Incorporated in 1868, MMC is the state’s largest medical center, licensed for 700 beds and employing more than 9,600 people. Maine Medical Center’s unique role as both a community hospital and a referral center requires an unparalleled depth and breadth of services, including the state’s only allopathic medical school program, through a partnership with Tufts University School of Medicine, and a world-class biomedical research center, the MaineHealth Institute for Research.

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Submissions from 2011

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An assessment of patient satisfaction with nonoperative management of clavicular fractures using the disabilities of the arm, shoulder and hand outcome measure., Timothy M Thormodsgard, Kayla Stone, David L Ciraulo, Matthew R Camuso, and Steven Desjardins

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An essential role for the circadian-regulated gene nocturnin in osteogenesis: the importance of local timekeeping in skeletal homeostasis., Anyonya R Guntur, Masanobu Kawai, Phuong Le, Mary L Bouxsein, Sheila Bornstein, Carla B Green, and Clifford J Rosen

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Congenital heart disease., Katherine Dolbec and Nathan W Mick

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Diagnosis and management of osteomyelitis., John Hatzenbuehler and Thomas J Pulling

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Regulation of non-classical FGF1 release and FGF-dependent cell transformation by CBF1-mediated notch signaling., Doreen Kacer, Christian McIntire, Alek Kirov, Erin Kany, Jennifer Roth, Lucy Liaw, Deena Small, Robert Friesel, Claudio Basilico, Francesca Tarantini, Joseph Verdi, and Igor Prudovsky

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The skeleton: a multi-functional complex organ: new insights into osteoblasts and their role in bone formation: the central role of PI3Kinase., Anyonya R Guntur and Clifford J Rosen

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Varieties of uncertainty in health care: a conceptual taxonomy., Paul K J Han, William M P Klein, and Neeraj K Arora

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Completion of adjuvant chemotherapy and use of health services for older women with epithelial ovarian cancer., Kathleen M Fairfield, Kimberly Murray, F Lee Lucas, Heidi R Wierman, Craig C Earle, Edward L Trimble, Laurie Small, and Joan L Warren

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A new view: tele-intensive care unit competencies, Susan F. Goran

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Preterm premature rupture of membranes ≥ 32 weeks' gestation: impact of revised practice guidelines., Arij Faksh, Joseph R Wax, F Lee Lucas, Angelina Cartin, and Michael G Pinette

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BMP signaling in the nephron progenitor niche., Leif Oxburgh, Aaron C Brown, Jennifer Fetting, and Beth Hill

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Correlation of angiographic late loss with neointimal proliferation in stents evaluated by OCT and histology in porcine coronary arteries., Jung-Sun Kim, David Wallace-Bradley, Carlos L Alviar, Gerard Conditt, Krzysztof Milewski, Maxwell E Afari, Yanping Cheng, Catalina Gallego, Armando Tellez, Gregg W Stone, Greg L Kaluza, and Juan F Granada

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Correlation of bivalirudin dose with creatinine clearance during treatment of heparin-induced thrombocytopenia., Courtney L Runyan, Katherine P Cabral, Richard R Riker, David Redding, Teresa May, David B Seder, Marizela Savic, Jacqueline Hedlund, Stuart Abramson, and Gilles L Fraser

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"See, feel, change"., Robert C Groom

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VDR haploinsufficiency impacts body composition and skeletal acquisition in a gender-specific manner., Francisco J A de Paula, Ingrid Dick-de-Paula, Sheila Bornstein, Bahman Rostama, Phuong Le, Sutada Lotinun, Roland Baron, and Clifford J Rosen

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New cardiac surgery programs established from 1993 to 2004 led to little increased access, substantial duplication of services., Frances Leslie Lucas, Andrea Siewers, David C Goodman, Dongmei Wang, and David E Wennberg

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Pediatric obesity: a review for the child psychiatrist., Ann E Maloney

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The interface of child mental health and juvenile diabetes mellitus., Sandra L Fritsch, Mark W Overton, and Douglas R Robbins

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Outcomes of 33 patients from the wars in Iraq and Afghanistan undergoing bilateral or bicompartmental craniectomy., Robert D Ecker, Lisa P Mulligan, Michael Dirks, Randy S Bell, Meryl A Severson, Robin S Howard, and Rocco A Armonda

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Preparing a research presentation: a guide for investigators., Joseph R Wax, Angelina Cartin, and Michael G Pinette

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Intussusception in traditional pediatric, nontraditional pediatric, and adult patients., Alexis A Cochran, George L Higgins, and Tania D Strout

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Prepare to be influenced., Robert C Groom

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Surface cooling after cardiac arrest: effectiveness, skin safety, and adverse events in routine clinical practice., Salam Jarrah, John Dziodzio, Christine Lord, Gilles L Fraser, Lee Lucas, Richard R Riker, and David B Seder

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The future nephrology workforce: will there be one?, Mark G Parker, Tod Ibrahim, Rachel Shaffer, Mitchell H Rosner, and Bruce A Molitoris

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Variation in arterial inflow temperature: a regional quality improvement project., Craig S Warren, Gordon R DeFoe, Robert C Groom, John W Pieroni, Candace S Groski, Catherine B Morse, Ellen M Connors, Peter J Lataille, Cathy S Ross, Donald S Likosky, and Northern New England Cardiovascular Disease Study Group

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Endoglin regulates cancer-stromal cell interactions in prostate tumors., Diana Romero, Christine O'Neill, Aleksandra Terzic, Liangru Contois, Kira Young, Barbara A Conley, Raymond C Bergan, Peter C Brooks, and Calvin P H Vary

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Multitarget test for emerging Lyme disease and anaplasmosis in a serosurvey of dogs, Maine, USA., Peter W Rand, Eleanor H Lacombe, Susan P Elias, Bruce K Cahill, Charles B Lubelczyk, and Robert P Smith

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Isolation and culture of cells from the nephrogenic zone of the embryonic mouse kidney., Aaron C Brown, Ulrika Blank, Derek C Adams, Michele J Karolak, Jennifer L Fetting, Beth L Hill, and Leif Oxburgh

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Early increases in concentrations of total, LDL, and HDL cholesterol in HIV-infected children following new exposure to antiretroviral therapy., Kevin A Sztam, Hongyu Jiang, Andrea Jurgrau, Richard J Deckelbaum, and Marc D Foca

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Explaining regional disparities in traffic mortality by decomposing conditional probabilities., Gregory P Goldstein, David E Clark, Lori L Travis, and Amy E Haskins

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RhoA-mediated signaling in Notch-induced senescence-like growth arrest and endothelial barrier dysfunction., Deepak Venkatesh, Natalie Fredette, Bahman Rostama, Yuefeng Tang, Calvin P H Vary, Lucy Liaw, and Sumithra Urs

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Communication of uncertainty regarding individualized cancer risk estimates: effects and influential factors., Paul K J Han, William M P Klein, Tom Lehman, Bill Killam, Holly Massett, and Andrew N Freedman

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Future directions of stroke prevention in atrial fibrillation: the potential impact of novel anticoagulants and stroke risk stratification., K P Cabral, J Ansell, and E M Hylek

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Measuring quality and the story of beta blockers., Jens Eldrup-Jorgensen

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Prevention of the first episode of psychosis., William R McFarlane

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Temperatures rising: brown fat and bone., Katherine J Motyl and Clifford J Rosen

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Emerging therapeutic opportunities for skeletal restoration., Masanobu Kawai, Ulrike I Mödder, Sundeep Khosla, and Clifford J Rosen

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Hypertension after kidney transplant., Mahendra Mangray and John P Vella

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Intraprocedural tissue diagnosis during ERCP employing a new cytology preparation of forceps biopsy (Smash protocol)., Eric R Wright, Gennadiy Bakis, Ramesh Srinivasan, Ramu Raju, Harsha Vittal, Michael K Sanders, Kirk Bernadino, Hagen Blaszyk, and Douglas A Howell

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Multiple clinical practice guidelines for breast and cervical cancer screening: perceptions of US primary care physicians., Paul K J Han, Carrie N Klabunde, Nancy Breen, Gigi Yuan, Alyssa Grauman, William W Davis, and Stephen H Taplin

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Transdermal nicotine replacement therapy in cigarette smokers with acute subarachnoid hemorrhage., David B Seder, J Michael Schmidt, Neeraj Badjatia, Luis Fernandez, Fred Rincon, Jan Claassen, Errol Gordon, Emmanuel Carrera, Pedro Kurtz, Kiwon Lee, E Sander Connolly, and Stephan A Mayer

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Clinical practice. Vitamin D insufficiency., Clifford J Rosen

An overview of cognitive-behavioral management of memory dysfunction associated with chemotherapy. [Spanish]., Robert J. Ferguson and Amber A. Martinson

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A systematic review of the use and effectiveness of the Objective Structured Teaching Encounter., Robert L Trowbridge, Laura K Snydman, Jenny Skolfield, Janet Hafler, and Robert G Bing-You

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Building a System of Care: Integration across the Heart Failure Care Continuum., Jackie Cawley and Cassandra Cote Grantham

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Development of a safe and pragmatic awake craniotomy program at Maine Medical Center., Anand I Rughani, Theodor Rintel, Rajiv Desai, Deborah A Cushing, and Jeffrey E Florman

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Mechanisms of TGF-β-induced differentiation in human vascular smooth muscle cells., Yuefeng Tang, Xuehui Yang, Robert E Friesel, Calvin P H Vary, and Lucy Liaw

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Medullary thyroid cancer: an update of new guidelines and recent developments., Leslie S Wu, Sanziana A Roman, and Julie A Sosa

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Testing the sensitivity, specificity and feasibility of four falls risk assessment tools in a clinical setting., Joanne Chapman, Deborah Bachand, and Kristiina Hyrkäs

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Uncovering child abuse., Catherine Lyden

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Uncovering child abuse., Catherine Lyden

Submissions from 2010

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Follistatin-like 1 regulates renal IL-1β expression in cisplatin nephrotoxicity., Derek C Adams, Michele J Karolak, Barry W Larman, Lucy Liaw, James D Nolin, and Leif Oxburgh

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Perspectives on the experience of being physically restrained: an integrative review of the qualitative literature., Tania D Strout

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The prize., Robert C Groom

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Two novel human NUMB isoforms provide a potential link between development and cancer., Aldona Karaczyn, Mahmud Bani-Yaghoub, Roger Tremblay, Chris Kubu, Rebecca Cowling, Tamara L Adams, Igor Prudovsky, Douglas Spicer, Robert Friesel, Calvin Vary, and Joseph M Verdi

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Micro-mismanaging sickle cell stress., Don M Wojchowski

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Olanzapine approved for the acute treatment of schizophrenia or manic/mixed episodes associated with bipolar I disorder in adolescent patients., Ann E Maloney and Linmarie Sikich

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Novel insights into the relationship between diabetes and osteoporosis., Francisco J A de Paula, Mark C Horowitz, and Clifford J Rosen

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PPARγ: a circadian transcription factor in adipogenesis and osteogenesis., Masanobu Kawai and Clifford J Rosen

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Risk management and avoiding legal pitfalls in the emergency treatment of high-risk orthopedic injuries., Carl A Germann and Andrew D Perron

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Same admission cardiac catheterization and cardiac surgery: is there an increased incidence of acute kidney injury?, Robert S Kramer, Reed D Quinn, Robert C Groom, John H Braxton, David J Malenka, Mirle A Kellett, Jeremiah R Brown, and Northern New England Cardiovascular Disease Study Group

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The general surgery residency at Maine Medical Center., Ajita S Prabhu, Jonathan F Dreifus, and James F Whiting

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Barriers to outdoor physical activity in wintertime among Somali youth., Elizabeth Rothe, Christina Holt, Celine Kuhn, Timothy McAteer, Isabella Askari, Mary O'Meara, Abdimajid Sharif, and William Dexter

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Culture Change through Patient Engagement, Bettyanne Grant and Sandra H. Colello

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Fabry disease complicating pregnancy., Emily Parent, Joseph R Wax, Wendy Smith, Hagen Blaszyk, Michael G Pinette, Angelina Cartin, and Jacquelyn Blackstone

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Placebo-controlled trials in osteoporosis--proceeding with caution., Clifford J Rosen and Sundeep Khosla

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Smoking during pregnancy and risk of abnormal glucose tolerance: a prospective cohort study., Amy E Haskins, Elizabeth R Bertone-Johnson, Penelope Pekow, Elena Carbone, Renée T Fortner, and Lisa Chasan-Taber

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Acute stroke from air embolism after leg sclerotherapy., Matthew C Delaney, Christopher T Bowe, and George L Higgins

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Approach to the diagnosis and treatment of vulvar pain., Claire S Danby and Lynette J Margesson

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Idiopathic ventricular tachycardia: belhassen type., Thomas W Quimby, Ariel A Clark, and Megan L Fix

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Implementing an electronic point-of-care medical record at an organized athletic event: challenges, pitfalls, and lessons learned., Hamilton J Wells, George L Higgins, and Michael R Baumann

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Maternal and newborn outcomes in planned home birth vs planned hospital births: a metaanalysis., Joseph R Wax, F Lee Lucas, Maryanne Lamont, Michael G Pinette, Angelina Cartin, and Jacquelyn Blackstone

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Minireview: A skeleton in serotonin's closet?, Masanobu Kawai and Clifford J Rosen

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The contribution of the Tie2+ lineage to primitive and definitive hematopoietic cells., Yuefeng Tang, Anne Harrington, Xuehui Yang, Robert E Friesel, and Lucy Liaw

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The IGF-I regulatory system and its impact on skeletal and energy homeostasis., Masanobu Kawai and Clifford J Rosen

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The use of intraoperative cholangiogram during laparoscopic double cholecystectomy., Gustavo E Guajardo-Salinas, Maria L Martinez-Ugarte, and Georges Abourjaily

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Understanding qualitative evidence for emergency nursing practice., Tania D Strout

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Revisiting the rosiglitazone story--lessons learned., Clifford J Rosen

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A second set of eyes: An introduction to Tele-ICU., Susan F Goran

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Effect of the perioperative blood transfusion and blood conservation in cardiac surgery clinical practice guidelines of the Society of Thoracic Surgeons and the Society of Cardiovascular Anesthesiologists upon clinical practices., Donald S Likosky, Daniel C FitzGerald, Robert C Groom, Dwayne K Jones, Robert A Baker, Kenneth G Shann, C David Mazer, Bruce D Spiess, and Simon C Body

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Predicting risk-adjusted mortality for trauma patients: logistic versus multilevel logistic models., David E Clark, Edward L Hannan, and Chuntao Wu

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Prenatal sonographic diagnosis of a perineal lipoma., Joseph R Wax, Michael G Pinette, Baird Mallory, Molly Carpenter, Steven Winn, and Angelina Cartin

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Risk profiles of progression in primary focal segmental glomerulosclerosis., Lori L Travis and James C M Chan

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Exploring and evaluating five paediatric falls assessment instruments and injury risk indicators: an ambispective study in a tertiary care setting., Kimberly Harvey, Debra Kramlich, Joanne Chapman, Jeanne Parker, and Elizabeth Blades

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Kidney allograft biopsy: timing to complications., Z Yablon, P Recupero, J McKenna, J Vella, and M G Parker

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Nephrology training in the 21st century: toward outcomes-based education., Mark G Parker

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The many facets of PPARgamma: novel insights for the skeleton., Masanobu Kawai, Kyle M Sousa, Ormond A MacDougald, and Clifford J Rosen

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Trial of a minimal-risk botanical compound to control the vector tick of Lyme disease., Peter W Rand, Eleanor H Lacombe, Susan P Elias, Charles B Lubelczyk, Theodore St Amand, and Robert P Smith

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Notch and transforming growth factor-beta (TGFbeta) signaling pathways cooperatively regulate vascular smooth muscle cell differentiation., Yuefeng Tang, Sumithra Urs, Joshua Boucher, Tyler Bernaiche, Deepak Venkatesh, Douglas B Spicer, Calvin P H Vary, and Lucy Liaw

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Poison center surveillance data: the good, the bad and ... the flu., Karen E Simone and Henry A Spiller

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The effect of the perioperative blood transfusion and blood conservation in cardiac surgery Clinical Practice Guidelines of the Society of Thoracic Surgeons and the Society of Cardiovascular Anesthesiologists upon clinical practices., Donald S Likosky, Daniel C FitzGerald, Robert C Groom, Dwayne K Jones, Robert A Baker, Kenneth G Shann, C David Mazer, Bruce D Spiess, and Simon C Body

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Variation is opportunity!, Robert C Groom

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Back to the future: revisiting parathyroid hormone and calcitonin control of bone remodeling., F J A de Paula and C J Rosen

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Injury trends and prevention in rugby union football., Amy E MacQueen and William W Dexter

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Portland identification and early referral: a community-based system for identifying and treating youths at high risk of psychosis., William R McFarlane, William L Cook, Donna Downing, Mary B Verdi, Kristen A Woodberry, and Anita Ruff

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What is the role of lidocaine or phenytoin in tricyclic antidepressant-induced cardiotoxicity?, Anthony Foianini, Timothy Joseph Wiegand, and Neal Benowitz

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Colorectal cancer screening pilot program for underserved women in Cumberland County, Maine., Susan Miesfeldt, Christine Hayden, Netta Apedoe, Sharon Jerome, and Andrea Fletcher

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Pediatric obesity: a review for the child psychiatrist., Ann E Maloney

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Preface: Interface between pediatrics and children's mental health., Sandra L Fritsch

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Psychiatric features in children with genetic syndromes: toward functional phenotypes., Matthew S Siegel and Wendy E Smith