Incorporated in 1868, MMC is the state’s largest medical center, licensed for 700 beds and employing more than 9,600 people. Maine Medical Center’s unique role as both a community hospital and a referral center requires an unparalleled depth and breadth of services, including the state’s only allopathic medical school program, through a partnership with Tufts University School of Medicine, and a world-class biomedical research center, the MaineHealth Institute for Research.

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Submissions from 2019

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Post Lumbar-Puncture Headache Experience in a Community Hospital (PEACH) Study, Melissa Kessel, Caroline Knight, and Robert Stein

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Potential of vascular endothelial growth factor as a biomarker of coronary artery disease in subjects undergoing CABG surgery, Teaka Jackson, Sarah Peterson, Amanda Favreau-Lessard, Joanne Burgess, Susan Bosworth-Farrell, Robert S. Kramer, Douglas B. Sawyer, Sergey Ryzhov, and Michael P. Robich

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Predictors for Discharge After Robotic Hysterectomy – A Retrospective Analysis, Heidi Fox and Kristiina Hyrkas

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Primary cilia of the cardiac neural crest orchestrate critical aspects of ventricular myocardial maturation and postnatal cardiac function, Lindsey Fitzsimons

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Prions to Pathways: Safeguarding Against Creutzfeldt-Jakob Disease in the Operating Room, Jessica Mary Adams Atkinson and Sonja Carol Orff

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Problematic Internet Use and Associated High-Risk Behavior in an Adolescent Clinical Sample: Results from a Survey of Psychiatrically Hospitalized Youth., Meredith Gansner, Erin Belfort, Benjamin Cook, Caroline Leahy, Andrea Colon-Perez, Danielle Mirda, and Nicholas Carson

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Reducing Catheter Associated Urinary Tract Infections (CAUTI) by Decreasing Use of Indwelling Catheters, Joanne Chapman, Brenda Clark, Brian Jumper, and Carrie Strick

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Reducing Length of Stay for Mental Health Patients, Faye Collins and Nancijean Goudey

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Scaffolding kidney organoids on silk., Ashwani Kumar Gupta, Jeannine M Coburn, Jessica Davis-Knowlton, Erica Kimmerling, David L Kaplan, and Leif Oxburgh

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Seerratus Anterior Plane Block (SAPB) Improves Paine Control in Rib Fractures, Randy Kring, Peter Croft, David Mackenzie, Christina Wilson, Joseph Rappold, and Tania D. Strout

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Social influence and moment-to-moment changes in young adults’ mood and psychotic symptoms, K Powers, K A. Johnson, M Graham, A Cloutier, K Stewart, S Lynch, D Robbins, R Mesholm-Gately, and K A. Woodberry

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Ten-year Outcomes of Cervical Disc Replacement With the BRYAN Cervical Disc: Results From a Prospective, Randomized, Controlled Clinical Trial., William F Lavelle, K Daniel Riew, Allan D Levi, and Jeffrey E Florman

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The association between feeding protocol compliance and weight gain following high-risk neonatal cardiac surgery., Jamie M Furlong-Dillard, Benjamin J Miller, Kathy A Sward, Alaina I Neary, Trudy L Hardin-Reynolds, Grace Jeffers, Bonnie A Clay, Dongngan T Truong, Thomas Miller, Courtney E Jones, Linda M Lambert, and David K Bailly

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The effect of beta blocker use on bone outcomes using the Framingham Osteoporosis Study, Christine Lary

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The Functional Food Diet: A Pilot Study, Caroline Knight and Ralph Hamill

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The Innovations Cohort, Jennifer Monti

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The relationship between uncertainty tolerance and oncologists’ perceptions of large-panel genomic tumor testing, Eric Anderson, Alexandra Hinton, Christine Lary, Kimberly Murray, Leo Waterson, Paul Han, and Maine Cancer Genomics Initiative

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Using Social Media to Broaden Understanding of the Barriers and Facilitators to Exercise in Adults With Type 1 Diabetes., Tamara K Oser, Kaitlin A Minnehan, Glenna Wong, Jessica Parascando, Erin McGinley, Julie Radico, and Sean M Oser

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Validity of neonatal POC glucose testing, Matthew Turnquist, Amy Haskins, and Christina Holt

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Wellness in Teaching: a dynamic educational intervention to improve faculty performance, Sue Rose, Vicki Hayes, Christine Hein, Amy Sedgwick, Bryan Lamoreau, and Wendy Craig

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What’s Happening to our Patients in their Final Year of Life?, Teresa Letellier, Amy Haskins, and Christina Holt

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Where we were, where we are, and where are we going? The state of research at MaineHealth, Clifford J. Rosen

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Young Man With Hip Injury., Matthew J Spanier and David C Mackenzie

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Microvascular and systemic impact of resuscitation with pegylated carboxyhemoglobin-based oxygen carrier or hetastarch in a rat model of transient hemorrhagic shock., William H Nugent, Forest R Sheppard, Michael A Dubick, Ramon F Cestero, Daniel N Darlington, Ronald Jubin, Abe Abuchowski, and Bjorn K Song

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Patients' responses to incidentally discovered silent brain infarcts - a qualitative study., Lester Y Leung, Paul K J Han, Christine Lundquist, Gene Weinstein, David E Thaler, and David M Kent

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AO Patient Outcomes Center: Design, Implementation, and Evaluation of a Software Application for the Collection of Patient-Reported Outcome Measures in Orthopedic Outpatient Clinics., Nan E Rothrock, Michael Bass, Andrea Blumenthal, Richard C Gershon, Beate Hanson, Alexander Joeris, Aaron Kaat, Suzanne Morrison, Robert V O'Toole, Shalini Patel, Michael Stover, Michael J Weaver, Raymond White, Maria Varela Diaz, and Mark S Vrahas

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Letter to the Editor., James R Rodrigue, Aaron Fleishman, Claire M Sokas, Jesse D Schold, Paul Morrissey, James Whiting, John Vella, Liise K Kayler, Daniel Katz, Jody Jones, Bruce Kaplan, Martha Pavlakis, and Didier A Mandelbrot

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Association between the food and physical activity environment, obesity, and cardiovascular health across Maine counties., Allison C Briggs, Adam W Black, F Lee Lucas, Andrea E Siewers, and Kathleen M Fairfield

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Pharmacist-Managed Inpatient Dofetilide Initiation Program: Description and Adherence Rate Post-Root Cause Analysis., Elena You Jung Ko, Charles M Carpenter, David J Gagnon, and Anne M Andrle

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A Comprehensive Update on Treatment of Dementia., Annya Tisher and Arash Salardini

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Are children severely affected by autism spectrum disorder underrepresented in treatment studies? An analysis of the literature, Amy Stedman, Matthew Siegel, Briana Taylor, Michael Erard, and Christine Peura

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Associations of protein intake in early childhood with body composition, height, and insulin-like growth factor I in mid-childhood and early adolescence., Karen M. Switkowski, Paul F. Jacques, Aviva Must, Abby Fleisch, and Emily Oken

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Body composition and bone mineral density in childhood., Lisa B Rokoff, Sheryl L Rifas-Shiman, Karen M Switkowski, Jessica G Young, Clifford J Rosen, Emily Oken, and Abby F Fleisch

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Editorial Comment., Jesse Sammon

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Management of Post-transplant Hyperparathyroidism and Bone Disease., Rowena Delos Santos, Daniel Coyne, Ana Rossi, and Thin Thin Maw

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Pulmonary hypertension subjects exhibit right ventricular transient exertional dilation during supine exercise stress echocardiography., Rama El-Yafawi, David Rancourt, Melkon Hacobian, Dennis Atherton, Mylan C Cohen, and Joel A Wirth

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Resistance to visceral obesity is associated with increased locomotion in mice expressing an endothelial cell-specific fibroblast growth factor 1 transgene., Tyler Keeley, Aleksandr Kirov, Woon Yuen Koh, Victoria Demambro, Ivy Bergquist, Jessica Cotter, Peter Caradonna, Matthew E Siviski, Bradley Best, Terry Henderson, Clifford J Rosen, Lucy Liaw, Igor Prudovsky, and Deena J Small

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Senescent and apoptotic osteocytes and aging: Exercise to the rescue?, Vanessa D Sherk and Clifford J Rosen

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Tolerating uncertainty about conceptual models of uncertainty in health care., Paul K.J. Han and Benjamin Djulbegovic

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Tranexamic acid suppresses the release of mitochondrial DAMPs and reduces lung inflammation in a murine burn model., Damien Wilson Carter, Igor Prudovsky, Doreen Kacer, Tee Soul, Chloe Kumpel, Kathleen Pyburn, Monica Palmeri, Robert Kramer, and Joseph Rappold

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Vertical transmission rates of Borrelia miyamotoi in Ixodes scapularis collected from white-tailed deer., Seungeun Han, Charles Lubelczyk, Graham J Hickling, Alexia A Belperron, Linda K Bockenstedt, and Jean I Tsao

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Intestinal clock system regulates skeletal homeostasis., Masanobu Kawai, Saori Kinoshita, Miwa Yamazaki, Keiko Yamamoto, Clifford J Rosen, Shigeki Shimba, Keiichi Ozono, and Toshimi Michigami

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Differentiation Capacity of Human Aortic Perivascular Adipose Progenitor Cells., S Spencer Scott, Xuehui Yang, Michael Robich, Lucy Liaw, and Joshua M Boucher

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Abdominal Pain After a Football Game., Heidi M Goddard, Casey Z MacVane, and Tania D Strout

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Achievement of Guideline-Recommended Weight Loss Among Patients With Ischemic Stroke and Obesity., Jennifer L Dearborn, Catherine M Viscoli, Lawrence H Young, Mark J Gorman, Karen L Furie, and Walter N Kernan

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A randomized phase II study of cabozantinib versus weekly paclitaxel in the treatment of persistent or recurrent epithelial ovarian, fallopian tube or primary peritoneal cancer: An NRG Oncology/Gynecologic Oncology Group study., Ursula A Matulonis, Michael W Sill, Vicky Makker, David G Mutch, Jay W Carlson, Christopher J Darus, Robert S Mannel, David P Bender, Erin K Crane, and Carol Aghajanian

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Assessing feasibility of resources at health facilities in Uganda to diagnose pregnancy and neonatal outcomes., James H Stark, Eve Wool, Lena Tran, Elizabeth Robinson, Meaghan Chemelski, Daniel Weibel, Wan-Ting Huang, Sonali Kochhar, Janet R Hardy, Steven Bailey, Edward Galiwango, and Dan Kajungu

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A systematic review of micronutrient deficiencies in pediatric inflammatory bowel disease., Julia Fritz, Cassandra Walia, Abdul Elkadri, Rebecca Pipkorn, Rachel K. Dunn, Rita Sieracki, Praveen S. Goday, and Jose Mariano Cabrera

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Characterization of smooth muscle cells from human atherosclerotic lesions and their responses to Notch signaling., Jessica Davis-Knowlton, Jacqueline E Turner, Anna Turner, Sydney Damian-Loring, Nicholas Hagler, Terry Henderson, Ivette F Emery, Kyle Bond, Christine W Duarte, Calvin P H Vary, Jens Eldrup-Jorgensen, and Lucy Liaw

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Do we need continuous electroencephalography after cardiac arrest?, Teresa May, Richard R. Riker, and David Seder

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Inpatient Psychiatric Treatment of Serious Behavioral Problems in Children with Autism Spectrum Disorder (ASD): Specialized Versus General Inpatient Units., Briana J. Taylor, Kevin B. Sanders, Marie Kyle, Kahsi A. Pedersen, Jeremy Veenstra-Vanderweele, and Matthew Siegel

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Interactions with Muscle Cells Boost Fusion, Stemness, and Drug Resistance of Prostate Cancer Cells., Berna Uygur, Evgenia Leikina, Kamran Melikov, Rafael Villasmil, Santosh K Verma, Calvin P H Vary, and Leonid V Chernomordik

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Multiple Myeloma and Fatty Acid Metabolism., Majdi Masarwi, Abigail DeSchiffart, Justin Ham, and Michaela R Reagan

Point-of-Care versus Central Laboratory Glucose Testing in Postoperative Cardiac Surgery Patients., Robert S. Kramer, Monica Palmeri, Michael Robich, Frances L. Lucas, Robert Groom, Timothy Hayes, Marie Janoushek, Joseph F. Rappold, William L. Swartz, and Reed Quinn

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Prognostic value of a modified surprise question designed for use in the emergency department setting., Samir A Haydar, Tania D Strout, Alicia G Bond, and Paul Kj Han

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Why Residents Quit: National Rates of and Reasons for Attrition Among Emergency Medicine Physicians in Training., Dave W. Lu, Nicholas D. Hartman, Jeffrey Druck, Jennifer Mitzman, and Tania D. Strout

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An Analysis of Psychoactive Medications Initiated in the ICU but Continued Beyond Discharge: A Pilot Study of Stewardship., Nicole Lynn Kovacic, David J Gagnon, Richard R Riker, Sijin Wen, and Gilles L Fraser

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Cholecystectomy reduced major complications vs catheter drainage in high-risk patients with acute cholecystitis., Joseph F. Rappold

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Aligning Strategic Interests in an Academic Medical Center: A Framework for Evaluating GME Expansion Requests, Kalli Varaklis, Mark G. Parker, Jordan S. Peck, and Robert G. Bing-You

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A simple matrix to predict treatment success and long-term survival among patients undergoing pancreatectomy., Timothy L Fitzgerald, Lucas Hunter, Catalina Mosquera, Charulata Jindal, Tithi Biswas, Emmanuel Zervos, and Jimmy T Efird

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Clinical Disorders of the Kidney., James C Chan

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Educating Caregivers To Provide Safe Care., Marjorie S. Wiggins, Peter Bates, and James Benneyan

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Empyema commission of 1918-Impact on acute care surgery 100 years later., Jamie Tung, Damien Carter, and Joseph Rappold

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Evaluation and Management of Neck and Back Pain., John W Martel and Samuel B Potter

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Impact of Contralateral Symmetry Procedures on Long-Term Patient-Reported Outcomes following Unilateral Prosthetic Breast Reconstruction., Shantanu N Razdan, Hina Panchal, Claudia R Albornoz, Andrea L Pusic, Colleen C McCarthy, Peter G Cordeiro, Joseph J Disa, Babak J Mehrara, and Evan Matros

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Impact of Initial Shunt Type on Echocardiographic Indices in Children After Single Right Ventricle Palliations., Peter C Frommelt, Chenwei Hu, Felicia Trachtenberg, Jeanne Marie Baffa, Richard J Boruta, Shahryar Chowdhury, James F Cnota, Andreea Dragulescu, Jami C Levine, Jimmy Lu, Laura Mercer-Rosa, Thomas Miller, Amee Shah, Timothy C Slesnick, Gary Stapleton, Jessica Stelter, Pierre Wong, and Jane W Newburger

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Intensity of Glycemic Control Affects Long-Term Survival After Coronary Artery Bypass Graft Surgery., Michael P Robich, Alexander Iribarne, Bruce J Leavitt, David J Malenka, Reed D Quinn, Elaine M Olmstead, Cathy S Ross, Douglas B Sawyer, John D Klemperer, Robert A Clough, Robert S Kramer, Yvon R Baribeau, Gerald L Sardella, Anthony W DiScipio, and Northern New England Cardiovascular Disease Study Group

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Introduction to the supplement on cellular therapies in trauma and critical care medicine., Shibani Pati, Martin Schreiber, and Joseph Rappold

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Low-dose compared to manufacturer-recommended dose four-factor prothrombin complex concentrate for acute warfarin reversal., Wesley Zemrak, Francis Manuel, Kathryn E Smith, Stephen Rolfe, Timothy Hayes, Robert L Trowbridge, Brian Carlone, and David Seder

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Low-Dose Prothrombin Complex Concentrate in Patients with Left Ventricular Assist Devices., Caitlin S Brown, Wesley R Zemrak, Kaitlin J Dyer, and Stephen Rolfe

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Palliative Care Clinician Overestimation of Survival in Advanced Cancer: Disparities and Association With End-of-Life Care., Robert Gramling, Elizabeth Gajary-Coots, Jenica Cimino, Kevin Fiscella, Ronald Epstein, Susan Ladwig, Wendy Anderson, Stewart C Alexander, Paul K Han, David Gramling, and Sally A Norton

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Patients with end-stage renal disease have poor outcomes after endovascular abdominal aortic aneurysm repair., Sevan Komshian, Alik Farber, Virendra I Patel, Philip P Goodney, Marc L Schermerhorn, Elizabeth A Blazick, Douglas W Jones, Denis Rybin, Gheorghe Doros, and Jeffrey J Siracuse

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Posttransplant Malignancy., Ana P Rossi and Christina L Klein

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Progenitor recruitment and adipogenic lipolysis contribute to the anabolic actions of parathyroid hormone on the skeleton., David E Maridas, Elizabeth Rendina-Ruedy, Ron C Helderman, Victoria E DeMambro, Daniel Brooks, Anyonya R Guntur, Beate Lanske, Mary L Bouxsein, and Clifford J. Rosen

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Providing mental health care in teh context of online mental health notes: advice from patients and mental health clinicians., Maura Pisciotta, Lauren Denneson, Holly B. Williams, Susan Woods, Anais Tuepker, and Steven K. Dobscha

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Recovery of Kidney Dysfunction After Transcatheter Aortic Valve Implantation (from the Northern New England Cardiovascular Disease Study Group)., Amir Azarbal, David J Malenka, Yi-Ling Huang, Cathy S Ross, Richard J Solomon, James T DeVries, James M Flynn, David Butzel, Matthew McKay, and Harold L Dauerman

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Sedative and Analgesic Drug Sequestration After a Single Bolus Injection in an Ex Vivo Extracorporeal Membrane Oxygenation Infant Circuit., Viviane G Nasr, Jonathan Meserve, Luis M Pereira, David Faraoni, Steve Brediger, Susan Goobie, Ravi Thiagarajan, and James A DiNardo

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Symptomatic Adjacent Level Disease Requiring Surgery: Analysis of 10-Year Results From a Prospective, Randomized, Clinical Trial Comparing Cervical Disc Arthroplasty to Anterior Cervical Fusion., George M Ghobrial, William F Lavelle, Jeffrey E Florman, K Daniel Riew, and Allan D Levi

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Why the disconnect? Problems with a clamp style catheter connector., Ryan Mountjoy, Craig Curry, Olga Diomede, and Paula McKinley

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Wilderness Neurology., Sarah M Schlein, Paul G Marcolini, and Evie G Marcolini

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Functional analysis of monocarboxylate transporter 8 mutations in Japanese Allan-Herndon-Dudley syndrome patients., Mohammad Saiful Islam, Noriyuki Namba, Yasuhisa Ohata, Makoto Fujiwara, Chiho Nakano, Shinji Takeyari, Kei Miyata, Yukako Nakano, Kenichi Yamamoto, Hirofumi Nakayama, Taichi Kitaoka, Takuo Kubota, and Keiichi Ozono

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Correction: Mixed lineage kinase 3 promotes breast tumorigenesis via phosphorylation and activation of p21-activated kinase 1, Subhasis Das, Rakesh Sathish Nair, Rajakishore Mishra, Gautam Sondarva, Navin Viswakarma, Hazem Abdelkarim, Vadim Gaponenko, Pradeep Sathyanarayana, Basabi Rana, and Ajay Rana

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Pathologic Complete Response (pCR) and Survival of Women with Inflammatory Breast Cancer (IBC): An Analysis Based on Biologic Subtypes and Demographic Characteristics., Tithi Biswas, Charulata Jindal, Timothy L Fitzgerald, and Jimmy T Efird

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VITAL Signs for Dietary Supplementation to Prevent Cancer and Heart Disease., John F Keaney and Clifford J Rosen

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A Public Health Perspective on Screening for Psychosis Within General Practice Clinics., Leda Kennedy, Kelsey A Johnson, Joyce Cheng, and Kristen A Woodberry

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Association of hypokalemia with an increased risk for medically treated arrhythmias., Colin T Phillips, Junmei Wang, Leo Anthony Celi, Zhengbo Zhang, and Mengling Feng

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Bone Marrow Adiposity- Special Edition., Beata Lecka-Czernik and Clifford J Rosen

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Commentary: 2018 Stroke Guidelines., Andrew D. Perron and John H. Burton

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Development of a 3D bone marrow adipose tissue model., Heather Fairfield, Carolyne Falank, Mariah Farrell, Calvin Vary, Joshua M Boucher, Heather Driscoll, Lucy Liaw, Clifford J Rosen, and Michaela R Reagan

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Disability-Adjusted Life-Years Due to Stroke in Kenya., Lydia Kaduka, Erastus Muniu, Jane Mbui, Chrispine Oduor Owuor, Robai Gakunga, Judith Kwasa, Sylvanus Wabwire, Nathan Okerosi, Anne Korir, and Scot C Remick

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Dyspnea: diagnosis of hyperthyroidism by cardiac catheterization., Jay Shah, Louis Coyle, Joel Wirth, and Thomas Ryan

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Educational preferences among residents in the ICU, Jason Block and Patricia Lerwick

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Effective Advocacy for Patients and Communities., Cynthia Haq, Melissa Stiles, Debra Rothenberg, and Heather Lukolyo

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Evaluation of portable colposcopy and human papillomavirus testing for screening of cervical cancer in rural China, Haley Newman, Jilin Hu, Xiao Li, Jing He, Leslie Bradford MD, Songmei Shan, Xiaomei Wu, Bin Zhu, Wenyang Yang, Bingqin Fu, Baosheng Zhu, and Guangping Gao

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Evaluations of serum potassium during pentobarbital administration in critically ill patients., Kathryn Smith, William Crall, David Gagnon, Elizabeth Glisic, David Seder, and Richard Riker

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Evaluation the transition from dexmedetomidine to enteral clonidine in adult ICU patients., Nicholas Pozzessere, Richard Riker, Gilles Fraser, David Gagnon, Jonathan Rud, Allison Fluke, and Elizabeth Glisic

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Fibrinolysis shutdown in trauma: historical review and clinical implications., Hunter B Moore, Ernest E Moore, Matthew D Neal, Forest R Sheppard, Lucy Z Kornblith, Dominik F Draxler, Mark Walsh, Robert L Medcalf, Mitch J Cohen, Bryan A Cotton, Scott G Thomas, Christine M Leeper, Barbara A Gaines, and Angela Sauaia

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Findings of a Statewide Environmental Lead Inspection Program Targeting Homes of Children With Blood Lead Levels as Low as 5 µg/dL., Rachel Cluett, Abby Fleisch, Kathy Decker, Eric Frohmberg, and Andrew E. Smith

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Increasing medical student interest in nephrology., Stephen M Sozio, Kurtis A Pivert, Hitesh H Shah, Harini A Chakkera, Abdo R Asmar, Manu R Varma, Benjamin D Morrow, Ankit B Patel, Katlyn Leight, and Mark G Parker

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Increasing Referrals to a Community Paramedicine Fall Prevention Program Through Implementation of a Daily Management System., Julianne B. Ontengco