Incorporated in 1868, MMC is the state’s largest medical center, licensed for 700 beds and employing more than 9,600 people. Maine Medical Center’s unique role as both a community hospital and a referral center requires an unparalleled depth and breadth of services, including the state’s only allopathic medical school program, through a partnership with Tufts University School of Medicine, and a world-class biomedical research center, the MaineHealth Institute for Research.

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Submissions from 2015

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Snai1 regulates cell lineage allocation and stem cell maintenance in the mouse intestinal epithelium., Katja Horvay, Thierry Jardé, Franca Casagranda, Victoria M Perreau, Katharina Haigh, Christian M Nefzger, Reyhan Akhtar, Thomas Gridley, Geert Berx, Jody J Haigh, Nick Barker, Jose M Polo, Gary R Hime, and Helen E Abud

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COCATS 4 Task Force 2: Training in Preventive Cardiovascular Medicine., Sidney C Smith, Vera Bittner, J Michael Gaziano, John C Giacomini, Quinn R Pack, Donna M Polk, Neil J Stone, and Stanley Wang

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Assessment of medical student and resident/fellow knowledge, comfort, and training with sexual history taking in LGBTQ patients., Victoria Hayes, Whitney Blondeau, and Robert G Bing-You

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Combined volume reduction with the loop-and-leave technique permits safe endoscopic management of high-risk giant gastric polyps., Suraj Gupta, Joshua Penfield, David Klibansy, and Douglas A. Howell

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Development of an algorithm to classify colonoscopy indication from coded health care data., Kenneth F. Adams, Eric A. Johnson, Jessica Chubak, Aruna Kamineni, Chyke A. Doubeni, Diana S M Buist, Andrew E. Williams, Sheila Weinmann, V Paul Doria-Rose, and Carolyn M. Rutter

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Gonadotropin-releasing hormone agonist use to guide diagnosis and treatment of autoimmune progesterone dermatitis., Amy Domeyer-Klenske, Diana Robillard, John Pulvino, and Daniel Spratt

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Let's Go! School nutrition workgroups: regional partnerships for improving school meals., Heidi L Kessler, Jackie Vine, and Victoria W Rogers

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Loss of Snail2 favors skin tumor progression by promoting the recruitment of myeloid progenitors., Ana Villarejo, Patricia Molina-Ortiz, Yenny Montenegro, Gema Moreno-Bueno, Saleta Morales, Vanesa Santos, Tom Gridley, Mirna A Pérez-Moreno, Héctor Peinado, Francisco Portillo, Carmela Calés, and Amparo Cano

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Mo1380 Early ERCP Placement of Short Self-Expanding Metal Biliary Stents (SSEMS) in Locally-Advanced Pancreatic Cancer With Biliary Obstruction Improves Success and Outcomes of Neoadjuvant Therapy., Suraj Gupta, John Walker, Hani Jarawan, Lewis B. Richards, David Klibanksy, Douglas A. Howell, Justin Wilkes, Gina Z. Blaszyk, and Lisa A. Rutstein

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Neurologic outcomes and postresuscitation care of patients with myoclonus following cardiac arrest., David B Seder, Kjetil Sunde, Sten Rubertsson, Michael Mooney, Pascal Stammet, Richard R Riker, Karl B Kern, Barbara Unger, Tobias Cronberg, John Dziodzio, and Niklas Nielsen

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Prognostic significance of tumor mitotic rate in T2 melanoma staged with sentinel lymphadenectomy., Justin J Baker, Michael O Meyers, Allison M Deal, Jill F Frank, Karyn B Stitzenberg, and David W Ollila

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Review of Smashed: Story of a drunken girlhood., Sandra L. Fritsch

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Su1622 Cannulation of Intradiverticular Papillae At ERCP: a Successful Stepwise Approach Using Advanced Techniques., Hani Jarawan, Suraj Gupta, John Walker, Joshua Penfield, and Douglas A. Howell

Submersion and Drowning Injuries., Sara W. Nelson and Scott C. McCorvey

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Tu1731 Safe Definitive Endoscopic Management of High-Risk Polypoid Lesions of the Foregut Using Combined Volume Reduction and the Loop and Leave Technique., John Walker, Suraj Gupta, Hani Jarawan, Joshua Penfield, David Klibansky, and Douglas A. Howell

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Association of gender to outcome after out-of-hospital cardiac arrest--a report from the International Cardiac Arrest Registry., Viktor Karlsson, Josef Dankiewicz, Niklas Nielsen, Karl B Kern, Michael R Mooney, Richard R Riker, Sten Rubertsson, David B Seder, Pascal Stammet, Kjetil Sunde, Eldar Søreide, Barbara T Unger, and Hans Friberg

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Prevalence and risk factors for patient-reported joint pain among patients with HIV/hepatitis C coinfection, hepatitis C monoinfection, and HIV monoinfection., Alexis Ogdie, Wyki Gina Pang, Kimberly A Forde, Bhangle D Samir, Lakeisha Mulugeta, Kyong-Mi Chang, David E Kaplan, Valerianna K Amorosa, Jay R Kostman, Rajender K Reddy, Ralph H Schumacher, and Vincent Lo Re

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Calcium and phosphorus regulatory hormones and risk of incident symptomatic kidney stones., Eric N Taylor, Andrew N Hoofnagle, and Gary C Curhan

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A phase I feasibility study of multi-modality imaging assessing rapid expansion of marrow fat and decreased bone mineral density in cancer patients., Susanta K Hui, Luke Arentsen, Thanasak Sueblinvong, Keenan Brown, Pat Bolan, Rahel G Ghebre, Levi Downs, Ryan Shanley, Karen E Hansen, Anne G Minenko, Yutaka Takhashi, Masashi Yagi, Yan Zhang, Melissa Geller, Margaret Reynolds, Chung K Lee, Anne H Blaes, Sharon Allen, Bruno Beomonte Zobel, Chap Le, Jerry Froelich, Clifford Rosen, and Douglas Yee

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A structured teaching curriculum for medical students improves their performance on the National Board of Medical Examiners shelf examination in surgery., Keith Wirth, Bethany Malone, Christopher Turner, Robert Schulze, Warren Widmann, and Aliu Sanni

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Emergency medicine residents' knowledge of mechanical ventilation., Susan R Wilcox, Todd A Seigel, Tania D Strout, Jeffrey I Schneider, Patricia M Mitchell, Evie G Marcolini, Michael N Cocchi, Howard A Smithline, Lucienne Lutfy-Clayton, Marie Mullen, Jonathan S Ilgen, and Jeremy B Richards

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Methadone versus morphine for treatment of neonatal abstinence syndrome: a prospective randomized clinical trial., M S Brown, M J Hayes, and L M Thornton

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Noninvasive prenatal testing: the importance of pretest trisomy risk and posttest predictive values., Joseph R Wax, Renee Chard, Angelina Cartin, Christian Litton, Michael G Pinette, and F Lee Lucas

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p53 Enables metabolic fitness and self-renewal of nephron progenitor cells., Yuwen Li, Jiao Liu, Wencheng Li, Aaron Brown, Melody Baddoo, Marilyn Li, Thomas Carroll, Leif Oxburgh, Yumei Feng, and Zubaida Saifudeen

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Participation in the Vascular Quality Initiative is associated with improved perioperative medication use, which is associated with longer patient survival., Randall R De Martino, Andrew W Hoel, Adam W Beck, Jens Eldrup-Jorgensen, John W Hallett, Gilbert R Upchurch, Jack L Cronenwett, and Philip P Goodney

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Scapulothoracic fusion for low-energy intrathoracic scapula dislocation: a report of two cases., Donald P Endrizzi, Daniel J Shubert, and Raymond R White

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Serotonin syndrome following methylene blue administration during cardiothoracic surgery., Christina J Smith, Dorothy Wang, Anna Sgambelluri, Robert S Kramer, and David J Gagnon

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Success rates in pediatric WPW ablation are improved with 3-dimensional mapping systems compared with fluoroscopy alone: a multicenter study., Scott R Ceresnak, Anne M Dubin, Jeffrey J Kim, Santiago O Valdes, Steven B Fishberger, Ira Shetty, Frank Zimmerman, Ronn E Tanel, Michael R Epstein, Kara S Motonaga, Christine A Capone, Lynn Nappo, Gregory J Gates, and Robert H Pass

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Air contamination with bacteria in cystic fibrosis clinics: implications for prevention strategies., Jonathan B Zuckerman, Sarah A Clock, B Stephen Prato, James J McDevitt, Juyan Julia Zhou, Laurie W Leclair, F Lee Lucas, and Lisa Saiman

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"Clinical and functional outcomes after 2 years in the early detection and intervention for the prevention of psychosis multisite effectiveness trial": Erratum., William R. McFarlane, Bruce Levin, Lori Travis, F Lee Lucas, Sarah Lynch, Mary Verdi, Deanna Williams, Steven Adelsheim, Roderick Calkins, Cameron S. Carter, Barbara Cornblatt, Stephan F. Taylor, Andrea M. Auther, Bentson McFarland, Ryan Melton, Margaret Migliorati, Tara Niendam, J Daniel Ragland, Tamar Sale, Melina Salvador, and Elizabeth Spring

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Decisions about medication use and cancer screening across age groups in the United States., Kathleen M Fairfield, Bethany S Gerstein, Carrie A Levin, Vickie Stringfellow, Heidi R Wierman, and Mary McNaughton-Collins

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Distal hypospadias repair in infants without a postoperative stent., David J Chalmers, Georgette L Siparsky, Cole A Wiedel, and Duncan T Wilcox

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Gender differences in the person-activity fit for positive psychology interventions., R Bruce Thompson, Christine Peura, and William F. Gayton

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Hypertension, living kidney donors, and transplantation: where are we today?, Ana P Rossi and John P Vella

Paravertebral analgesia in transapical transcatheter aortic valve replacement., Justin M. Poltak, Frederick C. Cobey, John G. Augoustides, and Christopher W. Connors

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Physical activity, energy intake and the risk of incident kidney stones., Pietro Manuel Ferraro, Gary C Curhan, Mathew D Sorensen, Giovanni Gambaro, and Eric N Taylor

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SLEAP: a wake-up call to question the oversimplification of ICU delirium., Gilles L Fraser, David J Gagnon, and Richard R Riker

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The interface of child mental health and juvenile diabetes mellitus., Sandra L Fritsch, Mark W Overton, and Douglas R Robbins

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Transition from dexmedetomidine to enteral clonidine for ICU sedation: an observational pilot study., David J Gagnon, Richard R Riker, Elizabeth K Glisic, Andrew Kelner, Hilary M Perrey, and Gilles L Fraser

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Vaginal anomalies and atresia associated with imperforate anus: diagnosis and surgical management., Kartikey A Pandya, Hiroyuki Koga, Manabu Okawada, Arnold G Coran, Atsuyuki Yamataka, and Daniel H Teitelbaum

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Stones, bones, and cardiovascular groans., Eric N Taylor

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Integrated β-catenin, BMP, PTEN, and Notch signalling patterns the nephron., Nils O Lindström, Melanie L Lawrence, Sally F Burn, Jeanette A Johansson, Elvira R M Bakker, Rachel A Ridgway, C-Hong Chang, Michele J Karolak, Leif Oxburgh, Denis J Headon, Owen J Sansom, Ron Smits, Jamie A Davies, and Peter Hohenstein

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American Medical Society for Sports Medicine (AMSSM) position statement: interventional musculoskeletal ultrasound in sports medicine., Jonathan T Finnoff, Mederic M Hall, Erik Adams, David Berkoff, Andrew L Concoff, William Dexter, and Jay Smith

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American Medical Society for Sports Medicine (AMSSM) position statement: interventional musculoskeletal ultrasound in sports medicine., Jonathan T Finnoff, Mederic M Hall, Erik Adams, David Berkoff, Andrew L Concoff, William Dexter, and Jay Smith

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Bundled payments in orthopaedics., Adam J Rana and Kevin J Bozic

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Burden of hospital admissions and utilization of hospice care in metastatic prostate cancer patients., Jesse D Sammon, Rana R McKay, Simon P Kim, Akshay Sood, Shyam Sukumar, Matthew H Hayn, Jim C Hu, Adam S Kibel, Paul L Nguyen, James O Peabody, Fred Saad, Maxine Sun, Briony Varda, Mani Menon, Toni K Choueiri, and Quoc-Dien Trinh

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Decision making and cancer., Valerie F Reyna, Wendy L Nelson, Paul K Han, and Michael P Pignone

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Human parechovirus-3 encephalitis in two neonates: acute and follow-up magnetic resonance imaging and evaluation of central nervous system markers of inflammation., Amanda D Brownell, Thomas Q Reynolds, Brian Livingston, and Carol A McCarthy

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Key articles and guidelines in the management of patients undergoing cardiac surgery., Ian B Hollis, Douglas L Jennings, Carrie S Oliphant, William L Baker, Estella M Davis, J Erin Allender, Wesley R Zemrak, and Christopher Ensor

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Moderate-dose sedation and analgesia during targeted temperature management after cardiac arrest., Teresa L May, David B Seder, Gilles L Fraser, Philip Stone, Barbara McCrum, and Richard R Riker

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Prospective series of two hours supine rest after 4fr sheath-based diagnostic cerebral angiography: outcomes, productivity and cost., Scott L Zuckerman, Ritwik Bhatia, Crystiana Tsujiara, Christopher B Baker, Alex Szafran, Deborah Cushing, Judy Aiken, Marilyn Tracy, J Mocco, and Robert D Ecker

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The bone-fat interface: basic and clinical implications of marrow adiposity., Maureen J Devlin and Clifford J Rosen

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The Maine Adolescent Council on Transition (ACT Maine): A resident-driven, Community Access to Child Health (CATCH) Grant Funded Project to Improve the Quality of Health Care Transition and Build Resilience in Youth With Chronic Illness and Their..., Jack C. Rusley, Jessica Hunt, David Buzanoski, Renata Arrington-Sanders, Jonathan T. Fanburg, and Patrice Thibodeau

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Using vascular quality initiative as a platform for organizing multicenter, prospective, randomized clinical trials: OVERPAR trial., Mohammad H Eslami, Gheorghe Doros, Philip P Goodney, Jens Elderup-Jorgenson, Jack L Cronenwett, Marina Malikova, and Alik Farber

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Compositions and Methods for Treating Inflammation and Fibrosis, Peter C. Brooks, Leif Oxburgh, and Jennifer M. Caron

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3,5-diiodo-L-thyronine (t2) in dietary supplements: what are the physiological effects?, Arturo Hernandez

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Analgesia, sedation, and neuromuscular blockade during targeted temperature management after cardiac arrest., Richard R Riker, David J Gagnon, Teresa May, David B Seder, and Gilles L Fraser

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A qualitative study of patient and family perceptions of chaplain presence during post-trauma care., Steven C McCormick and Alice A Hildebrand

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A young man with abdominal trauma and inability to void., Janessa D Leger, George L Higgins, and Matthew T Opacic

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Barriers to employment for drug dependent postpartum women., Kelley Bowden and Daisy Goodman

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BMP9 crosstalk with the hippo pathway regulates endothelial cell matricellular and chemokine responses., Kira Young, Eric Tweedie, Barbara Conley, Jacquelyn Ames, MaryLynn FitzSimons, Peter Brooks, Lucy Liaw, and Calvin P H Vary

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Changing Medicine and Building Community: Maine's Adverse Childhood Experiences Momentum., Leslie Forstadt, Sally Cooper, and Sue Mackey Andrews

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Characterizing participants in the ClinSeq genome sequencing cohort as early adopters of a new health technology., Katie L Lewis, Paul K J Han, Gillian W Hooker, William M P Klein, Leslie G Biesecker, and Barbara B Biesecker

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Clinical and functional outcomes after 2 years in the early detection and intervention for the prevention of psychosis multisite effectiveness trial., William R McFarlane, Bruce Levin, Lori Travis, F Lee Lucas, Sarah Lynch, Mary Verdi, Deanna Williams, Steven Adelsheim, Roderick Calkins, Cameron S Carter, Barbara Cornblatt, Stephan F Taylor, Andrea M Auther, Bentson McFarland, Ryan Melton, Margaret Migliorati, Tara Niendam, J Daniel Ragland, Tamara Sale, Melina Salvador, and Elizabeth Spring

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Current orthopaedic surgeon practices for nonarthroplasty treatment of osteoarthritis of adult hip and knee., Justin Chang, Brian J McGrory, Adam Rana, Michael W Becker, George M Babikian, Peter Guay, and Kahsi A Smith

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Emergency neurological life support: airway, ventilation, and sedation., David B Seder, Andy Jagoda, and Becky Riggs

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Evolution from electrophysiologic to hemodynamic monitoring: the story of left atrial and pulmonary artery pressure monitors., Deirdre M Mooney, Erik Fung, Rahul N Doshi, and David M Shavelle

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Identification of Emergency department patients with acute heart failure at low risk for 30-day adverse events: The STRATIFY decision tool., Sean P Collins, Cathy A Jenkins, Frank E Harrell, Dandan Liu, Karen F Miller, Christopher J Lindsell, Allen J Naftilan, John A McPherson, David J Maron, Douglas B Sawyer, Neal L Weintraub, Gregory J Fermann, Susan K Roll, Matthew Sperling, and Alan B Storrow

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Inhibition of tumor-associated αvβ3 integrin regulates the angiogenic switch by enhancing expression of IGFBP-4 leading to reduced melanoma growth and angiogenesis in vivo., Liangru W Contois, Abebe Akalu, Jennifer M Caron, Eric Tweedie, Alexandra Cretu, Terry Henderson, Lucy Liaw, Robert Friesel, Calvin Vary, and Peter C Brooks

Long-term tattooing as a manifestation of metallosis in acetabular liner wear-through: a report of two cases., Malcolm Creighton-Smith, Brian J. McGrory, and Ioana Tolocica

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Mortality related to acute illness and injury in rural Uganda: task shifting to improve outcomes., Stacey Chamberlain, Uwe Stolz, Bradley Dreifuss, Sara W Nelson, Heather Hammerstedt, Jovita Andinda, Samuel Maling, and Mark Bisanzo

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Noninvasive prenatal testing: impact on genetic counseling, invasive prenatal diagnosis, and trisomy 21 detection., Joseph R Wax, Angelina Cartin, Renée Chard, F Lee Lucas, and Michael G Pinette

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Operative indications in recurrent ileocolic intussusception., Jeremy G Fisher, Eric A Sparks, Christopher G B Turner, Justin D Klein, Elliot Pennington, Faraz A Khan, David Zurakowski, Emily T Durkin, Dario O Fauza, and Biren P Modi

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Paravertebral analgesia in transapical transcatheter aortic valve replacement., Justin M Poltak, Frederick C Cobey, John G Augoustides, and Christopher W Connors

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Pediatric primary care providers' perspectives regarding hospital discharge communication: a mixed methods analysis., JoAnna K Leyenaar, Lora Bergert, Leah A Mallory, Richard Engel, Caroline Rassbach, Mark Shen, Tess Woehrlen, David Cooperberg, and Daniel Coghlin

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Pediatric sutureless circumcision: an effective and cost efficient alternative., Maria Voznesensky, Christopher Mutter, Matthew Hayn, Thomas Kinkead, and Brian Jumper

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Prenatal aneuploidy screening using cell-free DNA., Joseph R Wax, Renée Chard, Christian Litton, and Michael G Pinette

Primary Site Predicts Grade for Gastroenteropancreatic Neuroendocrine Tumors., Timothy L. Fitzgerald, Catalina Mosquera, C Suzanne Lea, and Matthew Mcmullen

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Promoting a perception of quietness on a telemetry unit., Cecilia Inman

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PTHrp comes full circle in cancer biology., Anyonya R Guntur, Casey R Doucette, and Clifford J Rosen

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Sailing smoothly across the cultural divide: constructing effective behavioral science presentations for medical audiences., Linda Myerholtz, Julie Schirmer, and Mary Anne Carling

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Self-reported treatment-associated symptoms among patients with urea cycle disorders participating in glycerol phenylbutyrate clinical trials., Sandesh C S Nagamani, George A Diaz, William Rhead, Susan A Berry, Cynthia Le Mons, Uta Lichter-Konecki, James Bartley, Annette Feigenbaum, Andreas Schulze, Nicola Longo, William Berquist, Renata Gallagher, Dennis Bartholomew, Cary O Harding, Mark S Korson, Shawn E McCandless, Wendy Smith, Jerry Vockley, David Kronn, Robert Zori, Stephen Cederbaum, J Lawrence Merritt, Derek Wong, Dion F Coakley, Bruce F Scharschmidt, Klara Dickinson, Miguel Marino, Brendan H Lee, and Masoud Mokhtarani

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Successful eculizumab treatment of recurrent postpartum atypical hemolytic uremic syndrome after kidney transplantation., Katherine Garlo, Doug Dressel, Marizela Savic, and John Vella

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Symptomatic infundibulopelvic dysgenesis in an adolescent., Daniel Pitts, David Chalmers, and Brian Jumper

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The autism inpatient collection: methods and preliminary sample description., Matthew Siegel, Kahsi A Smith, Carla Mazefsky, Robin L Gabriels, Craig Erickson, Desmond Kaplan, Eric M Morrow, Logan Wink, and Susan L Santangelo

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Transparent reporting of data quality in distributed data networks., Michael G Kahn, Jeffrey S Brown, Alein T Chun, Bruce N Davidson, Daniella Meeker, Patrick B Ryan, Lisa M Schilling, Nicole G Weiskopf, Andrew E Williams, and Meredith Nahm Zozus

Submissions from 2014

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Syndrome of severe pain associated with a continuous bumetanide infusion., David Shisler, Thomas M Austin, Eric Delpire, Douglas B Sawyer, and Arvind K Pandey

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Inducible models of bone loss., Casey R Doucette and Clifford J Rosen

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Effects of a renal rehabilitation exercise program in patients with CKD: a randomized, controlled trial., Ana P Rossi, Debra D Burris, F Leslie Lucas, Gail A Crocker, and James C Wasserman

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Assessing volume status and fluid responsiveness in the emergency department., David C Mackenzie and Vicki E Noble

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Caffeine intake and the risk of kidney stones., Pietro Manuel Ferraro, Eric N Taylor, Giovanni Gambaro, and Gary C Curhan

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Circulating sclerostin associated with vertebral bone marrow fat in older men but not women., Yu-Heng Vivian Ma, Ann V Schwartz, Sigurdur Sigurdsson, Trisha F Hue, Thomas F Lang, Tamara B Harris, Clifford J Rosen, Eric Vittinghoff, Gudny Eiriksdottir, Alda M Hauksdottir, Kristin Siggeirsdottir, Gunnar Sigurdsson, Diana Oskarsdottir, Nicola Napoli, Lisa Palermo, Vilmundur Gudnason, and Xiaojuan Li

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Clinical monitoring scales in acute brain injury: assessment of coma, pain, agitation, and delirium., Richard R Riker and Jennifer E Fugate

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Copper binding affinity of the C2B domain of synaptotagmin-1 and its potential role in the nonclassical secretion of acidic fibroblast growth factor., Srinivas Jayanthi, Karuppanan Muthusamy Kathir, Dakshinamurthy Rajalingam, Mercede Furr, Anna Daily, Ryan Thurman, Lindsay Rutherford, Reena Chandrashekar, Paul Adams, Igor Prudovsky, and Thallapuranam Krishnaswamy Suresh Kumar

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Evaluation of anesthetic technique on surgical site infections (SSIs) at a single institution., Craig S Curry, Kahsi A Smith, and John W Allyn

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How do research participants perceive "uncertainty" in genome sequencing?, Barbara B Biesecker, William Klein, Katie L Lewis, Tyler C Fisher, Martha Frances Wright, Leslie G Biesecker, and Paul K Han

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Implementation of the systems approach to improve a pharmacist-managed vancomycin dosing service., David J Gagnon, Russel Roberts, and Lynne Sylvia

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Improving patients' readiness for coronary artery bypass graft surgery., Kristine Chaisson, Mary Sanford, Richard A Boss, Bruce J Leavitt, Michael J Hearne, Cathy S Ross, Elaine M Olmstead, Robert S Kramer, Patricia Hofmaster, Cathy Mingo, Dennis Duquette, Elizabeth Maislen, Jean A Clark, Donald S Likosky, Susan R Horton, Gerald T O'Connor, and David J Malenka

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Individual differences in aversion to ambiguity regarding medical tests and treatments: association with cancer screening cognitions., Paul K J Han, Andrew E Williams, Amy Haskins, Caitlin Gutheil, F Lee Lucas, William M P Klein, and Kathleen M Mazor

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Outcomes and unmet need for neonatal surgery in a resource-limited environment: estimates of global health disparities from Kampala, Uganda., Raghav Badrinath, Nasser Kakembo, Phyllis Kisa, Monica Langer, Doruk Ozgediz, and John Sekabira