Incorporated in 1868, MMC is the state’s largest medical center, licensed for 700 beds and employing more than 9,600 people. MaineHealth Maine Medical Center’s unique role as both a community hospital and a referral center requires an unparalleled depth and breadth of services, including the state’s only allopathic medical school program, through a partnership with Tufts University School of Medicine, and a world-class biomedical research center, the MaineHealth Institute for Research.

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Submissions from 2014

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Women's Center Staff Perceptions of the Campus Climate on Sexual Violence., Tania Strout, Angela Frederick Amar, and Krystal Astwood

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Death associated protein kinase 2 is expressed in cortical interstitial cells of the mouse kidney., Justin A Guay, Don M Wojchowski, Jing Fang, and Leif Oxburgh

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Propagating the nephrology research workforce: a Kidney Research National Dialogue training commentary., Donald E Kohan, Mark G Parker, Susan L Furth, Billy G Hudson, Karen M Warburton, Krystyna E Rys-Sikora, and Tracy L Rankin

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Clinical impact of sacroplasty on patient mobility., Jennifer Talmadge, Kahsi Smith, Thomas Dykes, and Derek Mittleider

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Endovascular reconstruction of vertebral artery occlusion prior to basilar thrombectomy in a series of six patients presenting with acute symptomatic basilar thrombosis., Robert D Ecker, Crystiana A Tsujiura, Christopher B Baker, and Deborah Cushing

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Endovascular treatment of massive and submassive pulmonary embolism., Ethan Dobrow and Paul Kim

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Find your element., Robert C Groom

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Invited commentary., Robert S Kramer

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Kinomic exploration of temozolomide and radiation resistance in Glioblastoma multiforme xenolines., Joshua C Anderson, Christine W Duarte, Karim Welaya, Timothy D Rohrbach, Markus Bredel, Eddy S Yang, Nirmal V Choradia, Jaideep V Thottassery, George Yancey Gillespie, James A Bonner, and Christopher D Willey

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Mothers' Intentions to Breastfeed and Hospital Practices on Breastfeeding: A Longitudinal Study at 6 Months After Birth on Predictors of Breastfeeding in a Cohort of Mothers From a Large Northern New England Medical Center., Kara L. Kaikini and Kristiina Hykäs

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Navigating Prostate Cancer Screening in the Real World of Primary Care: The Mirage and the Quicksand., Paul Mathew, Hilal Hachem, and Paul Han

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Parasitism of mustelids by ixodid ticks (Acari: Ixodidae), Maine and New Hampshire, U.S.A., Charles Lubelczyk, Eleanor H Lacombe, Susan P Elias, Lorenza Beati, Peter W Rand, and Robert P Smith

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Perioperative management with antiplatelet and statin medication is associated with reduced mortality following vascular surgery., Randall R De Martino, Jens Eldrup-Jorgensen, Brian W Nolan, David H Stone, Julie Adams, Daniel J Bertges, Jack L Cronenwett, and Philip P Goodney

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Prenatal imaging and postnatal presentation, diagnosis and management of congenital lung malformations., James Wall and Anne Coates

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Randomized ICU trials do not demonstrate an association between interventions that reduce delirium duration and short-term mortality: a systematic review and meta-analysis., Nada S Al-Qadheeb, Ethan M Balk, Gilles L Fraser, Yoanna Skrobik, Richard R Riker, John P Kress, Shawn Whitehead, and John W Devlin

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The Development and Implementation of an Obstetrical Triage Tool to Prioritize Patients and Track Process Times by Risk Categories., Devdra Griffin and Kristiina Hyrkas

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Two- and three-dimensional prenatal sonographic diagnosis of Alagille syndrome., Joseph R Wax, Renée Chard, Michael G Pinette, and Angelina Cartin

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Bioenergetics during calvarial osteoblast differentiation reflect strain differences in bone mass., Anyonya R Guntur, Phuong T Le, Charles R Farber, and Clifford J Rosen

Comparison of a pediatric-specific and an institution-wide antibiogram, istina Smith, Jonathan Bourque, and Renee Fallon

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Effects of growth hormone administration for 6 months on bone turnover and bone marrow fat in obese premenopausal women., Miriam A Bredella, Anu V Gerweck, Lauren A Barber, Anne Breggia, Clifford J Rosen, Martin Torriani, and Karen K Miller

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Glycerol phenylbutyrate treatment in children with urea cycle disorders: pooled analysis of short and long-term ammonia control and outcomes., Susan A Berry, Uta Lichter-Konecki, George A Diaz, Shawn E McCandless, William Rhead, Wendy Smith, Cynthia Lemons, Sandesh C S Nagamani, Dion F Coakley, Masoud Mokhtarani, Bruce F Scharschmidt, and Brendan Lee

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Iron supplementation does not worsen respiratory health or alter the sputum microbiome in cystic fibrosis., Alex H Gifford, Diana M Alexandru, Zhigang Li, Dana B Dorman, Lisa A Moulton, Katherine E Price, Thomas H Hampton, Mitchell L Sogin, Jonathan B Zuckerman, H Worth Parker, Bruce A Stanton, and George A O'Toole

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Reconsidering against medical advice discharges., Daniel A Meyer

The changing face of America's children: A look at global child mental health., Julia C. Fritz

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The Initiative on Subspecialty Clinical Training and Certification (SCTC): Background and Recommendations., David K. Stevenson, Gail A. McGuinness, John D. Bancroft, Debra M. Boyer, Alan R. Cohen, Joseph T. Gilhooly, Mary Fran Zazinski, Eric S. Holmboe, M. Douglas Jones Jr, Marshall L. Land Jr, Sarah S. Long, Victoria F. Norwood, Daniel J. Schumacher, Theodore C. Sectish, Joseph W. St. Geme III, and Daniel C. West

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The results of a 2-year randomized trial of a worksite weight management intervention., Andrew E Williams, Victor J Stevens, Cheryl L Albright, Claudio R Nigg, Richard T Meenan, and Thomas M Vogt

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Transitory FGF treatment results in the long-lasting suppression of the proliferative response to repeated FGF stimulation., Ashleigh Poole, Nicholas Knowland, Emily Cooper, Rebecca Cole, Hongchuan Wang, Lucas Booth, Doreen Kacer, Francesca Tarantini, Robert Friesel, and Igor Prudovsky

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Trajectories of perceived benefits in living kidney donors: association with donor characteristics and recipient outcomes., James R Rodrigue, Matthew Paek, James Whiting, John Vella, Krista Garrison, Martha Pavlakis, and Didier A Mandelbrot

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Acceptability of telemedicine and other cancer genetic counseling models of service delivery in geographically remote settings., Eileen McDonald, Amanda Lamb, Barbara Grillo, Lee Lucas, and Susan Miesfeldt

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A comparison of usual care, a patient-centred education intervention and motivational interviewing to improve medication adherence and readmissions of adults in an acute-care setting., Kristiina Hyrkas and Marjorie Wiggins

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Bone morphogenetic protein signaling in nephron progenitor cells., Leif Oxburgh, Aaron C. Brown, Sree Deepthi Muthukrishnan, and Jennifer L. Fetting

Clinical Assessment of Dysexecutive Syndromes., John J. Campbell III and Annya Tisher

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Cryptic collagen IV promotes cell migration and adhesion in myeloid leukemia., Amanda J Favreau, Calvin P H Vary, Peter C Brooks, and Pradeep Sathyanarayana

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Perceived ambiguity, fatalism, and believing cancer is more prevalent than heart disease., William M P Klein, Rebecca A Ferrer, Kaitlin A Graff, Annette R Kaufman, and Paul K J Han

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Peripheral brain derived neurotrophic factor (BDNF) in bulimia nervosa: a systematic review., Kathryn Phillips, Kathleen Keane, and Barbara E Wolfe

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Physician shadowing by college students: what do patients think?, Robert G Bing-You, Victoria M Hayes, and Jennifer L Skolfield

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Delayed topical p38 MAPK inhibition attenuates full-thickness burn wound inflammatory signaling., Damien Carter, Adelaide Warsen, Katherine Mandell, Joseph Cuschieri, Ronald V Maier, and Saman Arbabi

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Editorial: Predicting surgical satisfaction using artificial neural networks., Anand I Rughani, Travis M Dumont, and Bruce I Tranmer

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Invited commentary., Robert S Kramer and Jeremiah R Brown

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miR-125a regulates cell cycle, proliferation, and apoptosis by targeting the ErbB pathway in acute myeloid leukemia., Melanie L Ufkin, Sarah Peterson, Xuehui Yang, Heather Driscoll, Christine Duarte, and Pradeep Sathyanarayana

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Neointimal patterns obtained by optical coherence tomography correlate with specific histological components and neointimal proliferation in a swine model of restenosis., Jung-Sun Kim, Maxwell E Afari, Jinyong Ha, Armando Tellez, Krzysztof Milewski, Gerard Conditt, Yanping Cheng, Geng Hua Yi, Greg L Kaluza, and Juan F Granada

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Neuregulin-1β induces embryonic stem cell cardiomyogenesis via ErbB3/ErbB2 receptors., Jijun Hao, Cristi L Galindo, Truc-Linh Tran, and Douglas B Sawyer

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Neuregulin as a heart failure therapy and mediator of reverse remodeling., Cristi L Galindo, Sergey Ryzhov, and Douglas B Sawyer

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Older women's willingness to discontinue Papanicolaou test screening., Ann Skelton, Celine Kuhn, Debra Rothenberg, and Alison Pope

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Use of transesophageal echocardiography to avoid a never event., Paul Lennon, Douglas Salvador, Reed Quinn, and Kathleen Black

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Analysis of intracorporeal compared with extracorporeal urinary diversion after robot-assisted radical cystectomy: results from the International Robotic Cystectomy Consortium., Kamran Ahmed, Shahid A Khan, Matthew H Hayn, Piyush K Agarwal, Ketan K Badani, M Derya Balbay, Erik P Castle, Prokar Dasgupta, Reza Ghavamian, Khurshid A Guru, Ashok K Hemal, Brent K Hollenbeck, Adam S Kibel, Mani Menon, Alex Mottrie, Kenneth Nepple, John G Pattaras, James O Peabody, Vassilis Poulakis, Raj S Pruthi, Joan Palou Redorta, Koon-Ho Rha, Lee Richstone, Matthias Saar, Douglas S Scherr, Stefan Siemer, Michael Stoeckle, Eric M Wallen, Alon Z Weizer, Peter Wiklund, Timothy Wilson, Michael Woods, and Muhammad Shamim Khan

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Developing, evaluating and validating a scoring rubric for written case reports., Peggy R Cyr, Kahsi A Smith, India L Broyles, and Christina T Holt

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Geriatric experience following cardiac arrest at six interventional cardiology centers in the United States 2006-2011: interplay of age, do-not-resuscitate order, and outcomes., David B Seder, Nainesh Patel, John McPherson, Paul McMullan, Karl B Kern, Barbara Unger, Sudip Nanda, Melkon Hacobian, Michael B Kelley, Niklas Nielsen, John Dziodzio, and Michael Mooney

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Is there a place for medical students as teachers in the education of junior residents?, Keith Wirth, Bethany Malone, Kaylene Barrera, Warren D Widmann, Christopher Turner, and Aliu Sanni

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Modifiable risk factors associated with tuberculosis disease in children in Pune, India., J Jubulis, A Kinikar, M Ithape, M Khandave, S Dixit, S Hotalkar, V Kulkarni, V Mave, N Gupte, A Kagal, S Jain, R Bharadwaj, and A Gupta

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Phenylalanine hydroxylase deficiency: diagnosis and management guideline., Jerry Vockley, Hans C Andersson, Kevin M Antshel, Nancy E Braverman, Barbara K Burton, Dianne M Frazier, John Mitchell, Wendy E Smith, Barry H Thompson, and Susan A Berry

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Regulation of the follistatin gene by RSPO-LGR4 signaling via activation of the WNT/β-catenin pathway in skeletal myogenesis., Xiang Hua Han, Yong-Ri Jin, Leonard Tan, Tatiana Kosciuk, Jin-Seon Lee, and Jeong Kyo Yoon

Resveratrol: Highlights of Relatively Recent Interest in an Old Chemical., Ted Wissink and Matt Stevens

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Thirty U.S. Poison Center reports later: greater demand, more difficult problems., K E Simone

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Methods For Treating Metabolic Syndrome With Cthrc1 Polypeptide, Volkhard Lindner and Maine Medical Center

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Pediatric refugees in Rhode Island: increases in BMI percentile, overweight, and obesity following resettlement., Jessica H Heney, Camia C Dimock, Jennifer F Friedman, and Carol Lewis

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Driving policy after seizures and unexplained syncope: a practice guide for RI physicians., Maxwell E Afari, Andrew S Blum, Stephen T Mernoff, and Brian R Ott

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Adrenal insufficiency in a woman secondary to standard-dose inhaled fluticasone propionate therapy., Casey M Hay and Daniel I Spratt

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Advances in therapy for pediatric sarcomas., Aaron Weiss, Jonathan Gill, John Goldberg, Joanne Lagmay, Holly Spraker-Perlman, Rajkumar Venkatramani, and Damon Reed

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A matter of balance: older adults taking control of falls by building confidence., Margaret Haynes, Patricia League, and Gloria Neault

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An argument for comprehensiveness as the "special sauce" in a recipe for the patient-centered medical home., Christina Holt

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Blood levels of S-100 calcium-binding protein B, high-sensitivity C-reactive protein, and interleukin-6 for changes in depressive symptom severity after coronary artery bypass grafting: prospective cohort nested within a randomized, controlled trial., Daniel M Pearlman, Jeremiah R Brown, Todd A MacKenzie, Felix Hernandez, and Souhel Najjar

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Breast cancer knowledge, beliefs, and screening practices among women seeking care at district hospitals in Dar es Salaam, Tanzania., Emma Perry Morse, Bertha Maegga, Gertrud Joseph, and Susan Miesfeldt

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Chapter: Practice in a rural setting., Robert J. Ferguson, Amber Ferguson, Jeff Matranga, and Sandra Sigmon

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Chapter: Systems development of behavioral health in primary care., Julie Schirmer and Jeffery F. Markuns

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Common features of microRNA target prediction tools., Sarah M Peterson, Jeffrey A Thompson, Melanie L Ufkin, Pradeep Sathyanarayana, Lucy Liaw, and Clare Bates Congdon

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Communication of suicidality via social media., Erin L. Belfort

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Deficiency of Sef is associated with increased postnatal cortical bone mass by regulating Runx2 activity., Qing He, Xuehui Yang, Yan Gong, Dmitry Kovalenko, Ernesto Canalis, Clifford J Rosen, and Robert E Friesel

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Detection of eastern equine encephalitis virus antibodies in moose (Alces americana), Maine, 2010., Charles Lubelczyk, Susan P Elias, Lee Kantar, Jennifer Albert, Stephen Hansen, Kali Saxton-Shaw, Katharine MacMillan, Leticia B Smith, Rebecca Eisen, Bethany Swope, Robert Pease Smith, and John-Paul Mutebi

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Development and evaluation of a risk communication curriculum for medical students., Paul K J Han, Katherine Joekes, Glyn Elwyn, Kathleen M Mazor, Richard Thomson, Philip Sedgwick, Judith Ibison, and John B Wong

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Early cardiac catheterization is associated with improved survival in comatose survivors of cardiac arrest without STEMI., Ryan D Hollenbeck, John A McPherson, Michael R Mooney, Barbara T Unger, Nainesh C Patel, Paul W McMullan, Chiu-Hsieh Hsu, David B Seder, and Karl B Kern

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Effect of a dedicated acute care operating room on hospital efficiency., Cecilia Trydestam, Steven Prato, Brad Cushing, and James Whiting

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Elevated plasma levels of the pituitary hormone Cthrc1 in individuals with red hair but not in patients with solid tumors., Christine W Duarte, J Patrizia Stohn, Qiaozeng Wang, Ivette F Emery, Andrew Prueser, and Volkhard Lindner

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Evidence-based leadership council - a national collaborative., Margaret Haynes, Susan Hughes, Kate Lorig, June Simmons, Susan J Snyder, Lesley Steinman, Nancy Wilson, Roseanne DiStefano, Jennifer Raymond, Stephanie FallCreek, Martha B Pelaez, and Don Smith

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Factors associated with different patterns of nonadherence to HIV care in Dar es Salaam, Tanzania., Gabriela Poles, Michelle Li, Hellen Siril, Aisa Mhalu, Claudia Hawkins, Sylvia Kaaya, Eric Aris, Guerino Chalamilla, and Lisa R Hirschhorn

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FOXD1 promotes nephron progenitor differentiation by repressing decorin in the embryonic kidney., Jennifer L Fetting, Justin A Guay, Michele J Karolak, Renato V Iozzo, Derek C Adams, David E Maridas, Aaron C Brown, and Leif Oxburgh

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Home diuretic protocol for heart failure: partnering with home health to improve outcomes and reduce readmissions., Richard P Veilleux, Joseph N Wight, Ann Cannon, Moira Whalen, and David Bachman

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Impact of perioperative acute kidney injury as a severity index for thirty-day readmission after cardiac surgery., Jeremiah R Brown, Chirag R Parikh, Cathy S Ross, Robert S Kramer, Patrick C Magnus, Kristine Chaisson, Richard A Boss, Robert E Helm, Susan R Horton, Patricia Hofmaster, Helen Desaulniers, Pamela Blajda, Benjamin M Westbrook, Dennis Duquette, Kelly LeBlond, Reed D Quinn, Cheryl Jones, Anthony W DiScipio, and David J Malenka

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Improved survival outcomes in cancer patients with hereditary hemorrhagic telangiectasia., Christine W Duarte, Kimberly Murray, F Lee Lucas, Kathleen Fairfield, Heather Miller, Peter Brooks, and Calvin P H Vary

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Next generation sequencing reveals skewing of the T and B cell receptor repertoires in patients with Wiskott-Aldrich syndrome., Amy E O'Connell, Stefano Volpi, Kerry Dobbs, Claudia Fiorini, Erdyni Tsitsikov, Helen de Boer, Isil B Barlan, Jenny M Despotovic, Francisco J Espinosa-Rosales, I Celine Hanson, Maria G Kanariou, Roxana Martínez-Beckerat, Alvaro Mayorga-Sirera, Carmen Mejia-Carvajal, Nesrine Radwan, Aaron R Weiss, Sung-Yun Pai, Yu Nee Lee, and Luigi D Notarangelo

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Overview of genetic tools and techniques to study Notch signaling in mice., Thomas Gridley and Andrew K Groves

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Partnership, Maine Medical Center

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Psychiatric hospital treatment of children with autism and serious behavioral disturbance., Matthew Siegel and Robin L Gabriels

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Relationship between regional spending on vascular care and amputation rate., Philip P Goodney, Lori L Travis, Benjamin S Brooke, Randall R DeMartino, David C Goodman, Elliott S Fisher, and John D Birkmeyer

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The epidemiology and pathogenesis of osteoporosis., Clifford J. Rosen

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The Snail transcription factor regulates the numbers of neural precursor cells and newborn neurons throughout mammalian life., Mark A Zander, Gonzalo I Cancino, Thomas Gridley, David R Kaplan, and Freda D Miller

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Total knee arthroplasty designed to accommodate the presence or absence of the posterior cruciate ligament., Melinda K Harman, Stephanie J Bonin, Chris J Leslie, Scott A Banks, and W Andrew Hodge

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Transfer of intracellular HIV Nef to endothelium causes endothelial dysfunction., Ting Wang, Linden A Green, Samir K Gupta, Chul Kim, Liang Wang, Sharilyn Almodovar, Sonia C Flores, Igor A Prudovsky, Paul Jolicoeur, Ziyue Liu, and Matthias Clauss

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Unfreezing the Flexnerian Model: introducing longitudinal integrated clerkships in rural communities., Robert G Bing-You, Robert L Trowbridge, Catherine Kruithoff, and John L Daggett

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Use of osmium tetroxide staining with microcomputerized tomography to visualize and quantify bone marrow adipose tissue in vivo., Erica L Scheller, Nancy Troiano, Joshua N Vanhoutan, Mary A Bouxsein, Jackie A Fretz, Yougen Xi, Tracy Nelson, Griffin Katz, Ryan Berry, Christopher D Church, Matthew S Rodeheffer, Ormond A Macdougald, Clifford J Rosen, Mark C Horowitz, and Casey R. Doucette

Submissions from 2013

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Impairment of subendocardial perfusion reserve and oxidative metabolism in nonischemic dilated cardiomyopathy., Susan P Bell, Douglas W Adkisson, Henry Ooi, Douglas B Sawyer, Mark A Lawson, and Marvin W Kronenberg

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Radical, passionate, and curious., Robert C Groom

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Validity and reliability of the critical care pain observation tool: a replication study., Kathleen Marie Keane

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Vitamin D and calcium: what do we need to know?, Vincent Zhang, Xuezhi Jiang, Yousaf Z Farukhi, Clifford J Rosen, and Peter F Schnatz

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Absence of a major role for the snai1 and snai3 genes in regulating skeletal muscle regeneration in mice., Christine R Norton, Ying Chen, Xiang Hua Han, Cara K Bradley, Luke T Krebs, Jeong Kyo Yoon, and Thomas Gridley

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Know Thyself: A Knowledge Repository in the Hospital Setting, Dina McKelvy

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Contemporary issues in nursing: patient safety, decision-making and social support in challenging economic times., Lynn Macken and Kristiina Hyrkas

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Estimating the effect of emergency care on early survival after traffic crashes., David E Clark, Robert J Winchell, and Rebecca A Betensky

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Risk modifiers for concussion and prolonged recovery., Kristen A Scopaz and John R Hatzenbuehler

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Testing the reliability of the Fall Risk Screening Tool in an elderly ambulatory population., Susan J Fielding, Michael McKay, and Kristiina Hyrkas