Incorporated in 1868, MMC is the state’s largest medical center, licensed for 700 beds and employing more than 9,600 people. MaineHealth Maine Medical Center’s unique role as both a community hospital and a referral center requires an unparalleled depth and breadth of services, including the state’s only allopathic medical school program, through a partnership with Tufts University School of Medicine, and a world-class biomedical research center, the MaineHealth Institute for Research.

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Submissions from 2022

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Mapping Melanoma Risk and Locating High-Need Regions for Dermoscopy and Skin Biopsy Training, Calla Hladky, Madeline Prentiss, Henry Stoddard, Kathryn Stevens, Elizabeth Seiverling, and Peg Cyr

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Medication for Addiction Treatment and Postpartum Health Care Utilization Among Pregnant Persons With Opioid Use Disorder, Katherine A. Ahrens, Carole A. McBride, Alane O'Connor, and Marjorie C. Meyer

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Microclimate conditions alter Ixodes scapularis (Acari: Ixodidae) overwinter survival across climate gradients in Maine, United States, Michelle R. Volk, Charles B. Lubelczyk, Jason C. Johnston, Danielle L. Levesque, and Allison M. Gardner

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Mouse models of development and disease: Preface, Thomas Gridley and Leif Oxburgh

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Mouse mutagenesis and phenotyping to generate models of development and disease, Thomas Gridley and Stephen A. Murray

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Quantification of Lipid Area within Thermogenic Mouse Perivascular Adipose Tissue Using Standardized Image Analysis in FIJI, Benjamin W. Tero, Bethany Fortier, Ashley N. Soucy, Ginger Paquette, and Lucy Liaw

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Regional brain development in fetuses with Dandy-Walker malformation: A volumetric fetal brain magnetic resonance imaging study, Shizuko Akiyama, Neel Madan, George Graham, Osamu Samura, Rie Kitano, Hyuk Jin Yun, Alexa Craig, Tomohiro Nakamura, Atsushi Hozawa, Ellen Grant, Kiho Im, and Tomo Tarui

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Sexual Orientation and Age at Menarche in Three U.S. Longitudinal Cohorts, Brittany M. Charlton, Jenny L. Carwile, Jorge E. Chavarro, Amy D. DiVasta, Najat J. Ziyadeh, and S Bryn Austin

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Smad4 controls proliferation of interstitial cells in the neonatal kidney, Sarah S. McCarthy, Michele Karolak, and Leif Oxburgh

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"TEACH"ing Medical Students to Address Child Poverty: A Multimodal Curriculum, Jessica Weisz, Paula Magee, Iana Clarence, Mary Ottolini, and Olanrewaju O. Falusi

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"TEACH"ing Medical Students to Address Child Poverty: A Multimodal Curriculum., Jessica Weisz, Paula Magee, Iana Clarence, Mary Ottolini, and Olanrewaju O Falusi

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The Dangers of ACEs, Olivia Carey, Thea Forrest, and Adna Abdi

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The effect of short-term high-caloric feeding and fasting on bone microarchitecture, Miriam A. Bredella, Pouneh K. Fazeli, Jenna Bourassa, Clifford J. Rosen, Mary L. Bouxsein, Anne Klibanski, and Karen K. Miller

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The Implications of Bone Marrow Adipose Tissue on Inflammaging, Nicole Aaron, Samantha Costa, Clifford J. Rosen, and Li Qiang

Submissions from 2021

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Heterozygous Truncating Mutation of Nucleolin in an ASD Individual Disrupts Its Nucleolar Localization, Taimoor I. Sheikh, Ricardo Harripaul, Nasim Vasli, Majid Ghadami, Susan L. Santangelo, Muhammad Ayub, Roksana Sasanfar, and John B. Vincent

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Hispanic/Latino-Serving Hospitals Provide Less Targeted Temperature Management Following Out-of-Hospital Cardiac Arrest, Nicholas A. Morris, Michael Mazzeffi, Patrick McArdle, Teresa L. May, Greer Waldrop, Sarah M. Perman, James F. Burke, and Steven M. Bradley

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Vascular Quality Initiative Surveillance of Femoropopliteal Artery Paclitaxel Devices, Daniel J. Bertges, Jens Eldrup-Jorgensen, Susan Robbins, Henry Ssemaganda, Misti Malone, Danica Marinac-Dabic, Joshua Smale, Aaron E. Lottes, Arjun Majithia, and Frederic S. Resnic

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"Sick or not sick?" A mixed methods study evaluating the rapid determination of illness severity in a pediatric emergency department., Laura B O'Neill, Priti Bhansali, James E Bost, James M Chamberlain, and Mary C Ottolini

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Emotional and stigma-related experiences relative to being told one is at risk for psychosis, Kristen A. Woodberry, Kate S. Powers, Caitlin Bryant, Donna Downing, Mary B. Verdi, Katherine M. Elacqua, Audrey R. Reuman, and Leda Kennedy

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Family planning in carriers of BRCA1 and BRCA2 pathogenic variants, Jessica M. Haddad, Katina Robison, Lindsey Beffa, Jessica Laprise, Jennifer ScaliaWilbur, Christina A. Raker, Melissa A. Clark, and Erin Hofstatter

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DEspR neutrophils are associated with critical illness in COVID-19, Joanne T. deKay, Ivette F. Emery, Jonathan Rud, Ashley Eldridge, Christine Lord, David J. Gagnon, and Teresa L. May

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Emphasizing the Link Between Human Health and the Environment in Residency Education., Lesley B. Gordon and Katherine Liu

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Management of blunt traumatic abdominal wall hernias: A Western Trauma Association multicenter study, Kevin N. Harrell, Arthur D. Grimes, Roxie M. Albrecht, Jessica K. Reynolds, Walker R. Ueland, Daniel Cullinane, and Carolyne Falank

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Prescription opioid policies and associations with opioid overdose and related adverse effects, Valerie S. Harder, Susan E. Varni, Kimberly A. Murray, Timothy B. Plante, Andrea C. Villanti, Daniel L. Wolfson, and Sanchit Maruti

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Prospective associations of mid-childhood plasma per- and polyfluoroalkyl substances and pubertal timing., Jenny L Carwile, Shravanthi M Seshasayee, Izzuddin M Aris, Sheryl L Rifas-Shiman, Birgit Claus Henn, Antonia M Calafat, Sharon K Sagiv, Emily Oken, and Abby F Fleisch

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Quantitative trait locus mapping identifies a locus linked to striatal dopamine and points to collagen IV alpha-6 chain as a novel regulator of striatal axonal branching in mice, Mélanie H. Thomas, Yujuan Gui, Pierre Garcia, Mona Karout, Borja Gomez Ramos, Christian Jaeger, Alessandro Michelucci, and Anthoula Gaigneaux

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The Future Nephrology Workforce: There Will Be One, Mark G. Parker and Stephen M. Sozio

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Leveraging Improvement Capacity for Organization Strategy Deployment, Suneela Nayak, Natalia Johnson, Rebecca A. Brookes, and Andrew Levine

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Pandemic Pearl: Innovations in Virtual Improvement Coaching, Suneela Nayak, Natalia Johnson, Rebecca Brookes, and Andrew Levine

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Supporting an Advanced Practice Provider (APP) Residency Program, Dina McKelvy

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Myocarditis in the Setting of Recent COVID-19 Vaccination., Laura Onderko, Benjamin Starobin, Amy E Riviere, Patrick K Hohl, Colin T Phillips, Roisin B Morgan, Aimee Welsh, Sanjeev A Francis, and Maxwell Eyram Afari

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Evaluating Health Economic Outcomes of Autologous Skin Cell Suspension for Definitive Closure in US Burn Care Using Contemporary Real-World Burn Center Data, K Foster, A Amani, Damien Carter, J Griswold, and B Hickerson

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CLER Pursuing Excellence: Faculty Development Innovations in Quality, Safety, Equity, and Value., Lei W Choi, Christopher Moriates, Asha S Payne, Kalli Varaklis, Ralph Gonzales, and Robert B Baron

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Factorial Analysis Quantifies the Effects of Pediatric Discharge Bundle on Hospital Readmission., Snezana Nena Osorio, Sandra Gage, Leah Mallory, Paula Soung, Alexandra Satty, Erika L Abramson, Lloyd Provost, and David Cooperberg

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Supporting families in their child's journey with neonatal encephalopathy and therapeutic hypothermia, Betsy Pilon, Alexa K. Craig, Monica E. Lemmon, and Annie Goeller

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Urinary stone disease prevalence and associations in cystic fibrosis., Jeremy F Wright, Wendy Craig, F L Lucas, David S Goldfarb, Jonathan B Zuckerman, and Eric N Taylor

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Training in neonatal neurocritical care: a proposal for a hybrid model of competence by design and time-based methods., Khorshid Mohammad, Alexa K. Craig, Taeun Chang, Emily W Y Tam, Mariam Ayed, Linda S de Vries, Mohamed A El-Dib, Michael J Esser, Donna M Ferriero, Lena Hellström-Westas, Steven P Miller, Janet S Soul, Brigitte Vollmer, Hannah C Glass, and Christopher D Smyser

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How Well Does the Surprise Question Predict 1-year Mortality for Patients Admitted with COPD?, Dana Tripp, Jaclyn Janis, Benjamin Jarrett, F Lee Lucas, Tania D. Stout, Paul K J Han, Isabella Stumpf, and Rebecca N. Hutchinson

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Notch1 and Notch2 collaboratively maintain radial glial cells in mouse neurogenesis, Shun Mase, Atsunori Shitamukai, Quan Wu, Mitsuru Morimoto, Thomas Gridley, and Fumio Matsuzaki

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A Cystic Renal Mass in the Setting of a Pneumothorax: More Than Meets the Eye?, Daniel S. Han, David J. Chalmers, Brian Greffe, Timothy Garrington, David Partrick, Mark Lovell, Kami Wolfe Schneider, and Nicholas G. Cost

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The influence of uncertainty and uncertainty tolerance on attitudes and self-efficacy about genomic tumor testing, Eric C. Anderson, Alexandra Hinton, Christine W. Lary, Tania Strout, Andrey Antov, Emily Edelman, Petra Helbig, Kate Reed, Jens Rueter, and Paul K. Han

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Management of Minor Traumatic Brain Injury in an ED Observation Unit, Matthew A. Wheatley, Shikha Kapil, Amanda Lewis, Jessica Walsh O'Sullivan, Joshua Armentrout, Tim P. Moran, Anwar Osborne, Brooks L. Moore, Bryan Morse, Peter Rhee, Faiz Ahmad, and Hany Atallah

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Decreasing Unplanned Extubations in the Neonatal ICU, Deborah A. Igo, Kimberly Kingsley, Elisabeth Malaspina, and Alan Picarillo

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Influence of Opioid Prescription Policy on Overdoses and Related Adverse Effects in a Primary Care Population, Valerie S. Harder, Timothy B. Plante, Insu Koh, Ethan B. Rogers, Susan E. Varni, Andrea C. Villanti, John R. Brooklyn, and Kathleen Fairfield

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Outcomes after ultramassive transfusion in the modern era: An Eastern Association for the Surgery of Trauma multicenter study, Zachary A. Matthay, Zane J. Hellmann, Rachael A. Callcut, Ellicott C. Matthay, Brenda Nunez-Garcia, Daniel Cullinane, and Julianne Ontengco

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Patient and family perceptions of an inpatient journal, Marguerite Peggy Anderson and Kristiina Hyrkas

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Patients over 65 years with Acute Complicated Calculous Biliary Disease are Treated Differently-Results and Insights from the ESTES Snapshot Audit, Gary A. Bass, Amy E. Gillis, Yang Cao, Shahin Mohseni, and Daniel Cullinane

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Transdiaphragmatic Chest Wall Herniation, Anna G. Meader, David L. Ciraulo, Joseph F. Rappold, and Jaswin S. Sawhney

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Treating the endotheliopathy of SARS-CoV-2 infection with plasma: Lessons learned from optimized trauma resuscitation with blood products, Shibani Pati, Erin Fennern, John B. Holcomb, Mark Barry, Alpa Trivedi, and Joseph Rappold

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Young Man with Swollen Knee., Nicholas Fling and Andrew Fried

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Can hospital adult code-teams and individual members perform high-quality CPR? A multicenter simulation-based study incorporating an educational intervention with CPR feedback, Jesse M. Rideout, Edwin Ozawa, Darlene Bourgeois, Micheline Chipman, and Frank Overly

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Computer-aided learning for managing stress: A feasibility trial with clinical high risk adolescents and young adults, Kristen A. Woodberry, Cole Chokran, Kelsey A. Johnson, Keith H. Nuechterlein, David J. Miklowitz, Stephen V. Faraone, and Larry J. Seidman

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Poststent ballooning during transcarotid artery revascularization, Hanaa Dakour-Aridi, Christina L. Cui, Andrew Barleben, Marc L. Schermerhorn, Jens Eldrup-Jorgensen, and Mahmoud B. Malas

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Severity and patterns of injury in helmeted vs. non-helmeted motorcyclists in a rural state, Sivana Barron, Carolyne Falank, Julianne Ontengco, Bruce Chung, and Damien Carter

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The Value of Adapting Clinical Reasoning Teaching Methods, Devin Carr

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Barriers and Opportunities to Improve the Medical Education Experience in an Interprofessional Educational Setting: An Application of Concept Mapping, Motahareah Tavakolikashi, Lesley B. Gordon, Sarah Hallen, Melissa Zelaya-Floyd, and Patricia White

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Bring Resident Physicians to the Bedside to Foster High Quality Evaluations, Lesley B. Gordon, Sarah Hallen, Kalli Varaklis, Melissa Zelaya-Floyd, and Patricia White

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Management of simple and retained hemothorax: A practice management guideline from the Eastern Association for the Surgery of Trauma, Nimitt J. Patel, Linda Dultz, Husayn A. Ladhani, Daniel C. Cullinane, and Eric Klein

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Physical Therapy, Occupational Therapy, and Speech Language Pathology in the Emergency Department: Specialty Consult Services to Enhance the Care of Older Adults, Elizabeth Pontius and Rob Anderson

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Third trimester maternal vitamin D and early childhood socioemotional development, Ellen C. Francis, Elizabeth Charron, Mengying Li, Liwei Chen, Rachel Mayo, Linda S. Butler, and Lior Rennert

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Roundtable on Preseason Heat Safety in Secondary School Athletics: Prehospital Care of Patients With Exertional Heat Stroke., Kevin C Miller, Douglas J Casa, William M Adams, Yuri Hosokawa, Jason Cates, Christina Emrich, Tony Fitzpatrick, Michael Hopper, John F Jardine, Michele LaBotz, Rebecca M Lopez, Francis O'Connor, and M Seth Smith

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Physical Examination is Inadequate to Rule Out Thoracolumbar Spine Injuries in a Rural Trauma Center, Scha'Chia Murphy, Rosemary Elizabeth Paine, Carolyne Falank, Julianne Ontengco, Forest Sheppard, and Damien Carter

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Electrically Controllable Surgical Tools, Robert D. Ecker and Mohsen Shahinpoor

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Distance Learning and Spaced Review to Complement Dermoscopy Training for Primary Care., Elizabeth V Seiverling, Danielle Li, Kathryn Stevens, Peggy Cyr, Gregory Dorr, and Hadjh Ahrns

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Back to the Bedside: Interprofessional, Bedside Rounding Improves the Quality of Narrative Evaluations, Kalli Varaklis, Thomas Van der Kloot, Sarah Hallen, Thomas Gearan, Beth Wilson, Lesley B. Gordon, Melissa Zelaya-Floyd, Patricia White, and Motahareh Tavakolikashi

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Corrigendum to "Maternal opioid use disorder at delivery hospitalization in a rural state: Maine, 2009-2018" [Public Health 181C (2020) 171-179]., Sarah M. Gabrielson, J L Carwile, A B O'Connor, and K A Ahrens

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End-of-Life Care: Improving Communication and Reducing Stress, Joan Carr Myers and Kristiina Hyrkas

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Medical student perspectives on conducting patient experience debrief interviews with hospitalized children and their families, Ian S. Chua, Alyssa L. Bogetz, Michele Long, Terry Kind, Mary Ottolini, Matthew Lineberry, and Priti Bhansali

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FOXD1 regulates cell division in clear cell renal cell carcinoma, Kyle H. Bond, Jennifer L. Fetting, Christine W. Lary, Ivette F. Emery, and Leif Oxburgh

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Efficacy of Sex Steroid Therapy Without Progestin or GnRH Agonist for Gonadal Suppression in Adult Transgender Patients., India I Pappas, Wendy Craig, Lindsey V Spratt, and Daniel I Spratt

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Case Report of Cardiopulmonary Arrest During Pregnancy due to Opioid Overdose, Tracey E. McMillan, Sarah Austin, and Kristiina Hyrkas

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Increasing intraoperative hydromorphone does not decrease postoperative pain: a retrospective observational study., Craig S Curry, Wendy Craig, Janelle M Richard, and Denham S Ward

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Multicystic Dysplastic Kidney With Mass Effect in a Neonate Treated With Nephrectomy: Case Report, Samuel M. Pettit, William J. Devan, David J. Chalmers, and Allison Zanno

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Pediatric Hospitalists' Performance and Perceptions of Script Concordance Testing for Self-Assessment, Mary C. Ottolini, Ian Chua, Joyce Campbell, Martin Ottolini, and Ellen Goldman

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Per- and polyfluoroalkyl substance plasma concentrations and metabolomic markers of type 2 diabetes in the Diabetes Prevention Program trial, Susanna D. Mitro, Jinxi Liu, Lindsay M. Jaacks, Abby F. Fleisch, Paige L. Williams, William C. Knowler, Blandine Laferrère, Wei Perng, George A. Bray, Amisha Wallia, Marie-France Hivert, Emily Oken, Tamarra M. James-Todd, and Marinella Temprosa

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Protective role of ErbB3 signaling in myeloid cells during adaptation to cardiac pressure overload, Haifeng Yin, Amanda J. Favreau-Lessard, Joanne T. deKay, Yodit R. Herrmann, Michael P. Robich, Robert A. Koza, Igor Prudovsky, Douglas B. Sawyer, and Sergey Ryzhov

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Risk factors and impact of postoperative hypotension after carotid artery stenting in the Vascular Quality Initiative, Vincent J. Noori, Nathan J. Aranson, Mahmoud Malas, Marc Schermerhorn, David O'Connor, Richard J. Powell, Jens Eldrup-Jorgensen, and Brian W. Nolan

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Support for deer herd reduction on offshore Islands of Maine, U.S.A, Susan P. Elias, Peter W. Rand, Laura N. Rickard, Benjamin B. Stone, Kirk A. Maasch, Charles B. Lubelczyk, and Robert P. Smith

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Teaching Skin Cancer Detection to Medical Students Using a Dermoscopic Algorithm., Peggy Cyr, Wendy Craig, Hadjh T. Ahrns, Kathryn Stevens, Caroline Wight, and Elizabeth Seiverling

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Myeloma-Modified Adipocytes Exhibit Metabolic Dysfunction and a Senescence-Associated Secretory Phenotype, Heather Fairfield, Amel Dudakovic, Casper M. Khatib, Mariah Farrell, Samantha Costa, Carolyne Falank, Maja Hinge, Connor S. Murphy, Victoria DeMambro, Jessica A. Pettitt, Christine W. Lary, Heather E. Driscoll, Michelle M. McDonald, Moustapha Kassem, Clifford Rosen, Thomas L. Andersen, Andre J. van Wijnen, Abbas Jafari, and Michaela R. Reagan

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Pursuing Excellence: Driving GME Integration with Health System Stategic Priorities, Elias I Traboulsi, Anita K Blanchard, Morgan Passiment, Dewesh Agrawal, Robert B Baron, Laurinda Calongne, Diane Hartmann, Jonathan MacClements, Pavan Zaveri, Kalli Varaklis, Robin Wagner, and Kevin B Weiss

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Venous thromboembolism prophylaxis in the trauma intensive care unit: an American Association for the Surgery of Trauma Critical Care Committee Clinical Consensus Document, Joseph F. Rappold, Forest R. Sheppard, Samuel P. Carmichael Ii, Joseph Cuschieri, and Eric Ley

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Addressing Physician Burnout and Ensuring High-Quality Care of the Physician Workforce, Leslie Bradford and Gretchen Glaser

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A Peer-Based Strategy to Overcome HPV Vaccination Inequities in Rural Communities: A Physical Distancing-Compliant Approach., Christine Finley, Matthew J Dugan, Jan Kirk Carney, Wendy Sue Davis, Thomas V Delaney, Victoria C Hart, Breena W Holmes, Gary S Stein, Robin Katrick, Holly Morehouse, Bernard Cole, Leslie Bradford MD, Maureen B Boardman, Heidi Considine, Nancy C Kaplan, Merideth Plumpton, Linda Schadler, Jennifer J Smith, and Kate McAllister

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Characterizing the use of osteopathic manipulative medicine in the obstetric population by trimester and indications for use., Jordan Faloon, Karly Bishop, Wendy Craig, and Julia Brock

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Emotion Dysregulation is Substantially Elevated in Autism Compared to the General Population: Impact on Psychiatric Services, Caitlin M. Conner, Josh Golt, Rebecca Shaffer, Giulia Righi, Matthew Siegel, and Carla A. Mazefsky

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Guidelines for Biobanking of Bone Marrow Adipose Tissue and Related Cell Types: Report of the Biobanking Working Group of the International Bone Marrow Adiposity Society, Stephanie Lucas, Michaela Tencerova, Benoit von der Weid, Thomas Levin Andersen, Camille Attané, Friederike Behler-Janbeck, William P. Cawthorn, and Kaisa K. Ivaska

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Guidelines for the Use and Interpretation of Assays for Monitoring Autophagy (4th edition), Anyonya R. Guntur and Contributing Author

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Hannaford Center for Safety, Innovation & Simulation 2021 Annual Report, Maine Medical Center

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Maine Medical Center Research Institute: 2021 Year in Review, Maine Medical Center Research Institute

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Merkel Cell Carcinoma of the Hand in a Young Patient, Matthew LaBarge, Ross Feller, and Amanda Keene

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Resilience of regional hospital nursing staff working during the COVID-19 pandemic measured by the Connor-Davidson resilience scale., Jill Petzel

Submissions from 2020

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Shot in the dark: three patients successfully treated with onabotulinumtoxin A injections for relief of post-traumatic chronic headaches and dystonia induced by gunshot wounds, Lauren Palitz Ferguson, Ruslan Abdukalikov, David Shbeeb, and Terence K. Gray

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Gastrocutaneous Closure Device, Jeffrey Halter, Chad P. Seeley, and Lanba Asheesh Ravikumar

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COVID-19 and Hypercoagulability: Potential Impact on Management with Oral Contraceptives, Estrogen Therapy and Pregnancy., Daniel I Spratt and Rachel J Buchsbaum

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Cryptic collagen elements as signaling hubs in the regulation of tumor growth and metastasis, XiangHua Han, Jennifer M. Caron, and Peter C. Brooks

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Endourologic Management of Stent Retained Over 22 Years in Patient with Duplicated Collecting System, William C. Daly and Johann P. Ingimarsson

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American Burn Association Guidelines on the Management of Acute Pain in the Adult Burn Patient: A Review of the Literature, a Compilation of Expert Opinion and Next Steps, Kathleen S. Romanowski, Joshua Carson, Kate Pape, Eileen Bernal, Sam Sharar, and Damien Carter

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Randomized Pilot Clinical Trial of Early Coronary Angiography Versus No Early Coronary Angiography After Cardiac Arrest Without ST-Segment Elevation: The PEARL Study, Karl B. Kern, Peter Radsel, Jacob C. Jentzer, David B. Seder, Kwan S. Lee, Kapildeo Lotun, Rajesh Janardhanan, Dion Stub, and Chiu-Hsieh Hsu

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Impact of geography and travel distance on outcomes in epithelial ovarian cancer: a national cancer database analysis., Ava Daruvala, F Lee Lucas, Jesse Sammon, Christopher Darus, and Leslie Bradford MD