Incorporated in 1868, MMC is the state’s largest medical center, licensed for 700 beds and employing more than 9,600 people. MaineHealth Maine Medical Center’s unique role as both a community hospital and a referral center requires an unparalleled depth and breadth of services, including the state’s only allopathic medical school program, through a partnership with Tufts University School of Medicine, and a world-class biomedical research center, the MaineHealth Institute for Research.

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Submissions from 2019

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Tracheostomy Practices in Neurocritical Care., David B Seder

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Use of Donor Milk to Improve Exclusive Breast-Milk Feeding Rates for Newborns on the Mother–Baby Unit...2019 AWHONN Convention, June 8-12, 2019, Atlanta, Georgia, Sharon Craig Economides and Jennifer Johnson

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Woman with cirrhosis and shortness of breath., Christopher Allison and David Mackenzie

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Endothelial Cells Regulate Physiological Cardiomyocyte Growth via VEGFR2-Mediated Paracrine Signaling., Riikka Kivelä, Karthik Amudhala Hemanthakumar, Katri Vaparanta, Marius Robciuc, Yasuhiro Izumiya, Hiroyasu Kidoya, Nobuyuki Takakura, Xuyang Peng, Douglas B Sawyer, Klaus Elenius, Kenneth Walsh, and Kari Alitalo

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TAVR in Low-Risk Patients: 1-Year Results From the LRT Trial., Ron Waksman, Paul J Corso, Rebecca Torguson, Paul Gordon, Afshin Ehsan, Sean R Wilson, John Goncalves, Robert Levitt, Chiwon Hahn, Puja Parikh, Thomas Bilfinger, David Butzel, Scott Buchanan, Nicholas Hanna, Robert Garrett, Maurice Buchbinder, Federico Asch, Gaby Weissman, Itsik Ben-Dor, Christian Shults, Roshni Bastian, Paige E Craig, Syed Ali, Hector M Garcia-Garcia, Paul Kolm, Quan Zou, Lowell F Satler, and Toby Rogers

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Anthracycline and peripartum cardiomyopathies., Joshua A Cowgill, Sanjeev A Francis, and Douglas B Sawyer

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Clinician diagnoses of failure to thrive before and after switch to World Health Organization growth curves., Carrie Daymont, Noah Hoffman, Eric W Schaefer, and Alexander G Fiks

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Sialyltransferase inhibition leads to inhibition of tumor cell interactions with E-selectin, VCAM1, and MADCAM1, and improves survival in a human multiple myeloma mouse model., Alessandro Natoni, Mariah L Farrell, Sophie Harris, Carolyne Falank, Lucy Kirkham-McCarthy, Matthew S Macauley, Michaela R Reagan, and Michael O'Dwyer

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Cancer genetic health communication in families tested for hereditary breast/ovarian cancer risk: a qualitative investigation of impact on children's genetic health literacy and psychosocial adjustment., Kenneth P Tercyak, Suzanne M Bronheim, Nicole Kahn, Hillary A Robertson, Bruno J Anthony, Darren Mays, Suzanne C O'Neill, Susan K Peterson, Susan Miesfeldt, Beth N Peshkin, and Tiffani A DeMarco

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Neurological pupil index and pupillary light reflex by pupillometry predict outcome early after cardiac arrest., Richard R Riker, Mary E Sawyer, Victoria G Fischman, Teresa May, Christine Lord, Ashley Eldridge, and David B Seder

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Enhancing Interprofessional Collaboration and Communication with Art, Amy Moore and Dina McKelvy

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ACR appropriateness criteria nonatherosclerotic peripheral artery disease., Christopher J Francois, Erik P Skulborstad, Sanjeeva P Kalva, Bill S Majdalany, Jeremy D Collins, Jens Eldrup-Jorgensen, Maros Ferencik, Suvranu Ganguli, A Tuba Kendi, Minhajuddin S Khaja, Piotr Obara, Thomas Ptak, Stephen P Reis, Patrick D Sutphin, and Karin E Dill

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A Lesson in Screening For Hereditary Kidney Cancer Syndromes., Cindy Curry

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Analysis of anti-diabetic exosomes secreted from beige adipocytes, Rachelle Mendola, Chad Doucette, Daniel Nguyen, Su Su, and Aaron Brown

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Analyze patient tests for importance before ordering., Steven H Horowitz

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Characteristics of Inpatients with Opioid Use Disorder Seen by “IMAT” Consult Service from 7/2016 - 6/2017, Katherine Nenninger, Jenny Carwile, Jonathan Fellers, and Kinna Thakarar

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Clinical features and outcomes of young patients with epithelioid sarcoma: an analysis from the Children's Oncology Group and the European paediatric soft tissue Sarcoma Study Group prospective clinical trials., Sheri L. Spunt, Nadine Francotte, Gian Luca De Salvo, Yueh-Yun Chi, Ilaria Zanetti, Andrea Hayes-Jordan, Simon C. Kao, Daniel Orbach, Bernadette Brennan, Aaron R. Weiss, Max M. van Noesel, Lynn Million, Rita Alaggio, David M. Perham, Anna Kelsey, R Lor Randall, M Beth McCarville, Gianni Bisogno, Douglas S. Hawkins, and Andrea Ferrari

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Communicating uncertainty in cancer prognosis: A review of web-based prognostic tools., Mark Harrison, Paul K J Han, Borsika Rabin, Madelaine Bell, Hannah Kay, Luke Spooner, Stuart Peacock, and Nick Bansback

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Community oncology clinicians’ knowledge, beliefs, and attitudes regarding genomic tumor testing, Eric Anderson, Alexandra Hinton, Kimberly Murray, Hayley Mandeville, Caitlin Gutheil, Leo Waterston, Lee Lucas, Christine Duarte, Christian Thomas, Susan Miesfeldt, Petra Helbig, Andrey Antov, Jens Rueter, and Paul Han

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Comparison of Intraoperative Tranexamic Acid and Epsilon-aminocaproic Acid in Cardiopulminary Bypass Patients: A Natural Experiment, Mike Robich

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Delayed Initiation of Therapeutic Hypothermia for Outborn Infants is Associated with Adverse Outcomes, Nabeel Hashmi, Max Sale, Leah Fox, Jay Kerecman, Lauren McAllister, Misty Melendi, and Frances Lucas

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Development of 3D adipose tissue organoids to model human perivascular adipose tissue development and dysfunction, Joshua Boucher and Lucy Liaw

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Effect of a Robust Electronic Medical Record Order Set on Hepatitis C Screening Rate at a Community Hospital, Hannah Olsen, Caroline Knight, and Harold Van Lonkhuyzen

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Feasibility of a lifestyle change group medical visit in primary care, Booth Dargis

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Feasibility of pre-operative mTOR inhibitor Sirolimus in children and young adults with desmoid tumor, Stephanie Verwys, Clara Magyar, Kathleen Glick, Douglas Hawkins, Archana Sharma, Brenda Weigel, Katherine Chastain, Joseph Khoury, Michele Manalang, Sarah Dry, Noah Federman, and Aaron Weiss

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Gestational Age, Birth Weight, and Outcomes Six Years After the Norwood Procedure., Thomas Miller, Nancy S Ghanayem, Jane W Newburger, Brian W McCrindle, Chenwei Hu, Aaron G DeWitt, James F Cnota, Felicia L Tractenberg, Victoria L Pemberton, Michael J Wolf, Jodie K Votava-Smith, Carlen G Fifer, Linda M Lambert, Amee Shah, Eric M Graham, Christian Pizarro, Jeffrey P Jacobs, Stephen G Miller, L LuAnn Minich, and Pediatric Heart Network Investigators

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Getting Personal with Dementia: Physician Assistant Student Virtual Reality Immersion, Diane Visich, Dana Vilmore, and Elizabeth Dyer

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Identifying Youth at Clinical High Risk: What’s the Emotional Impact?, K A. Woodberry, K S. Powers, C Bryant, D Downing, M Verdi, L Kennedy, D I. Shapiro, R Girgis, G Brucato, D Huang, F M. Crump, C M. Corcoran, L I. Seidman, B Link, W R. McFarlane, and L Yang

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Impact of palliative care consultations for patients admitted to Maine Medical Center with acute exacerbations of COPD, Benjamin Jarrett, Isabella Strumpf, and Rebecca Hutchinson

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Increasing Doses of Intraoperative Hydromorphone Do Not Reduce Postoperative Pain, Craig S. Curry, Michael B. Henry, Wendy Craig, Janelle M. Richard, and Denham S. Ward

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Loperamide-Associated Opioid Use Disorder and Proposal of an Alternative Treatment with Buprenorphine., Lee A Wolfrum, Aimee S Nordmeyer, Christopher W Racine, and Stephanie D Nichols

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Missing pieces of the retention puzzle., Tammy Whitney-Dumais and Kristiina Hyrkäs

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Mobilizing older adults: A multi-site, exploratory and observational study on patients enrolled in the Hospital Elder Life Program (HELP)., Rhonda L. Babine, E Kristiina Hyrkäs, Caitlin G. McKenzie, and Heidi R. Wierman

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Mobilizing older adults: A multi-site, exploratory and observational study on patients enrolled in the Hospital Elder Life Program (HELP)., Rhonda L Babine, Kristiina E Hyrkäs, Caitlin G Mckenzie, and Heidi R Wierman

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Neurocardiac risk stratification 6 hours after resuscitation from cardiac arrest, A Bilkanovic, Z Haxhija, L Lucas, J Dziodzio, R R. Riker, T May, H Friberg, and D B. Seder

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Northern New England Palliative Care Teleconsult Research Laboratory, Ava Daruvala, Rebecca N. Hutchinson, Eric Anderson, and Paul Han

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Outcomes of Implementation of an Evidence-Based Enteral Feeding Protocol in Neonates Weighing Less Than 1800g at Birth, Rebecca Edwards

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Outpatient naloxone prescription in adults at risk for overdose in Cumberland County, Maine, David Kispert, Jenny Carwile, and Kinna Thakarar

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Outpatient Treatment of Pulmonary Embolism: A Single-Center Case Series, Annie Huyler, Casey Z. MacVane, Andrew Perron, and Tania D Strout

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Per- and Polyfluoroalkyl Substances and Bone Mineral Density in Mid-childhood, Shravanthi M. Seshasayee, Rachel Cluett, Lisa B. Rokoff, Sheryl L. Rifas-Shiman, Diane R. Gold, Brent Coull, Catherine M. Gordon, Clifford J. Rosen, Emily Oken, Sharon K. Sagiv, and Abby F. Fleisch

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Pharmacological Management of Osteoporosis in Postmenopausal Women: An Endocrine Society* Clinical Practice Guideline., Richard Eastell, Clifford J Rosen, Dennis M Black, Angela M Cheung, M Hassan Murad, and Dolores Shoback

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Physician-patient communication about genomic tumor testing: perceptions of oncology providers, Hayley Mandeville, Eric Anderson, Kimberly Murray, Caitlin Gutheil, Leo Waterston, Lee Lucas, Christine Duarte, Christian Thomas, Susan Miesfeldt, Petra Helbig, Andrey Antov, Jens Rueter, and Paul Han

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Pioglitazone Therapy in Patients With Stroke and Prediabetes: A Post Hoc Analysis of the IRIS Randomized Clinical Trial., J David Spence, Catherine M Viscoli, Silvio E Inzucchi, Jennifer Dearborn-Tomazos, Gary A Ford, Mark Gorman, Karen L Furie, Anne M Lovejoy, Lawrence H Young, Walter N Kernan, and IRIS Investigators

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Post Lumbar-Puncture Headache Experience in a Community Hospital (PEACH) Study, Melissa Kessel, Caroline Knight, and Robert Stein

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Potential of vascular endothelial growth factor as a biomarker of coronary artery disease in subjects undergoing CABG surgery, Teaka Jackson, Sarah Peterson, Amanda Favreau-Lessard, Joanne Burgess, Susan Bosworth-Farrell, Robert S. Kramer, Douglas B. Sawyer, Sergey Ryzhov, and Michael P. Robich

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Predictors for Discharge After Robotic Hysterectomy – A Retrospective Analysis, Heidi Fox and Kristiina Hyrkas

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Primary cilia of the cardiac neural crest orchestrate critical aspects of ventricular myocardial maturation and postnatal cardiac function, Lindsey Fitzsimons

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Prions to Pathways: Safeguarding Against Creutzfeldt-Jakob Disease in the Operating Room, Jessica Mary Adams Atkinson and Sonja Carol Orff

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Problematic Internet Use and Associated High-Risk Behavior in an Adolescent Clinical Sample: Results from a Survey of Psychiatrically Hospitalized Youth., Meredith Gansner, Erin Belfort, Benjamin Cook, Caroline Leahy, Andrea Colon-Perez, Danielle Mirda, and Nicholas Carson

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Reducing Catheter Associated Urinary Tract Infections (CAUTI) by Decreasing Use of Indwelling Catheters, Joanne Chapman, Brenda Clark, Brian Jumper, and Carrie Strick

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Reducing Length of Stay for Mental Health Patients, Faye Collins and Nancijean Goudey

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Scaffolding kidney organoids on silk., Ashwani Kumar Gupta, Jeannine M Coburn, Jessica Davis-Knowlton, Erica Kimmerling, David L Kaplan, and Leif Oxburgh

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Seerratus Anterior Plane Block (SAPB) Improves Paine Control in Rib Fractures, Randy Kring, Peter Croft, David Mackenzie, Christina Wilson, Joseph Rappold, and Tania D. Strout

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Social influence and moment-to-moment changes in young adults’ mood and psychotic symptoms, K Powers, K A. Johnson, M Graham, A Cloutier, K Stewart, S Lynch, D Robbins, R Mesholm-Gately, and K A. Woodberry

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Ten-year Outcomes of Cervical Disc Replacement With the BRYAN Cervical Disc: Results From a Prospective, Randomized, Controlled Clinical Trial., William F Lavelle, K Daniel Riew, Allan D Levi, and Jeffrey E Florman

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The association between feeding protocol compliance and weight gain following high-risk neonatal cardiac surgery., Jamie M Furlong-Dillard, Benjamin J Miller, Kathy A Sward, Alaina I Neary, Trudy L Hardin-Reynolds, Grace Jeffers, Bonnie A Clay, Dongngan T Truong, Thomas Miller, Courtney E Jones, Linda M Lambert, and David K Bailly

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The effect of beta blocker use on bone outcomes using the Framingham Osteoporosis Study, Christine Lary

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The Functional Food Diet: A Pilot Study, Caroline Knight and Ralph Hamill

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The Innovations Cohort, Jennifer Monti

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The relationship between uncertainty tolerance and oncologists’ perceptions of large-panel genomic tumor testing, Eric Anderson, Alexandra Hinton, Christine Lary, Kimberly Murray, Leo Waterson, Paul Han, and Maine Cancer Genomics Initiative

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Using Social Media to Broaden Understanding of the Barriers and Facilitators to Exercise in Adults With Type 1 Diabetes., Tamara K Oser, Kaitlin A Minnehan, Glenna Wong, Jessica Parascando, Erin McGinley, Julie Radico, and Sean M Oser

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Validity of neonatal POC glucose testing, Matthew Turnquist, Amy Haskins, and Christina Holt

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Wellness in Teaching: a dynamic educational intervention to improve faculty performance, Sue Rose, Vicki Hayes, Christine Hein, Amy Sedgwick, Bryan Lamoreau, and Wendy Craig

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What’s Happening to our Patients in their Final Year of Life?, Teresa Letellier, Amy Haskins, and Christina Holt

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Where we were, where we are, and where are we going? The state of research at MaineHealth, Clifford J. Rosen

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Young Man With Hip Injury., Matthew J Spanier and David C Mackenzie

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Microvascular and systemic impact of resuscitation with pegylated carboxyhemoglobin-based oxygen carrier or hetastarch in a rat model of transient hemorrhagic shock., William H Nugent, Forest R Sheppard, Michael A Dubick, Ramon F Cestero, Daniel N Darlington, Ronald Jubin, Abe Abuchowski, and Bjorn K Song

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Patients' responses to incidentally discovered silent brain infarcts - a qualitative study., Lester Y Leung, Paul K J Han, Christine Lundquist, Gene Weinstein, David E Thaler, and David M Kent

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AO Patient Outcomes Center: Design, Implementation, and Evaluation of a Software Application for the Collection of Patient-Reported Outcome Measures in Orthopedic Outpatient Clinics., Nan E Rothrock, Michael Bass, Andrea Blumenthal, Richard C Gershon, Beate Hanson, Alexander Joeris, Aaron Kaat, Suzanne Morrison, Robert V O'Toole, Shalini Patel, Michael Stover, Michael J Weaver, Raymond White, Maria Varela Diaz, and Mark S Vrahas

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Letter to the Editor., James R Rodrigue, Aaron Fleishman, Claire M Sokas, Jesse D Schold, Paul Morrissey, James Whiting, John Vella, Liise K Kayler, Daniel Katz, Jody Jones, Bruce Kaplan, Martha Pavlakis, and Didier A Mandelbrot

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Association between the food and physical activity environment, obesity, and cardiovascular health across Maine counties., Allison C Briggs, Adam W Black, F Lee Lucas, Andrea E Siewers, and Kathleen M Fairfield

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Pharmacist-Managed Inpatient Dofetilide Initiation Program: Description and Adherence Rate Post-Root Cause Analysis., Elena You Jung Ko, Charles M Carpenter, David J Gagnon, and Anne M Andrle

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A Comprehensive Update on Treatment of Dementia., Annya Tisher and Arash Salardini

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Are children severely affected by autism spectrum disorder underrepresented in treatment studies? An analysis of the literature, Amy Stedman, Matthew Siegel, Briana Taylor, Michael Erard, and Christine Peura

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Associations of protein intake in early childhood with body composition, height, and insulin-like growth factor I in mid-childhood and early adolescence., Karen M. Switkowski, Paul F. Jacques, Aviva Must, Abby Fleisch, and Emily Oken

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Body composition and bone mineral density in childhood., Lisa B Rokoff, Sheryl L Rifas-Shiman, Karen M Switkowski, Jessica G Young, Clifford J Rosen, Emily Oken, and Abby F Fleisch

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Editorial Comment., Jesse Sammon

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Management of Post-transplant Hyperparathyroidism and Bone Disease., Rowena Delos Santos, Daniel Coyne, Ana Rossi, and Thin Thin Maw

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Pulmonary hypertension subjects exhibit right ventricular transient exertional dilation during supine exercise stress echocardiography., Rama El-Yafawi, David Rancourt, Melkon Hacobian, Dennis Atherton, Mylan C Cohen, and Joel A Wirth

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Resistance to visceral obesity is associated with increased locomotion in mice expressing an endothelial cell-specific fibroblast growth factor 1 transgene., Tyler Keeley, Aleksandr Kirov, Woon Yuen Koh, Victoria Demambro, Ivy Bergquist, Jessica Cotter, Peter Caradonna, Matthew E Siviski, Bradley Best, Terry Henderson, Clifford J Rosen, Lucy Liaw, Igor Prudovsky, and Deena J Small

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Senescent and apoptotic osteocytes and aging: Exercise to the rescue?, Vanessa D Sherk and Clifford J Rosen

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Tolerating uncertainty about conceptual models of uncertainty in health care., Paul K.J. Han and Benjamin Djulbegovic

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Tranexamic acid suppresses the release of mitochondrial DAMPs and reduces lung inflammation in a murine burn model., Damien Wilson Carter, Igor Prudovsky, Doreen Kacer, Tee Soul, Chloe Kumpel, Kathleen Pyburn, Monica Palmeri, Robert Kramer, and Joseph Rappold

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Vertical transmission rates of Borrelia miyamotoi in Ixodes scapularis collected from white-tailed deer., Seungeun Han, Charles Lubelczyk, Graham J Hickling, Alexia A Belperron, Linda K Bockenstedt, and Jean I Tsao

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Intestinal clock system regulates skeletal homeostasis., Masanobu Kawai, Saori Kinoshita, Miwa Yamazaki, Keiko Yamamoto, Clifford J Rosen, Shigeki Shimba, Keiichi Ozono, and Toshimi Michigami

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Differentiation Capacity of Human Aortic Perivascular Adipose Progenitor Cells., S Spencer Scott, Xuehui Yang, Michael Robich, Lucy Liaw, and Joshua M Boucher

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Abdominal Pain After a Football Game., Heidi M Goddard, Casey Z MacVane, and Tania D Strout

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Achievement of Guideline-Recommended Weight Loss Among Patients With Ischemic Stroke and Obesity., Jennifer L Dearborn, Catherine M Viscoli, Lawrence H Young, Mark J Gorman, Karen L Furie, and Walter N Kernan

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A randomized phase II study of cabozantinib versus weekly paclitaxel in the treatment of persistent or recurrent epithelial ovarian, fallopian tube or primary peritoneal cancer: An NRG Oncology/Gynecologic Oncology Group study., Ursula A Matulonis, Michael W Sill, Vicky Makker, David G Mutch, Jay W Carlson, Christopher J Darus, Robert S Mannel, David P Bender, Erin K Crane, and Carol Aghajanian

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Assessing feasibility of resources at health facilities in Uganda to diagnose pregnancy and neonatal outcomes., James H Stark, Eve Wool, Lena Tran, Elizabeth Robinson, Meaghan Chemelski, Daniel Weibel, Wan-Ting Huang, Sonali Kochhar, Janet R Hardy, Steven Bailey, Edward Galiwango, and Dan Kajungu

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A systematic review of micronutrient deficiencies in pediatric inflammatory bowel disease., Julia Fritz, Cassandra Walia, Abdul Elkadri, Rebecca Pipkorn, Rachel K. Dunn, Rita Sieracki, Praveen S. Goday, and Jose Mariano Cabrera

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Characterization of smooth muscle cells from human atherosclerotic lesions and their responses to Notch signaling., Jessica Davis-Knowlton, Jacqueline E Turner, Anna Turner, Sydney Damian-Loring, Nicholas Hagler, Terry Henderson, Ivette F Emery, Kyle Bond, Christine W Duarte, Calvin P H Vary, Jens Eldrup-Jorgensen, and Lucy Liaw

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Do we need continuous electroencephalography after cardiac arrest?, Teresa May, Richard R. Riker, and David Seder

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Inpatient Psychiatric Treatment of Serious Behavioral Problems in Children with Autism Spectrum Disorder (ASD): Specialized Versus General Inpatient Units., Briana J. Taylor, Kevin B. Sanders, Marie Kyle, Kahsi A. Pedersen, Jeremy Veenstra-Vanderweele, and Matthew Siegel

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Interactions with Muscle Cells Boost Fusion, Stemness, and Drug Resistance of Prostate Cancer Cells., Berna Uygur, Evgenia Leikina, Kamran Melikov, Rafael Villasmil, Santosh K Verma, Calvin P H Vary, and Leonid V Chernomordik

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Multiple Myeloma and Fatty Acid Metabolism., Majdi Masarwi, Abigail DeSchiffart, Justin Ham, and Michaela R Reagan

Point-of-Care versus Central Laboratory Glucose Testing in Postoperative Cardiac Surgery Patients., Robert S. Kramer, Monica Palmeri, Michael Robich, Frances L. Lucas, Robert Groom, Timothy Hayes, Marie Janoushek, Joseph F. Rappold, William L. Swartz, and Reed Quinn

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Prognostic value of a modified surprise question designed for use in the emergency department setting., Samir A Haydar, Tania D Strout, Alicia G Bond, and Paul Kj Han

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Why Residents Quit: National Rates of and Reasons for Attrition Among Emergency Medicine Physicians in Training., Dave W. Lu, Nicholas D. Hartman, Jeffrey Druck, Jennifer Mitzman, and Tania D. Strout

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An Analysis of Psychoactive Medications Initiated in the ICU but Continued Beyond Discharge: A Pilot Study of Stewardship., Nicole Lynn Kovacic, David J Gagnon, Richard R Riker, Sijin Wen, and Gilles L Fraser