Incorporated in 1868, MMC is the state’s largest medical center, licensed for 700 beds and employing more than 9,600 people. MaineHealth Maine Medical Center’s unique role as both a community hospital and a referral center requires an unparalleled depth and breadth of services, including the state’s only allopathic medical school program, through a partnership with Tufts University School of Medicine, and a world-class biomedical research center, the MaineHealth Institute for Research.

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Submissions from 2013

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The effect of medical students and residents on measures of efficiency and timeliness in an academic medical center emergency department., Matthew DeLaney, Kate D Zimmerman, Tania D Strout, and Megan L Fix

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Interactive 3D analysis of blood vessel trees and collateral vessel volumes in magnetic resonance angiograms in the mouse ischemic hindlimb model., Peter C Marks, Marilena Preda, Terry Henderson, Lucy Liaw, Volkhard Lindner, Robert E Friesel, and Ilka M Pinz

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IGF-1 regulation of key signaling pathways in bone., Anyonya R Guntur and Clifford J Rosen

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Acute complications of movement disorders surgery: effects of age and comorbidities., Anand I Rughani, Mojgan Hodaie, and Andres M Lozano

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Dietary calcium from dairy and nondairy sources, and risk of symptomatic kidney stones., Eric N Taylor and Gary C Curhan

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Educational agenda for diagnostic error reduction., Robert L Trowbridge, Gurpreet Dhaliwal, and Karen S Cosby

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Impact of Let's Go! 5-2-1-0: a community-based, multisetting childhood obesity prevention program., Victoria W Rogers, Patricia H Hart, Elizabeth Motyka, Emily N Rines, Jackie Vine, and Deborah A Deatrick

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Sex-specific association of a common variant of the XG gene with autism spectrum disorders., Shun-Chiao Chang, David L Pauls, Christoph Lange, Roksana Sasanfar, and Susan L Santangelo

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Sprouty4 regulates endothelial cell migration via modulating integrin β3 stability through c-Src., Yan Gong, Xuehui Yang, Qing He, Lindsey Gower, Igor Prudovsky, Calvin P H Vary, Peter C Brooks, and Robert E Friesel

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TMEFF2 and SARDH cooperate to modulate one-carbon metabolism and invasion of prostate cancer cells., Thomas Green, Xiaofei Chen, Stephen Ryan, Adam S Asch, and Maria J Ruiz-Echevarría

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Telephone administration of the aberrant behavior checklist: a pilot study of feasibility in children with intellectual disability and autism., Matthew Siegel, Briana Milligan, Hannah Stein, Olivia Teer, and Kahsi A Smith

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The value of personalised risk information: a qualitative study of the perceptions of patients with prostate cancer., Paul K J Han, Norbert Hootsmans, Michael Neilson, Bethany Roy, Terence Kungel, Caitlin Gutheil, Michael Diefenbach, and Moritz Hansen

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Patient safety in the cardiac operating room: human factors and teamwork: a scientific statement from the American Heart Association., Joyce A Wahr, Richard L Prager, J H Abernathy, Elizabeth A Martinez, Eduardo Salas, Patricia C Seifert, Robert C Groom, Bruce D Spiess, Bruce E Searles, Thoralf M Sundt, Juan A Sanchez, Scott A Shappell, Michael H Culig, Elizabeth H Lazzara, David C Fitzgerald, Vinod H Thourani, Pirooz Eghtesady, John S Ikonomidis, Michael R England, Frank W Sellke, Nancy A Nussmeier, and American Heart Association Council on Cardiovascular on Quality of Care and Outcomes Research

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Altered thermogenesis and impaired bone remodeling in Misty mice., Katherine J Motyl, Kathleen A Bishop, Victoria E DeMambro, Sheila A Bornstein, Phuong Le, Masanobu Kawai, Sutada Lotinun, Mark C Horowitz, Roland Baron, Mary L Bouxsein, and Clifford J Rosen

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Mediastinal teratoma diagnosed via ultrasound-guided biopsy., Elena L Resnick, Jennifer M Talmadge, and Steven S Winn

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Test- Management of the base of the appendix in pediatric laparoscopic appendectomy: clip, ligate, or staple?, Monica Langer, Arash Safavi, and Erik D Skarsgard

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The path to best care., Robert C Groom

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Stent healing response following delivery of paclitaxel via durable polymeric matrix versus iopromide-based balloon coating in the familial hypercholesterolaemic swine model of coronary injury., Piotr P Buszman, Armando Tellez, Maxwell Afari, Yanping Cheng, Gerard B Conditt, Jennifer C McGregor, Krzysztof Milewski, Mark Stenoien, Greg L Kaluza, and Juan F Granada

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Effect of chronic oral anticoagulation with warfarin on the durability and outcomes of endovascular aortic aneurysm repair., Marques S Johnson, Jasmine Chiang, Jens Eldrup-Jorgensen, David E Clark, and Christopher T Healey

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Lesser trochanter avulsion fracture., Nicholas C Papacostas, Christopher T Bowe, and Tania D Shaffer Strout

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Tissue uptake, distribution, and healing response after delivery of paclitaxel via second-generation iopromide-based balloon coating: a comparison with the first-generation technology in the iliofemoral porcine model., Piotr P Buszman, Armando Tellez, Maxwell E Afari, Athanasios Peppas, Gerard B Conditt, Serge D Rousselle, Jennifer C McGregor, Mark Stenoien, Greg L Kaluza, and Juan F Granada

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Common misconceptions about vitamin D--implications for clinicians., Clifford J Rosen and Christine L Taylor

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National evidence on the use of shared decision making in prostate-specific antigen screening., Paul K J Han, Sarah Kobrin, Nancy Breen, Djenaba A Joseph, Jun Li, Dominick L Frosch, and Carrie N Klabunde

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Predictive value of the Pediatric Ulcerative Colitis Activity Index in the surgical management of ulcerative colitis., Fabienne L Gray, Christopher G Turner, David Zurakowski, Athos Bousvaros, Bradley C Linden, Robert C Shamberger, and Craig W Lillehei

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SPECT vs CT: CT is not the first line test for the diagnosis and prognosis of stable coronary artery disease., Zachary J Trzaska and Mylan C Cohen

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The SNAI1 and SNAI2 proteins occupy their own and each other's promoter during chondrogenesis., Ying Chen and Thomas Gridley

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Carotid artery endarterectomy: a multidisciplinary approach to improving resource utilization and quality assurance., Jill A Knutson, Carol Jo Morse, Jens Eldrup-Jorgensen, Margaret Estee, Lois Hayworth, Tara A Herman, and Angela S Vereshko

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Closure of tubular patent ductus arteriosus in infants with the Amplatzer Vascular Plug II., Abby A R Gross and Jon P Donnelly

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Compensatory regulation of the Snai1 and Snai2 genes during chondrogenesis., Ying Chen and Thomas Gridley

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Pediatric postoperative intussusception in the minimally invasive surgery era: a 13-year, single center experience., Justin D Klein, Christopher G Turner, Sophia C Kamran, Alvin Y C Yu, Lynne Ferrari, David Zurakowski, and Dario O Fauza

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Combating infections at Maine Medical Center: Insights into complexity-informed leadership from positive deviance, Curt Lindberg and Margaritte Schneider

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HELP© prevent falls by preventing delirium., Rhonda L Babine, Stacey Farrington, and Heidi R Wierman

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Historic condition in a modern child with autism., Megan Berube, Carol Hubbard, Leah Mallory, Eric Larsen, Peter Morrison, and Marilyn Augustyn

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Managing blunt trauma in patients receiving dabigatran etexilate: case study and review of the literature., Peter Eamonn Croft, Katherine P Cabral, Tania D Strout, Michael R Baumann, Michael A Gibbs, and Matthew C Delaney

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Periurethral aggressive angiomyxoma: a case report., Caroline Foust-Wright, Arielle Allen, and S Abbas Shobeiri

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Aorto-mesenteric and renal allograft transplant: a novel treatment for midaortic syndrome., K Vakili, N M Fullington, C G Turner, R P Cauley, K M Potanos, S Lee, M Ferguson, J E Lock, and H B Kim

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Congenital hypothyroidism., Heather J Shanholtz

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ErbB/integrin signaling interactions in regulation of myocardial cell-cell and cell-matrix interactions., Laura Pentassuglia and Douglas B Sawyer

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Notch1 activation in embryonic VE-cadherin populations selectively blocks hematopoietic stem cell generation and fetal liver hematopoiesis., Yuefeng Tang, Hao Bai, Sumithra Urs, Zack Wang, and Lucy Liaw

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Physicians' beliefs about breast cancer surveillance testing are consistent with test overuse., Paul K J Han, Carrie N Klabunde, Anne-Michelle Noone, Craig C Earle, John Z Ayanian, Patricia A Ganz, Katherine S Virgo, and Arnold L Potosky

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Type 1 diabetes mellitus abrogates compensatory augmentation of myocardial neuregulin-1β/ErbB in response to myocardial infarction resulting in worsening heart failure., Oghenerukevwe Odiete, Ewa A Konik, Douglas B Sawyer, and Michael F Hill

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Role for compartmentalization in nephron progenitor differentiation., Aaron C Brown, Sree Deepthi Muthukrishnan, Justin A Guay, Derek C Adams, Dillon A Schafer, Jennifer L Fetting, and Leif Oxburgh

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Kit for Detecting CTHRC1 in a Sample, Volkhard Lindner, Ilka Pinz, and Julia Patrizia Stohn

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Blistering rash in an older man., Nathaniel J Ward and Casey Z MacVane

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Bone Remodeling and Energy Metabolism: New Perspectives., Francisco J A de Paula and Clifford J Rosen

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Challenges implementing bar-coded medication administration in the emergency room in comparison to medical surgical units., Nancy Glover

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Development and impact of human papillomavirus vaccines., Christopher J Darus and Jennifer J Mueller

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Educational Exhibit Abstract No. 294. Financial impact of a resident-run vascular and interventional radiology clinic, Matthew Recker, K Cicuto, Pablo Kim, and D Mittleider

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Management of genetic syndromes predisposing to gynecologic cancers., Susan Miesfeldt, Amanda Lamb, and Christine Duarte

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Racial disparities in survival among injured drivers., Amy E Haskins, David E Clark, and Lori L Travis

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Single-dose etomidate is not associated with increased mortality in ICU patients with sepsis: analysis of a large electronic ICU database., Laura C McPhee, Omar Badawi, Gilles L Fraser, Patricia A Lerwick, Richard R Riker, Ilene H Zuckerman, Christine Franey, and David B Seder

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The power of partnerships., Robert C Groom

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Nonclassically secreted regulators of angiogenesis., Igor Prudovsky

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The amniotic fluid as a source of neural stem cells in the setting of experimental neural tube defects., Christopher G Turner, Justin D Klein, Junmei Wang, Devang Thakor, Darcy Benedict, Azra Ahmed, Yang D Teng, and Dario O Fauza

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Protein-phospholipid interactions in nonclassical protein secretion: problem and methods of study., Igor Prudovsky, Thallapuranam Krishnaswamy Suresh Kumar, Sarah Sterling, and David Neivandt

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Conceptual, methodological, and ethical problems in communicating uncertainty in clinical evidence., Paul K. Han

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Conceptual, methodological, and ethical problems in communicating uncertainty in clinical evidence., Paul K J Han

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Generalized weakness in the geriatric emergency department patient: an approach to initial management., Robert S Anderson and Sarah A M Hallen

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Hyperperfusion syndrome after stent/coiling of a ruptured carotid bifurcation aneurysm., Robert D Ecker, Richard D Murray, and David B Seder

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Voices of family members and significant others in the tele-intensive care unit, Mary Jahrsdoerfer and Susan Goran

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An epizootic of eastern equine encephalitis virus, Maine, USA in 2009: outbreak description and entomological studies., Charles Lubelczyk, John-Paul Mutebi, Sara Robinson, Susan P Elias, Leticia B Smith, Sherrie A Juris, Kimberly Foss, Anne Lichtenwalner, Kirk J Shively, Donald E Hoenig, Lori Webber, Stephen Sears, and Robert P Smith

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Chapter: Apitherapy-The use of honeybee products., Theodore Cherbuliez

Effect of a botanical acaricide on Ixodes scapularis (Acari: Ixodidae) and nontarget arthropods., Susan P Elias, Charles B Lubelczyk, Peter W Rand, Joseph K Staples, Theodore W St Amand, Constance S Stubbs, Eleanor H Lacombe, Leticia B Smith, and Robert P Smith

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Evolution of an innovative role: the clinical nurse leader., Lauri Wilson, Sonja Orff, Terilee Gerry, Bobbi R Shirley, Danielle Tabor, Kathryn Caiazzo, and Darlene Rouleau

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Health sciences libraries, Susan Bloomfield, Deborah Clark, Dina McKelvy, and Lucinda White

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Intra-amniotic delivery of amniotic-derived neural stem cells in a syngeneic model of spina bifida., Christopher Turner, Elliot C Pennington, Fabienne L Gray, Azra Ahmed, Yang D Teng, and Dario O Fauza

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Inverse propensity weighting to adjust for bias in fatal crash samples., David E Clark and Edward L Hannan

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Lower motor neuron findings after upper motor neuron injury: insights from postoperative supplementary motor area syndrome., Jeffrey E Florman, Hugues Duffau, and Anand I Rughani

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Management of microcarcinomas (papillary and medullary) of the thyroid., Leslie S Wu and Stacey A Milan

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Palmitate diet-induced loss of cardiac caveolin-3: a novel mechanism for lipid-induced contractile dysfunction., Catherine J Knowles, Martina Cebova, and Ilka M Pinz

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Spontaneous peripartum coronary artery dissection presentation and outcome., George L Higgins, Jennifer S Borofsky, Christine B Irish, Thomas S Cochran, and Tania D Strout

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Spry1 and Spry4 differentially regulate human aortic smooth muscle cell phenotype via Akt/FoxO/myocardin signaling., Xuehui Yang, Yan Gong, Yuefeng Tang, Hongfang Li, Qing He, Lindsey Gower, Lucy Liaw, and Robert E Friesel

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The case of the wandering kidney., David W Sobel and Brian M Jumper

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The logic of medical diagnosis., Donald E Stanley and Daniel G Campos

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The snail family gene snai3 is not essential for embryogenesis in mice., Cara K Bradley, Christine R Norton, Ying Chen, Xianghua Han, Carmen J Booth, Jeong Kyo Yoon, Luke T Krebs, and Thomas Gridley

Submissions from 2012

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Depression and cardiac surgery: underrecognized and undertreated., Anna Katharina Trede and Robert S Kramer

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Hazard regression models of early mortality in trauma centers., David E Clark, Jing Qian, Robert J Winchell, and Rebecca A Betensky

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International pediatric perfusion practice: 2011 survey results., Brian Harvey, Kenneth G Shann, David Fitzgerald, Brian Mejak, Donald S Likosky, Luc Puis, Robert A Baker, Robert C Groom, and American Society of ExtraCorporeal Technology's International Consortium for Evidence-Based Perfusion and Pediatric Perfusion Committee

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Mortality in rural locations after severe injuries from motor vehicle crashes., Lori L Travis, David E Clark, Amy E Haskins, and Joseph A Kilch

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Screening for spiritual distress in the oncology inpatient: a quality improvement pilot project between nurses and chaplains., Judith H. Blanchard, Douglas A Dunlap, and George Fitchett

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Think global and act local., Robert C Groom

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ERBB2 inhibition and heart failure., Gregory M Cote, Douglas B Sawyer, and Bruce A Chabner

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BMP9 regulates endoglin-dependent chemokine responses in endothelial cells., Kira Young, Barbara Conley, Diana Romero, Eric Tweedie, Christine O'Neill, Ilka Pinz, Louise Brogan, Volkhard Lindner, Lucy Liaw, and Calvin P H Vary

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Neuregulin in cardiovascular development and disease., Oghenerukevwe Odiete, Michael F Hill, and Douglas B Sawyer

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Evaluation of efficacy and dose response of different paclitaxel-coated balloon formulations in a novel swine model of iliofemoral in-stent restenosis., Krzysztof Milewski, Maxwell Eyram Afari, Armando Tellez, Michael S Aboodi, Jung-Sun Kim, Yanping Cheng, Gerard B Conditt, Jennifer C McGregor, Geng Hua Yi, Mark Stenoien, Dan Langanki, Christian G Krueger, Greg L Kaluza, and Juan F Granada

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Then and now: updating clinical nurse advancement programs., Amy L Owens and Jane Cleaves

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Understanding leptin-dependent regulation of skeletal homeostasis., Katherine J Motyl and Clifford J Rosen

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Use of computer alerts to prevent the inappropriate use of metformin in an inpatient setting., Ana P Rossi, Christopher A Wellins, Marizela Savic, and John T Devlin

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Compositions and Methods for Treating Inflammation and Fibrosis, Maine Medical Center, Peter C. Brooks, Leif Oxburg, and Jennifer M. Roth

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Bone as an endocrine organ., Anyonya R Guntur and Clifford J Rosen

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Dyspnea in a patient with Raynaud's phenomenon: the uncovering of interstitial lung disease., Anne Coates, Richard Meehan, and Carlos Milla

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Emergency neurological life support: airway, ventilation, and sedation., David B Seder, Richard R Riker, Andy Jagoda, Wade S Smith, and Scott D Weingart

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First trimester transabdominal chorionic villus sampling--does the needle matter?, Joseph R Wax, Angelina Cartin, Renée Chard, Molly Carpenter, and Michael G Pinette

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Medical student knowledge of global health problems: obstetric fistulas in developing countries., Caroline E Foust-Wright, S Abbas Shobeiri, Christine L Curry, Lieschen H Quiroz, and Mikio A Nihira

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Payer-provider collaboration in accountable care reduced use and improved quality in Maine Medicare Advantage plan., Thomas F Claffey, Joseph V Agostini, Elizabeth N Collet, Lonny Reisman, and Randall Krakauer

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The way life should be., Robert C Groom

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Variability in surgeons' perioperative practices may influence the incidence of low-output failure after coronary artery bypass grafting surgery., Donald S Likosky, Joshua B Goldberg, Anthony W DiScipio, Robert S Kramer, Robert C Groom, Bruce J Leavitt, Stephen D Surgenor, Yvon R Baribeau, David C Charlesworth, Robert E Helm, Carmine Frumiento, Gerald L Sardella, Robert A Clough, Todd A MacKenzie, David J Malenka, Elaine M Olmstead, Cathy S Ross, and Northern New England Cardiovascular Disease Study Group

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Treatment Of Cancer Using The Sodium Salt Of A Benzoic Acid Derivative, Peter C. Brooks, James Canary, and Leonard Liebes

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Does treatment of split-thickness skin grafts with negative-pressure wound therapy improve tissue markers of wound healing in a porcine experimental model?, Christopher Ward, David Ciraulo, Michael Coulter, Steven Desjardins, Lucy Liaw, and Sarah Peterson

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Psychotropic medications in children with autism spectrum disorders: a systematic review and synthesis for evidence-based practice., Matthew Siegel and Amy A Beaulieu