley, and Lauren Wendell

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Individualizing care for patients with gallbladder cancer, Laura M. Nicolais and Timothy Fitzgerald

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Magnitude of obesity alone does not alter the alveolar lipidome, William G. Tharp, Carolyn R. Morris, Yulica Santos-Ortega, and Calvin Vary

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Primary Pulmonary Choriocarcinoma With Lymph Node Metastasis: A Case Report and Brief Review, Chinedu Okoli, Brianna Philbrick, and Syed Quadri

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Seven years of the transcarotid artery revascularization surveillance project, comparison to transfemoral stenting and endarterectomy, Sabrina Straus, Sai Divya Yadavalli, and Jens Eldrup-Jorgensen

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The European Discovery of American Surgery Volume 1: Land of Unlimited Possibilities, David Clark

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Platelet FcγRIIa as a Marker of Cardiovascular Risk After Myocardial Infarction, David J. Schneider, Sean R. McMahon, and Patrick Hohl

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Cellular Characteristics and Protein Signatures of Human Adipose Tissues from Donors With or Without Advanced Coronary Artery Disease, Caitlin P. Ellis, Benjamin W. Tero, Christian M. Potts, Kimberly T. Malka, Xuehui Yang, Joshua Hamilton, Calvin Vary, Andre Khalil, and Lucy Liaw

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Awake Supraglottic Airway Placement in Pediatric Patients for Airway Obstruction or Difficult Intubation: Insights From an International Airway Registry (PeDI), Mckenna Longacre, Raymond S. Park, and Jonathan Meserve

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Intravascular ultrasound in the assessment of coronary artery anomalies in young patients: a tertiary center experience, Mounica Y. Rao, Lindsay F. Eilers, and Ziyad Binsalamah

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Association of inpatient and outpatient pediatric palliative care with healthcare utilization and end-of-life outcomes in pediatric oncology, Rebecca L. Shamah and Elizabeth George

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Association between community distress and return to work after burn injury, Lauren L. Agoubi, Scha'Chia Murphy, Kara McMullen, Gretchen J. Carrougher, Stephanie A. Mason, and Damien Carter

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A qualitative study of how structural vulnerability shaped COVID-19 testing behaviors in Portland, Maine, Michael Kohut PhD, Gloria Sclar, Leslie Nicoll, Caroline Fernandes, Andrew Volkers, and Ann Tucker

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Associations of ethnicity, skin tone, and genome-wide sequencing with bone mineral density in adolescents, Catherine M. Gordon, Abby F. Fleisch, Marie-France Hivert, Lisa B. Rokoff, Sheryl L. Rifas-Shiman, Jean L. Raphael, and Emily Oken

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Effects of non-pharmaceutical interventions on COVID-19 transmission: rapid review of evidence from Italy, the United States, the United Kingdom, and China, Laura J. Faherty, Pedro Nascimento de Lima, Jing Zhi Lim, Derek Roberts, Sarah Karr, and Emily Lawson

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Prevalence and Genetic Diversity of Deer Tick Virus (Powassan Virus, Lineage II) in Ixodes scapularis Ticks in Five Habitats at a Nature Reserve in Southern Maine, United States, Rebecca M. Robich, Anne Piantadosi, Susan P. Elias, Danielle S. Cosenza, Elizabeth F. Schneider, Lindsay Baxter, Erin LaFon, Charles B. Lubelczyk, Molly Meagher, Chantal B. Vogels, and Robert P. Smith

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Brown fat ATP-citrate lyase links carbohydrate availability to thermogenesis and guards against metabolic stress, Ekaterina D. Korobkina, Camila Martinez Calejman, John A. Haley, Miranda E. Kelly, Huawei Li, Maria Gaughan, Qingbo Chen, and Matthew D. Lynes

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Higher FSH Level Is Associated With Increased Risk Of Incident Hip Fracture In Older Adults, Independent Of Sex Hormones, Eileen H. Koh, Susan K. Ewing, Sigurdur Sigurdsson, Vilmundur Gudnason, Trisha F. Hue, Eric Vittinghoff, Claes Ohlsson, Åsa Tivesten, Louise Grahnemo, Tony Yuen, Mone Zaidi, Clifford J. Rosen, Ann V. Schwartz, and Anne L. Schafer

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Comparison of two modeling approaches for the identification of predictors of complications in children with cerebral palsy following spine surgery, Rachel L. Difazio, Tania D. Strout, Judith A. Vessey, Jay G. Berry, and Daniel G. Whitney

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Evaluating the safety and efficacy of medical management in extracranial pseudoaneurysms: a comparative study, Jean Filo, Felipe Ramirez-Velandia, Donna Lawlor, Michael Young, Samuel D. Pettersson, Thomas B. Fodor, and Robert D. Ecker