Incorporated in 1868, MMC is the state’s largest medical center, licensed for 700 beds and employing more than 9,600 people. Maine Medical Center’s unique role as both a community hospital and a referral center requires an unparalleled depth and breadth of services, including the state’s only allopathic medical school program, through a partnership with Tufts University School of Medicine, and a world-class biomedical research center, the MaineHealth Institute for Research.

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Submissions from 2011

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Explaining regional disparities in traffic mortality by decomposing conditional probabilities., Gregory P Goldstein, David E Clark, Lori L Travis, and Amy E Haskins

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RhoA-mediated signaling in Notch-induced senescence-like growth arrest and endothelial barrier dysfunction., Deepak Venkatesh, Natalie Fredette, Bahman Rostama, Yuefeng Tang, Calvin P H Vary, Lucy Liaw, and Sumithra Urs

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Communication of uncertainty regarding individualized cancer risk estimates: effects and influential factors., Paul K J Han, William M P Klein, Tom Lehman, Bill Killam, Holly Massett, and Andrew N Freedman

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Future directions of stroke prevention in atrial fibrillation: the potential impact of novel anticoagulants and stroke risk stratification., K P Cabral, J Ansell, and E M Hylek

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Measuring quality and the story of beta blockers., Jens Eldrup-Jorgensen

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Prevention of the first episode of psychosis., William R McFarlane

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Temperatures rising: brown fat and bone., Katherine J Motyl and Clifford J Rosen

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Emerging therapeutic opportunities for skeletal restoration., Masanobu Kawai, Ulrike I Mödder, Sundeep Khosla, and Clifford J Rosen

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Hypertension after kidney transplant., Mahendra Mangray and John P Vella

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Intraprocedural tissue diagnosis during ERCP employing a new cytology preparation of forceps biopsy (Smash protocol)., Eric R Wright, Gennadiy Bakis, Ramesh Srinivasan, Ramu Raju, Harsha Vittal, Michael K Sanders, Kirk Bernadino, Hagen Blaszyk, and Douglas A Howell

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Multiple clinical practice guidelines for breast and cervical cancer screening: perceptions of US primary care physicians., Paul K J Han, Carrie N Klabunde, Nancy Breen, Gigi Yuan, Alyssa Grauman, William W Davis, and Stephen H Taplin

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Transdermal nicotine replacement therapy in cigarette smokers with acute subarachnoid hemorrhage., David B Seder, J Michael Schmidt, Neeraj Badjatia, Luis Fernandez, Fred Rincon, Jan Claassen, Errol Gordon, Emmanuel Carrera, Pedro Kurtz, Kiwon Lee, E Sander Connolly, and Stephan A Mayer

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Clinical practice. Vitamin D insufficiency., Clifford J Rosen

An overview of cognitive-behavioral management of memory dysfunction associated with chemotherapy. [Spanish]., Robert J. Ferguson and Amber A. Martinson

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A systematic review of the use and effectiveness of the Objective Structured Teaching Encounter., Robert L Trowbridge, Laura K Snydman, Jenny Skolfield, Janet Hafler, and Robert G Bing-You

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Building a System of Care: Integration across the Heart Failure Care Continuum., Jackie Cawley and Cassandra Cote Grantham

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Development of a safe and pragmatic awake craniotomy program at Maine Medical Center., Anand I Rughani, Theodor Rintel, Rajiv Desai, Deborah A Cushing, and Jeffrey E Florman

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Mechanisms of TGF-β-induced differentiation in human vascular smooth muscle cells., Yuefeng Tang, Xuehui Yang, Robert E Friesel, Calvin P H Vary, and Lucy Liaw

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Medullary thyroid cancer: an update of new guidelines and recent developments., Leslie S Wu, Sanziana A Roman, and Julie A Sosa

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Testing the sensitivity, specificity and feasibility of four falls risk assessment tools in a clinical setting., Joanne Chapman, Deborah Bachand, and Kristiina Hyrkäs

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Uncovering child abuse., Catherine Lyden

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Uncovering child abuse., Catherine Lyden

Submissions from 2010

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Follistatin-like 1 regulates renal IL-1β expression in cisplatin nephrotoxicity., Derek C Adams, Michele J Karolak, Barry W Larman, Lucy Liaw, James D Nolin, and Leif Oxburgh

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Perspectives on the experience of being physically restrained: an integrative review of the qualitative literature., Tania D Strout

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The prize., Robert C Groom

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Two novel human NUMB isoforms provide a potential link between development and cancer., Aldona Karaczyn, Mahmud Bani-Yaghoub, Roger Tremblay, Chris Kubu, Rebecca Cowling, Tamara L Adams, Igor Prudovsky, Douglas Spicer, Robert Friesel, Calvin Vary, and Joseph M Verdi

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Micro-mismanaging sickle cell stress., Don M Wojchowski

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Olanzapine approved for the acute treatment of schizophrenia or manic/mixed episodes associated with bipolar I disorder in adolescent patients., Ann E Maloney and Linmarie Sikich

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Novel insights into the relationship between diabetes and osteoporosis., Francisco J A de Paula, Mark C Horowitz, and Clifford J Rosen

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PPARγ: a circadian transcription factor in adipogenesis and osteogenesis., Masanobu Kawai and Clifford J Rosen

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Risk management and avoiding legal pitfalls in the emergency treatment of high-risk orthopedic injuries., Carl A Germann and Andrew D Perron

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Same admission cardiac catheterization and cardiac surgery: is there an increased incidence of acute kidney injury?, Robert S Kramer, Reed D Quinn, Robert C Groom, John H Braxton, David J Malenka, Mirle A Kellett, Jeremiah R Brown, and Northern New England Cardiovascular Disease Study Group

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The general surgery residency at Maine Medical Center., Ajita S Prabhu, Jonathan F Dreifus, and James F Whiting

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Barriers to outdoor physical activity in wintertime among Somali youth., Elizabeth Rothe, Christina Holt, Celine Kuhn, Timothy McAteer, Isabella Askari, Mary O'Meara, Abdimajid Sharif, and William Dexter

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Culture Change through Patient Engagement, Bettyanne Grant and Sandra H. Colello

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Fabry disease complicating pregnancy., Emily Parent, Joseph R Wax, Wendy Smith, Hagen Blaszyk, Michael G Pinette, Angelina Cartin, and Jacquelyn Blackstone

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Placebo-controlled trials in osteoporosis--proceeding with caution., Clifford J Rosen and Sundeep Khosla

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Smoking during pregnancy and risk of abnormal glucose tolerance: a prospective cohort study., Amy E Haskins, Elizabeth R Bertone-Johnson, Penelope Pekow, Elena Carbone, Renée T Fortner, and Lisa Chasan-Taber

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Acute stroke from air embolism after leg sclerotherapy., Matthew C Delaney, Christopher T Bowe, and George L Higgins

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Approach to the diagnosis and treatment of vulvar pain., Claire S Danby and Lynette J Margesson

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Idiopathic ventricular tachycardia: belhassen type., Thomas W Quimby, Ariel A Clark, and Megan L Fix

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Implementing an electronic point-of-care medical record at an organized athletic event: challenges, pitfalls, and lessons learned., Hamilton J Wells, George L Higgins, and Michael R Baumann

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Maternal and newborn outcomes in planned home birth vs planned hospital births: a metaanalysis., Joseph R Wax, F Lee Lucas, Maryanne Lamont, Michael G Pinette, Angelina Cartin, and Jacquelyn Blackstone

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Minireview: A skeleton in serotonin's closet?, Masanobu Kawai and Clifford J Rosen

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The contribution of the Tie2+ lineage to primitive and definitive hematopoietic cells., Yuefeng Tang, Anne Harrington, Xuehui Yang, Robert E Friesel, and Lucy Liaw

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The IGF-I regulatory system and its impact on skeletal and energy homeostasis., Masanobu Kawai and Clifford J Rosen

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The use of intraoperative cholangiogram during laparoscopic double cholecystectomy., Gustavo E Guajardo-Salinas, Maria L Martinez-Ugarte, and Georges Abourjaily

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Understanding qualitative evidence for emergency nursing practice., Tania D Strout

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Revisiting the rosiglitazone story--lessons learned., Clifford J Rosen

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A second set of eyes: An introduction to Tele-ICU., Susan F Goran

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Effect of the perioperative blood transfusion and blood conservation in cardiac surgery clinical practice guidelines of the Society of Thoracic Surgeons and the Society of Cardiovascular Anesthesiologists upon clinical practices., Donald S Likosky, Daniel C FitzGerald, Robert C Groom, Dwayne K Jones, Robert A Baker, Kenneth G Shann, C David Mazer, Bruce D Spiess, and Simon C Body

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Predicting risk-adjusted mortality for trauma patients: logistic versus multilevel logistic models., David E Clark, Edward L Hannan, and Chuntao Wu

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Prenatal sonographic diagnosis of a perineal lipoma., Joseph R Wax, Michael G Pinette, Baird Mallory, Molly Carpenter, Steven Winn, and Angelina Cartin

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Risk profiles of progression in primary focal segmental glomerulosclerosis., Lori L Travis and James C M Chan

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Exploring and evaluating five paediatric falls assessment instruments and injury risk indicators: an ambispective study in a tertiary care setting., Kimberly Harvey, Debra Kramlich, Joanne Chapman, Jeanne Parker, and Elizabeth Blades

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Kidney allograft biopsy: timing to complications., Z Yablon, P Recupero, J McKenna, J Vella, and M G Parker

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Nephrology training in the 21st century: toward outcomes-based education., Mark G Parker

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The many facets of PPARgamma: novel insights for the skeleton., Masanobu Kawai, Kyle M Sousa, Ormond A MacDougald, and Clifford J Rosen

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Trial of a minimal-risk botanical compound to control the vector tick of Lyme disease., Peter W Rand, Eleanor H Lacombe, Susan P Elias, Charles B Lubelczyk, Theodore St Amand, and Robert P Smith

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Notch and transforming growth factor-beta (TGFbeta) signaling pathways cooperatively regulate vascular smooth muscle cell differentiation., Yuefeng Tang, Sumithra Urs, Joshua Boucher, Tyler Bernaiche, Deepak Venkatesh, Douglas B Spicer, Calvin P H Vary, and Lucy Liaw

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Poison center surveillance data: the good, the bad and ... the flu., Karen E Simone and Henry A Spiller

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The effect of the perioperative blood transfusion and blood conservation in cardiac surgery Clinical Practice Guidelines of the Society of Thoracic Surgeons and the Society of Cardiovascular Anesthesiologists upon clinical practices., Donald S Likosky, Daniel C FitzGerald, Robert C Groom, Dwayne K Jones, Robert A Baker, Kenneth G Shann, C David Mazer, Bruce D Spiess, and Simon C Body

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Variation is opportunity!, Robert C Groom

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Back to the future: revisiting parathyroid hormone and calcitonin control of bone remodeling., F J A de Paula and C J Rosen

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Injury trends and prevention in rugby union football., Amy E MacQueen and William W Dexter

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Portland identification and early referral: a community-based system for identifying and treating youths at high risk of psychosis., William R McFarlane, William L Cook, Donna Downing, Mary B Verdi, Kristen A Woodberry, and Anita Ruff

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What is the role of lidocaine or phenytoin in tricyclic antidepressant-induced cardiotoxicity?, Anthony Foianini, Timothy Joseph Wiegand, and Neal Benowitz

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Colorectal cancer screening pilot program for underserved women in Cumberland County, Maine., Susan Miesfeldt, Christine Hayden, Netta Apedoe, Sharon Jerome, and Andrea Fletcher

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Pediatric obesity: a review for the child psychiatrist., Ann E Maloney

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Preface: Interface between pediatrics and children's mental health., Sandra L Fritsch

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Psychiatric features in children with genetic syndromes: toward functional phenotypes., Matthew S Siegel and Wendy E Smith

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Systeme International in the ICU in the United States., David E Clark and Paul F Laeseke

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The interface of child mental health and juvenile diabetes mellitus., Sandra L Fritsch, Mark W Overton, and Douglas R Robbins

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Tick (Acari: Ixodidae) infestation at two rural, seasonal camps in Maine and Vermont., C Lubelczyk, B K Cahill, T Hanson, J Turmel, E Lacombe, P W Rand, S P Elias, and R P Smith

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Using a hierarchical model to estimate risk-adjusted mortality for hospitals not included in the reference sample., David E Clark, Edward L Hannan, and Stephen W Raudenbush

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Using decentralized medical education to address the workforce needs of a rural state: a partnership between Maine Medical Center and Tufts University school of medicine., Robert G Bing-You, Peter W Bates, Scott K Epstein, Amy B Kuhlik, and Thomas E Norris

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Using decentralized medical education to address the workforce needs of a rural state: a partnership between Maine Medical Center and Tufts University school of medicine., Robert G Bing-You, Peter W Bates, Scott K Epstein, Amy B Kuhlik, and Thomas E Norris

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Adulterated cocaine and lessons learned from the Jake walk blues., Timothy J Wiegand

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Cognitive effects of cancer chemotherapy in adult cancer survivors: Cognitive-behavioral management., Robert J. Ferguson, Anna G. Cassel, and Rachel F.S. Dawson

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Endoglin phosphorylation by ALK2 contributes to the regulation of prostate cancer cell migration., Diana Romero, Aleksandra Terzic, Barbara A Conley, Clarissa S Craft, Borko Jovanovic, Raymond C Bergan, and Calvin P H Vary

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Microemboli from cardiopulmonary bypass are associated with a serum marker of brain injury., Robert C Groom, Reed D Quinn, Paul Lennon, Janine Welch, Robert S Kramer, Cathy S Ross, Peter A Beaulieu, Jeremiah R Brown, David J Malenka, Gerald T O'Connor, Donald S Likosky, and Northern New England Cardiovascular Disease Study Group

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Nocturnin: a circadian target of Pparg-induced adipogenesis., Masanobu Kawai, Carla B Green, Mark Horowitz, Cheryl Ackert-Bicknell, Beata Lecka-Czernik, and Clifford J Rosen

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BMP4 regulates vascular progenitor development in human embryonic stem cells through a Smad-dependent pathway., Hao Bai, Yongxing Gao, Melanie Arzigian, Don M Wojchowski, Wen-Shu Wu, and Zack Z Wang

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Bone: adiposity and bone accrual-still an established paradigm?, Masanobu Kawai and Clifford J Rosen

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Gene-delivery systems for iPS cell generation., Lijian Shao and Wen-Shu Wu

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How to meet national quality initiatives: best practices., Katherine Phillips Cabral

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Hyponatremia increases mortality in pediatric patients listed for liver transplantation., Rebecca G Carey, John C Bucuvalas, William F Balistreri, Todd G Nick, Frederick R Ryckman, and Nada Yazigi

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Perceptions of high-risk care and barriers to care among women at risk for hereditary breast and ovarian cancer following genetic counseling in the community setting., Debra Morgan, Heather Sylvester, F Lee Lucas, and Susan Miesfeldt

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A role for NRAGE in NF-kappaB activation through the non-canonical BMP pathway., Nicholas Matluk, Jennifer A Rochira, Aldona Karaczyn, Tamara Adams, and Joseph M Verdi

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Payment reform--the need to harmonize approaches in Medicare and the private sector., Peter V Lee, Robert A Berenson, and John Tooker

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Hereditary breast and ovarian cancer: referral source for genetic assessment and communication regarding assessment with nongenetic clinicians in the community setting., Debra Morgan, Heather Sylvester, Frances Lee Lucas, and Susan Miesfeldt

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Macronutrient supplementation and food prices in HIV treatment., Kevin A Sztam, Wafaie W Fawzi, and Christopher Duggan

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Spirit & Practice, Maine Medical Center

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The coordination of primary and oncology specialty care at the end of life., Paul K J Han and Daniel Rayson